ES2179114T3 - Sistemas de diagnostico automatizados de biologia molecular. - Google Patents

Sistemas de diagnostico automatizados de biologia molecular.

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Publication number
ES2179114T3
ES2179114T3 ES95931746T ES95931746T ES2179114T3 ES 2179114 T3 ES2179114 T3 ES 2179114T3 ES 95931746 T ES95931746 T ES 95931746T ES 95931746 T ES95931746 T ES 95931746T ES 2179114 T3 ES2179114 T3 ES 2179114T3
Authority
ES
Spain
Prior art keywords
reactions
self
microlocations
molecular biological
controller interfaces
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95931746T
Other languages
English (en)
Inventor
Michael J Heller
Eugene Tu
Donald D Montgomery
William F Butler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanogen Inc
Original Assignee
Nanogen Inc
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Filing date
Publication date
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Publication of ES2179114T3 publication Critical patent/ES2179114T3/es
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    • G11C13/0014—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material
    • G11C13/0019—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material comprising bio-molecules
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Abstract

UN SISTEMA MICROELECTRONICO AUTOENSAMBLABLE Y AUTODIRIGIBLE PARA REALIZAR DIAGNOSTICOS, ANALISIS, REACCIONES MULTIETAPA Y MULTIPLES MOLECULARES EN FORMATOS MICROSCOPICOS. UNAS REACCIONES CONTROLADAS ACTIVAMENTE INCLUYEN LA HIBRIDACION DE ACIDO NUCLEICO, INMUNOENSAYOS, DIAGNOSTICOS CLINICOS Y SINTESIS COMBINATORIA MULTIETAPA DE BIOPOLIMEROS. EL CONTROLADOR SE INTERCONECTA CON EL USUARIO VIA UNOS DISPOSITIVOS DE ENTRADA/SALIDA QUE INCLUYEN PREFERENTEMENTE UNA PANTALLA GRAFICA. EL CONTROLADOR PODRA INTERCONECTARSE CON UNA FUENTE DE ALIMENTACION Y UNA INTERFAZ, SUMINISTRANDO LA INTERFAZ UNA CONEXION SELECTIVA A MICROLOCALIZACIONES INDIVIDUALES, INVERSION DE POLARIDAD Y NIVELES DE POTENCIAL O CORRIENTE SELECTIVAS A ELECTRODOS INDIVIDUALES. UN SISTEMA COMBINADO PARA REALIZAR LA PREPARACION, HIBRIDACION, DETECCION Y ANALISIS DE DATOS DE MUESTRAS DE DNA INTEGRA ETAPAS MULTIPLES. UNOS MATERIALES CARGADOS SE TRANSFORMAN PREFERENTEMENTE POR ELECTROPOROSIS DE CAMPO LIBRE. LA REDUCCION DE COMPLEJIDAD DEL DNA SE CONSIGUE PREFERENTEMENTE MEDIANTE LA UNION DEL DNA A UN SOPORTE, ROMPIENDOSE LOS MATERIALES NO ENLAZADOS, COMO POR EJEMPLO POR ENZIMAS DE RESTRICCION Y TRANSPORTANDO LOS FRAGMENTOS ROTOS. UNOS DISPOSITIVOS DE MATRIZ ACTIVA PROGRAMABLE INCLUYEN UNA PAUTA DE MATRIZ CUADRADA CON CONEXIONES ELECTRICAS EN ABANICO Y CONEXIONES ELECTRICAS OPCIONALES DEBAJO DE MICROLOCALIZACIONES ESPECIFICAS QUE DAN COMO RESULTADO UN SISTEMA DE DIAGNOSTICO DE DNA ALTAMENTE AUTOMATIZADO.
ES95931746T 1994-09-09 1995-09-06 Sistemas de diagnostico automatizados de biologia molecular. Expired - Lifetime ES2179114T3 (es)

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US08/304,657 US5632957A (en) 1993-11-01 1994-09-09 Molecular biological diagnostic systems including electrodes

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DE69527375T2 (de) 2003-02-13
CN1121614C (zh) 2003-09-17
WO1996007917A1 (en) 1996-03-14
CA2199515A1 (en) 1996-03-14
DK0871888T3 (da) 2002-10-14
BR9508908A (pt) 1997-10-28
CA2199515C (en) 2003-05-20
ATE220459T1 (de) 2002-07-15
US6582660B1 (en) 2003-06-24
CN1164894A (zh) 1997-11-12
FI970957A0 (fi) 1997-03-06
EP0871888A1 (en) 1998-10-21
AU702773B2 (en) 1999-03-04
JPH10505497A (ja) 1998-06-02
US5632957A (en) 1997-05-27
EP0871888B1 (en) 2002-07-10
DE69527375D1 (de) 2002-08-14
FI970957A (fi) 1997-05-07
EP0871888A4 (es) 1998-10-21
AU3507095A (en) 1996-03-27

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