ES2162371T3 - Metodo para medir la hemoglobina glucosilada. - Google Patents

Metodo para medir la hemoglobina glucosilada.

Info

Publication number
ES2162371T3
ES2162371T3 ES98109737T ES98109737T ES2162371T3 ES 2162371 T3 ES2162371 T3 ES 2162371T3 ES 98109737 T ES98109737 T ES 98109737T ES 98109737 T ES98109737 T ES 98109737T ES 2162371 T3 ES2162371 T3 ES 2162371T3
Authority
ES
Spain
Prior art keywords
hemoglobin
antibody
glucated
measuring
immunoaglutination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98109737T
Other languages
English (en)
Inventor
Masami Sugiyama
Yoshiaki Uchida
Yoshihiro Kurano
Aiko Tanaka
Tetsuji Tanimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujirebio Inc
Original Assignee
Fujirebio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujirebio Inc filed Critical Fujirebio Inc
Application granted granted Critical
Publication of ES2162371T3 publication Critical patent/ES2162371T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA MEDIR LA HEMOGLOBINA GLUCADA, EL CUAL INCLUYE PONER EN CONTACTO UNA MUESTRA CON UN ANTICUERPO DE ANTI-HEMOGLOBINA QUE ESTA LIGADO A UNA FASE SOLIDA, AÑADIR A LOS MISMOS UN ANTICUERPO DE HEMOGLOBINA ANTI-GLUCADA, Y ENTONCES MEDIR EL ANTICUERPO DE HEMOGLOBINA ANTIGLUCADA QUE ESTA LIGADO A LA FASE SOLIDA POR MEDIO DE LA HEMOGLOBINA GLUCADA Y DEL ANTICUERPO DE ANTI-HEMOGLOBINA. SE REVELA UN PROCEDIMIENTO ADICIONAL PARA MEDIR LA HEMOGLOBINA GLUCADA, EL CUAL INCLUYE MEZCLAR UNA MUESTRA CON UNAS PARTICULAS QUE ESTAN ENLAZADAS CON UN ANTICUERPO DE HEMOGLOBINA ANTI-GLUCADA PARA CAUSAR UNA REACCION DE INMUNOAGLUTINACION, Y ENTONCES MEDIR LAS AGLUTINACIONES FORMADAS POR LA REACCION DE INMUNOAGLUTINACION. ADEMAS, SE REVELA UN PROCEDIMIENTO PARA MEDIR LA HEMOGLOBINA GLUCADA, EL CUAL INCLUYE MEZCLAR UNA MUESTRA CON UNA SOLUCION QUE CONTIENE UN ANTICUERPO MONOCLONAL QUE ES ESPECIFICO A LA HEMOGLOBINA GLUCADA, Y ENTONCES MEDIR EL CAMBIO EN LA TURBULENCIA DE LA MEZCLA RESULTANTE. SE REVELA, TODAVIA, UN PROCEDIMIENTO PARA MEDIR LA HEMOGLOBINA GLUCADA, EL CUAL INCLUYE MEZCLAR UNA MUESTRA CON UNAS PARTICULAS DE LATEX SIN SENSIBILIZAR Y CON UN ANTICUERPO DE HEMOGLOBINA ANTI-GLUCADA, O CON UNAS PARTICULAS DE LATEX SIN SENSIBILIZAR Y SUBSIGUIENTEMENTE CON UN ANTICUERPO DE HEMOGLOBINA ANTI-GLUCADA, PARA CAUSAR UNA REACCION DE INMUNOAGLUTINACION, Y ENTONCES MEDIR LAS AGLUTINACIONES FORMADAS POR LA REACCION DE INMUNOAGLUTINACION. SE REVELA TODAVIA UN PROCEDIMIENTO ADICIONAL PARA MEDIR LA HEMOGLOBINA GLUCADA, EL CUAL INCLUYE MEZCLAR UNA MUESTRA CON UNAS PARTICULAS DE LATEX SENSIBILIZADAS Y CON UNAS PARTICULAS QUE ESTAN ENLAZADAS CON UN ANTICUERPO DE HEMOGLOBINA ANTI-GLUCADA, O CON UNAS PARTICULAS DE LATEX SIN SENSIBILIZAR Y SUBSIGUIENTEMENTE CON UNAS PARTICULAS QUE ESTAN ENLAZADAS CON UN ANTICUERPO DE HEMOGLOBINA ANTI-GLUCADA, PARA CAUSAR UNA REACCION DE INMUNOAGLUTINACION, Y ENTONCES MEDIR LAS AGLUTINACIONES FORMADAS POR LA REACCION DE INMUNOAGLUTINACION. TODAVIA MAS, SE REVELA UN ANTICUERPO MONOCLONAL DE HEMOGLOBINA ANTI-GLUCADA QUE TIENE UNA ESPECIFICIDAD PARA LA HEMOGLOBINA GLUCADA HUMANA.
ES98109737T 1992-06-10 1993-06-08 Metodo para medir la hemoglobina glucosilada. Expired - Lifetime ES2162371T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17744492 1992-06-10
JP18170892 1992-06-16

