ES2565629T3 - Comprimido de adhesión oral bicapa con adhesivo de goma arábiga - Google Patents

Comprimido de adhesión oral bicapa con adhesivo de goma arábiga Download PDF

Info

Publication number
ES2565629T3
ES2565629T3 ES12155514.8T ES12155514T ES2565629T3 ES 2565629 T3 ES2565629 T3 ES 2565629T3 ES 12155514 T ES12155514 T ES 12155514T ES 2565629 T3 ES2565629 T3 ES 2565629T3
Authority
ES
Spain
Prior art keywords
gum arabic
adhesion tablet
bilayer oral
oral adhesion
adhesive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12155514.8T
Other languages
English (en)
Inventor
Jeffrey T. Haley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orahealth LLC
Original Assignee
Orahealth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orahealth LLC filed Critical Orahealth LLC
Application granted granted Critical
Publication of ES2565629T3 publication Critical patent/ES2565629T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un comprimido adhesivo oral bicapa redondeado, que tiene forma plana con una anchura mayor de 5 mm y un espesor menor que la anchura, en donde una primera capa, que incluye un lado del espesor, es una capa adherente y comprende, en peso seco, al menos el 80% de goma arábiga.

Description

imagen1
imagen2
imagen3
imagen4

Claims (1)

  1. imagen1
ES12155514.8T 2006-05-23 2007-05-04 Comprimido de adhesión oral bicapa con adhesivo de goma arábiga Active ES2565629T3 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US80803506P 2006-05-23 2006-05-23
US808035P 2006-05-23
US87984607P 2007-01-11 2007-01-11
US879846P 2007-01-11
US88759507P 2007-02-22 2007-02-22
US887595P 2007-02-22

Publications (1)

Publication Number Publication Date
ES2565629T3 true ES2565629T3 (es) 2016-04-06

Family

ID=38778968

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12155514.8T Active ES2565629T3 (es) 2006-05-23 2007-05-04 Comprimido de adhesión oral bicapa con adhesivo de goma arábiga

Country Status (8)

Country Link
US (1) US8865133B2 (es)
EP (2) EP2462926B1 (es)
JP (1) JP5410964B2 (es)
KR (1) KR101474871B1 (es)
CN (1) CN102582106B (es)
AU (1) AU2007268240B2 (es)
ES (1) ES2565629T3 (es)
WO (1) WO2007139661A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012527455A (ja) * 2009-05-18 2012-11-08 コルゲート・パーモリブ・カンパニー 口腔用組成物
US12016950B2 (en) 2010-09-01 2024-06-25 Try This First, Inc. Devices and methods for treating ear pain
WO2012031123A2 (en) 2010-09-01 2012-03-08 Trythisfirst, Inc. Method of treating ear infections
RU2631485C2 (ru) * 2012-02-19 2017-09-22 Орахэлс Корпорейшн Клейкое вещество на основе гуммиарабика, смешанное с карбонатом кальция, для пероральных прилипающих дисков
GB201303781D0 (en) 2013-03-04 2013-04-17 Gauthier Pierre Pascal Oral timer device and method of using same
US20140335139A1 (en) * 2013-05-13 2014-11-13 NeuOra Microceuticals, LLC Long lasting breath mint
EP3030228B1 (en) * 2013-08-08 2020-09-02 Quest Products, LLC Reducing reflux while sleeping by stimulating saliva with adhering troches
JP6615978B2 (ja) * 2016-02-25 2019-12-04 久光製薬株式会社 口腔内貼付剤
US11612564B2 (en) 2018-04-21 2023-03-28 Quest Products, Llc Bilayer adhering lozenge effective to mask undesirable flavor
US11116096B2 (en) 2019-04-18 2021-09-07 City University Of Hong Kong Medium for binding components in an assembly of an electronic device, a method of preparing the same, a display assembly of an electronic device, and a system for simulating mechanical behaviours of the electronic device and the medium

