ES479300A1 - Procedimiento de obtencio de &-metil, 4(2'tienil carbonilz) fenil acetato de p-acetamido fenol. - Google Patents

Procedimiento de obtencio de &-metil, 4(2'tienil carbonilz) fenil acetato de p-acetamido fenol.

Info

Publication number
ES479300A1
ES479300A1 ES479300A ES479300A ES479300A1 ES 479300 A1 ES479300 A1 ES 479300A1 ES 479300 A ES479300 A ES 479300A ES 479300 A ES479300 A ES 479300A ES 479300 A1 ES479300 A1 ES 479300A1
Authority
ES
Spain
Prior art keywords
thienyl
carbonyl
methyl
alpha
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES479300A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Cusi SA
Original Assignee
Laboratorios Cusi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Cusi SA filed Critical Laboratorios Cusi SA
Priority to ES479300A priority Critical patent/ES479300A1/es
Publication of ES479300A1 publication Critical patent/ES479300A1/es
Priority to CA000349213A priority patent/CA1158655A/en
Priority to JP4452280A priority patent/JPS55147275A/ja
Priority to AT80301106T priority patent/ATE2220T1/de
Priority to DE8080301106T priority patent/DE3061578D1/de
Priority to EP80301106A priority patent/EP0018732B1/en
Priority to US06/323,992 priority patent/US4352935A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento de obtención de alpha-metil,4(2¿tienil carbonil)fenil acetato de p-acetamido fenol. Util como agente antiinflamatorio y cuya fórmula es: ***1 (Ver fórmula 1)
ES479300A 1979-04-04 1979-04-04 Procedimiento de obtencio de &-metil, 4(2'tienil carbonilz) fenil acetato de p-acetamido fenol. Expired ES479300A1 (es)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ES479300A ES479300A1 (es) 1979-04-04 1979-04-04 Procedimiento de obtencio de &-metil, 4(2'tienil carbonilz) fenil acetato de p-acetamido fenol.
CA000349213A CA1158655A (en) 1979-04-04 1980-04-03 PROCESS FOR OBTAINING P-ACETAMIDO PHENOL .alpha.-METHYL-4(2'THIENYL-CARBONYL)-PHENYL ACETATE
JP4452280A JPS55147275A (en) 1979-04-04 1980-04-03 Ppacetamidophenollalphaamethyll4*2**thienyll carbonyl*phenylacetate and its use and manufacture
AT80301106T ATE2220T1 (de) 1979-04-04 1980-04-08 Derivat der alpha-methyl-4(2'-thienylcarbonyl)phenylessigs[ure, verfahren zu seiner herstellung und seine pharmazeutische verwendung.
DE8080301106T DE3061578D1 (en) 1979-04-04 1980-04-08 An alpha-methyl-4(2'-thienyl-carbonyl)phenyl acetic acid derivative, process for its preparation and its pharmaceutical use
EP80301106A EP0018732B1 (en) 1979-04-04 1980-04-08 An alpha-methyl-4(2'-thienyl-carbonyl)phenyl acetic acid derivative, process for its preparation and its pharmaceutical use
US06/323,992 US4352935A (en) 1979-04-04 1981-11-23 Process for obtaining P-acetamido phenol α-methyl-4(2'thienyl-carbonyl) phenyl acetate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES479300A ES479300A1 (es) 1979-04-04 1979-04-04 Procedimiento de obtencio de &-metil, 4(2'tienil carbonilz) fenil acetato de p-acetamido fenol.

Publications (1)

Publication Number Publication Date
ES479300A1 true ES479300A1 (es) 1979-07-01

Family

ID=8477987

Family Applications (1)

Application Number Title Priority Date Filing Date
ES479300A Expired ES479300A1 (es) 1979-04-04 1979-04-04 Procedimiento de obtencio de &-metil, 4(2'tienil carbonilz) fenil acetato de p-acetamido fenol.

Country Status (7)

Country Link
US (1) US4352935A (es)
EP (1) EP0018732B1 (es)
JP (1) JPS55147275A (es)
AT (1) ATE2220T1 (es)
CA (1) CA1158655A (es)
DE (1) DE3061578D1 (es)
ES (1) ES479300A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102863350A (zh) * 2011-07-06 2013-01-09 中国科学院大连化学物理研究所 非甾体抗炎药抗炎镇痛协同前药及其制备方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610830B1 (en) 1980-07-01 2003-08-26 Hoffman-La Roche Inc. Microbial production of mature human leukocyte interferons

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4159986A (en) * 1969-11-12 1979-07-03 Roussel Uclaf Novel thiophene-acetic acids
FR2201883B1 (es) * 1972-10-05 1975-10-31 Roussel Uclaf
CA1007643A (en) * 1972-10-24 1977-03-29 Janssen Pharmaceutica Naamloze Vennootschap Aroyl-substituted phenylacetic acid derivatives
US4035376A (en) * 1972-10-24 1977-07-12 Janssen Pharmaceutica N.V. Aroyl-substituted phenylacetic acid derivatives
US4064132A (en) * 1975-10-08 1977-12-20 Janssen Pharmaceutica N.V. Aroyl-substituted phenylacetamide derivatives
US4153718A (en) * 1976-07-30 1979-05-08 Beecham Group Limited Anti-inflammatory compounds
ES460926A1 (es) * 1977-07-21 1978-05-16 Cusi Lab Procedimiento de obtencion de sales de acidos arilalcanoicoscon aminoacidos dibasicos.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102863350A (zh) * 2011-07-06 2013-01-09 中国科学院大连化学物理研究所 非甾体抗炎药抗炎镇痛协同前药及其制备方法
CN102863350B (zh) * 2011-07-06 2015-06-17 中国科学院大连化学物理研究所 非甾体抗炎镇痛协同前药及其制备方法

Also Published As

Publication number Publication date
EP0018732A1 (en) 1980-11-12
CA1158655A (en) 1983-12-13
DE3061578D1 (en) 1983-02-17
ATE2220T1 (de) 1983-01-15
US4352935A (en) 1982-10-05
JPS6125716B2 (es) 1986-06-17
EP0018732B1 (en) 1983-01-12
JPS55147275A (en) 1980-11-17

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