ES2777200T8 - Procedimiento para la preparación de 3-aminopiperidina enriquecida enantioméricamente - Google Patents
Procedimiento para la preparación de 3-aminopiperidina enriquecida enantioméricamenteInfo
- Publication number
- ES2777200T8 ES2777200T8 ES14705501T ES14705501T ES2777200T8 ES 2777200 T8 ES2777200 T8 ES 2777200T8 ES 14705501 T ES14705501 T ES 14705501T ES 14705501 T ES14705501 T ES 14705501T ES 2777200 T8 ES2777200 T8 ES 2777200T8
- Authority
- ES
- Spain
- Prior art keywords
- aminopiperidine
- procedure
- preparation
- enantiomerically enriched
- enantiomerically
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13156030 | 2013-02-20 | ||
| PCT/EP2014/053176 WO2014128139A1 (en) | 2013-02-20 | 2014-02-19 | Process for the preparation of enantiomerically enriched 3-aminopiperidine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2777200T3 ES2777200T3 (es) | 2020-08-04 |
| ES2777200T8 true ES2777200T8 (es) | 2020-09-29 |
Family
ID=47748496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14705501T Active ES2777200T3 (es) | 2013-02-20 | 2014-02-19 | Procedimiento para la preparación de 3-aminopiperidina enriquecida enantioméricamente |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10464898B2 (es) |
| EP (3) | EP3653607B1 (es) |
| JP (2) | JP6370316B2 (es) |
| KR (1) | KR102236806B1 (es) |
| CN (1) | CN105102430A (es) |
| DK (1) | DK2958894T3 (es) |
| ES (1) | ES2777200T3 (es) |
| HR (1) | HRP20200437T1 (es) |
| HU (1) | HUE048567T2 (es) |
| IL (1) | IL240214B (es) |
| PL (1) | PL2958894T3 (es) |
| PT (1) | PT2958894T (es) |
| SI (1) | SI2958894T1 (es) |
| WO (1) | WO2014128139A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2958894T3 (pl) | 2013-02-20 | 2020-06-29 | Reuter Chemische Apparatebau E.K. | Sposób wytwarzania enancjomerycznie wzbogaconej 3-aminopiperydyny |
| CN108693272B (zh) * | 2018-06-04 | 2021-03-12 | 吉林百纯化学科技有限公司 | 一种hplc法分析及制备n-（对甲苯磺酰基）-l-丙氨酸及其对映异构体的方法 |
| CN109668987A (zh) * | 2019-02-27 | 2019-04-23 | 浙江华贝药业有限责任公司 | 一种3-氨基哌啶二盐酸盐对映异构体测定分析方法 |
| CN110078657A (zh) * | 2019-04-10 | 2019-08-02 | 湖州复华春生物医药科技有限公司 | 一种手性3-氨基哌啶及其衍生物的合成方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1024974B (de) | 1956-10-17 | 1958-02-27 | Dr Alfred Dornow | Verfahren zur Herstellung von 2-Oxy-7-aza-benzimidazolen |
| US5334766A (en) * | 1991-04-29 | 1994-08-02 | Hoffmann-La Roche Inc. | Process for the resolution of racemic diphosphine oxides |
| US5220016A (en) | 1991-07-29 | 1993-06-15 | Board Of Regents, The University Of Texas System | Synthesis of navelbine analogs |
| JP3716376B2 (ja) * | 1995-10-26 | 2005-11-16 | 東レ・ファインケミカル株式会社 | 光学分割剤およびそれを用いた光学活性３−アミノピロリジン誘導体の製造法 |
| DK0956122T3 (da) | 1996-03-10 | 2002-11-18 | Reuter Chemischer Appbau Kg | Separationsproces |
| EP1165543B1 (en) | 1999-03-22 | 2003-06-04 | Ortho-Mcneil Pharmaceutical, Inc. | PROCESS FOR PREPARING S-(R*,S*)] -$g(b) - 1- 1-OXO-3- (4-PIPERIDINYL) PROPYL] -3-PIPERIDINYL] CARBONYL] AMINO] -3- PYRIDINEPROPANOIC ACID AND DERIVATIVES |
| AU781747B2 (en) * | 1999-10-08 | 2005-06-09 | Meiji Seika Kaisha Ltd. | 3-aminopiperidine derivatives as integrin alphavbeta3 antagonists |
| WO2001068604A2 (en) | 2000-03-14 | 2001-09-20 | Sepracor, Inc. | 3-substituted piperidines comprising urea functionality, and methods of use thereof |
| EP1146029A1 (en) | 2000-04-13 | 2001-10-17 | Nissan Chemical Industries Ltd. | Method for optical resolution of piperidine carboxylic acid derivative |
| EP1341762A1 (en) | 2000-11-20 | 2003-09-10 | Eli Lilly And Company | Process for resolving racemic mixtures of piperidine derivatives |
| GB0126859D0 (en) | 2001-11-08 | 2002-01-02 | Kee Klamp Ltd | Counter-balance weight for a modular safety rail |
