ES472817A1 - Un procedimiento para preparar analogos de tiadiazolil-cefa-losporina - Google Patents

Un procedimiento para preparar analogos de tiadiazolil-cefa-losporina

Info

Publication number
ES472817A1
ES472817A1 ES472817A ES472817A ES472817A1 ES 472817 A1 ES472817 A1 ES 472817A1 ES 472817 A ES472817 A ES 472817A ES 472817 A ES472817 A ES 472817A ES 472817 A1 ES472817 A1 ES 472817A1
Authority
ES
Spain
Prior art keywords
thienyl
thiadiazolyl
compounds
hydroxyphenyl
carboxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES472817A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of ES472817A1 publication Critical patent/ES472817A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Un procedimiento para preparar análogos de tiadiazolil-cefalosporina de la fórmula siguiente o sus derivados reactivos: **(Fórmula)** (donde Ar es 2-tienilo, 3-tienilo, fenilo, p-hidroxifenilo, p-aciloxifenilo ó p-hidroxifenilo protegido; COB1 y COB2 son cada uno de ellos carboxi o carboxi protegido; y R es hidrógeno o alcohilo inferior) que comprende tratar una amina de la fórmula siguiente o un derivado reactivo de la misma.
ES472817A 1977-08-25 1978-08-24 Un procedimiento para preparar analogos de tiadiazolil-cefa-losporina Expired ES472817A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52102261A JPS609718B2 (ja) 1977-08-25 1977-08-25 チアジアゾリルチオセフアロスポリン類縁抗生物質

Publications (1)

Publication Number Publication Date
ES472817A1 true ES472817A1 (es) 1979-02-16

Family

ID=14322642

Family Applications (1)

Application Number Title Priority Date Filing Date
ES472817A Expired ES472817A1 (es) 1977-08-25 1978-08-24 Un procedimiento para preparar analogos de tiadiazolil-cefa-losporina

Country Status (34)

Country Link
US (1) US4201782A (es)
JP (1) JPS609718B2 (es)
AR (1) AR220539A1 (es)
AT (1) AT361121B (es)
AU (1) AU517618B2 (es)
BE (1) BE869955A (es)
BG (1) BG34338A3 (es)
CA (1) CA1101417A (es)
CH (1) CH637396A5 (es)
CS (1) CS203927B2 (es)
DD (1) DD137230A5 (es)
DE (1) DE2837264A1 (es)
DK (1) DK372878A (es)
ES (1) ES472817A1 (es)
FI (1) FI65432C (es)
FR (1) FR2401165A1 (es)
GB (1) GB1576796A (es)
GR (1) GR70260B (es)
HU (1) HU177900B (es)
IE (1) IE47630B1 (es)
IL (1) IL55429A0 (es)
IT (1) IT1118098B (es)
MX (1) MX5328E (es)
NL (1) NL190554C (es)
NO (1) NO782866L (es)
NZ (1) NZ188173A (es)
PH (1) PH17508A (es)
PL (1) PL110656B1 (es)
PT (1) PT68434A (es)
RO (1) RO75070A (es)
SE (1) SE452010B (es)
SU (1) SU812182A3 (es)
YU (1) YU43999B (es)
ZA (1) ZA784753B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4259485A (en) * 1979-04-24 1981-03-31 Eli Lilly And Company Crystallization process
FR2494279A1 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouvelles oxacephalosporines, leur preparation et les medicaments qui les contiennent
DE3373475D1 (en) * 1982-12-14 1987-10-15 Beecham Group Plc Process for the preparation of beta-lactam compounds
JPS60123490A (ja) * 1983-12-07 1985-07-02 Shionogi & Co Ltd マロニルオキサセフェムカルボン酸誘導体
US6013835A (en) * 1995-06-07 2000-01-11 Hfm International, Inc. Method and apparatus for preparing purified terephthalic acid
US6197794B1 (en) 1998-01-08 2001-03-06 Celltech Therapeutics Limited Phenylalanine derivatives
US6329372B1 (en) 1998-01-27 2001-12-11 Celltech Therapeutics Limited Phenylalanine derivatives
ATE273273T1 (de) 1998-02-26 2004-08-15 Celltech Therapeutics Ltd Phenylalaninderivate als inhibitoren von alpha4 integrinen
GB9805655D0 (en) 1998-03-16 1998-05-13 Celltech Therapeutics Ltd Chemical compounds
US6521626B1 (en) 1998-03-24 2003-02-18 Celltech R&D Limited Thiocarboxamide derivatives
GB9811159D0 (en) 1998-05-22 1998-07-22 Celltech Therapeutics Ltd Chemical compounds
GB9811969D0 (en) 1998-06-03 1998-07-29 Celltech Therapeutics Ltd Chemical compounds
GB9812088D0 (en) 1998-06-05 1998-08-05 Celltech Therapeutics Ltd Chemical compounds
GB9814414D0 (en) 1998-07-03 1998-09-02 Celltech Therapeutics Ltd Chemical compounds
GB9821061D0 (en) 1998-09-28 1998-11-18 Celltech Therapeutics Ltd Chemical compounds
GB9821222D0 (en) 1998-09-30 1998-11-25 Celltech Therapeutics Ltd Chemical compounds
GB9821406D0 (en) * 1998-10-01 1998-11-25 Celltech Therapeutics Ltd Chemical compounds
GB9825652D0 (en) 1998-11-23 1999-01-13 Celltech Therapeutics Ltd Chemical compounds
US6518283B1 (en) 1999-05-28 2003-02-11 Celltech R&D Limited Squaric acid derivatives
US6534513B1 (en) 1999-09-29 2003-03-18 Celltech R&D Limited Phenylalkanoic acid derivatives
US6455539B2 (en) 1999-12-23 2002-09-24 Celltech R&D Limited Squaric acid derivates
EP1332132B1 (en) 2000-04-17 2007-10-10 UCB Pharma, S.A. Enamine derivatives as cell adhesion molecules
US6545013B2 (en) 2000-05-30 2003-04-08 Celltech R&D Limited 2,7-naphthyridine derivatives
US6403608B1 (en) 2000-05-30 2002-06-11 Celltech R&D, Ltd. 3-Substituted isoquinolin-1-yl derivatives
AU2001267753A1 (en) 2000-07-07 2002-01-21 Celltech R And D Limited Squaric acid derivatives containing a bicyclic heteroaromatic ring as integrin antagonists
US6649756B2 (en) * 2000-07-13 2003-11-18 Wyeth, Five Giralda Farms Process improvement in the preparation of (4r, 5s, 6s)-3-[[(2r,3r)-2-[[[(s)-2-amino-3-methyl-1-oxobutyl]amino]methyl]tetrahydro-3-furanyl]thio]-6-[(r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
AU2001275724A1 (en) 2000-08-02 2002-02-13 Celltech R&D Limited 3-substituted isoquinolin-1-yl derivatives
CN102827191B (zh) * 2012-09-24 2015-03-11 浙江东邦药业有限公司 一种氧头孢类化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL178005C (nl) * 1972-11-06 1986-01-02 Merck & Co Inc Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking, alsmede werkwijze ter bereiding van een cefalosporine-antibioticum.
US4045438A (en) * 1975-10-24 1977-08-30 Yeda Research And Development Co. Ltd. Cephalosporin antibiotics
US4031083A (en) * 1975-10-24 1977-06-21 Yeda Research And Development Co., Ltd. Cephalosporin antibiotics
CA1070688A (en) * 1975-11-12 1980-01-29 Mitsuru Yoshioka Cephalosporin analogues
CA1085392A (en) * 1976-03-25 1980-09-09 Masayuki Narisada Arylmalonamido-1-oxadethiacephalosporins

