ES2155585T3 - Nuevos compuestos tetraciclicos de la 1,4-oxazina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. - Google Patents
Nuevos compuestos tetraciclicos de la 1,4-oxazina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.Info
- Publication number
- ES2155585T3 ES2155585T3 ES96402366T ES96402366T ES2155585T3 ES 2155585 T3 ES2155585 T3 ES 2155585T3 ES 96402366 T ES96402366 T ES 96402366T ES 96402366 T ES96402366 T ES 96402366T ES 2155585 T3 ES2155585 T3 ES 2155585T3
- Authority
- ES
- Spain
- Prior art keywords
- oxazine
- new
- tetraciclic
- compounds
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
NUEVOS COMPUESTOS TETRACICLICOS DE 1,4-OXACINA DE FORMULA: EN LA QUE -A-D-E- REPRESENTA, EN LOS QUE P REPRESENTA 2 O 3 Y M REPRESENTA CERO, 1 O 2, X REPRESENTA CH{SUB,2} Y ADEMAS, CUANDO A-D-E- REPRESENTA, X PUEDE TAMBIEN PUEDE REPRESENTAR UN ATOMO DE OXIGENO. ESTAS SUSTANCIAS EJERCEN SU ACCION EN EL REACTOR DOPAMINERGICO D{SUB,2} AL QUE ESTAN UNIDAS MUY FUERTEMENTE. ASI, SE PUEDEN UTILIZAR, CUANDO SON BLOQUEADORES DE ESTE RECEPTOR D{SUB,2}, EN EL TRATAMIENTO DE LA SICOFRENIA, Y CUANDO SON ACTIVADORES DE ESTE MISMO RECEPTOR, EN EL TRATAMIENTO DE LA ENFERMEDAD DE PARKINSON.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9513270A FR2741074B1 (fr) | 1995-11-09 | 1995-11-09 | Nouveaux composes tetracycliques de la 1,4-oxazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2155585T3 true ES2155585T3 (es) | 2001-05-16 |
Family
ID=9484393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96402366T Expired - Lifetime ES2155585T3 (es) | 1995-11-09 | 1996-11-07 | Nuevos compuestos tetraciclicos de la 1,4-oxazina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. |
Country Status (15)
Country | Link |
---|---|
US (1) | US5733908A (es) |
EP (1) | EP0773223B1 (es) |
JP (1) | JPH09169770A (es) |
CN (1) | CN1059443C (es) |
AT (1) | ATE198752T1 (es) |
AU (1) | AU709192B2 (es) |
CA (1) | CA2189731C (es) |
DE (1) | DE69611594T2 (es) |
ES (1) | ES2155585T3 (es) |
FR (1) | FR2741074B1 (es) |
GR (1) | GR3035432T3 (es) |
NO (1) | NO308132B1 (es) |
NZ (1) | NZ299725A (es) |
PT (1) | PT773223E (es) |
ZA (1) | ZA969412B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
ATE316969T1 (de) | 1998-10-08 | 2006-02-15 | Smithkline Beecham Plc | Tetrahydrobenzazepin-derivate verwendbar als dopamin-d3-rezeptor-modulatoren (antipsychotische mittel) |
EP1620083A2 (en) * | 2003-04-18 | 2006-02-01 | Pharmacia & Upjohn Company LLC | Combination therapies |
FR2906249B1 (fr) * | 2006-09-26 | 2008-12-19 | Servier Lab | Composes tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3583307D1 (en) | 1984-05-10 | 1991-08-01 | Ciba Geigy Ag | Benzo-(pyrano und thiopyrano)-pyridine. |
US4792548A (en) * | 1986-05-21 | 1988-12-20 | Warner-Lambert Company | Trans-benzopyran-(4,3-b)-1,4-oxazine derivatives, intermediates and pharmaceutical use |
WO1993024471A1 (en) | 1992-06-02 | 1993-12-09 | Whitby Research, Inc. | Substituted naphthoxazines useful as dopaminergics |
WO1994022495A1 (en) * | 1993-03-31 | 1994-10-13 | The Trustees Of The University Of Pennsylvania | Dopamine d-3 and serotonin (5-ht1a) receptor ligands and imaging agents |
FR2721027B1 (fr) * | 1994-06-08 | 1996-07-19 | Adir | Nouveaux dérivés tétracycliques de la 1,4-oxazine, leur procédé de préparation et les compositions pharmaceutiques les contenant. |
-
1995
- 1995-11-09 FR FR9513270A patent/FR2741074B1/fr not_active Expired - Fee Related
-
1996
- 1996-11-05 NO NO964672A patent/NO308132B1/no unknown
- 1996-11-06 CA CA002189731A patent/CA2189731C/fr not_active Expired - Fee Related
- 1996-11-07 AU AU71704/96A patent/AU709192B2/en not_active Ceased
- 1996-11-07 DE DE69611594T patent/DE69611594T2/de not_active Expired - Fee Related
- 1996-11-07 AT AT96402366T patent/ATE198752T1/de not_active IP Right Cessation
- 1996-11-07 PT PT96402366T patent/PT773223E/pt unknown
- 1996-11-07 ES ES96402366T patent/ES2155585T3/es not_active Expired - Lifetime
- 1996-11-07 EP EP96402366A patent/EP0773223B1/fr not_active Expired - Lifetime
- 1996-11-07 JP JP8295025A patent/JPH09169770A/ja active Pending
- 1996-11-08 US US08/745,212 patent/US5733908A/en not_active Expired - Fee Related
- 1996-11-08 CN CN96114534A patent/CN1059443C/zh not_active Expired - Fee Related
- 1996-11-08 ZA ZA969412A patent/ZA969412B/xx unknown
- 1996-11-08 NZ NZ299725A patent/NZ299725A/en unknown
-
2001
- 2001-02-20 GR GR20010400263T patent/GR3035432T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0773223B1 (fr) | 2001-01-17 |
NO308132B1 (no) | 2000-07-31 |
FR2741074A1 (fr) | 1997-05-16 |
FR2741074B1 (fr) | 1997-12-19 |
ATE198752T1 (de) | 2001-02-15 |
EP0773223A1 (fr) | 1997-05-14 |
CN1059443C (zh) | 2000-12-13 |
CN1156147A (zh) | 1997-08-06 |
US5733908A (en) | 1998-03-31 |
AU709192B2 (en) | 1999-08-26 |
PT773223E (pt) | 2001-06-29 |
NO964672L (no) | 1997-05-12 |
DE69611594D1 (de) | 2001-02-22 |
NZ299725A (en) | 1997-11-24 |
DE69611594T2 (de) | 2001-08-09 |
JPH09169770A (ja) | 1997-06-30 |
CA2189731A1 (fr) | 1997-05-10 |
CA2189731C (fr) | 2002-04-09 |
AU7170496A (en) | 1997-05-15 |
NO964672D0 (no) | 1996-11-05 |
ZA969412B (en) | 1997-06-02 |
GR3035432T3 (en) | 2001-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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