ES459777A1 - Un procedimiento para la preparacion de un nuevo derivado detiofilinilo. - Google Patents
Un procedimiento para la preparacion de un nuevo derivado detiofilinilo.Info
- Publication number
- ES459777A1 ES459777A1 ES459777A ES4597A ES459777A1 ES 459777 A1 ES459777 A1 ES 459777A1 ES 459777 A ES459777 A ES 459777A ES 4597 A ES4597 A ES 4597A ES 459777 A1 ES459777 A1 ES 459777A1
- Authority
- ES
- Spain
- Prior art keywords
- carboyl
- group
- theophyllinylacetic
- acid
- acyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Un procedimiento para la preparación de un nuevo derivado de tiofilinilo de fórmula (I): *** donde R es un átomo de hidrógeno o un grupo metilo; n es un número entero de 1 a 4 y ``acilo¿¿ es un grupo nicotinoilo, 3-metilpirazol-5-carboilo, 3-metilisoxazolil-5-carboilo, 5-n-butilpiridin-2-carboilo, 2-(4-clorofenoxi)-2-metil-propionilo, 2-acetoxibenzoilo o teofinil-7-acetilo, cuyo procedimiento consiste en hacer reaccionar un compuesto de fórmula (V) X-CHR-(CH2)n ¿ O ¿ acilo con ácido teofilinilacético o un derivado acilante del mismo, donde R, n y X es un grupo hidroxilo o un grupo fácilmente desplazable.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752512886 DE2512886A1 (de) | 1975-03-24 | 1975-03-24 | Neue ester der theophyllinyl-7- essigsaeure, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittelpraeparate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES459777A1 true ES459777A1 (es) | 1978-04-01 |
Family
ID=5942253
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES446321A Expired ES446321A1 (es) | 1975-03-24 | 1976-03-24 | Un procedimiento para la preparacion de un nuevo derivado deteofilinilo. |
| ES459777A Expired ES459777A1 (es) | 1975-03-24 | 1977-06-14 | Un procedimiento para la preparacion de un nuevo derivado detiofilinilo. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES446321A Expired ES446321A1 (es) | 1975-03-24 | 1976-03-24 | Un procedimiento para la preparacion de un nuevo derivado deteofilinilo. |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS6043352B2 (es) |
| AR (2) | AR211336A1 (es) |
| AT (1) | AT344191B (es) |
| BE (1) | BE839890A (es) |
| CA (1) | CA1051890A (es) |
| CH (1) | CH605950A5 (es) |
| DK (1) | DK140843B (es) |
| ES (2) | ES446321A1 (es) |
| FI (1) | FI760755A (es) |
| FR (1) | FR2305184A1 (es) |
| GB (1) | GB1496298A (es) |
| HU (1) | HU174879B (es) |
| IE (1) | IE42788B1 (es) |
| NL (1) | NL7603103A (es) |
| SE (2) | SE419864B (es) |
| ZA (1) | ZA761801B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2714883A1 (de) * | 1977-04-02 | 1978-10-12 | Basf Ag | Nicht-glykosidische theophyllin- zucker-derivate |
-
1976
- 1976-03-18 GB GB10871/76A patent/GB1496298A/en not_active Expired
- 1976-03-19 FR FR7608048A patent/FR2305184A1/fr active Granted
- 1976-03-22 BE BE165447A patent/BE839890A/xx not_active IP Right Cessation
- 1976-03-22 FI FI760755A patent/FI760755A/fi not_active Application Discontinuation
- 1976-03-22 IE IE601/76A patent/IE42788B1/en unknown
- 1976-03-22 AT AT209376A patent/AT344191B/de not_active IP Right Cessation
- 1976-03-23 JP JP51031891A patent/JPS6043352B2/ja not_active Expired
- 1976-03-23 SE SE7603564A patent/SE419864B/xx unknown
- 1976-03-23 DK DK128076AA patent/DK140843B/da not_active IP Right Cessation
- 1976-03-23 CA CA248,568A patent/CA1051890A/en not_active Expired
- 1976-03-24 CH CH365876A patent/CH605950A5/xx not_active IP Right Cessation
- 1976-03-24 HU HU76WU24A patent/HU174879B/hu unknown
- 1976-03-24 ZA ZA761801A patent/ZA761801B/xx unknown
- 1976-03-24 NL NL7603103A patent/NL7603103A/xx not_active Application Discontinuation
- 1976-03-24 ES ES446321A patent/ES446321A1/es not_active Expired
- 1976-03-26 AR AR262675A patent/AR211336A1/es active
- 1976-11-08 AR AR265378A patent/AR217246A1/es active
-
1977
- 1977-06-14 ES ES459777A patent/ES459777A1/es not_active Expired
-
1979
- 1979-03-19 SE SE7902463A patent/SE7902463L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU174879B (hu) | 1980-03-28 |
| BE839890A (fr) | 1976-09-22 |
| AT344191B (de) | 1978-07-10 |
| ZA761801B (en) | 1977-03-30 |
| CA1051890A (en) | 1979-04-03 |
| GB1496298A (en) | 1977-12-30 |
| FR2305184B1 (es) | 1979-09-21 |
| FR2305184A1 (fr) | 1976-10-22 |
| SE7902463L (sv) | 1979-03-19 |
| ATA209376A (de) | 1977-11-15 |
| DK140843B (da) | 1979-11-26 |
| NL7603103A (nl) | 1976-09-28 |
| DK140843C (es) | 1980-04-28 |
| JPS51118794A (en) | 1976-10-18 |
| DK128076A (es) | 1976-09-25 |
| IE42788B1 (en) | 1980-10-22 |
| AR211336A1 (es) | 1977-11-30 |
| JPS6043352B2 (ja) | 1985-09-27 |
| SE7603564L (sv) | 1976-09-25 |
| AR217246A1 (es) | 1980-03-14 |
| ES446321A1 (es) | 1977-10-01 |
| SE419864B (sv) | 1981-08-31 |
| IE42788L (en) | 1976-09-24 |
| FI760755A (es) | 1976-09-25 |
| CH605950A5 (es) | 1978-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980202 |