ES2116522T3 - Compuestos citotoxicos. - Google Patents
Compuestos citotoxicos.Info
- Publication number
- ES2116522T3 ES2116522T3 ES94300778T ES94300778T ES2116522T3 ES 2116522 T3 ES2116522 T3 ES 2116522T3 ES 94300778 T ES94300778 T ES 94300778T ES 94300778 T ES94300778 T ES 94300778T ES 2116522 T3 ES2116522 T3 ES 2116522T3
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- cytotoxic compounds
- mpta
- antitumoral
- presented
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 231100000433 cytotoxic Toxicity 0.000 title 1
- 230000001472 cytotoxic effect Effects 0.000 title 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/11—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/02—1,2-Dioxanes; Hydrogenated 1,2-dioxanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cephalosporin Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
SE PRESENTAN COMPUESTOS AISLADOS A PARTIR DE UNA ESPONJA MARINA Y DERIVADOS DE LOS MISMOS QUE TIENEN LAS FORMULAS (I) Y (II) EN DONDE R1 ES H O ALQUILO INFERIOR; R2 ES OH O CH3; R3 ES OH O CH3, Y R4 ES H O MPTA. LOS COMPUESTOS TIENEN ACTIVIDAD ANTITUMORAL Y ANTIVIRAL. LA INVENCION TAMBIEN SE REFIERE A COMPOSICIONES FARMACEUTICAS QUE CONTIENEN LOS COMPUESTOS Y A METODOS DE TRATAMIENTO QUE LOS EMPLEAN.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939302044A GB9302044D0 (en) | 1993-02-03 | 1993-02-03 | Cytotoxic compounds i |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2116522T3 true ES2116522T3 (es) | 1998-07-16 |
Family
ID=10729726
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94300778T Expired - Lifetime ES2116522T3 (es) | 1993-02-03 | 1994-02-02 | Compuestos citotoxicos. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5449684A (es) |
EP (1) | EP0610076B1 (es) |
JP (1) | JPH0769884A (es) |
AT (1) | ATE165094T1 (es) |
AU (1) | AU674366B2 (es) |
CA (1) | CA2114777A1 (es) |
DE (1) | DE69409553T2 (es) |
DK (1) | DK0610076T3 (es) |
ES (1) | ES2116522T3 (es) |
GB (1) | GB9302044D0 (es) |
ZA (1) | ZA94746B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6541515B2 (en) * | 2000-08-09 | 2003-04-01 | Merck & Co., Inc. | HIV integrase inhibitors |
JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4731377A (en) * | 1986-01-31 | 1988-03-15 | Harbor Branch Oceanographic Institute, Inc. | Antitumor cyclic peroxides |
US5183924A (en) * | 1989-01-24 | 1993-02-02 | Lipha, Lyonnaise Industrielle Pharmaceutique | Derivatives of benzocycloalkenyldihydroxyalkanoic acids, processes of preparation and medications containing them |
-
1993
- 1993-02-03 GB GB939302044A patent/GB9302044D0/en active Pending
-
1994
- 1994-02-02 AT AT94300778T patent/ATE165094T1/de not_active IP Right Cessation
- 1994-02-02 DK DK94300778T patent/DK0610076T3/da active
- 1994-02-02 DE DE69409553T patent/DE69409553T2/de not_active Expired - Fee Related
- 1994-02-02 CA CA002114777A patent/CA2114777A1/en not_active Abandoned
- 1994-02-02 EP EP94300778A patent/EP0610076B1/en not_active Expired - Lifetime
- 1994-02-02 ES ES94300778T patent/ES2116522T3/es not_active Expired - Lifetime
- 1994-02-03 US US08/191,336 patent/US5449684A/en not_active Expired - Fee Related
- 1994-02-03 ZA ZA94746A patent/ZA94746B/xx unknown
- 1994-02-03 JP JP6043023A patent/JPH0769884A/ja active Pending
- 1994-02-03 AU AU54910/94A patent/AU674366B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP0610076B1 (en) | 1998-04-15 |
AU5491094A (en) | 1994-08-11 |
DE69409553D1 (de) | 1998-05-20 |
AU674366B2 (en) | 1996-12-19 |
JPH0769884A (ja) | 1995-03-14 |
EP0610076A1 (en) | 1994-08-10 |
GB9302044D0 (en) | 1993-03-24 |
US5449684A (en) | 1995-09-12 |
CA2114777A1 (en) | 1994-08-04 |
ZA94746B (en) | 1994-09-29 |
DK0610076T3 (da) | 1999-01-25 |
ATE165094T1 (de) | 1998-05-15 |
DE69409553T2 (de) | 1998-10-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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