Publications (1)

Publication Number Publication Date
ES2162371T3 true ES2162371T3 (es) 2001-12-16

Family

ID=26497980

Family Applications (2)

Application Number Title Priority Date Filing Date
ES93109230T Expired - Lifetime ES2146595T3 (es) 1992-06-10 1993-06-08 Metodo para medir la hemoglobina glicosilada.
ES98109737T Expired - Lifetime ES2162371T3 (es) 1992-06-10 1993-06-08 Metodo para medir la hemoglobina glucosilada.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES93109230T Expired - Lifetime ES2146595T3 (es) 1992-06-10 1993-06-08 Metodo para medir la hemoglobina glicosilada.

Country Status (5)

Country Link
US (1) US5470759A (es)
EP (2) EP0573972B1 (es)
KR (2) KR100257985B1 (es)
DE (2) DE69328273T2 (es)
ES (2) ES2146595T3 (es)

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FR2721112B1 (fr) * 1994-06-13 1996-08-14 Gks Technologies Dispositif de diagnostic rapide de toute molécule glyquée et procédé de mise en Óoeuvre.
JP3551678B2 (ja) * 1996-03-14 2004-08-11 東ソー株式会社 ヘモグロビンＡ１ｃの測定法及びキット
US6162645A (en) * 1997-03-13 2000-12-19 Abbott Laboratories Determination of % glycated hemoglobin
US6316265B1 (en) 1997-03-13 2001-11-13 Abbott Laboratories Determination of % glycated hemoglobin
AU7487798A (en) * 1997-05-29 1998-12-30 Bio-Rad Laboratories, Inc. Chemiluminescent hemoglobin assay
US6174734B1 (en) * 1997-10-24 2001-01-16 Abbott Laboratories Measurement of glycated hemoglobin
US6835545B2 (en) * 2000-05-08 2004-12-28 President And Fellows Of Harvard College Methods, products and treatments for diabetes
US7439330B2 (en) * 2000-05-08 2008-10-21 President And Fellows Of Harvard College Anti-glycated CD59 antibodies and uses thereof
CA2412994A1 (en) * 2000-06-30 2002-12-27 Kyowa Medex Co., Ltd. Insoluble carrier particle nephelometric immunoassay reagent
EP1304571A4 (en) * 2000-07-27 2007-06-27 Kyowa Medex Co Ltd IMMUNOLOGICAL ANALYSIS USING INSOLUBLE SUPPORT PARTICLES AND REACTIVE THEREFOR
CN2445326Y (zh) * 2000-10-09 2001-08-29 刘永详 测定被糖化蛋白的免疫分析装置
DE60212840T2 (de) * 2001-05-18 2007-02-01 SRL, Inc., Tachikawa Immunassayverfahren
US7659107B2 (en) * 2003-09-23 2010-02-09 Epinex Diagnostics, Inc. Rapid test for glycated albumin
DE102004052628A1 (de) * 2004-10-29 2006-05-04 Disetronic Licensing Ag Füllung bzw. Wiederauffüllung eines Injektions- oder Infusionsfluid aufnehmenden Behältnisses
ATE520029T1 (de) 2004-11-05 2011-08-15 Hoffmann La Roche Biochemisches gerät und nachweisverfahren
EP1825267A4 (en) * 2004-11-29 2008-07-09 Perkinelmer Life & Analytical Sciences MUTLIPLEX ASSAY ON PARTICLE BASE FOR GLYCOSYLATION IDENTIFICATION
WO2006086098A2 (en) * 2005-01-06 2006-08-17 President And Fellows Of Harvard College Mass spectrometric methods and products
WO2007077579A1 (en) * 2006-01-04 2007-07-12 Jawaharlal Nehru University A novelprocess for detecting human haemoglobin variants
ATE555386T1 (de) * 2007-10-30 2012-05-15 Panasonic Corp Verfahren zur messung von hämoglobin und hämoglobin-derivat sowie messkit
EP2357199A4 (en) 2008-12-11 2013-02-20 Sekisui Medical Co Ltd ANTIBODIES TO N-TERMINUS OF THE β-CHAIN OF HEMOGLOBIN
WO2010067612A1 (ja) * 2008-12-11 2010-06-17 積水メディカル株式会社 糖化ヘモグロビン含有試料の前処理法
US20100167306A1 (en) * 2008-12-26 2010-07-01 Henry John Smith Rapid test for glycated albumin in saliva
US9068006B2 (en) 2010-08-25 2015-06-30 President And Fellows Of Harvard College Glycated CD59 peptides, their preparation, and uses thereof
CN102914656B (zh) * 2012-07-23 2014-10-29 四川新健康成生物股份有限公司 间接免疫法糖化血清白蛋白检测试剂盒
JP6304231B2 (ja) * 2013-03-01 2018-04-04 富士レビオ株式会社 未感作ラテックス試薬の劣化防止方法
KR101701885B1 (ko) * 2015-01-21 2017-02-02 광주과학기술원 업컨버팅 나노입자 및 특이적 리셉터를 포함하는 당뇨병 진단용 복합체
CN105137082A (zh) * 2015-07-31 2015-12-09 柏荣诊断产品（上海）有限公司 一种双试剂糖化血红蛋白检测试剂盒
EP3726215A4 (en) 2017-12-12 2022-01-19 DxGen Corp. SILICA NANOPARTICLES FOR DIAGNOSIS BY BIOMARKERS AND PROCESS FOR THEIR PRODUCTION
CN108287245B (zh) * 2018-01-31 2021-03-16 迈克生物股份有限公司 测定糖化血红蛋白的试剂盒及其制备方法
CN115508568A (zh) * 2019-01-29 2022-12-23 美国西门子医学诊断股份有限公司 降低血红蛋白A1c测定中的英脱利匹特/脂血干扰的浊度归一化算法和方法
CN110514848B (zh) * 2019-08-21 2022-11-08 深圳上泰生物工程有限公司 一种糖化血红蛋白抗体复合物和糖化血红蛋白检测试剂盒
CN111157747A (zh) * 2020-01-17 2020-05-15 上海高踪医疗器械科技有限公司 一种糖化血红蛋白检测试剂盒及其生产工艺
CN112034186A (zh) * 2020-09-07 2020-12-04 南京立顶医疗科技有限公司 一种基于生物素-链霉亲和素放大的糖化血红蛋白试剂盒及其制备方法
CN117384281B (zh) * 2022-07-05 2024-04-26 东莞市朋志生物科技有限公司 抗糖化血红蛋白抗体、检测糖化血红蛋白的试剂和试剂盒