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5138412A (en) 1974-09-24 1976-03-31 Nippon Kayaku Kk Kokoseizai no seiho
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
JP2573969B2 (ja) * 1987-10-21 1997-01-22 帝國製薬株式会社 薬物断続放出性口腔内適用製剤
US5236713A (en) 1987-10-21 1993-08-17 Teikoku Seiyaku Kabushiki Kaisha Preparation for intermittently releasing active agent applicable to oral cavity
JPH0669948B2 (ja) * 1989-07-21 1994-09-07 エスエス製薬株式会社 トローチ剤
US5380530A (en) * 1992-12-29 1995-01-10 Whitehill Oral Technologies Oral care composition coated gum
US5330761A (en) 1993-01-29 1994-07-19 Edward Mendell Co. Inc. Bioadhesive tablet for non-systemic use products
US5578315A (en) 1993-12-01 1996-11-26 Rutgers, The State University Of New Jersey Mucosal adhesive device for long-acting delivery of pharmaceutical combinations in oral cavity
CA2184316A1 (en) * 1995-09-12 1997-03-13 Wei-Chi Liao Buccal delivery system for therapeutic agents
US5849322A (en) * 1995-10-23 1998-12-15 Theratech, Inc. Compositions and methods for buccal delivery of pharmaceutical agents
NZ325844A (en) 1995-12-27 1999-06-29 Janssen Pharmaceutica Nv A bioadhesive tablet comprising a c16-c22alkyl fumarate as lubricant
IT1282576B1 (it) * 1996-02-06 1998-03-31 Jagotec Ag Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili
US5800832A (en) * 1996-10-18 1998-09-01 Virotex Corporation Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces
IT1297233B1 (it) * 1996-10-29 1999-08-09 Montefarmaco Spa Composizioni farmaceutiche solide in forma di caramelle contenenti disinfettanti e sostanze mucoadesive per una disinfezione topica
JPH10206963A (ja) * 1996-11-21 1998-08-07 Olympus Optical Co Ltd 電子撮像表示可能な銀塩フィルム用カメラ
FR2762513B1 (fr) * 1997-04-23 2003-08-22 Permatec Pharma Ag Comprimes bioadhesifs
US6210710B1 (en) * 1997-04-28 2001-04-03 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
US6365185B1 (en) * 1998-03-26 2002-04-02 University Of Cincinnati Self-destructing, controlled release peroral drug delivery system
JP2000063268A (ja) * 1998-06-12 2000-02-29 Lion Corp 口腔粘膜付着型徐放性錠剤及び歯周疾患治療剤
SE9803240D0 (sv) * 1998-09-24 1998-09-24 Diabact Ab A pharmaceutical composition having a rapid action
FR2786407B1 (fr) * 1998-11-27 2001-02-16 Roquette Freres Composition de polyols concentree
JP2000178185A (ja) * 1998-12-18 2000-06-27 Lion Corp 口腔粘膜付着型徐放性錠剤
US6139861A (en) 1999-01-14 2000-10-31 Friedman; Mark Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache facial pain, and cervical-muscle spasm
US6706283B1 (en) * 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
US6210699B1 (en) 1999-04-01 2001-04-03 Watson Pharmaceuticals, Inc. Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity
JP2001002590A (ja) * 1999-06-21 2001-01-09 Lion Corp 口腔粘膜付着型徐放性錠剤
AU2001273545A1 (en) * 2000-07-19 2002-01-30 Lavipharm Laboratories, Inc. Sildenafil citrate solid dispersions having high water solubility
DE10038571A1 (de) * 2000-08-03 2002-02-14 Knoll Ag Zusammensetzungen und Dosierungsformen zur Anwendung in der Mundhöhle bei der Bhandlung von Mykosen
EP1236466B1 (en) * 2001-02-28 2011-09-21 Axiomedic Ltd. Solid self-adhesive compositions for topical treatment of oral mucosal disorders
US6455512B1 (en) * 2001-03-05 2002-09-24 Tic Gums, Inc. Water-soluble esterified hydrocolloids
GB0117618D0 (en) * 2001-07-19 2001-09-12 Phoqus Ltd Pharmaceutical dosage form
US6830442B2 (en) * 2001-08-09 2004-12-14 William Alvin Cecil Rotary tablet press
WO2003018302A1 (fr) * 2001-08-30 2003-03-06 Sanwa Kagaku Kenkyusho Co., Ltd Dispositif de fabrication d'articles moules et article moule pouvant etre fabrique par ce dispositif
CN1638740A (zh) * 2001-09-28 2005-07-13 麦克内尔-Ppc股份有限公司 释出得到修饰的剂型
US6723304B2 (en) 2001-11-13 2004-04-20 Noville, Inc. Oral care compositions comprising diglycerol
US20030175360A1 (en) * 2002-02-22 2003-09-18 Renzo Luzzatti Symptomatic relief of gastrointestinal disorders
WO2003086297A2 (en) * 2002-04-08 2003-10-23 Lavipharm Laboratories, Inc. Multi-layer mucoadhesive drug delivery device with bursting release layer
CN1747722A (zh) * 2003-02-04 2006-03-15 赛福伦公司 无糖经口腔粘膜的固态剂型及其应用
US20040253307A1 (en) * 2003-02-04 2004-12-16 Brian Hague Sugar-free oral transmucosal solid dosage forms and uses thereof
US20040241223A1 (en) * 2003-05-27 2004-12-02 David Wong Oral dosage forms for macromolecular drugs
FR2855756B1 (fr) * 2003-06-06 2005-08-26 Ethypharm Sa Comprime orodispersible multicouche
GB0320854D0 (en) * 2003-09-05 2003-10-08 Arrow No 7 Ltd Buccal drug delivery
WO2005105036A1 (en) * 2004-04-28 2005-11-10 Natco Pharma Limited Controlled release mucoadhesive matrix formulation containing tolterodine and a process for its preparation
US20060093560A1 (en) * 2004-10-29 2006-05-04 Jen-Chi Chen Immediate release film coating
US20060193909A1 (en) * 2005-02-07 2006-08-31 Stawski Barbara Z Breath freshening pressed tablets and methods of making and using same
US20070048369A1 (en) 2005-08-26 2007-03-01 National Starch And Chemical Investment Holding Corporation Mucosal delivery tablet

