ES2301649T3 - Procedimiento para la preparacion de n-(3-dimetilamino)alquilcarbamatos de alquilo. - Google Patents

Procedimiento para la preparacion de n-(3-dimetilamino)alquilcarbamatos de alquilo. Download PDF

Info

Publication number: ES2301649T3
Authority: ES; Spain
Prior art keywords: propyl; dimethylamino; procedure; chloroformate; preparation
Prior art date: 2001-05-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

ES02740612T

Other languages

English (en)

Spanish (es)

Inventor

Johannes Keuchel

Gunter Schlegel

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bayer CropScience AG

Original Assignee

Bayer CropScience AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-03

Filing date

2002-04-18

Publication date

2008-07-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26076565&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2301649(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-05-03 Priority claimed from EP01110711A external-priority patent/EP1254894A1/de

2001-06-06 Priority claimed from EP01113778A external-priority patent/EP1264824A1/de

2002-04-18 Application filed by Bayer CropScience AG filed Critical Bayer CropScience AG

2008-07-01 Application granted granted Critical

2008-07-01 Publication of ES2301649T3 publication Critical patent/ES2301649T3/es

2022-04-18 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

238000000034 method Methods 0.000 title claims abstract description 22
238000002360 preparation method Methods 0.000 title claims abstract description 8
239000000203 mixture Substances 0.000 claims abstract description 9
150000001298 alcohols Chemical class 0.000 claims abstract description 8
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 6
125000000217 alkyl group Chemical group 0.000 claims abstract description 5
239000003960 organic solvent Substances 0.000 claims abstract description 5
125000001931 aliphatic group Chemical group 0.000 claims abstract description 3
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical group CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims description 12
238000006243 chemical reaction Methods 0.000 claims description 10
125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 9
FZFAMSAMCHXGEF-UHFFFAOYSA-N chloro formate Chemical compound ClOC=O FZFAMSAMCHXGEF-UHFFFAOYSA-N 0.000 claims description 7
RHLCLUWWRHEMDQ-UHFFFAOYSA-N 3-(dimethylamino)propylcarbamic acid Chemical compound CN(C)CCCNC(O)=O RHLCLUWWRHEMDQ-UHFFFAOYSA-N 0.000 claims description 4
239000003153 chemical reaction reagent Substances 0.000 claims description 2
239000002904 solvent Substances 0.000 claims description 2
-1 alkyl chloroformate Chemical compound 0.000 abstract description 3
YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 21
IUNMPGNGSSIWFP-UHFFFAOYSA-N dimethylaminopropylamine Chemical compound CN(C)CCCN IUNMPGNGSSIWFP-UHFFFAOYSA-N 0.000 description 7
QQKDTTWZXHEGAQ-UHFFFAOYSA-N propyl carbonochloridate Chemical compound CCCOC(Cl)=O QQKDTTWZXHEGAQ-UHFFFAOYSA-N 0.000 description 6
239000012442 inert solvent Substances 0.000 description 4
YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
230000015556 catabolic process Effects 0.000 description 3
238000006731 degradation reaction Methods 0.000 description 3
150000002170 ethers Chemical class 0.000 description 3
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical group Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 description 2
WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
239000002253 acid Substances 0.000 description 2
150000001875 compounds Chemical class 0.000 description 2
YNTOKMNHRPSGFU-UHFFFAOYSA-N n-Propyl carbamate Chemical compound CCCOC(N)=O YNTOKMNHRPSGFU-UHFFFAOYSA-N 0.000 description 2
WZZLDXDUQPOXNW-UHFFFAOYSA-N propamocarb Chemical compound CCCOC(=O)NCCCN(C)C WZZLDXDUQPOXNW-UHFFFAOYSA-N 0.000 description 2
DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 description 1
QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 description 1
KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 description 1
BZLVMXJERCGZMT-UHFFFAOYSA-N Methyl tert-butyl ether Chemical compound COC(C)(C)C BZLVMXJERCGZMT-UHFFFAOYSA-N 0.000 description 1
239000013543 active substance Substances 0.000 description 1
150000001412 amines Chemical class 0.000 description 1
238000009835 boiling Methods 0.000 description 1
229910002092 carbon dioxide Inorganic materials 0.000 description 1
239000001569 carbon dioxide Substances 0.000 description 1
125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 description 1
230000000855 fungicidal effect Effects 0.000 description 1
239000000417 fungicide Substances 0.000 description 1
SNMVRZFUUCLYTO-UHFFFAOYSA-N n-propyl chloride Chemical compound CCCCl SNMVRZFUUCLYTO-UHFFFAOYSA-N 0.000 description 1
239000001294 propane Substances 0.000 description 1
239000011541 reaction mixture Substances 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
238000000926 separation method Methods 0.000 description 1
238000010561 standard procedure Methods 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C255/46—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of non-condensed rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ES02740612T 2001-05-03 2002-04-18 Procedimiento para la preparacion de n-(3-dimetilamino)alquilcarbamatos de alquilo. Expired - Lifetime ES2301649T3 (es)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
EP01110711A EP1254894A1 (de)	2001-05-03	2001-05-03	Verfahren zur Herstellung von Propamocarb
EP01110711		2001-05-03
EP01113778A EP1264824A1 (de)	2001-06-06	2001-06-06	Herstellung von Alkyl N-(3-dimethylamin)alkylcarbaminsäureestern
EP01113778		2001-06-06

Publications (1)

Publication Number	Publication Date
ES2301649T3 true ES2301649T3 (es)	2008-07-01

Family

ID=26076565

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES02740612T Expired - Lifetime ES2301649T3 (es)	2001-05-03	2002-04-18	Procedimiento para la preparacion de n-(3-dimetilamino)alquilcarbamatos de alquilo.

