ES411675A1 - Procedure for obtaining antibacterial compositions. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for obtaining antibacterial compositions. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES411675A1 ES411675A1 ES411675A ES411675A ES411675A1 ES 411675 A1 ES411675 A1 ES 411675A1 ES 411675 A ES411675 A ES 411675A ES 411675 A ES411675 A ES 411675A ES 411675 A1 ES411675 A1 ES 411675A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- translation
- procedure
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000000844 anti-bacterial effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229930182555 Penicillin Natural products 0.000 abstract 2
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 abstract 1
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
- C07C275/58—Y being a hetero atom
- C07C275/60—Y being an oxygen atom, e.g. allophanic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Procedure for obtaining antibacterial compositions, characterized in that penicillins of general formula I are prepared in a first stage ** (See formula) ** wherein R is phenyl, R'is methyl and R''is dimethylamino, these compounds of the aforementioned main general formula being presented, as regards the center of chirality (see formula) as one of the two possible diastereomers with the R or S configuration or as mixtures of these two diastereomers, as well as their pharmaceutically tolerable non-toxic salts, by reaction of 6-aminopenicillanic acid of formula II ** (See formula) ** with carboxylic acids modified in the carboxyl group of general formula III ** (See formula) ** in which R, R'and R''' have the meanings specified above, the reaction being carried out in anhydrous solvents or containing water in the presence of a base; and in a second step, the resulting penicillin is mixed with a pharmaceutically acceptable vehicle. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2025415A DE2025415C3 (en) | 1970-05-25 | 1970-05-25 | Process for the preparation of cyclic acylureido penicillins |
| DE19712104579 DE2104579C3 (en) | 1971-02-01 | 1971-02-01 | Cyclic acylureidopenicillins and medicinal products containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES411675A1 true ES411675A1 (en) | 1976-01-01 |
Family
ID=25759180
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES391533A Expired ES391533A1 (en) | 1970-05-25 | 1971-05-25 | Procedure for the obtaining of penicillines. (Machine-translation by Google Translate, not legally binding) |
| ES411676A Expired ES411676A1 (en) | 1970-05-25 | 1973-02-16 | Procedure for obtaining antibacterial compositions. (Machine-translation by Google Translate, not legally binding) |
| ES411674A Expired ES411674A1 (en) | 1970-05-25 | 1973-02-16 | Procedure for obtaining antibacterial compositions. (Machine-translation by Google Translate, not legally binding) |
| ES411675A Expired ES411675A1 (en) | 1970-05-25 | 1973-02-16 | Procedure for obtaining antibacterial compositions. (Machine-translation by Google Translate, not legally binding) |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES391533A Expired ES391533A1 (en) | 1970-05-25 | 1971-05-25 | Procedure for the obtaining of penicillines. (Machine-translation by Google Translate, not legally binding) |
| ES411676A Expired ES411676A1 (en) | 1970-05-25 | 1973-02-16 | Procedure for obtaining antibacterial compositions. (Machine-translation by Google Translate, not legally binding) |
| ES411674A Expired ES411674A1 (en) | 1970-05-25 | 1973-02-16 | Procedure for obtaining antibacterial compositions. (Machine-translation by Google Translate, not legally binding) |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS55390B1 (en) |
| AT (1) | AT306924B (en) |
| BE (1) | BE767648A (en) |
| BG (1) | BG23753A3 (en) |
| CA (1) | CA932722A (en) |
| CH (1) | CH571524A5 (en) |
| CS (1) | CS185564B2 (en) |
| CY (1) | CY830A (en) |
| DD (1) | DD91496B3 (en) |
| DK (1) | DK134438C (en) |
| EG (1) | EG10490A (en) |
| ES (4) | ES391533A1 (en) |
| FI (1) | FI54485C (en) |
| FR (1) | FR2100682B1 (en) |
| GB (1) | GB1301962A (en) |
| IE (1) | IE35404B1 (en) |
| IL (1) | IL36904A (en) |
| KE (1) | KE2591A (en) |
| LU (1) | LU63204A1 (en) |
| NL (1) | NL172659C (en) |
| NO (1) | NO141759C (en) |
| PH (1) | PH12110A (en) |
| RO (1) | RO59290A (en) |
| SE (1) | SE395895B (en) |
| SU (1) | SU420181A3 (en) |
| YU (1) | YU35889B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2260118C2 (en) * | 1972-12-08 | 1982-06-03 | Bayer Ag, 5090 Leverkusen | Penicillins and their use as medicines |
| DE2354219A1 (en) * | 1973-10-30 | 1975-05-07 | Bayer Ag | BETA-LACTAM-ANTIBIOTICA, A PROCESS FOR THEIR MANUFACTURING AND ITS USE AS A MEDICINAL PRODUCT |
