ES2068011T3 - Nuevos derivados de benzoato de etanol-amina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. - Google Patents

Nuevos derivados de benzoato de etanol-amina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Info

Publication number
ES2068011T3
ES2068011T3 ES92401620T ES92401620T ES2068011T3 ES 2068011 T3 ES2068011 T3 ES 2068011T3 ES 92401620 T ES92401620 T ES 92401620T ES 92401620 T ES92401620 T ES 92401620T ES 2068011 T3 ES2068011 T3 ES 2068011T3
Authority
ES
Spain
Prior art keywords
ethanol
pharmaceutical compositions
compositions containing
preparation procedure
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92401620T
Other languages
English (en)
Inventor
Michel Wierzbicki
Pierre Hugon
Jacques Duhault
Francoise Lacour
Michelle Boulanger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of ES2068011T3 publication Critical patent/ES2068011T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/14—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

NUEVOS DERIVADOS DE BENZOATO, UTILIZABLES COMO MEDICAMENTOS Y QUE RESPONDEN A LA FORMULA (I): EN LA QUE R ES TAL COMO SE DEFINE EN LA DESCRIPCION, BAJO FORMAS RACEMICAS Y ENANTIOMERAS. ESTOS NUEVOS COMPUESTOS Y SUS SALES FISIOLOGICAMENTE TOLERABLES PUEDEN SER UTILIZADOS EN TERAPIA.
ES92401620T 1991-06-14 1992-06-12 Nuevos derivados de benzoato de etanol-amina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. Expired - Lifetime ES2068011T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9107289A FR2677647B1 (fr) 1991-06-14 1991-06-14 Nouveaux derives de benzoate d'ethanolamine, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Publications (1)

Publication Number Publication Date
ES2068011T3 true ES2068011T3 (es) 1995-04-01

Family

ID=9413849

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92401620T Expired - Lifetime ES2068011T3 (es) 1991-06-14 1992-06-12 Nuevos derivados de benzoato de etanol-amina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Country Status (14)

Country Link
EP (1) EP0518769B1 (es)
JP (1) JPH0669995B2 (es)
AT (1) ATE115118T1 (es)
AU (1) AU646958B2 (es)
CA (1) CA2071093C (es)
DE (1) DE69200810T2 (es)
DK (1) DK0518769T3 (es)
ES (1) ES2068011T3 (es)
FR (1) FR2677647B1 (es)
GR (1) GR3015212T3 (es)
HK (1) HK56797A (es)
IE (1) IE65634B1 (es)
NZ (1) NZ243116A (es)
ZA (1) ZA924312B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003013605A1 (fr) * 2001-08-07 2003-02-20 Japan Tobacco, Inc. Remedes pour maladies prostatiques
FR2834891B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible de 2-({2-methoxy-2-[3(trifluoromethyl)phenyl]ethyl}amino)ethyl4 -(2-(9h-fluoren-9-yl)acetyl]amino}ethyl)benzoate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE320982B (es) * 1965-06-28 1970-02-23 Melville Sahyun Doing Business
GB1162070A (en) * 1967-06-12 1969-08-20 Science Union & Cie New Sulphamyl Benzoic Acid Derivatives and processes for preparing them
DE2629752A1 (de) * 1976-07-02 1978-01-05 Boehringer Mannheim Gmbh Neue carbonsaeurederivate und verfahren zu ihrer herstellung
US4237165A (en) * 1976-06-04 1980-12-02 Science Union Et Cie Treatment of carbohydrate metabolism disorders
DE3260490D1 (en) * 1981-03-31 1984-09-06 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
FR2684101B1 (fr) * 1991-11-22 1993-12-31 Adir Cie Nouveaux derives de benzoate d'ethanolamine, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Also Published As

Publication number Publication date
ZA924312B (en) 1993-03-31
IE921903A1 (en) 1992-12-16
HK56797A (en) 1997-05-09
FR2677647B1 (fr) 1993-08-20
EP0518769B1 (fr) 1994-12-07
CA2071093C (fr) 1998-08-04
DE69200810T2 (de) 1995-07-06
DK0518769T3 (da) 1995-05-29
GR3015212T3 (en) 1995-05-31
JPH0669995B2 (ja) 1994-09-07
AU646958B2 (en) 1994-03-10
IE65634B1 (en) 1995-11-01
EP0518769A1 (fr) 1992-12-16
FR2677647A1 (fr) 1992-12-18
DE69200810D1 (de) 1995-01-19
JPH05238997A (ja) 1993-09-17
ATE115118T1 (de) 1994-12-15
AU1821092A (en) 1992-12-17
NZ243116A (en) 1993-07-27
CA2071093A1 (fr) 1992-12-15

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