JPS54100384A - Novel penicillamine derivative - Google Patents

Novel penicillamine derivative

Info

Publication number
JPS54100384A
JPS54100384A JP786978A JP786978A JPS54100384A JP S54100384 A JPS54100384 A JP S54100384A JP 786978 A JP786978 A JP 786978A JP 786978 A JP786978 A JP 786978A JP S54100384 A JPS54100384 A JP S54100384A
Authority
JP
Japan
Prior art keywords
formula
lower alkyl
penicillamine
compound
aromatic heterocyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP786978A
Other languages
Japanese (ja)
Inventor
Masaki Shiraki
Yutaka Maruyama
Kazuhiro Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP786978A priority Critical patent/JPS54100384A/en
Publication of JPS54100384A publication Critical patent/JPS54100384A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:Penicillamine derivatives of formula I (R1 is lower alkyl; R2 is aryl, aralkyl, aromatic heterocyclic ring, lower alkyl substituted with aromatic heterocyclic rind; A is lower alkylene).
EXAMPLE: 5-Benzamide-3-ethoxycarbonylmethyl-6,6-dimethyl-2-thioxotetrahydro- 2H-1,3-thiazine-4-one.
USE: Anti-inflammatory, antirheumatic, immunosuppresive, antibiotic, analgesic, and anticarcinostatic agents.
PREPARATION: The reaction between a penicillamine compound of formula II (R3 is H, lower alkyl) and a little excess amount of isothiocyanate of formula III is effected in an inert solvent, when necessary, in the presence of a condensation agent as pyridine or hydrochloric acid at room temperature to 150, preferably 50 - 100°C, to prepare the compound of formula I.
COPYRIGHT: (C)1979,JPO&Japio
JP786978A 1978-01-25 1978-01-25 Novel penicillamine derivative Pending JPS54100384A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP786978A JPS54100384A (en) 1978-01-25 1978-01-25 Novel penicillamine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP786978A JPS54100384A (en) 1978-01-25 1978-01-25 Novel penicillamine derivative

Publications (1)

Publication Number Publication Date
JPS54100384A true JPS54100384A (en) 1979-08-08

Family

ID=11677633

Family Applications (1)

Application Number Title Priority Date Filing Date
JP786978A Pending JPS54100384A (en) 1978-01-25 1978-01-25 Novel penicillamine derivative

Country Status (1)

Country Link
JP (1) JPS54100384A (en)

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