Also Published As

Publication number Publication date
WO2007139661A1 (en) 2007-12-06
EP2037895A1 (en) 2009-03-25
KR101474871B1 (ko) 2014-12-19
CN102582106B (zh) 2015-12-16
JP2009538301A (ja) 2009-11-05
JP5410964B2 (ja) 2014-02-05
AU2007268240A1 (en) 2007-12-06
EP2462926A1 (en) 2012-06-13
US20070274927A1 (en) 2007-11-29
CN102582106A (zh) 2012-07-18
KR20090086025A (ko) 2009-08-10
EP2462926B1 (en) 2015-12-30
AU2007268240B2 (en) 2012-12-06
EP2037895A4 (en) 2009-12-02
US8865133B2 (en) 2014-10-21

Similar Documents

Publication Publication Date Title
ES2565629T3 (es) Comprimido de adhesión oral bicapa con adhesivo de goma arábiga
ES2548100T3 (es) Película de control solar con redireccionamiento de la luz
ES2629749T3 (es) Inmunidad tumoral
ES2647579T3 (es) Herramienta de corte con revestimiento multicapa
ES2605431T3 (es) Mejoras en preimpregnados
ES2502472T3 (es) Composición adhesiva para su uso en un inmunosensor
ES2513691T3 (es) Preparación transdérmica
JP2012084516A5 (es)
JP2018083424A5 (es)
CL2008000206A1 (es) Laminado elastomerico que comprende a) una capa de pelicula elastomerica con una primera y segunda superficie donde su peso base es menor a 70 gsm y b) una capa sustrato la cual contiene un material extensible con una deformacion por traccion en rupt
JP2007073500A5 (es)
JP2010532504A5 (es)
ES2569725T3 (es) Material compuesto reforzado con fibras con resistencia al fuego mejorada, y componente estructural fabricado del mismo
JP2011516929A5 (es)
JP2008541198A5 (es)
WO2010088423A3 (en) Shape memory riblets
ECSP099629A (es) Composición farmacéutica
JP2009522132A5 (es)
JP2010505661A5 (es)
JP2007042624A5 (es)
JP2012523912A5 (es)
CO6761347A2 (es) Luna de vidrio blindado teniendo refuerzo de borde
AR096315A1 (es) Laminado de seguridad
ES2586129T3 (es) Bisagra de material compuesto y proceso para su fabricación
ES2526215T3 (es) Pieza bidimensional