JPS54100384A - Novel penicillamine derivative - Google Patents
Novel penicillamine derivativeInfo
- Publication number
- JPS54100384A JPS54100384A JP786978A JP786978A JPS54100384A JP S54100384 A JPS54100384 A JP S54100384A JP 786978 A JP786978 A JP 786978A JP 786978 A JP786978 A JP 786978A JP S54100384 A JPS54100384 A JP S54100384A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- lower alkyl
- penicillamine
- compound
- aromatic heterocyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:Penicillamine derivatives of formula I (R1 is lower alkyl; R2 is aryl, aralkyl, aromatic heterocyclic ring, lower alkyl substituted with aromatic heterocyclic rind; A is lower alkylene).
EXAMPLE: 5-Benzamide-3-ethoxycarbonylmethyl-6,6-dimethyl-2-thioxotetrahydro- 2H-1,3-thiazine-4-one.
USE: Anti-inflammatory, antirheumatic, immunosuppresive, antibiotic, analgesic, and anticarcinostatic agents.
PREPARATION: The reaction between a penicillamine compound of formula II (R3 is H, lower alkyl) and a little excess amount of isothiocyanate of formula III is effected in an inert solvent, when necessary, in the presence of a condensation agent as pyridine or hydrochloric acid at room temperature to 150, preferably 50 - 100°C, to prepare the compound of formula I.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP786978A JPS54100384A (en) | 1978-01-25 | 1978-01-25 | Novel penicillamine derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP786978A JPS54100384A (en) | 1978-01-25 | 1978-01-25 | Novel penicillamine derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS54100384A true JPS54100384A (en) | 1979-08-08 |
Family
ID=11677633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP786978A Pending JPS54100384A (en) | 1978-01-25 | 1978-01-25 | Novel penicillamine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54100384A (en) |
-
1978
- 1978-01-25 JP JP786978A patent/JPS54100384A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5432460A (en) | Cycloalkylidenemethylphenylacetic acid derivative and their preparation | |
JPS56103168A (en) | Thiazole derivative, its preparation, and antihistaminic agent containing the same | |
JPS57136579A (en) | Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same | |
JPS57116074A (en) | Novel camptothecin derivative and its preparation | |
JPS54100384A (en) | Novel penicillamine derivative | |
JPS5528955A (en) | Novel glycerophosphoric acid derivative, its salt, their preparation, and carcinostatic agent containing the same. | |
JPS5576852A (en) | Novel derivative of anthranilic acid | |
JPS5692261A (en) | Novel cyclohexanecarboxylic derivative and its preparation | |
JPS5540645A (en) | Benzopyrone derivative | |
JPS5772981A (en) | 1,8-naphthyridine derivative and its salt | |
JPS5527142A (en) | Novel 1-phthalazone derivative | |
JPS5566560A (en) | Quinolone derivative | |
JPS52100473A (en) | Novel azimidebenzamide derivative and its production | |
JPS55104274A (en) | Isoxazolin-3-one derivative and its preparation | |
JPS5566592A (en) | 7-alkoxythiazolo 3,2-a pyrimidine derivative, its preparation, and drug containing the same | |
JPS54115356A (en) | 1-substituted-5,6,-dithiocalicene derivative and its preparation | |
JPS55149300A (en) | Thiasteroid analog compound and its preapration | |
JPS57197258A (en) | Sulfonic ester derivative and its preparation | |
JPS527946A (en) | Preparation of indanylpropionic acid derivatives | |
JPS5359656A (en) | Silacyclopropene derivatives and process for preparation of the same | |
JPS5612393A (en) | Novel camptothecin derivative | |
JPS5549386A (en) | Heterocyclic compound and its acid addition salt | |
JPS5711975A (en) | Aminophenyltetrazole derivative and salt thereof | |
JPS554334A (en) | Pyranopyrazole derivative | |
JPS5227757A (en) | Preparation of 6-aminomethylnaphthalene derivatives |