Also Published As

Publication number Publication date
NZ188173A (en) 1981-05-15
GB1576796A (en) 1980-10-15
AR220539A1 (es) 1980-11-14
ZA784753B (en) 1979-08-29
MX5328E (es) 1983-06-22
AT361121B (de) 1981-02-25
AU517618B2 (en) 1981-08-13
ATA620378A (de) 1980-07-15
NL190554B (nl) 1993-11-16
NL190554C (nl) 1994-04-18
NL7808802A (nl) 1979-02-27
DK372878A (da) 1979-02-26
YU43999B (en) 1990-02-28
RO75070A (ro) 1980-10-30
DD137230A5 (de) 1979-08-22
IL55429A0 (en) 1978-10-31
FR2401165A1 (fr) 1979-03-23
PH17508A (en) 1984-09-07
DE2837264A1 (de) 1979-03-01
AU3923878A (en) 1980-02-28
PT68434A (en) 1978-09-01
IE47630B1 (en) 1984-05-16
FI65432B (fi) 1984-01-31
CS203927B2 (en) 1981-03-31
NO782866L (no) 1979-02-27
US4201782A (en) 1980-05-06
GR70260B (es) 1982-09-02
DE2837264C2 (es) 1991-06-13
PL209215A1 (pl) 1979-06-04
PL110656B1 (en) 1980-07-31
BG34338A3 (en) 1983-08-15
IT1118098B (it) 1986-02-24
FI65432C (fi) 1984-05-10
IT7868975A0 (it) 1978-08-24
FR2401165B1 (es) 1982-06-25
CH637396A5 (de) 1983-07-29
JPS609718B2 (ja) 1985-03-12
YU202878A (en) 1982-10-31
SU812182A3 (ru) 1981-03-07
BE869955A (fr) 1978-12-18
CA1101417A (en) 1981-05-19
IE781703L (en) 1979-02-25
JPS5436288A (en) 1979-03-16
SE7808950L (sv) 1979-02-26
HU177900B (en) 1982-01-28
SE452010B (sv) 1987-11-09
FI782586A (fi) 1979-02-26

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971201