| US4039673A (en) | 1973-10-30 | 1977-08-02 | Bayer Aktiengesellschaft | Penicillins and cephalosporins and their production |
| GB1486349A (en) * | 1974-11-28 | 1977-09-21 | Bayer Ag | Beta-lactam antibiotics process for their preparation and their use as medicaments |
| GB1584400A (en) * | 1976-12-24 | 1981-02-11 | Bayer Ag | (2-oxo-imidazoliden-1-yl(carbonylamino)-acetamido-cephalosporins and penicillins |
| KR860000300B1 (en) * | 1983-12-19 | 1986-03-31 | 보령제약 주식회사 | Process for preparing acylureide penicillin derivatives |
-
1971
- 1971-04-23 CH CH599171A patent/CH571524A5/xx not_active IP Right Cessation
- 1971-05-18 BG BG7100017581A patent/BG23753A3/en unknown
- 1971-05-19 CS CS7100003647A patent/CS185564B2/en unknown
- 1971-05-19 EG EG212/71A patent/EG10490A/en active
- 1971-05-20 SU SU1660129A patent/SU420181A3/en active
- 1971-05-21 FI FI1402/71A patent/FI54485C/en active
- 1971-05-21 IE IE644/71A patent/IE35404B1/en unknown
- 1971-05-21 LU LU63204D patent/LU63204A1/xx unknown
- 1971-05-24 IL IL7136904A patent/IL36904A/en unknown
- 1971-05-24 YU YU1296/71A patent/YU35889B/en unknown
- 1971-05-24 SE SE7106668A patent/SE395895B/en unknown
- 1971-05-24 NO NO1946/71A patent/NO141759C/en unknown
- 1971-05-24 PH PH12494A patent/PH12110A/en unknown
- 1971-05-24 DD DD71155308A patent/DD91496B3/en unknown
- 1971-05-24 DK DK251171A patent/DK134438C/en not_active IP Right Cessation
- 1971-05-25 CA CA113785A patent/CA932722A/en not_active Expired
- 1971-05-25 RO RO67015A patent/RO59290A/ro unknown
- 1971-05-25 CY CY830A patent/CY830A/en unknown
- 1971-05-25 NL NLAANVRAGE7107176,A patent/NL172659C/en not_active IP Right Cessation
- 1971-05-25 JP JP3524571A patent/JPS55390B1/ja active Pending
- 1971-05-25 AT AT450571A patent/AT306924B/en not_active IP Right Cessation
- 1971-05-25 FR FR7118933A patent/FR2100682B1/fr not_active Expired
- 1971-05-25 BE BE767648A patent/BE767648A/en not_active IP Right Cessation
- 1971-05-25 GB GB1688171A patent/GB1301962A/en not_active Expired
- 1971-05-25 ES ES391533A patent/ES391533A1/en not_active Expired
-
1973
- 1973-02-16 ES ES411676A patent/ES411676A1/en not_active Expired
- 1973-02-16 ES ES411674A patent/ES411674A1/en not_active Expired
- 1973-02-16 ES ES411675A patent/ES411675A1/en not_active Expired
-
1975
- 1975-12-22 KE KE2591*UA patent/KE2591A/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES438946A2 (en) | Vincaminic acid esters | |
| ES425626A1 (en) | Acylxylidide local anaesthetics | |
| SE7611047L (en) | PROCEDURE FOR PREPARING ANTIBACTERIAL SUBJECT | |
| ES411675A1 (en) | Procedure for obtaining antibacterial compositions. (Machine-translation by Google Translate, not legally binding) | |
| ES403125A1 (en) | Procedure for obtaining an antibacterial composition. (Machine-translation by Google Translate, not legally binding) | |
| ES454085A1 (en) | Procedure for the preparation of N- (r-tetrahydrofurfuril) -noroximorphone and N- (s-tetrahydrofurfuril) -noroximorphone new. (Machine-translation by Google Translate, not legally binding) | |
| GB1451902A (en) | Bromo dihydrolysergic acid | |
| ATE66920T1 (en) | NEW CARBONIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND MEDICATIONS CONTAINING THESE COMPOUNDS. | |
| GB894460A (en) | Improvements in or relating to penicillins | |
| ES412068A1 (en) | Xylidides | |
| GB1488224A (en) | 7alpha-methoxycephalosporin compounds | |
| ES424204A1 (en) | 1-oxadethiapenicillanic acid derivatives | |
| ES367158A1 (en) | Procedure for the preparation of 3-phenyl-imidazo-tiazol. (Machine-translation by Google Translate, not legally binding) | |
| JPS5283393A (en) | Synthesis of novel penicillin derivatives | |
| GB1153973A (en) | alpha,alpha-Diphenyl-beta-Methyl-1-Azaspiro[4,5]Decane (and [4,4]Nonane)-1-Propanols | |
| GB1061566A (en) | Phenoxymethyl penicillins | |
| JPS5278891A (en) | Synthesis of cephalosporin antibiotics | |
| GB1413407A (en) | Dihydropyrido-pyrimidine derivatives their preparation and therapeutical use | |
| ES356225A1 (en) | Procedure for the preparation of diariletilaminas. (Machine-translation by Google Translate, not legally binding) | |
| ES433553A1 (en) | Disbustistuted xanthone carboxylic acid compounds | |
| ES426123A2 (en) | 2-propyl-5-thiazole carboxylates | |
| ES431524A2 (en) | A procedure for preparing ftalazine derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES440479A1 (en) | Procedure for obtaining a penicillin derivative. (Machine-translation by Google Translate, not legally binding) | |
| ES398222A1 (en) | Benzodiazepine derivatives and a process for the manjfacture thereof | |
| ES405281A1 (en) | Cephalosporin compounds |