Country Status (21)

Country	Link
US (1)	US6872847B2 (de)
EP (1)	EP1383737B1 (de)
JP (1)	JP4261915B2 (de)
KR (1)	KR100867910B1 (de)
CN (1)	CN1246305C (de)
AT (1)	ATE386015T1 (de)
AU (1)	AU2002314078B2 (de)
BR (1)	BR0209410A (de)
CA (1)	CA2443820C (de)
CZ (1)	CZ299629B6 (de)
DE (1)	DE60224998T2 (de)
DK (1)	DK1383737T3 (de)
ES (1)	ES2301649T3 (de)
HU (1)	HUP0303821A3 (de)
IL (2)	IL158015A0 (de)
MX (1)	MXPA03010032A (de)
PL (1)	PL203712B1 (de)
PT (1)	PT1383737E (de)
SK (1)	SK287055B6 (de)
TW (1)	TWI247732B (de)
WO (1)	WO2002090322A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101548682B (zh) *	2009-04-14	2012-07-25	陕西恒田化工有限公司	一种合成722克/升霜霉威盐酸盐的方法
BR112019006239A2 (pt) *	2016-10-31	2019-06-18	Eastman Chem Co	processo para preparar 3-(dimetilamino)propilcarbamato de propila.
CN108218745A (zh) *	2018-03-12	2018-06-29	浙江禾本科技有限公司	一种霜霉威盐酸盐合成配方及其合成方法
CN113563230B (zh) *	2020-08-24	2023-04-11	江苏禾本生化有限公司	一种霜霉威盐酸盐原药的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL157191C (nl) *	1966-12-17		Schering Ag	Werkwijze voor het bereiden van een preparaat met fungicide en fungistatische werking.
DE4133516A1 (de) *	1991-10-10	1993-04-15	Bayer Ag	Verfahren zur herstellung von n-(hydroxyalkyl)-carbamidsaeure-alkylestern

2002
- 2002-04-18 AU AU2002314078A patent/AU2002314078B2/en not_active Ceased
- 2002-04-18 MX MXPA03010032A patent/MXPA03010032A/es active IP Right Grant
- 2002-04-18 CA CA002443820A patent/CA2443820C/en not_active Expired - Fee Related
- 2002-04-18 DE DE60224998T patent/DE60224998T2/de not_active Expired - Lifetime
- 2002-04-18 PL PL366847A patent/PL203712B1/pl not_active IP Right Cessation
- 2002-04-18 BR BR0209410-0A patent/BR0209410A/pt not_active Application Discontinuation
- 2002-04-18 ES ES02740612T patent/ES2301649T3/es not_active Expired - Lifetime
- 2002-04-18 AT AT02740612T patent/ATE386015T1/de active
- 2002-04-18 DK DK02740612T patent/DK1383737T3/da active
- 2002-04-18 WO PCT/EP2002/005456 patent/WO2002090322A1/en active IP Right Grant
- 2002-04-18 HU HU0303821A patent/HUP0303821A3/hu unknown
- 2002-04-18 SK SK1477-2003A patent/SK287055B6/sk not_active IP Right Cessation
- 2002-04-18 EP EP02740612A patent/EP1383737B1/de not_active Expired - Lifetime
- 2002-04-18 CZ CZ20033261A patent/CZ299629B6/cs not_active IP Right Cessation
- 2002-04-18 IL IL15801502A patent/IL158015A0/xx unknown
- 2002-04-18 JP JP2002587402A patent/JP4261915B2/ja not_active Expired - Lifetime
- 2002-04-18 US US10/476,706 patent/US6872847B2/en not_active Expired - Lifetime
- 2002-04-18 PT PT02740612T patent/PT1383737E/pt unknown
- 2002-04-18 KR KR1020037014063A patent/KR100867910B1/ko active IP Right Grant
- 2002-04-18 CN CNB028093399A patent/CN1246305C/zh not_active Expired - Lifetime
- 2002-04-24 TW TW091108426A patent/TWI247732B/zh not_active IP Right Cessation
2003
- 2003-09-18 IL IL158015A patent/IL158015A/en unknown

Also Published As

Publication number	Publication date
JP4261915B2 (ja)	2009-05-13
ATE386015T1 (de)	2008-03-15
PT1383737E (pt)	2008-03-17
DK1383737T3 (da)	2008-03-17
AU2002314078B2 (en)	2007-01-11
KR20030094370A (ko)	2003-12-11
IL158015A0 (en)	2004-03-28
CA2443820A1 (en)	2002-11-14
DE60224998D1 (de)	2008-03-27
CZ20033261A3 (en)	2004-03-17
JP2004526801A (ja)	2004-09-02
CA2443820C (en)	2009-08-18
US20040152914A1 (en)	2004-08-05
HUP0303821A3 (en)	2007-02-28
SK287055B6 (sk)	2009-10-07
TWI247732B (en)	2006-01-21
PL366847A1 (en)	2005-02-07
WO2002090322A1 (en)	2002-11-14
BR0209410A (pt)	2004-07-06
KR100867910B1 (ko)	2008-11-10
US6872847B2 (en)	2005-03-29
EP1383737A1 (de)	2004-01-28
CN1507433A (zh)	2004-06-23
SK14772003A3 (sk)	2004-05-04
DE60224998T2 (de)	2009-02-05
MXPA03010032A (es)	2004-02-27
HUP0303821A2 (hu)	2004-03-29
PL203712B1 (pl)	2009-11-30
IL158015A (en)	2009-05-04
EP1383737B1 (de)	2008-02-13
CZ299629B6 (cs)	2008-09-24
CN1246305C (zh)	2006-03-22

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