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0062968B2 (en) * 1981-03-18 1991-07-10 FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. Support material for use in serological testing and process for the production thereof
US4658022A (en) * 1985-08-08 1987-04-14 Molecular Diagnostics, Inc. Binding of antibody reagents to denatured protein analytes
US4727036A (en) * 1985-08-08 1988-02-23 Molecular Diagnostics, Inc. Antibodies for use in determining hemoglobin A1c
US4647654A (en) * 1984-10-29 1987-03-03 Molecular Diagnostics, Inc. Peptides useful in preparing hemoglobin A1c immunogens
DK145385D0 (da) * 1985-03-29 1985-04-01 Novo Industri As Monoklonalt antistof til immunkemisk analyse
US4806468A (en) * 1987-02-05 1989-02-21 Becton, Dickinson And Company Measurement of glycosylated hemoglobin by immunoassay
US4861728A (en) * 1987-07-24 1989-08-29 Becton, Dickinson And Company Immunoassay of glycosylated hemoglobin using a labeled boron reagent
US4847209A (en) * 1987-11-09 1989-07-11 Miles Inc. Latex agglutination immunoassay in the presence of hemoglobin
DE3806198A1 (de) * 1988-02-04 1989-08-17 Boehringer Mannheim Gmbh Immunogen und seine verwendung zur gewinnung von antikoerpern gegen hba(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)c(pfeil abwaerts)
US5183739A (en) * 1990-02-27 1993-02-02 Exocell, Inc. Monoclonal antibodies specific for non-a1c glycated hemoglobin and immunoassay methods

Also Published As

Publication number Publication date
EP0573972B1 (en) 2000-04-05
ES2146595T3 (es) 2000-08-16
DE69330649T2 (de) 2002-07-04
EP0864865B1 (en) 2001-08-22
US5470759A (en) 1995-11-28
EP0864865A2 (en) 1998-09-16
DE69330649D1 (de) 2001-09-27
EP0573972A2 (en) 1993-12-15
EP0864865A3 (en) 1998-10-21
DE69328273T2 (de) 2000-09-28
KR100292136B1 (ko) 2001-06-01
KR100257985B1 (ko) 2001-03-02
KR940005957A (ko) 1994-03-22
EP0573972A3 (es) 1994-02-02
DE69328273D1 (de) 2000-05-11

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