ES2104090T3 - Nuevas 3',5'-di-t-butil-4'-hidroxi-flavonas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen. - Google Patents
Nuevas 3',5'-di-t-butil-4'-hidroxi-flavonas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.Info
- Publication number
- ES2104090T3 ES2104090T3 ES93400811T ES93400811T ES2104090T3 ES 2104090 T3 ES2104090 T3 ES 2104090T3 ES 93400811 T ES93400811 T ES 93400811T ES 93400811 T ES93400811 T ES 93400811T ES 2104090 T3 ES2104090 T3 ES 2104090T3
- Authority
- ES
- Spain
- Prior art keywords
- flavonas
- hidroxi
- butil
- contain
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
COMPUESTOS DE FORMULA GENERAL (I): EN LA QUE R REPRESENTA: AL COMO SE DEFINE EN LA DESCRIPCION. MEDICAMENTOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9203861A FR2689127B1 (fr) | 1992-03-31 | 1992-03-31 | Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2104090T3 true ES2104090T3 (es) | 1997-10-01 |
Family
ID=9428265
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93400811T Expired - Lifetime ES2104090T3 (es) | 1992-03-31 | 1993-03-30 | Nuevas 3',5'-di-t-butil-4'-hidroxi-flavonas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen. |
Country Status (13)
Country | Link |
---|---|
US (2) | US5280024A (es) |
EP (1) | EP0564350B1 (es) |
JP (1) | JPH07119221B2 (es) |
AT (1) | ATE153022T1 (es) |
AU (1) | AU655106B2 (es) |
CA (1) | CA2092961A1 (es) |
DE (1) | DE69310602T2 (es) |
DK (1) | DK0564350T3 (es) |
ES (1) | ES2104090T3 (es) |
FR (1) | FR2689127B1 (es) |
GR (1) | GR3023938T3 (es) |
NZ (1) | NZ247287A (es) |
ZA (1) | ZA932312B (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2689127B1 (fr) * | 1992-03-31 | 1994-05-06 | Adir Cie | Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
AU5259296A (en) * | 1995-04-07 | 1996-10-23 | Warner-Lambert Company | Flavones and coumarins as agents for the treatment of athero sclerosis |
DE19638515B4 (de) * | 1996-09-20 | 2004-01-15 | Grundig Car Intermedia System Gmbh | Verfahren und Vorrichtung zur Zuordnung von Nachrichten, insbesondere Verkehrsnachrichten |
FR2753969B1 (fr) * | 1996-09-27 | 1998-10-30 | Adir | Nouveaux derives de flavones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6207665B1 (en) | 1997-06-12 | 2001-03-27 | Schering Aktiengesellschaft | Piperazine derivatives and their use as anti-inflammatory agents |
US6028088A (en) * | 1998-10-30 | 2000-02-22 | The University Of Mississippi | Flavonoid derivatives |
EP1127572A3 (en) * | 2000-02-25 | 2003-05-02 | Basf Aktiengesellschaft | Use of flavones for treating cycloxygenase-2 mediated diseases |
FR2815033B1 (fr) | 2000-10-06 | 2003-09-05 | Negma Lab | Derives de 7-carboxy-flavones, porcede pour leur preparation et leur application en therapeutique |
US6818668B2 (en) | 2002-04-12 | 2004-11-16 | Biotest Laboratories, Llc | 5-alkyl-7-alkylcarbonate-isoflavone ester and related method |
GB0216371D0 (en) | 2002-07-13 | 2002-08-21 | Rowett Res Inst The | Compounds |
DE10232595A1 (de) * | 2002-07-18 | 2004-02-05 | Merck Patent Gmbh | Lichtschutzmittel |
WO2006045096A2 (en) | 2004-10-20 | 2006-04-27 | Resverlogix Corp. | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases |
KR100729731B1 (ko) * | 2005-07-19 | 2007-06-20 | 건국대학교 산학협력단 | 사람 피부 세포의 세포사멸을 억제하는 활성을 갖는플라보노이드 |
AU2006275514B2 (en) * | 2005-07-29 | 2012-04-05 | Resverlogix Corp. | Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices |
US8053440B2 (en) | 2007-02-01 | 2011-11-08 | Resverlogix Corporation | Compounds for the prevention and treatment of cardiovascular diseases |
CA2711103C (en) | 2008-06-26 | 2016-08-09 | Resverlogix Corp. | Methods of preparing quinazolinone derivatives |
EP2382194B1 (en) | 2009-01-08 | 2014-03-12 | Resverlogix Corp. | Compounds for the prevention and treatment of cardiovascular disease |
JP5795304B2 (ja) | 2009-03-18 | 2015-10-14 | レスバーロジックス コーポレイション | 新規抗炎症剤 |
KR101892987B1 (ko) | 2009-04-22 | 2018-08-30 | 리스버로직스 코퍼레이션 | 신규한 소염제 |
GB201017315D0 (en) | 2010-10-13 | 2010-11-24 | Antoxis Ltd | Compound |
