ES385590A1 - Treating immune response with amino purine derivatives - Google Patents

Treating immune response with amino purine derivatives

Info

Publication number
ES385590A1
ES385590A1 ES385590A ES385590A ES385590A1 ES 385590 A1 ES385590 A1 ES 385590A1 ES 385590 A ES385590 A ES 385590A ES 385590 A ES385590 A ES 385590A ES 385590 A1 ES385590 A1 ES 385590A1
Authority
ES
Spain
Prior art keywords
immune response
purine derivatives
amino
treating immune
amino purine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES385590A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of ES385590A1 publication Critical patent/ES385590A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Compounds of the formula WHERE R1 is amino or lower alkylamino, R2 is amino or hydrogen and pharmaceutically acceptable salts thereof, provided that when R1 is amino, R2 is amino. The compounds are useful as immune suppressants and as antivirals.
ES385590A 1969-11-17 1970-11-16 Treating immune response with amino purine derivatives Expired ES385590A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87744369A 1969-11-17 1969-11-17

Publications (1)

Publication Number Publication Date
ES385590A1 true ES385590A1 (en) 1973-10-01

Family

ID=25369972

Family Applications (2)

Application Number Title Priority Date Filing Date
ES385590A Expired ES385590A1 (en) 1969-11-17 1970-11-16 Treating immune response with amino purine derivatives
ES413787A Expired ES413787A1 (en) 1969-11-17 1973-04-16 Treating immune response with amino purine derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES413787A Expired ES413787A1 (en) 1969-11-17 1973-04-16 Treating immune response with amino purine derivatives

Country Status (26)

Country Link
US (1) US3666856A (en)
JP (1) JPS5429520B1 (en)
AT (1) AT309696B (en)
BE (1) BE759011A (en)
BR (1) BR6915136D0 (en)
CA (1) CA967564A (en)
CH (2) CH555833A (en)
CS (1) CS181701B2 (en)
DE (1) DE2056327C2 (en)
DK (1) DK128117B (en)
ES (2) ES385590A1 (en)
FI (1) FI54315C (en)
FR (1) FR2073364B1 (en)
GB (2) GB1338906A (en)
HU (1) HU163812B (en)
IE (1) IE34737B1 (en)
IL (1) IL35658A (en)
LU (1) LU62071A1 (en)
MC (1) MC869A1 (en)
NL (1) NL171589C (en)
NO (1) NO128156B (en)
PL (1) PL81167B1 (en)
SE (1) SE385374B (en)
YU (2) YU35033B (en)
ZA (1) ZA707722B (en)
ZM (1) ZM12970A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4081534A (en) * 1973-09-11 1978-03-28 Burroughs Wellcome Co. Amino purine nucleosides as autoimmune suppressant agents
GB1562899A (en) * 1975-06-17 1980-03-19 Wellcome Found Pharmaceutical compositions containing substituted 9-( -d-arabnofuranosyl)purine-5'-phosphate and salts thereof
US4210745A (en) * 1978-01-04 1980-07-01 The United States Of America As Represented By The Department Of Health, Education And Welfare Procedure for the preparation of 9-β-D-arabinofuranosyl-2-fluoroadenine
DE3319282A1 (en) * 1983-05-27 1984-11-29 Gödecke AG, 1000 Berlin USE OF ADENOSINE IN THE TREATMENT OF HERPES
GB8712745D0 (en) * 1987-05-30 1987-07-01 Wellcome Found Antiviral compounds
ATE128141T1 (en) * 1988-03-16 1995-10-15 Scripps Research Inst SUBSTITUTED ADENINE DERIVATIVES USABLE AS THERAPEUTIC AGENTS.
IE882585L (en) * 1988-08-25 1990-02-25 Prendergast Patrick T Viral treatment system
US5292725A (en) * 1988-08-25 1994-03-08 Prendergast Patrick T Administering particular compounds against various parasites, mycoplasmas, other indications and other infections
US5681941A (en) * 1990-01-11 1997-10-28 Isis Pharmaceuticals, Inc. Substituted purines and oligonucleotide cross-linking
US5308837A (en) * 1990-08-22 1994-05-03 Merrell Dow Pharmaceuticals Inc. 5'-amine substituted adenosine analogs as immunosuppressants
US6338963B1 (en) 1994-07-25 2002-01-15 Neotherapeutics, Inc. Use of carbon monoxide dependent guanylyl cyclase modifiers to stimulate neuritogenesis
US6232463B1 (en) 1997-10-09 2001-05-15 Isis Pharmaceuticals, Inc. Substituted purines and oligonucleotide cross-linking
WO1999057120A1 (en) 1998-05-04 1999-11-11 Neotherapeutics, Inc. Novel serotonin-like 9-substituted hypoxanthine and methods of use
US6288069B1 (en) 1999-11-16 2001-09-11 Neotherapeutics, Inc. Use of 9-substituted hypoxanthine derivatives to stimulate regeneration of nervous tissue
US6407237B1 (en) 2001-02-21 2002-06-18 Neotherapeutics, Inc. Crystal forms of 9-substituted hypoxanthine derivatives
US6849735B1 (en) 2000-06-23 2005-02-01 Merck Eprova Ag Methods of synthesis for 9-substituted hypoxanthine derivatives
ATE499103T1 (en) 2000-07-07 2011-03-15 Spectrum Pharmaceuticals Inc METHOD FOR TREATING DRUG-INDUCED PERIPHERAL NEUROPATHY AND RELATED MEDIA
US6759427B2 (en) * 2001-04-20 2004-07-06 Spectrum Pharmaceuticals, Inc. Synthesis and methods of use of tetrahydroindolone analogues and derivatives
US20030055249A1 (en) * 2001-07-17 2003-03-20 Fick David B. Synthesis and methods of use of pyrimidine analogues and derivatives
CN105237602B (en) * 2015-06-25 2018-05-18 新乡学院 A kind of preparation method of 2- amino arabinosy ladenosine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3208997A (en) * 1962-11-15 1965-09-28 Sankyo Co Process for preparing purine and pyrimidine nucleosides
US3407191A (en) * 1966-08-29 1968-10-22 Lilly Co Eli Adamantoate esters of nucleosides
JPH1097965A (en) * 1996-09-20 1998-04-14 Sony Corp Production control method

