ES2169730T3 - Patron sintetico para analisis inmunologicos. - Google Patents
Patron sintetico para analisis inmunologicos.Info
- Publication number
- ES2169730T3 ES2169730T3 ES94116387T ES94116387T ES2169730T3 ES 2169730 T3 ES2169730 T3 ES 2169730T3 ES 94116387 T ES94116387 T ES 94116387T ES 94116387 T ES94116387 T ES 94116387T ES 2169730 T3 ES2169730 T3 ES 2169730T3
- Authority
- ES
- Spain
- Prior art keywords
- immunological analysis
- synthetic pattern
- analyte
- conjugate
- test
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4716—Muscle proteins, e.g. myosin, actin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
- G01N2333/75—Fibrin; Fibrinogen
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/961—Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/973—Simultaneous determination of more than one analyte
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Peptides Or Proteins (AREA)
- Sampling And Sample Adjustment (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
LA INVENCION SE REFIERE A UN CONJUGADO DE AL MENOS DOS LUGARES DE ENLACE, QUE SE UTILIZA ESPECIFICAMENTE CON LA REGION DE ENLACE ESPECIFICA DE ANALISIS DEL RECEPTOR, PARA LA COMPROBACION EN UN TEST, DONDE LOS LUGARES DE ENLACE ESTAN UNIDOS POR MEDIO AL MENOS DE UNA SUSTANCIA SOPORTE SOLUBLE Y DE FORMA QUE EL CONJUGADO ES EL PRODUCTO DE UNA ELABORACION SINTETICA O RECOMBINANTE, DISUELTO EN SOLUCION ACUOSA EN UNA CANTIDAD CONOCIDA EXACTAMENTE, SIENDO APROPIADO COMO CALIBRADOR ESTABLE EN UN TEST PARA LA CONFORMACION DE UN ANALISIS.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4335798 | 1993-10-20 | ||
DE4335798 | 1993-10-20 | ||
DE4417735 | 1994-05-20 | ||
DE4417735 | 1994-05-20 | ||
DE4420742A DE4420742A1 (de) | 1993-10-20 | 1994-06-15 | Synthetischer Standard für Immunoassays |
DE4420742 | 1994-06-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2169730T3 true ES2169730T3 (es) | 2002-07-16 |
ES2169730T5 ES2169730T5 (es) | 2006-05-16 |
Family
ID=27205682
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94116387T Expired - Lifetime ES2169730T5 (es) | 1993-10-20 | 1994-10-17 | Patron sintetico para analisis inmunologicos. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5846738A (es) |
EP (1) | EP0650053B2 (es) |
JP (1) | JP2575296B2 (es) |
AT (1) | ATE210827T1 (es) |
DE (2) | DE4420742A1 (es) |
ES (1) | ES2169730T5 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2734267B1 (fr) * | 1995-05-16 | 1997-08-01 | Pasteur Sanofi Diagnostics | Composition stabilisee de troponine pour immunoessais et procede de preparation d'une telle composition stabilisee |
DE19524572A1 (de) * | 1995-07-06 | 1997-01-09 | Bayer Ag | Verfahren zur Herstellung eines synthetischen Kalibrators für den Einsatz in Immunoassays, bestehend aus den Analyten oder Teilsequenzen davon, die an inerten Trägermoleküle konjugiert sind |
DE19548028A1 (de) * | 1995-12-21 | 1997-06-26 | Bayer Ag | Verfahren zur Herstellung eines synthetischen Kalibrators für den Einsatz in Sandwich-Immunoassays, bestehend aus einem Antikörper gegen einen der im Assay benutzten Antikörper und einer Sequenz des Analyten |
DE19637803A1 (de) * | 1996-09-17 | 1998-03-19 | Boehringer Mannheim Gmbh | Stabilisierung von Standardlösungen durch Konjugate |
US6072040A (en) * | 1996-10-15 | 2000-06-06 | Medical Analysis Systems, Inc. | Stabilized conjugates of uncomplexed subunits of multimeric proteins |
FR2756827B1 (fr) * | 1996-12-05 | 1999-01-29 | Pasteur Sanofi Diagnostics | Composes synthetiques biepitopiques utilisables comme etalons dans les dosages biologiques de la troponine i |
US6939466B2 (en) * | 1998-08-17 | 2005-09-06 | Cuno Incorporated | Graded particle-size retention filter medium for fluid filtration unit with improved edge seal |
WO2000023585A1 (en) | 1998-10-21 | 2000-04-27 | Spectral Diagnostics, Inc. | Cardiac troponin i polypeptide fragments and uses in diagnostics |
US6190916B1 (en) * | 1999-06-29 | 2001-02-20 | Spectral Diagnostics, Inc. | Troponin I composition |
FR2797689B1 (fr) * | 1999-08-16 | 2003-06-27 | Pasteur Sanofi Diagnostics | Utilisation de composes synthetiques pour des immunodosages |
US20050266398A1 (en) * | 2004-06-01 | 2005-12-01 | Peter Lea | Method and device for rapid detection and quantitation of macro and micro matrices |
CA2475240A1 (en) * | 2004-07-20 | 2006-01-20 | Biophys, Inc. | Method and device to measure dynamic internal calibration true dose response curves |
CA2475456A1 (en) * | 2004-07-20 | 2006-01-20 | Biophys, Inc. | Method and device to optimize analyte and antibody substrate binding by least energy adsorption |