| WO2007075630A1 (en) | 2005-12-22 | 2007-07-05 | Dow Global Technologies Inc. | Method for producing 3-aminopiperidine diastereomer |
| ITMI20060179A1 (it) * | 2006-02-02 | 2007-08-03 | Abiogen Pharma Spa | Procedimento per la risoluzione di miscele racemiche e complesso diastereoisomerico di un agente risolvente e di unantiomero di interesse |
| EP1999108A1 (en) * | 2006-03-28 | 2008-12-10 | Takeda Pharmaceutical Company Limited | Preparation of (r)-3-aminopiperidine dihydrochloride |
| JP5265513B2 (ja) * | 2007-02-19 | 2013-08-14 | 株式会社カネカ | 光学活性３−アミノピペリジン又はその塩の製造方法 |
| WO2009107571A1 (ja) * | 2008-02-27 | 2009-09-03 | 住友化学株式会社 | アルキルピペリジン－３－イルカーバメートの光学分割方法およびその中間体 |
| CN101565397B (zh) * | 2009-04-07 | 2011-08-10 | 浙江医药股份有限公司新昌制药厂 | N-Boc-3-氨基哌啶及其光学异构体的合成方法 |
| JP2011012032A (ja) | 2009-07-03 | 2011-01-20 | Yamakawa Yakuhin Kogyo Kk | 光学活性な３−アミノピペリジンの製造方法および製造の中間体 |
| JP5585822B2 (ja) | 2010-05-11 | 2014-09-10 | 東レ・ファインケミカル株式会社 | 光学活性ニペコチン酸誘導体の製造方法 |
| WO2011160037A2 (en) * | 2010-06-17 | 2011-12-22 | Dr. Reddy's Laboratories Ltd. | Process for the preparation of a single enantiomer of 3-aminopiperidine dihydrochloride |
| PL2958894T3 (pl) | 2013-02-20 | 2020-06-29 | Reuter Chemische Apparatebau E.K. | Sposób wytwarzania enancjomerycznie wzbogaconej 3-aminopiperydyny |
-
2014
- 2014-02-19 PL PL14705501T patent/PL2958894T3/pl unknown
- 2014-02-19 SI SI201431527T patent/SI2958894T1/sl unknown
- 2014-02-19 EP EP19214799.9A patent/EP3653607B1/en active Active
- 2014-02-19 EP EP23204103.8A patent/EP4289819A3/en active Pending
- 2014-02-19 CN CN201480009307.6A patent/CN105102430A/zh active Pending
- 2014-02-19 PT PT147055016T patent/PT2958894T/pt unknown
- 2014-02-19 EP EP14705501.6A patent/EP2958894B8/en active Active
- 2014-02-19 ES ES14705501T patent/ES2777200T3/es active Active
- 2014-02-19 KR KR1020157025543A patent/KR102236806B1/ko active IP Right Grant
- 2014-02-19 JP JP2015557468A patent/JP6370316B2/ja active Active
- 2014-02-19 WO PCT/EP2014/053176 patent/WO2014128139A1/en active Application Filing
- 2014-02-19 HU HUE14705501A patent/HUE048567T2/hu unknown
- 2014-02-19 DK DK14705501.6T patent/DK2958894T3/da active
- 2014-02-19 US US14/768,751 patent/US10464898B2/en active Active
-
2015
- 2015-07-29 IL IL240214A patent/IL240214B/en active IP Right Grant
-
2018
- 2018-07-10 JP JP2018130513A patent/JP6580218B2/ja active Active
-
2019
- 2019-09-23 US US16/579,584 patent/US11472770B2/en active Active
-
2020
- 2020-03-17 HR HRP20200437TT patent/HRP20200437T1/hr unknown
-
2022
- 2022-09-09 US US17/941,959 patent/US11897843B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014128139A1 (en) | 2014-08-28 |
| HRP20200437T1 (hr) | 2020-09-04 |
| PT2958894T (pt) | 2020-03-10 |
| JP6580218B2 (ja) | 2019-09-25 |
| IL240214B (en) | 2018-02-28 |
| US20230008387A1 (en) | 2023-01-12 |
| JP6370316B2 (ja) | 2018-08-08 |
| JP2016508514A (ja) | 2016-03-22 |
| ES2777200T3 (es) | 2020-08-04 |
| PL2958894T3 (pl) | 2020-06-29 |
| EP4289819A3 (en) | 2024-01-10 |
| US20160251311A1 (en) | 2016-09-01 |
| CN105102430A (zh) | 2015-11-25 |
| EP2958894B1 (en) | 2019-12-18 |
| US11897843B2 (en) | 2024-02-13 |
| EP3653607C0 (en) | 2023-10-18 |
| JP2018168194A (ja) | 2018-11-01 |
| IL240214A0 (en) | 2015-09-24 |
| EP3653607A2 (en) | 2020-05-20 |
| EP2958894B8 (en) | 2020-02-26 |
| EP3653607A3 (en) | 2020-07-29 |
| DK2958894T3 (da) | 2020-03-23 |
| KR20150123267A (ko) | 2015-11-03 |
| KR102236806B1 (ko) | 2021-04-06 |
| US10464898B2 (en) | 2019-11-05 |
| HUE048567T2 (hu) | 2020-07-28 |
| SI2958894T1 (sl) | 2020-07-31 |
| EP2958894A1 (en) | 2015-12-30 |
| EP3653607B1 (en) | 2023-10-18 |
| US20200087257A1 (en) | 2020-03-19 |
| EP4289819A2 (en) | 2023-12-13 |
| US11472770B2 (en) | 2022-10-18 |
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