Also Published As

Publication number Publication date
FR2073364B1 (en) 1974-03-22
HU163812B (en) 1973-10-27
ZA707722B (en) 1972-06-28
YU280670A (en) 1979-12-31
FR2073364A1 (en) 1971-10-01
BE759011A (en) 1971-05-17
DE2056327C2 (en) 1984-10-11
SE385374B (en) 1976-06-28
DE2056327A1 (en) 1971-06-03
YU35034B (en) 1980-06-30
ES413787A1 (en) 1976-01-16
YU201978A (en) 1979-12-31
DK128117B (en) 1974-03-04
NL171589C (en) 1983-04-18
MC869A1 (en) 1971-09-28
IL35658A0 (en) 1971-01-28
ZM12970A1 (en) 1972-07-21
YU35033B (en) 1980-06-30
NL171589B (en) 1982-11-16
CS181701B2 (en) 1978-03-31
LU62071A1 (en) 1971-08-12
IE34737B1 (en) 1975-08-06
US3666856A (en) 1972-05-30
AT309696B (en) 1973-08-27
NL7016766A (en) 1971-05-19
CH555833A (en) 1974-11-15
IL35658A (en) 1974-10-22
GB1338906A (en) 1973-11-28
CA967564A (en) 1975-05-13
NO128156B (en) 1973-10-08
JPS5429520B1 (en) 1979-09-25
PL81167B1 (en) 1975-08-30
IE34737L (en) 1971-05-17
CH555344A (en) 1974-10-31
FI54315C (en) 1978-11-10
GB1338905A (en) 1973-11-28
FI54315B (en) 1978-07-31
BR6915136D0 (en) 1973-04-19

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