ES302198A1 - Improvements in and relating to the preparation of substituted carbinols - Google Patents

Improvements in and relating to the preparation of substituted carbinols

Info

Publication number
ES302198A1
ES302198A1 ES0302198A ES302198A ES302198A1 ES 302198 A1 ES302198 A1 ES 302198A1 ES 0302198 A ES0302198 A ES 0302198A ES 302198 A ES302198 A ES 302198A ES 302198 A1 ES302198 A1 ES 302198A1
Authority
ES
Spain
Prior art keywords
thienyl
prepared
liberating
tetrahydrofuran
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0302198A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PROD CHIM ET DE SYNTHESE SOC D
Original Assignee
PROD CHIM ET DE SYNTHESE SOC D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PROD CHIM ET DE SYNTHESE SOC D filed Critical PROD CHIM ET DE SYNTHESE SOC D
Publication of ES302198A1 publication Critical patent/ES302198A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Compounds of the general formula <FORM:1062877/C2/1> (in which R1 and R2 represent alkyl radicals or, together with the nitrogen atom, form a monocyclic, saturated heterocyclic ring) are prepared by liberating the corresponding aminoalkyl a -thienyl ketone from an acid addition salt thereof by treatment with calcium hydroxide in the presence of an aromatic solvent having a boiling point between 100 DEG and 200 DEG C., reacting the resulting solution with a phenyl magnesium halide prepared in tetrahydrofuran, removing the tetrahydrofuran from the reaction mixture and liberating the product from its magnesium complex. 1 - (a - Thienyl) - 1 - phenyl - 3 - piperidino - 1 - propanol is characterized as the picrate, and 1 - (a - thienyl) - 3 - dimethylamino - 1 - propanone hydrochloride is prepared by the Mannich reaction.
ES0302198A 1963-08-30 1964-07-17 Improvements in and relating to the preparation of substituted carbinols Expired ES302198A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR946086A FR1496714A (en) 1963-08-30 1963-08-30 Improved process for obtaining alpha-thienyl 1-phenyl 1-carbinols

Publications (1)

Publication Number Publication Date
ES302198A1 true ES302198A1 (en) 1965-01-01

Family

ID=8811433

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0302198A Expired ES302198A1 (en) 1963-08-30 1964-07-17 Improvements in and relating to the preparation of substituted carbinols

Country Status (7)

Country Link
BE (1) BE638151A (en)
CH (1) CH415680A (en)
DE (1) DE1470264C3 (en)
ES (1) ES302198A1 (en)
FR (1) FR1496714A (en)
GB (1) GB1062877A (en)
NL (2) NL129015C (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1597591A (en) 1977-01-12 1981-09-09 Degussa Dithienyl alkylamines and alkenylamines and a process for their production

Also Published As

Publication number Publication date
DE1470264B2 (en) 1975-04-24
NL302769A (en)
GB1062877A (en) 1967-03-22
FR1496714A (en) 1967-10-06
CH415680A (en) 1966-06-30
DE1470264A1 (en) 1969-09-18
DE1470264C3 (en) 1975-12-04
NL129015C (en)
BE638151A (en)

Similar Documents

Publication Publication Date Title
ES456279A1 (en) 16,17,18,19,20-pentanorprostaglandins
ES302198A1 (en) Improvements in and relating to the preparation of substituted carbinols
ES380355A1 (en) Process for the preparation of 4-pyrazolidinols
ES274329A1 (en) Procedure for the preparation of new compounds of 1,5-benzodioxepano (Machine-translation by Google Translate, not legally binding)
ES323157A1 (en) A procedure for the preparation of omega-laurino-lactama, to start ciclododecanona. (Machine-translation by Google Translate, not legally binding)
ES274332A1 (en) Preparation of derivatives of 1, 4-benzodioxan
ES277057A1 (en) Procedure for the production of new derivatives of tiaxanthene (Machine-translation by Google Translate, not legally binding)
ES285855A1 (en) A procedure for the manufacture of benzodiazepinic derivatives (Machine-translation by Google Translate, not legally binding)
ES278128A2 (en) Procedure for the preparation of heterocyclic compounds replaced with a base (Machine-translation by Google Translate, not legally binding)
ES272079A1 (en) Procedure for the production of heterocyclic compounds (Machine-translation by Google Translate, not legally binding)
ES292760A2 (en) Procedure for obtaining derivatives of 4-aza-tia-xanteno (Machine-translation by Google Translate, not legally binding)
ES292359A1 (en) Procedure for the production of new heterocyclic compounds and their acid addiction salts (Machine-translation by Google Translate, not legally binding)
ES266946A1 (en) Procedure for obtaining new derivatives of 2,6-dialkilbenzoic acid (Machine-translation by Google Translate, not legally binding)
GR27795B (en) METHOD FOR THE PREPARATION OF NEW HETEROCYCLIC COMPOUNDS.
ES405106A1 (en) Substituted pyrrolidines
ES240535A1 (en) Procedure for the production of compounds ciclohexilamina (Machine-translation by Google Translate, not legally binding)
ES240534A1 (en) Procedure for the production of cyclhexilamine compounds. (Machine-translation by Google Translate, not legally binding)
ES229980A1 (en) Procedure for the manufacture of a therapeutic substance (Machine-translation by Google Translate, not legally binding)
GB926624A (en) New amines and process for their manufacture
ES308607A1 (en) A procedure for the preparation of a compound of 2-alcohylthyrophene. (Machine-translation by Google Translate, not legally binding)
ES240529A1 (en) A new procedure for the production of new heterocyclic compounds. (Machine-translation by Google Translate, not legally binding)
ES240531A1 (en) A new procedure for the production of new heterocyclic compounds. (Machine-translation by Google Translate, not legally binding)
ES240642A1 (en) Procedure to obtain new organic compounds (Machine-translation by Google Translate, not legally binding)
ES421874A1 (en) A procedure for the production of 3-benzazocine compound. (Machine-translation by Google Translate, not legally binding)
ES325350A1 (en) Procedure for the dichloroacetilation of aminoalcoholes. (Machine-translation by Google Translate, not legally binding)