ES471120A1 - Procedimiento y sistema para analizar particulas que se en- cuentran en suspension en un liquido - Google Patents
Procedimiento y sistema para analizar particulas que se en- cuentran en suspension en un liquidoInfo
- Publication number
- ES471120A1 ES471120A1 ES471120A ES471120A ES471120A1 ES 471120 A1 ES471120 A1 ES 471120A1 ES 471120 A ES471120 A ES 471120A ES 471120 A ES471120 A ES 471120A ES 471120 A1 ES471120 A1 ES 471120A1
- Authority
- ES
- Spain
- Prior art keywords
- electrodes
- auxiliary
- liquid
- channel
- potential difference
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002245 particle Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 abstract 4
- 230000002596 correlated effect Effects 0.000 abstract 2
- 238000005070 sampling Methods 0.000 abstract 2
- 210000000601 blood cell Anatomy 0.000 abstract 1
- 230000000875 corresponding effect Effects 0.000 abstract 1
- 230000001960 triggered effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
- G01N15/131—Details
- G01N15/132—Circuits
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Abstract
Procedimiento para analizar partículas que se encuentran en suspensión en un líquido, particularmente glóbulos sanguíneos, con dos recipientes para la suspensión separados por una pared aislante, un canal longitudinal que atraviesa la pared, dos electrodos de alimentación conectados a sendos polos de una alimentación eléctrica y que están en contacto con el líquido en cada uno de los recipientes, por lo menos un electrodo adicional que está en contacto con el líquido en el canal, cuyas dimensiones paralelas en la dirección longitudinal del canal son pequeñas en proporción con la longitud del canal, y medios sensores, de los cuales cada vez uno de ellos está asignado a un par de electrodos para determinar las variaciones en el curso del tiempo de la diferencia de potencial entre estos electrodos, caracterizado porque se forma un valor auxiliar asignado al transcurso de tiempo de la diferencia de potencial entre un electrodo adicional determinado y uno de los otros electrodos y un valor de medición asignado al transcurso de tiempo de la diferencia de potencial entre dos de los otros electrodos, y porque se dispara una exploración del valor de medición para obtener un valor de exploración correspondiente a una partícula en función del valor auxiliar.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH784277A CH614781A5 (es) | 1977-06-27 | 1977-06-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES471120A1 true ES471120A1 (es) | 1979-01-01 |
Family
ID=4331230
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES471120A Expired ES471120A1 (es) | 1977-06-27 | 1978-06-26 | Procedimiento y sistema para analizar particulas que se en- cuentran en suspension en un liquido |
Country Status (13)
Country | Link |
---|---|
US (1) | US4161690A (es) |
JP (1) | JPS5412794A (es) |
BE (1) | BE867676A (es) |
CA (1) | CA1103312A (es) |
CH (1) | CH614781A5 (es) |
DE (1) | DE2824831C3 (es) |
DK (1) | DK146984C (es) |
ES (1) | ES471120A1 (es) |
FR (1) | FR2396285B1 (es) |
GB (1) | GB1602134A (es) |
IT (1) | IT1096003B (es) |
NL (1) | NL188308C (es) |
SE (1) | SE438554B (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4438390A (en) | 1981-03-23 | 1984-03-20 | Coulter Electronics, Inc. | Tandem sensing zones for improved signal-to-noise ratio in particle analyzer |
US4488116A (en) * | 1981-09-22 | 1984-12-11 | Mars, Incorporated | Inductive coin sensor for measuring more than one parameter of a moving coin |
US4510438A (en) * | 1982-02-16 | 1985-04-09 | Coulter Electronics, Inc. | Coincidence correction in particle analysis system |
DE3411936A1 (de) * | 1983-03-31 | 1984-10-11 | Eduard Dr.med. Stäfa Bretschger | Teilchenzaehleinrichtung und verfahren zu deren betrieb |
US4607526A (en) * | 1984-12-21 | 1986-08-26 | Allied Corporation | Particle analysis system |
DE3522186A1 (de) * | 1985-06-21 | 1987-01-02 | Hoechst Ag | Messeinrichtung zum messen des verformungsvermoegens von roten blutkoerperchen |
GB8606299D0 (en) * | 1986-03-14 | 1986-04-23 | Holley J E F | Scanner |
US4977517A (en) * | 1988-09-21 | 1990-12-11 | Toni Diagnostics, Inc. | Leak and clog detection and removal system for use with particle counters |
CA1315127C (en) * | 1989-02-03 | 1993-03-30 | Raynald Hachey | Apparatus for particle determination in liquid metals |
CA1328679C (en) * | 1989-05-18 | 1994-04-19 | Raynald Hachey | Apparatus for particle determination in liquid metals |
