ES435930A1 - A procedure for the preparation of tiazolidinon-acetic acid derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of tiazolidinon-acetic acid derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES435930A1
ES435930A1 ES435930A ES435930A ES435930A1 ES 435930 A1 ES435930 A1 ES 435930A1 ES 435930 A ES435930 A ES 435930A ES 435930 A ES435930 A ES 435930A ES 435930 A1 ES435930 A1 ES 435930A1
Authority
ES
Spain
Prior art keywords
translation
procedure
preparation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES435930A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2414345A external-priority patent/DE2414345C3/en
Priority claimed from DE2506410A external-priority patent/DE2506410C3/en
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of ES435930A1 publication Critical patent/ES435930A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A procedure for the preparation of thiazolidinon-acetic acid derivatives, of the general formula ** (See formula) ** in which R1 is a lower alkyl with 1 to 4 carbon atoms, and its pharmaceutically acceptable salts, of diuretic activity in mammals, characterized in that a compound of the general formula is treated at low temperature: ** (See formula) ** in which R1 has the meaning indicated above and R2 is an alkyl radical containing from 2 to 6 carbon atoms, with an approximately 40% solution of hydrogen bromide in an inorganic acid of 1 to 5 carbon atoms, and why below The acid mixture is separated and the amino acid is isolated. (Machine-translation by Google Translate, not legally binding)
ES435930A 1974-03-25 1975-03-24 A procedure for the preparation of tiazolidinon-acetic acid derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES435930A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2414345A DE2414345C3 (en) 1974-03-25 1974-03-25 (Z) - (3-Methyl-4-oxo-5-piperidinothiazolidin-2-ylidene) acetic acid and process for the preparation of thiazolidine acetic acid derivatives
DE2506410A DE2506410C3 (en) 1975-02-15 1975-02-15 Process for the preparation of thiazolidinone acetic acid derivatives

Publications (1)

Publication Number Publication Date
ES435930A1 true ES435930A1 (en) 1977-03-16

Family

ID=25766870

Family Applications (1)

Application Number Title Priority Date Filing Date
ES435930A Expired ES435930A1 (en) 1974-03-25 1975-03-24 A procedure for the preparation of tiazolidinon-acetic acid derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (10)

Country Link
AT (1) AT340416B (en)
CH (1) CH594664A5 (en)
DK (1) DK140725B (en)
ES (1) ES435930A1 (en)
FI (1) FI59801C (en)
FR (1) FR2265375B1 (en)
GB (1) GB1437170A (en)
NL (1) NL7503395A (en)
NO (1) NO141801C (en)
SE (1) SE415352B (en)

Also Published As

Publication number Publication date
FI750895A (en) 1975-09-26
ATA229075A (en) 1977-04-15
CH594664A5 (en) 1978-01-13
NO750983L (en) 1975-09-26
DK140725B (en) 1979-11-05
GB1437170A (en) 1976-05-26
FR2265375A1 (en) 1975-10-24
DK140725C (en) 1980-03-31
FI59801C (en) 1981-10-12
NO141801C (en) 1980-06-04
NL7503395A (en) 1975-09-29
FR2265375B1 (en) 1978-08-04
DK108675A (en) 1975-09-26
SE7503380L (en) 1975-09-26
AT340416B (en) 1977-12-12
FI59801B (en) 1981-06-30
SE415352B (en) 1980-09-29
NO141801B (en) 1980-02-04

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