ES2068844T3 - Dispositivo analitico en fase solida y metodo para su utilizacion. - Google Patents
Dispositivo analitico en fase solida y metodo para su utilizacion.Info
- Publication number
- ES2068844T3 ES2068844T3 ES89105114T ES89105114T ES2068844T3 ES 2068844 T3 ES2068844 T3 ES 2068844T3 ES 89105114 T ES89105114 T ES 89105114T ES 89105114 T ES89105114 T ES 89105114T ES 2068844 T3 ES2068844 T3 ES 2068844T3
- Authority
- ES
- Spain
- Prior art keywords
- analyte
- assay
- solid phase
- analytical device
- phase analytical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/521—Single-layer analytical elements
- G01N33/523—Single-layer analytical elements the element being adapted for a specific analyte
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/528—Atypical element structures, e.g. gloves, rods, tampons, toilet paper
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5761—Hepatitis B
- G01N33/5764—Hepatitis B surface antigen
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Reproductive Health (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Un dispositivo de prueba para utilizar en un ensayo de fijación para determinar la presencia o cantidad de un analito en una muestra líquida con la adición de la muestra, reactivos adecuados y marca a un emplazamiento de reacción, en donde dicho emplazamiento de reacción tiene una primera área de control (30), una segunda área de control (32) que incluye medios para representar una respuesta detectable indicativa de un resultado de ensayo válido, y un área de fijación de analito (34) incluyendo medios para representar un resultado detectable indicativo de la presencia o cantidad del analito en la muestra fluida; caracterizado en que dicho dispositivo es una tira cromatográfica porosa (11) que tiene un emplazamiento de contacto a diferencia de dicho emplazamiento de reacción para poner en contacto una muestra fluida y medios (12) para transportar la muestra fluida por capilaridad o mecha al emplazamiento de reacción, tal que dicha muestra fluida uye a través de dicho emplazamiento de reacción de extremo a extremo; y en el que el símbolo detectable producido por la segunda área de control (32) interactúa con el símbolo producido por el área de fijación de analito (34) en la presencia de analito para formar un símbolo interactivo representativo de un resultado positivo, mientras que el símbolo producido por la segunda área de control (32) tomado sólo es representativo de un resultado negativo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/173,979 US4916056A (en) | 1986-02-18 | 1988-03-28 | Solid-phase analytical device and method for using same |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2068844T3 true ES2068844T3 (es) | 1995-05-01 |
Family
ID=22634314
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89105114T Expired - Lifetime ES2068844T3 (es) | 1988-03-28 | 1989-03-22 | Dispositivo analitico en fase solida y metodo para su utilizacion. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4916056A (es) |
EP (1) | EP0335244B1 (es) |
JP (1) | JP2818191B2 (es) |
KR (1) | KR920009420B1 (es) |
AT (1) | ATE116443T1 (es) |
AU (1) | AU618586B2 (es) |
CA (1) | CA1332807C (es) |
DE (1) | DE68920176T2 (es) |
ES (1) | ES2068844T3 (es) |
Families Citing this family (152)
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TW203120B (es) * | 1985-10-04 | 1993-04-01 | Abbott Lab | |
US5160701A (en) * | 1986-02-18 | 1992-11-03 | Abbott Laboratories | Solid-phase analytical device and method for using same |
US5250412A (en) * | 1987-03-23 | 1993-10-05 | Diamedix Corporation | Swab device and method for collecting and analyzing a sample |
EP1555529A3 (en) | 1987-04-27 | 2008-06-04 | Inverness Medical Switzerland GmbH | Immunochromatographic specific binding assay device and method. |
US5120643A (en) * | 1987-07-13 | 1992-06-09 | Abbott Laboratories | Process for immunochromatography with colloidal particles |
US5073344A (en) * | 1987-07-17 | 1991-12-17 | Porex Technologies Corp. | Diagnostic system employing a unitary substrate to immobilize microspheres |
WO1989001626A1 (en) * | 1987-08-19 | 1989-02-23 | Flemming Gmbh | Process and device for detecting an antigen or antibody in a liquid test specimen |
DE3740471A1 (de) * | 1987-11-28 | 1989-06-08 | Boehringer Mannheim Gmbh | Testtraeger zur analyse einer probenfluessigkeit und verfahren zu seiner herstellung |
CA1339723C (en) * | 1988-01-19 | 1998-03-17 | Philip Mcmahon | Immunoassay with multiple test spots |
AU2684488A (en) | 1988-06-27 | 1990-01-04 | Carter-Wallace, Inc. | Test device and method for colored particle immunoassay |
IT1227293B (it) * | 1988-10-06 | 1991-04-05 | Boehringer Biochemia Srl | Dispositivo e metodo per la diagnosi di gravidanza |
JPH02176466A (ja) * | 1988-12-27 | 1990-07-09 | Mochida Pharmaceut Co Ltd | 液性試料中の特定物質の測定方法および測定器具 |
CA2008304C (en) * | 1989-01-31 | 2001-03-27 | Craig S. Hill | Assay for bone alkaline phosphatase |
US6352862B1 (en) * | 1989-02-17 | 2002-03-05 | Unilever Patent Holdings B.V. | Analytical test device for imuno assays and methods of using same |
GB2233090B (en) * | 1989-04-19 | 1992-03-25 | Pall Corp | Multilayered diagnostic device and method |
US5100620A (en) * | 1989-05-15 | 1992-03-31 | Miles, Inc. | Capillary tube/gap reagent format |
ATE117804T1 (de) * | 1989-06-05 | 1995-02-15 | Janssen Pharmaceutica Nv | Festphasen-test zur verwendung mit einem physikalischen entwickler. |
US5185127A (en) * | 1989-09-21 | 1993-02-09 | Becton, Dickinson And Company | Test device including flow control means |
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-
1988
- 1988-03-28 US US07/173,979 patent/US4916056A/en not_active Expired - Lifetime
-
1989
- 1989-03-21 AU AU31564/89A patent/AU618586B2/en not_active Ceased
- 1989-03-22 EP EP89105114A patent/EP0335244B1/en not_active Expired - Lifetime
- 1989-03-22 ES ES89105114T patent/ES2068844T3/es not_active Expired - Lifetime
- 1989-03-22 AT AT89105114T patent/ATE116443T1/de not_active IP Right Cessation
- 1989-03-22 DE DE68920176T patent/DE68920176T2/de not_active Expired - Lifetime
- 1989-03-23 CA CA000594550A patent/CA1332807C/en not_active Expired - Lifetime
- 1989-03-27 JP JP1076382A patent/JP2818191B2/ja not_active Expired - Fee Related
- 1989-03-27 KR KR1019890003817A patent/KR920009420B1/ko not_active IP Right Cessation
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AU3156489A (en) | 1989-09-28 |
KR920009420B1 (ko) | 1992-10-16 |
CA1332807C (en) | 1994-11-01 |
DE68920176D1 (de) | 1995-02-09 |
JP2818191B2 (ja) | 1998-10-30 |
US4916056A (en) | 1990-04-10 |
AU618586B2 (en) | 1992-01-02 |
EP0335244A2 (en) | 1989-10-04 |
EP0335244A3 (en) | 1990-05-30 |
DE68920176T2 (de) | 1995-05-11 |
ATE116443T1 (de) | 1995-01-15 |
JPH01299464A (ja) | 1989-12-04 |
EP0335244B1 (en) | 1994-12-28 |
KR890015016A (ko) | 1989-10-28 |
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