GB2232769B (en) * | 1989-06-13 | 1994-06-22 | Timothy Charles Fisher | Counting and volume measurement of particles and biological cells,and determination of their deformability |
US5376878A (en) * | 1991-12-12 | 1994-12-27 | Fisher; Timothy C. | Multiple-aperture particle counting sizing and deformability-measuring apparatus |
US6111398A (en) * | 1997-07-03 | 2000-08-29 | Coulter International Corp. | Method and apparatus for sensing and characterizing particles |
US6175227B1 (en) | 1997-07-03 | 2001-01-16 | Coulter International Corp. | Potential-sensing method and apparatus for sensing and characterizing particles by the Coulter principle |
CA2229528A1 (en) | 1998-02-13 | 1999-08-13 | Shailesh Mehta | Apparatus and method for analyzing particles |
US6259242B1 (en) * | 1999-05-26 | 2001-07-10 | Coulter International Corp. | Apparatus incorporating a sensing conduit in conductive material and method of use thereof for sensing and characterizing particles |
ES2758033T3 (es) | 2004-03-04 | 2020-05-04 | Novelis Inc | Configuración de electrodo para LIMCA |
US9121843B2 (en) | 2007-05-08 | 2015-09-01 | Trustees Of Boston University | Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof |
JP2012524908A (ja) * | 2009-04-24 | 2012-10-18 | ベックマン コールター, インコーポレイテッド | 粒子を特徴づける方法 |
AU2010301128B2 (en) | 2009-09-30 | 2014-09-18 | Quantapore, Inc. | Ultrafast sequencing of biological polymers using a labeled nanopore |
US9651539B2 (en) | 2012-10-28 | 2017-05-16 | Quantapore, Inc. | Reducing background fluorescence in MEMS materials by low energy ion beam treatment |
AU2014268322B2 (en) | 2013-05-24 | 2019-01-24 | Quantapore, Inc. | Nanopore-based nucleic acid analysis with mixed FRET detection |
JP6740222B2 (ja) | 2014-10-10 | 2020-08-12 | クアンタポール, インコーポレイテッド | 互いに消光する蛍光標識とのナノポアを基礎にしたポリマー分析 |
CN107002126B (zh) | 2014-10-24 | 2021-05-25 | 昆塔波尔公司 | 使用纳米结构阵列的聚合物的高效光学分析 |
US10823721B2 (en) | 2016-07-05 | 2020-11-03 | Quantapore, Inc. | Optically based nanopore sequencing |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2996917A (en) * | 1958-02-13 | 1961-08-22 | Walter P Christoph | Electrolytic apparatus for temperature and radiation measurements |
US3801901A (en) * | 1970-10-27 | 1974-04-02 | Coulter Electronics | Particle study apparatus including an axial trajectory sensor |
US3821644A (en) * | 1971-04-26 | 1974-06-28 | H Gohde | Device for automatic counting and measurement of suspended particles |
CH546437A (de) * | 1972-06-30 | 1974-02-28 | Contraves Ag | Verfahren und einrichtung zur kompensation der temperaturabhaengigkeit einer fluessigkeit bei der bestimmung von in derselben suspendierten teilchen. |
US3973194A (en) * | 1972-08-07 | 1976-08-03 | Becton, Dickinson And Company | Particle counter |
-
1977
- 1977-06-27 CH CH784277A patent/CH614781A5/xx not_active IP Right Cessation
-
1978
- 1978-05-31 BE BE188211A patent/BE867676A/xx not_active IP Right Cessation
- 1978-05-31 GB GB24917/78A patent/GB1602134A/en not_active Expired
- 1978-06-05 US US05/912,927 patent/US4161690A/en not_active Expired - Lifetime
- 1978-06-06 DK DK250878A patent/DK146984C/da active
- 1978-06-06 DE DE2824831A patent/DE2824831C3/de not_active Expired
- 1978-06-09 CA CA305,148A patent/CA1103312A/en not_active Expired
- 1978-06-15 NL NLAANVRAGE7806472,A patent/NL188308C/xx not_active IP Right Cessation
- 1978-06-20 IT IT24714/78A patent/IT1096003B/it active
- 1978-06-22 SE SE7807163A patent/SE438554B/sv not_active IP Right Cessation
- 1978-06-26 ES ES471120A patent/ES471120A1/es not_active Expired
- 1978-06-26 JP JP7662578A patent/JPS5412794A/ja active Granted
- 1978-06-27 FR FR7819183A patent/FR2396285B1/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2396285B1 (es) | 1985-03-08 |
SE438554B (sv) | 1985-04-22 |
NL188308C (nl) | 1992-05-18 |
IT7824714A0 (it) | 1978-06-20 |
GB1602134A (en) | 1981-11-04 |
US4161690A (en) | 1979-07-17 |
FR2396285A1 (es) | 1979-01-26 |
DK250878A (da) | 1978-12-28 |
BE867676A (fr) | 1978-09-18 |
NL188308B (nl) | 1991-12-16 |
DK146984C (da) | 1984-08-13 |
DE2824831B2 (de) | 1980-03-13 |
DK146984B (da) | 1984-03-05 |
DE2824831A1 (de) | 1979-01-04 |
CA1103312A (en) | 1981-06-16 |
IT1096003B (it) | 1985-08-17 |
NL7806472A (nl) | 1978-12-29 |
SE7807163L (sv) | 1978-12-28 |
CH614781A5 (es) | 1979-12-14 |
DE2824831C3 (de) | 1980-11-06 |
JPS5412794A (en) | 1979-01-30 |
JPS629850B2 (es) | 1987-03-03 |
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