ES424067A1 - Procedimiento de preparacion de dihidro - 5,6 (4h) - (s) - triazolo - (3,3 - a) - benzodiazepinas - 1,5. - Google Patents
Procedimiento de preparacion de dihidro - 5,6 (4h) - (s) - triazolo - (3,3 - a) - benzodiazepinas - 1,5.Info
- Publication number
- ES424067A1 ES424067A1 ES424067A ES424067A ES424067A1 ES 424067 A1 ES424067 A1 ES 424067A1 ES 424067 A ES424067 A ES 424067A ES 424067 A ES424067 A ES 424067A ES 424067 A1 ES424067 A1 ES 424067A1
- Authority
- ES
- Spain
- Prior art keywords
- disclosed
- class
- triazolobenzodiazepines
- benzodiazepines
- triazolo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7308510A FR2220257A1 (en) | 1973-03-09 | 1973-03-09 | 5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects |
FR7335522A FR2246273A2 (en) | 1973-10-04 | 1973-10-04 | 5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects |
FR7341583A FR2252102A2 (en) | 1973-11-22 | 1973-11-22 | 5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects |
Publications (1)
Publication Number | Publication Date |
---|---|
ES424067A1 true ES424067A1 (es) | 1976-06-01 |
Family
ID=27250074
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES424067A Expired ES424067A1 (es) | 1973-03-09 | 1974-03-08 | Procedimiento de preparacion de dihidro - 5,6 (4h) - (s) - triazolo - (3,3 - a) - benzodiazepinas - 1,5. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4110337A (es) |
JP (1) | JPS49125395A (es) |
CA (1) | CA1011333A (es) |
CH (1) | CH589084A5 (es) |
DD (1) | DD110497A5 (es) |
DE (1) | DE2409308C3 (es) |
DK (1) | DK139099B (es) |
ES (1) | ES424067A1 (es) |
GB (1) | GB1409693A (es) |
IE (1) | IE38931B1 (es) |
IL (1) | IL44338A (es) |
NL (1) | NL7403247A (es) |
NO (1) | NO139048C (es) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4076823A (en) * | 1977-08-18 | 1978-02-28 | E. R. Squibb & Sons, Inc. | Triazolo-2,4-benzodiazepines |
US5683998A (en) * | 1991-04-23 | 1997-11-04 | Toray Industries, Inc. | Tricyclic triazolo derivatives, processes for producing the same and the uses of the same |
WO1992018505A1 (en) * | 1991-04-23 | 1992-10-29 | Toray Industries, Inc. | Tricyclic triazole derivative, production thereof, and use thereof |
FR2769309B1 (fr) | 1997-10-08 | 2001-06-15 | Oreal | Composition de teinture d'oxydation des fibres keratiniques comprenant un derive d'aminoacide en tant que base d'oxydation et nouveaux derives d'aminoacides |
US7276348B2 (en) * | 1999-04-30 | 2007-10-02 | Regents Of The University Of Michigan | Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof |
JP5127096B2 (ja) | 1999-04-30 | 2013-01-23 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | アポトーシスにより誘導される自己免疫疾患を処置するためのベンゾジアゼピンの使用 |
US7572788B2 (en) * | 1999-04-30 | 2009-08-11 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
US20030119029A1 (en) * | 1999-04-30 | 2003-06-26 | Regents Of The University Of Michigan | Compositions and methods relating to novel benzodiazepine compounds and targets thereof |
US20060025388A1 (en) | 1999-04-30 | 2006-02-02 | Glick Gary D | Compositions and methods relating to novel compounds and targets thereof |
US20040176358A1 (en) * | 1999-04-30 | 2004-09-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
US20050113460A1 (en) * | 1999-04-30 | 2005-05-26 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
US20050272723A1 (en) * | 2004-04-27 | 2005-12-08 | The Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
US20060052369A1 (en) * | 2004-09-07 | 2006-03-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
CA2593019A1 (en) * | 2005-01-03 | 2006-07-13 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
JP2008545757A (ja) * | 2005-06-01 | 2008-12-18 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 溶媒和されていないベンゾジアゼピン組成物および方法 |
US20070105844A1 (en) * | 2005-10-26 | 2007-05-10 | Regents Of The University Of Michigan | Therapeutic compositions and methods |
CA2779041A1 (en) | 2005-11-01 | 2007-05-10 | The Regents Of The University Of Michigan | Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties |
