ES302198A1 - Improvements in and relating to the preparation of substituted carbinols - Google Patents
Improvements in and relating to the preparation of substituted carbinolsInfo
- Publication number
- ES302198A1 ES302198A1 ES0302198A ES302198A ES302198A1 ES 302198 A1 ES302198 A1 ES 302198A1 ES 0302198 A ES0302198 A ES 0302198A ES 302198 A ES302198 A ES 302198A ES 302198 A1 ES302198 A1 ES 302198A1
- Authority
- ES
- Spain
- Prior art keywords
- thienyl
- prepared
- liberating
- tetrahydrofuran
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Compounds of the general formula <FORM:1062877/C2/1> (in which R1 and R2 represent alkyl radicals or, together with the nitrogen atom, form a monocyclic, saturated heterocyclic ring) are prepared by liberating the corresponding aminoalkyl a -thienyl ketone from an acid addition salt thereof by treatment with calcium hydroxide in the presence of an aromatic solvent having a boiling point between 100 DEG and 200 DEG C., reacting the resulting solution with a phenyl magnesium halide prepared in tetrahydrofuran, removing the tetrahydrofuran from the reaction mixture and liberating the product from its magnesium complex. 1 - (a - Thienyl) - 1 - phenyl - 3 - piperidino - 1 - propanol is characterized as the picrate, and 1 - (a - thienyl) - 3 - dimethylamino - 1 - propanone hydrochloride is prepared by the Mannich reaction.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR946086A FR1496714A (en) | 1963-08-30 | 1963-08-30 | Improved process for obtaining alpha-thienyl 1-phenyl 1-carbinols |
Publications (1)
Publication Number | Publication Date |
---|---|
ES302198A1 true ES302198A1 (en) | 1965-01-01 |
Family
ID=8811433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0302198A Expired ES302198A1 (en) | 1963-08-30 | 1964-07-17 | Improvements in and relating to the preparation of substituted carbinols |
Country Status (7)
Country | Link |
---|---|
BE (1) | BE638151A (en) |
CH (1) | CH415680A (en) |
DE (1) | DE1470264C3 (en) |
ES (1) | ES302198A1 (en) |
FR (1) | FR1496714A (en) |
GB (1) | GB1062877A (en) |
NL (2) | NL129015C (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1597591A (en) | 1977-01-12 | 1981-09-09 | Degussa | Dithienyl alkylamines and alkenylamines and a process for their production |
-
0
- NL NL302769D patent/NL302769A/xx unknown
- NL NL129015D patent/NL129015C/xx active
- BE BE638151D patent/BE638151A/xx unknown
-
1963
- 1963-08-30 FR FR946086A patent/FR1496714A/en not_active Expired
- 1963-12-18 CH CH1550063A patent/CH415680A/en unknown
- 1963-12-20 GB GB5045763A patent/GB1062877A/en not_active Expired
- 1963-12-24 DE DE19631470264 patent/DE1470264C3/en not_active Expired
-
1964
- 1964-07-17 ES ES0302198A patent/ES302198A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE1470264B2 (en) | 1975-04-24 |
NL302769A (en) | |
GB1062877A (en) | 1967-03-22 |
FR1496714A (en) | 1967-10-06 |
CH415680A (en) | 1966-06-30 |
DE1470264A1 (en) | 1969-09-18 |
DE1470264C3 (en) | 1975-12-04 |
NL129015C (en) | |
BE638151A (en) |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES456279A1 (en) | 16,17,18,19,20-pentanorprostaglandins | |
ES302198A1 (en) | Improvements in and relating to the preparation of substituted carbinols | |
ES380355A1 (en) | Process for the preparation of 4-pyrazolidinols | |
ES274329A1 (en) | Procedure for the preparation of new compounds of 1,5-benzodioxepano (Machine-translation by Google Translate, not legally binding) | |
ES323157A1 (en) | A procedure for the preparation of omega-laurino-lactama, to start ciclododecanona. (Machine-translation by Google Translate, not legally binding) | |
ES274332A1 (en) | Preparation of derivatives of 1, 4-benzodioxan | |
ES277057A1 (en) | Procedure for the production of new derivatives of tiaxanthene (Machine-translation by Google Translate, not legally binding) | |
ES285855A1 (en) | A procedure for the manufacture of benzodiazepinic derivatives (Machine-translation by Google Translate, not legally binding) | |
ES278128A2 (en) | Procedure for the preparation of heterocyclic compounds replaced with a base (Machine-translation by Google Translate, not legally binding) | |
ES272079A1 (en) | Procedure for the production of heterocyclic compounds (Machine-translation by Google Translate, not legally binding) | |
ES292760A2 (en) | Procedure for obtaining derivatives of 4-aza-tia-xanteno (Machine-translation by Google Translate, not legally binding) | |
ES292359A1 (en) | Procedure for the production of new heterocyclic compounds and their acid addiction salts (Machine-translation by Google Translate, not legally binding) | |
ES266946A1 (en) | Procedure for obtaining new derivatives of 2,6-dialkilbenzoic acid (Machine-translation by Google Translate, not legally binding) | |
GR27795B (en) | METHOD FOR THE PREPARATION OF NEW HETEROCYCLIC COMPOUNDS. | |
ES405106A1 (en) | Substituted pyrrolidines | |
ES240535A1 (en) | Procedure for the production of compounds ciclohexilamina (Machine-translation by Google Translate, not legally binding) | |
ES240534A1 (en) | Procedure for the production of cyclhexilamine compounds. (Machine-translation by Google Translate, not legally binding) | |
ES229980A1 (en) | Procedure for the manufacture of a therapeutic substance (Machine-translation by Google Translate, not legally binding) | |
GB926624A (en) | New amines and process for their manufacture | |
ES308607A1 (en) | A procedure for the preparation of a compound of 2-alcohylthyrophene. (Machine-translation by Google Translate, not legally binding) | |
ES240529A1 (en) | A new procedure for the production of new heterocyclic compounds. (Machine-translation by Google Translate, not legally binding) | |
ES240531A1 (en) | A new procedure for the production of new heterocyclic compounds. (Machine-translation by Google Translate, not legally binding) | |
ES240642A1 (en) | Procedure to obtain new organic compounds (Machine-translation by Google Translate, not legally binding) | |
ES421874A1 (en) | A procedure for the production of 3-benzazocine compound. (Machine-translation by Google Translate, not legally binding) | |
ES325350A1 (en) | Procedure for the dichloroacetilation of aminoalcoholes. (Machine-translation by Google Translate, not legally binding) |