WO2007103734A2 (en) * | 2006-03-03 | 2007-09-13 | Ciphergen Biosystems, Inc. | Method for quantifying an analyte in a biological sample using mass spectrometry |
US20110076697A1 (en) * | 2009-04-28 | 2011-03-31 | Innovative Laboratory Technologies, Inc. | Lateral-flow immuno-chromatographic assay devices |
US20110306148A1 (en) | 2010-06-14 | 2011-12-15 | Siemens Healthcare Diagnostics Inc. | Composition for use as an assay reagent |
KR20170095364A (ko) | 2014-12-18 | 2017-08-22 | 비오메리으 | 합성 이중-에피토프 화합물 |
CN105628941B (zh) * | 2015-12-22 | 2017-09-22 | 北京康彻思坦生物技术有限公司 | 一种IgM血清学检测质控物的制备方法 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4271140A (en) * | 1978-01-23 | 1981-06-02 | Baxter Travenol Laboratories, Inc. | Method and composition for double receptor, specific binding assays |
EP0008473B1 (en) * | 1978-08-24 | 1983-06-01 | Akzo N.V. | Method for the detection and/or determination of an antigen specific immunoglobulin, immuno-reagents to be used in said method and test kit for said determination |
DE3112334A1 (de) * | 1981-03-28 | 1982-10-07 | Behringwerke Ag, 3550 Marburg | "kuenstliche kontroll- und standardseren, verfahren zu ihrer herstellung und ihre verwendung" |
US4886663A (en) * | 1983-01-03 | 1989-12-12 | Scripps Clinic And Research Foundation | Synthetic heat-stable enterotoxin polypeptide of Escherichia coli and multimers thereof |
US4859765A (en) * | 1983-10-17 | 1989-08-22 | Syntex (U.S.A.) Inc. | Synthetic peptide sequences useful in biological and pharmaceutical applications and methods of manufacture |
DE3400434A1 (de) * | 1984-01-09 | 1985-09-26 | Behringwerke Ag, 3550 Marburg | Bestimmung von fibrin mit fibrin-spezifischen antikoerpern |
US5357042A (en) * | 1984-04-23 | 1994-10-18 | The General Hospital Corporation | Synthetic peptides capable of eliciting fibrin-specific monoclonal antibodies lacking fibrinogen-cross-reactivity |
JP2564268B2 (ja) * | 1985-08-28 | 1996-12-18 | 協和醗酵工業株式会社 | 融合抗原ポリペプチド |
DE3730059A1 (de) * | 1987-09-08 | 1989-03-30 | Behringwerke Ag | Verfahren zur bestimmung von "loeslichem" fibrin |
US5206086A (en) † | 1987-10-13 | 1993-04-27 | University Of Rochester | Particle-stabilized epitopes for standardization and control of immunoassays |
EP0339695A3 (en) * | 1988-04-29 | 1990-05-30 | Stichting Voor De Technische Wetenschappen | A process for preparing an antigenic or immunogenic conjugate as well as the use of such conjugates |
DE3822750A1 (de) * | 1988-07-05 | 1990-01-11 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung einer spezifisch bindefaehigen substanz |
DE3922873A1 (de) * | 1989-04-25 | 1990-10-31 | Boehringer Mannheim Gmbh | Spezifische antikoerper gegen troponin t, ihre herstellung und verwendung in einem reagenz zur bestimmung von hermuskelnekrosen |
JPH03200065A (ja) * | 1989-12-28 | 1991-09-02 | Tosoh Corp | 免疫測定用参照品及びその製造方法 |
KR940000755B1 (ko) * | 1990-02-16 | 1994-01-29 | 유나이티드 바이오메디칼 인코오포레이티드 | Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드 |
US5223393A (en) * | 1990-06-12 | 1993-06-29 | Microgenics Corporation | Detection of analytes having binding sites for at least two binding moieties |
JPH04233458A (ja) * | 1990-08-23 | 1992-08-21 | New York Blood Center Inc | 可溶性フィブリン様モノマーを使ったアッセイ |
AU3603693A (en) * | 1992-02-04 | 1993-09-01 | Ohmicron Corporation | Immunological analogs for captan |
CN1111540C (zh) * | 1993-06-09 | 2003-06-18 | 康诺特实验室有限公司 | 串联的合成hiv-1肽类 |
-
1994
- 1994-06-15 DE DE4420742A patent/DE4420742A1/de not_active Withdrawn
- 1994-10-17 EP EP94116387A patent/EP0650053B2/de not_active Expired - Lifetime
- 1994-10-17 AT AT94116387T patent/ATE210827T1/de not_active IP Right Cessation
- 1994-10-17 ES ES94116387T patent/ES2169730T5/es not_active Expired - Lifetime
- 1994-10-17 DE DE59410003T patent/DE59410003D1/de not_active Expired - Fee Related
- 1994-10-20 JP JP6255805A patent/JP2575296B2/ja not_active Expired - Fee Related
-
1996
- 1996-12-12 US US08/762,695 patent/US5846738A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0650053A1 (de) | 1995-04-26 |
EP0650053B1 (de) | 2001-12-12 |
DE59410003D1 (de) | 2002-01-24 |
DE4420742A1 (de) | 1995-04-27 |
ES2169730T5 (es) | 2006-05-16 |
EP0650053B2 (de) | 2005-11-30 |
ATE210827T1 (de) | 2001-12-15 |
JP2575296B2 (ja) | 1997-01-22 |
JPH07191024A (ja) | 1995-07-28 |
US5846738A (en) | 1998-12-08 |
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Legal Events
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