ES2126616T3 - Vacuna pediatrica combinada, con una inmunogenecidad aumentada de cada componente de la vacuna. - Google Patents

Vacuna pediatrica combinada, con una inmunogenecidad aumentada de cada componente de la vacuna.

Info

Publication number
ES2126616T3
ES2126616T3 ES93111735T ES93111735T ES2126616T3 ES 2126616 T3 ES2126616 T3 ES 2126616T3 ES 93111735 T ES93111735 T ES 93111735T ES 93111735 T ES93111735 T ES 93111735T ES 2126616 T3 ES2126616 T3 ES 2126616T3
Authority
ES
Spain
Prior art keywords
vaccine
combined
component
increased immunogenicity
vaccine composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93111735T
Other languages
English (en)
Inventor
Peter R Paradiso
Deborah A Hogerman
Dace Viceps Madore
Jill G Hackell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2126616T3 publication Critical patent/ES2126616T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Peptides Or Proteins (AREA)

Abstract

SE PRESENTA UNA COMPOSICION DE VACUNA PEDIATRICA COMBINADA QUE SE CARACTERIZA, EN UNA DOSIS DE INMUNIZACION UNICA, UNA MEZCLA DE ANTIGENO DE PERTUSIS TETANOS Y DIFTERIA Y UN CONJUGADO DE FRAGMENTOS DEL ANTIGENO DE POLISACARIDO CAPSULAR DE HAEMOPHILUS INFLUENZAE DE TIPO B Y PROTEINA CRB-97 EN UN VEHICULO ACUOSO FARMACEUTICAMENTE ACEPTABLE. LA COMPOSICION DE VACUNA COMBINADA EXHIBE UNA RESPUESTA DE ANTICUERPOS REALZADA POR NIÑO A CADA UNO DE LOS 4 COMPONENTES DE VACUNA.
ES93111735T 1992-10-27 1993-07-22 Vacuna pediatrica combinada, con una inmunogenecidad aumentada de cada componente de la vacuna. Expired - Lifetime ES2126616T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96699592A 1992-10-27 1992-10-27

Publications (1)

Publication Number Publication Date
ES2126616T3 true ES2126616T3 (es) 1999-04-01

Family

ID=25512167

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93111735T Expired - Lifetime ES2126616T3 (es) 1992-10-27 1993-07-22 Vacuna pediatrica combinada, con una inmunogenecidad aumentada de cada componente de la vacuna.

Country Status (23)

Country Link
EP (1) EP0594950B1 (es)
JP (1) JPH07300427A (es)
KR (1) KR100289224B1 (es)
AT (1) ATE176157T1 (es)
AU (1) AU669570B2 (es)
CA (1) CA2109159A1 (es)
CZ (1) CZ283587B6 (es)
DE (2) DE69323264D1 (es)
DK (1) DK0594950T3 (es)
ES (1) ES2126616T3 (es)
FI (1) FI934725A (es)
GR (1) GR3029884T3 (es)
HK (1) HK1009931A1 (es)
HU (1) HU215149B (es)
IL (1) IL107387A (es)
LV (1) LV12271B (es)
NO (1) NO308588B1 (es)
NZ (1) NZ250029A (es)
PL (1) PL174130B1 (es)
RU (1) RU2121365C1 (es)
SG (1) SG47725A1 (es)
TW (1) TW256774B (es)
UA (1) UA27754C2 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1864195A (en) * 1994-03-07 1995-09-25 Auckland Uniservices Limited Prevention of diabetes
CA2222455C (en) * 1995-03-22 2013-05-28 Smithkline Beecham Biologicals S.A. A vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate
BR9608612A (pt) * 1995-06-07 1999-05-04 Smithkline Beecham Biolog Vacina compreendendo um conjugado de antígeno de polissacarídeo - proteína portadora e proteína portadora livre
US20020054884A1 (en) 1995-06-23 2002-05-09 Smithkline Beecham Biologicals, Sa Vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate
EP1762246A1 (en) * 1996-07-02 2007-03-14 Sanofi Pasteur Limited Multivalent DTP-Polio vaccines
PT1296715E (pt) * 2000-06-29 2012-01-19 Smithkline Beecham Biolog Composição vacinal multivalente
GB0108364D0 (en) * 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
ES2649048T3 (es) 2002-11-01 2018-01-09 Glaxosmithkline Biologicals S.A. Procedimiento de secado
GB0505996D0 (en) * 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
KR101408113B1 (ko) 2005-06-27 2014-06-16 글락소스미스클라인 바이오로지칼즈 에스.에이. 백신 제조 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4902506A (en) * 1983-07-05 1990-02-20 The University Of Rochester Immunogenic conjugates

Also Published As

Publication number Publication date
LV12271A (lv) 1999-05-20
HK1009931A1 (en) 1999-06-11
DE69323264T4 (de) 1999-10-14
CZ227293A3 (en) 1994-05-18
AU5029093A (en) 1994-05-12
FI934725A (fi) 1994-04-28
ATE176157T1 (de) 1999-02-15
RU2121365C1 (ru) 1998-11-10
NZ250029A (en) 1994-09-27
EP0594950B1 (en) 1999-01-27
HUT67239A (en) 1995-03-28
KR940008698A (ko) 1994-05-16
AU669570B2 (en) 1996-06-13
UA27754C2 (uk) 2000-10-16
JPH07300427A (ja) 1995-11-14
NO933856D0 (no) 1993-10-26
PL174130B1 (pl) 1998-06-30
LV12271B (en) 1999-07-20
CA2109159A1 (en) 1994-04-28
IL107387A0 (en) 1994-01-25
HU9303028D0 (en) 1994-01-28
FI934725A0 (fi) 1993-10-26
NO308588B1 (no) 2000-10-02
CZ283587B6 (cs) 1998-05-13
SG47725A1 (en) 1998-04-17
HU215149B (hu) 2000-03-28
GR3029884T3 (en) 1999-07-30
KR100289224B1 (ko) 2001-05-02
DE69323264D1 (de) 1999-03-11
TW256774B (es) 1995-09-11
DK0594950T3 (da) 1999-09-13
EP0594950A1 (en) 1994-05-04
IL107387A (en) 1997-04-15
NO933856L (no) 1994-04-28
DE69323264T2 (de) 1999-06-02

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