DE102005061840A1 (de) | 2005-12-23 | 2007-06-28 | Merck Patent Gmbh | Triazolderivate |
US7759338B2 (en) * | 2006-04-27 | 2010-07-20 | The Regents Of The University Of Michigan | Soluble 1,4 benzodiazepine compounds and stable salts thereof |
MX2008015488A (es) | 2006-06-09 | 2009-02-12 | Univ Michigan | Composiciones y metodos relacionados con compuestos novedosos y objetivos de los mismos. |
AU2008226532B2 (en) | 2007-03-09 | 2011-09-22 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
MX2010002732A (es) | 2007-09-14 | 2010-06-02 | Univ Michigan | Inhibidores de f1f0-atpasa y metodos relacionados. |
KR20100083819A (ko) | 2007-11-06 | 2010-07-22 | 더 리젠츠 오브 더 유니버시티 오브 미시간 | 피부 병태의 치료에 유용한 벤조디아제피논 화합물 |
WO2010030891A2 (en) | 2008-09-11 | 2010-03-18 | The Regents Of The University Of Michigan | Aryl guanidine f1f0-atpase inhibitors and related methods |
WO2010121164A2 (en) | 2009-04-17 | 2010-10-21 | The Regents Of The University Of Michigan | 1,4-benzodiazepinone compounds and their use in treating cancer |
EP2470020A4 (en) | 2009-09-18 | 2013-03-13 | Univ Michigan | BENZODIAZEPINONE COMPOUNDS AND TREATMENT METHODS THEREWITH |
JP5856064B2 (ja) | 2009-11-17 | 2016-02-09 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 治療特性を有する1,4−ベンゾジアゼピン−2,5−ジオンおよび関連化合物 |
JP5856063B2 (ja) | 2009-11-17 | 2016-02-09 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 治療特性を有する1,4−ベンゾジアゼピン−2,5−ジオンおよび関連化合物 |
WO2012075456A1 (en) | 2010-12-02 | 2012-06-07 | Constellation Pharmaceuticals | Bromodomain inhibitors and uses thereof |
AR084070A1 (es) | 2010-12-02 | 2013-04-17 | Constellation Pharmaceuticals Inc | Inhibidores del bromodominio y usos de los mismos |
EP2705039B1 (en) * | 2011-05-04 | 2017-07-26 | Constellation Pharmaceuticals, Inc. | Bromodomain inhibitors and uses thereof |
US9328117B2 (en) | 2011-06-17 | 2016-05-03 | Constellation Pharmaceuticals, Inc. | Bromodomain inhibitors and uses thereof |
US9624244B2 (en) | 2012-06-06 | 2017-04-18 | Constellation Pharmaceuticals, Inc. | Benzo [B] isoxazoloazepine bromodomain inhibitors and uses thereof |
TWI602820B (zh) | 2012-06-06 | 2017-10-21 | 星宿藥物公司 | 溴域抑制劑及其用途 |
TR201906788T4 (tr) | 2014-06-20 | 2019-05-21 | Constellation Pharmaceuticals Inc | 2-((4s)-6-(4-klorofenil)-1-metil-4h-benzo[c]izoksazolo[4,5-e]azepın-4-il)asetamidin kristal formları. |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3681343A (en) * | 1971-05-11 | 1972-08-01 | Upjohn Co | 6-phenyl-s-triazolo{8 4,3-a{9 {8 1,4{9 {0 benzodiazepines |
-
1974
- 1974-02-26 IE IE00393/74A patent/IE38931B1/xx unknown
- 1974-02-27 DE DE2409308A patent/DE2409308C3/de not_active Expired
- 1974-03-04 IL IL44338A patent/IL44338A/en unknown
- 1974-03-07 GB GB1035574A patent/GB1409693A/en not_active Expired
- 1974-03-08 CH CH332374A patent/CH589084A5/xx not_active IP Right Cessation
- 1974-03-08 CA CA194,513A patent/CA1011333A/en not_active Expired
- 1974-03-08 US US05/449,477 patent/US4110337A/en not_active Expired - Lifetime
- 1974-03-08 ES ES424067A patent/ES424067A1/es not_active Expired
- 1974-03-08 NO NO740833A patent/NO139048C/no unknown
- 1974-03-08 DD DD177060A patent/DD110497A5/xx unknown
- 1974-03-08 DK DK125874AA patent/DK139099B/da unknown
- 1974-03-09 JP JP49026797A patent/JPS49125395A/ja active Pending
- 1974-03-11 NL NL7403247A patent/NL7403247A/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE2409308B2 (de) | 1977-09-22 |
NO740833L (no) | 1974-09-10 |
GB1409693A (en) | 1975-10-15 |
DD110497A5 (es) | 1974-12-20 |
NL7403247A (es) | 1974-09-11 |
DE2409308C3 (de) | 1978-05-18 |
DK139099B (da) | 1978-12-18 |
IL44338A (en) | 1977-01-31 |
CA1011333A (en) | 1977-05-31 |
AU6627674A (en) | 1975-09-11 |
DE2409308A1 (de) | 1974-09-19 |
IE38931L (en) | 1974-09-09 |
DK139099C (es) | 1979-05-28 |
CH589084A5 (es) | 1977-06-30 |
US4110337A (en) | 1978-08-29 |
NO139048B (no) | 1978-09-18 |
IE38931B1 (en) | 1978-07-05 |
IL44338A0 (en) | 1974-06-30 |
NO139048C (no) | 1979-01-03 |
JPS49125395A (es) | 1974-11-30 |
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