DK2773354T3 (da) | 2011-11-01 | 2019-08-05 | Resverlogix Corp | Oralformuleringer med øjeblikkelig frigivelse for substituerede quinazolinoner |
WO2014080290A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Cyclic amines as bromodomain inhibitors |
WO2014080291A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Biaryl derivatives as bromodomain inhibitors |
AU2013365926B9 (en) | 2012-12-21 | 2019-01-17 | Zenith Epigenetics Ltd. | Novel heterocyclic compounds as bromodomain inhibitors |
KR102662814B1 (ko) | 2015-03-13 | 2024-05-03 | 리스버로직스 코퍼레이션 | 보체 관련 질환을 치료하기 위한 조성물 및 치료 방법 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1247909A (fr) * | 1955-11-02 | 1960-12-09 | Recordati Lab Farmacologico Dr | Procédé de préparation des dérivés d'hydroxychromones |
DE1054091B (de) * | 1958-05-30 | 1959-04-02 | Chemiewerk Homburg Ag | Verfahren zur Herstellung von N-substituierten 2-Phenyl-7-aminoalkoxy-chromonen |
DE1418516A1 (de) * | 1959-07-28 | 1968-12-05 | Klosa Dipl Chem Dr Josef | Verfahren zur Herstellung von Flavon-7-oxyessigsaeureamiden |
GB1250388A (es) * | 1968-11-27 | 1971-10-20 | ||
DE2029658A1 (de) * | 1970-06-16 | 1971-12-23 | Boehnnger Mannheim GmbH, 6800 Mann heim Waldhof | 2 (4 Oxo-4H 1 benzopyran 7 yl) oxy isobutter saure Derivate und Verfahren zur Herstellung derselben |
US3816466A (en) * | 1971-12-22 | 1974-06-11 | Warner Lambert Co | Flavanoid ring systems |
JPH02214780A (ja) * | 1989-02-14 | 1990-08-27 | San Ei Chem Ind Ltd | アントシアン色素の安定化法 |
JPH035423A (ja) * | 1989-06-01 | 1991-01-11 | Ichimaru Pharcos Co Ltd | フラボノイド含有過酸化脂質生成抑制剤 |
US5247102A (en) * | 1990-04-06 | 1993-09-21 | Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. | Process for the preparation of substituted isoflavone derivative |
DE4011187A1 (de) * | 1990-04-06 | 1991-10-10 | Hoechst Ag | Substituierte 3-thia- bzw. 3-oxa-alkyl-flavone, verfahren zu ihrer herstellung, verwendung derselben, arzneimittel auf basis dieser verbindungen sowie zwischenprodukte |
HRP930210A2 (en) * | 1992-02-25 | 1995-06-30 | Recordati Chem Pharm | Heterobicyclic compounds and pharmaceutical preparations containing them |
FR2689127B1 (fr) * | 1992-03-31 | 1994-05-06 | Adir Cie | Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
-
1992
- 1992-03-31 FR FR9203861A patent/FR2689127B1/fr not_active Expired - Fee Related
-
1993
- 1993-03-25 US US08/036,814 patent/US5280024A/en not_active Expired - Fee Related
- 1993-03-30 NZ NZ247287A patent/NZ247287A/en unknown
- 1993-03-30 JP JP5072457A patent/JPH07119221B2/ja not_active Expired - Lifetime
- 1993-03-30 AU AU35591/93A patent/AU655106B2/en not_active Ceased
- 1993-03-30 CA CA002092961A patent/CA2092961A1/fr not_active Abandoned
- 1993-03-30 DE DE69310602T patent/DE69310602T2/de not_active Expired - Fee Related
- 1993-03-30 DK DK93400811.1T patent/DK0564350T3/da active
- 1993-03-30 EP EP93400811A patent/EP0564350B1/fr not_active Expired - Lifetime
- 1993-03-30 AT AT93400811T patent/ATE153022T1/de not_active IP Right Cessation
- 1993-03-30 ES ES93400811T patent/ES2104090T3/es not_active Expired - Lifetime
- 1993-03-31 ZA ZA932312A patent/ZA932312B/xx unknown
- 1993-08-18 US US08/108,333 patent/US5457103A/en not_active Expired - Fee Related
-
1997
- 1997-06-30 GR GR970401586T patent/GR3023938T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ZA932312B (en) | 1993-10-18 |
US5280024A (en) | 1994-01-18 |
DE69310602D1 (de) | 1997-06-19 |
ATE153022T1 (de) | 1997-05-15 |
JPH07119221B2 (ja) | 1995-12-20 |
DK0564350T3 (da) | 1997-12-15 |
NZ247287A (en) | 1994-08-26 |
AU655106B2 (en) | 1994-12-01 |
US5457103A (en) | 1995-10-10 |
EP0564350A1 (fr) | 1993-10-06 |
FR2689127A1 (fr) | 1993-10-01 |
JPH0625212A (ja) | 1994-02-01 |
DE69310602T2 (de) | 1997-12-18 |
AU3559193A (en) | 1993-10-07 |
CA2092961A1 (fr) | 1993-10-01 |
GR3023938T3 (en) | 1997-09-30 |
EP0564350B1 (fr) | 1997-05-14 |
FR2689127B1 (fr) | 1994-05-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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