GB1323383A - Pregna-4,9-diene processes for its preparation and compositions thereof - Google Patents
Pregna-4,9-diene processes for its preparation and compositions thereofInfo
- Publication number
- GB1323383A GB1323383A GB2297071A GB2297071A GB1323383A GB 1323383 A GB1323383 A GB 1323383A GB 2297071 A GB2297071 A GB 2297071A GB 2297071 A GB2297071 A GB 2297071A GB 1323383 A GB1323383 A GB 1323383A
- Authority
- GB
- United Kingdom
- Prior art keywords
- diene
- preparation
- compositions
- pregna
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000002280 anti-androgenic effect Effects 0.000 abstract 1
- 230000001833 anti-estrogenic effect Effects 0.000 abstract 1
- 230000002054 antogonadotrophic effect Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000328 estrogen antagonist Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000962 progestomimetic effect Effects 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1323383 A 13-ethyl-#<SP>4,9</SP> steroid ROUSSELUCLAF 19 April 1971 [3 March 1970] 22970/71 Addition to 1127749 Heading C2U The invention comprises 13#-ethyl-17α- methyl - 18,19 - dinorpregna - 4,9 - diene - 3,20- dione and its preparation by oxidation of the corresponding 20α- or 20#-hydroxy compound or a mixture of these two isomers. The inventive compound is stated to possess antigonadotrophic, antiestrogenic, antiandrogenic and progestomimetic activities, and may be made up with carriers into pharmaceutical compositions for oral, parenteral, topical and rectal administration.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR707007551A FR2081561B1 (en) | 1970-03-03 | 1970-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1323383A true GB1323383A (en) | 1973-07-11 |
Family
ID=9051572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2297071A Expired GB1323383A (en) | 1970-03-03 | 1971-04-19 | Pregna-4,9-diene processes for its preparation and compositions thereof |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5343497B1 (en) |
| AT (1) | AT307636B (en) |
| BE (1) | BE763660A (en) |
| CA (1) | CA934367A (en) |
| CH (1) | CH536829A (en) |
| DE (1) | DE2109853B2 (en) |
| DK (1) | DK124127B (en) |
| ES (1) | ES388783A1 (en) |
| FR (1) | FR2081561B1 (en) |
| GB (1) | GB1323383A (en) |
| IL (1) | IL36214A (en) |
| NL (1) | NL169592C (en) |
| SE (1) | SE368397B (en) |
| ZA (1) | ZA711131B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4692100A (en) * | 1984-02-29 | 1987-09-08 | F.B.M. Hudon Italiana S.p.A. | Vacuum blade for a hollow type fan and process |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007027636A1 (en) * | 2007-06-12 | 2008-12-18 | Bayer Schering Pharma Aktiengesellschaft | 17β-Cyano-18α-homo-19-nor-androst-4-ene derivative, its use and the derivative-containing drug |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1487510A (en) * | 1965-06-01 | 1967-07-07 | Merck & Co Inc | Process for the production of gonenols and substituted gonadienols |
-
1970
- 1970-03-03 FR FR707007551A patent/FR2081561B1/fr not_active Expired
-
1971
- 1971-02-17 IL IL36214A patent/IL36214A/en unknown
- 1971-02-22 ZA ZA711131A patent/ZA711131B/en unknown
- 1971-03-02 AT AT177571A patent/AT307636B/en not_active IP Right Cessation
- 1971-03-02 CH CH302971A patent/CH536829A/en not_active IP Right Cessation
- 1971-03-02 BE BE763660A patent/BE763660A/en not_active IP Right Cessation
- 1971-03-02 CA CA106701A patent/CA934367A/en not_active Expired
- 1971-03-02 NL NLAANVRAGE7102735,A patent/NL169592C/en not_active IP Right Cessation
- 1971-03-02 JP JP1043271A patent/JPS5343497B1/ja active Pending
- 1971-03-02 DK DK95871AA patent/DK124127B/en not_active IP Right Cessation
- 1971-03-02 ES ES388783A patent/ES388783A1/en not_active Expired
- 1971-03-02 SE SE02671/71A patent/SE368397B/xx unknown
- 1971-03-02 DE DE2109853A patent/DE2109853B2/en active Granted
- 1971-04-19 GB GB2297071A patent/GB1323383A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4692100A (en) * | 1984-02-29 | 1987-09-08 | F.B.M. Hudon Italiana S.p.A. | Vacuum blade for a hollow type fan and process |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2109853A1 (en) | 1971-09-23 |
| IL36214A (en) | 1974-09-10 |
| AT307636B (en) | 1973-05-25 |
| DE2109853C3 (en) | 1980-02-21 |
| DK124127B (en) | 1972-09-18 |
| BE763660A (en) | 1971-09-02 |
| ES388783A1 (en) | 1974-02-16 |
| ZA711131B (en) | 1972-03-29 |
| SE368397B (en) | 1974-07-01 |
| FR2081561B1 (en) | 1973-04-06 |
| NL7102735A (en) | 1971-09-07 |
| DE2109853B2 (en) | 1979-06-21 |
| CH536829A (en) | 1973-05-15 |
| JPS5343497B1 (en) | 1978-11-20 |
| FR2081561A1 (en) | 1971-12-10 |
| IL36214A0 (en) | 1971-04-28 |
| CA934367A (en) | 1973-09-25 |
| NL169592C (en) | 1982-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE | Patent expired |