ES2523796T1 - Composición farmacéutica de liberación controlada que comprende éster de ácido fumárico - Google Patents
Composición farmacéutica de liberación controlada que comprende éster de ácido fumárico Download PDFInfo
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- ES2523796T1 ES2523796T1 ES14172396.5T ES14172396T ES2523796T1 ES 2523796 T1 ES2523796 T1 ES 2523796T1 ES 14172396 T ES14172396 T ES 14172396T ES 2523796 T1 ES2523796 T1 ES 2523796T1
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
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Abstract
Composición farmacéutica de liberación controlada para uso oral que consiste en fumarato de dimetilo como principio activo, en la que la dosificación diaria es de desde 480 hasta 720 mg de principio activo administrado en de una a tres dosis, en la que la composición es para su uso en el tratamiento de una enfermedad autoinmunitaria, en la que la enfermedad autoinmunitaria se selecciona de: i. poliartritis ii. esclerosis múltiple(EM) iii. diabetes mellitus de comienzo juvenil iv. tiroiditis de Hashimoto v. enfermedad de Grave vi. LES (lupus eritematoso sistémico) vii. síndrome de Sjogren viii. anemia perniciosa ix. hepatitis crónica activa (lupoide) x. arthritis reumatoide (AR) xi. neuritis óptica.
Claims (11)
- REIVINDICACIONES1.Composición farmacéutica de liberación controlada para uso oral que consiste en fumarato de dimetilo como principio activo, en la que la dosificación diaria es de desde 480 hasta 720 mg de principio activo administrado en de una a tres dosis, en la que la composición es para su uso en el tratamiento de una enfermedad autoinmunitaria, en la que la enfermedad autoinmunitaria se selecciona de:i. poliartritisii. esclerosis múltiple(EM)iii. diabetes mellitus de comienzo juvenil
- iv.
- tiroiditis de Hashimoto
- v.
- enfermedad de Grave
vi. LES (lupus eritematoso sistémico)vii. síndrome de Sjogrenviii. anemia perniciosa- ix.
- hepatitis crónica activa (lupoide)
- x.
- arthritis reumatoide (AR)
xi. neuritis óptica. -
- 2.
- Composición según la reivindicación 1, que es una forma de dosificación de liberación controlada por el pH.
-
- 3.
- Composición según la reivindicación 2, que está dotada de un recubrimiento entérico.
-
- 4.
- Composición según la reivindicación 3, que es una composición multiparticulada y las unidades individuales de la misma están dotadas de un recubrimiento entérico.
-
- 5.
- Composición según la reivindicación 1, en la que la dosificación diaria es de desde 480 hasta 600 mg de principio activo.
-
- 6.
- Composición según la reivindicación 1, en la que la dosificación diaria es de desde 600 hasta 720 mg de principio activo.
-
- 7.
- Composición según la reivindicación 1, en la que la dosificación diaria es de 480 mg de principio activo.
-
- 8.
- Composición según la reivindicación 1, en la que la forma de dosificación contiene 120, 180 ó 240 mg de principio activo.
-
- 9.
- Composición según la reivindicación 1, en la que la enfermedad autoinmunitaria es esclerosis múltiple.
- 10.Composición farmacéutica de liberación controlada para uso oral que consiste en fumarato de dimetilo como principio activo, en la que la dosificación diaria es de 480 mg de principio activo administrado en de una a tres dosis, en la que la composición es para su uso en el tratamiento de una enfermedad autoinmunitaria, en la que la enfermedad autoinmunitaria se selecciona de:i. poliartritisii. esclerosismúltiple(EM)iii. diabetesmellitusdecomienzojuvenil
- iv.
- tiroiditisdeHashimoto
- v.
- enfermedaddeGrave
vi. LES(lupuseritematososistémico)vii. síndromedeSjogrenviii. anemiaperniciosa- ix.
- hepatitiscrónicaactiva(lupoide)
- x.
- artritisreumatoide(AR)
xi. neuritisóptica. - 11. Composición según la reivindicación 10, para su uso en el tratamiento de esclerosis múltiple.2
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK200401546 | 2004-10-08 | ||
DKPA200401546 | 2004-10-08 | ||
DKPA200401736 | 2004-11-10 | ||
DK200401736 | 2004-11-10 | ||
DKPA200500211 | 2005-02-11 | ||
DK200500211 | 2005-02-11 | ||
DK200500419 | 2005-03-23 | ||
DKPA200500419 | 2005-03-23 | ||
US69151305P | 2005-06-16 | 2005-06-16 | |
US691513P | 2005-06-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2523796T1 true ES2523796T1 (es) | 2014-12-01 |
Family
ID=50726313
Family Applications (5)
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