ES2085863T3 - Dispositivo para muestreo iontoforetico no invasivo o para el suministro de substancias. - Google Patents

Dispositivo para muestreo iontoforetico no invasivo o para el suministro de substancias.

Info

Publication number
ES2085863T3
ES2085863T3 ES89300782T ES89300782T ES2085863T3 ES 2085863 T3 ES2085863 T3 ES 2085863T3 ES 89300782 T ES89300782 T ES 89300782T ES 89300782 T ES89300782 T ES 89300782T ES 2085863 T3 ES2085863 T3 ES 2085863T3
Authority
ES
Spain
Prior art keywords
skin
iontophoretical
invasive
substances
supply
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89300782T
Other languages
English (en)
Inventor
Peretz Glikfeld
Christopher Cullander
Robert S Hinz
Richard H Guy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Application granted granted Critical
Publication of ES2085863T3 publication Critical patent/ES2085863T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Optics & Photonics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electrotherapy Devices (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Seal Device For Vehicle (AREA)

Abstract

EL PRESENTE INVENTO SE REFIERE A UN DISPOSITIVO DE VITRO PARA LA EXTRACCION DE SUSTANCIAS IONIZADAS PROCEDENTES DE UNA MUESTRA DE MEMBRANA SIN PENETRACION MECANICA, CONSTANDO DICHO DISPOSITIVO DE: (A) UN ELECTRODO POSITIVO; (B) UN ELECTRODO NEGATIVO. Y (C) UN AISLAMIENTO ELECTRICO ENTRE UNA SUBPARTE (A) Y (B), ESTANDO EL ELECTRODO POSITIVO, EL ELECTRODO NEGATIVO Y EL AISLAMIENTO ELECTRICO POSICIONADOS EN EL MISMO LADO DE LA MUESTRA DE MEMBRANA. EL PRESENTE INVENTO SE REFIERE A UN DISPOSITIVO PARA LA EXTRACCION O SUMINISTRO DE SUSTANCIAS IONIZADAS A UN MAMIFERO A TRAVES DE LA PIEL O DE LA MEMBRANA DE LA MUCOSA SIN PENETRACION MECANICA, Y CONSTA DE: (A) UN ELECTRODO POSITIVO, (B) UN ELECTRODO NEGATIVO, Y (C) UN MATERIAL AISLANTE ELECTRICO ENTRE LA SUBPARTE (A) Y (B), ESTANDO EL ELECTRODO POSITIVO, EL ELECTRODO NEGATIVO Y EL MATERIAL AISLANTE FISICAMENTE POSICIONADOS DE FORMA QUE CADA UNO DE ELLOS PRESENTA UNA SUPERFICIE COMUN DEL DISPOSITIVO PARA CONTACTAR CON LA MISMA SUPERFICIE DE LAPIEL O MEMBRANA DE LA MUCOSA DEL MAMIFERO. EL PRESENTE INVENTO SE REFIERE ASIMISMO AL USO DE LA IONTOFORESIS PARA DETERMINAR EL NIVEL DE UNA MOLECULA CARGADA EN UN MAMIFERO VIVO, Y MEDIANTE EL USO DE UN MECANISMO DE RETROALIMENTACION, ADMINISTRAR LOS NIVELES ADECUADOS DE SUSTANCIAS TERAPEUTICAS.
ES89300782T 1988-01-29 1989-01-27 Dispositivo para muestreo iontoforetico no invasivo o para el suministro de substancias. Expired - Lifetime ES2085863T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15015988A 1988-01-29 1988-01-29
US29939789A 1989-01-24 1989-01-24

Publications (1)

Publication Number Publication Date
ES2085863T3 true ES2085863T3 (es) 1996-06-16

Family

ID=26847373

Family Applications (3)

Application Number Title Priority Date Filing Date
ES89300782T Expired - Lifetime ES2085863T3 (es) 1988-01-29 1989-01-27 Dispositivo para muestreo iontoforetico no invasivo o para el suministro de substancias.
ES95105321T Expired - Lifetime ES2188624T3 (es) 1988-01-29 1989-01-27 Dispositivo de muestreo.
ES01110555T Expired - Lifetime ES2213077T3 (es) 1988-01-29 1989-01-27 Dispositivo para controlar de manera substancialmente continua el nivel de un material bioactivo.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES95105321T Expired - Lifetime ES2188624T3 (es) 1988-01-29 1989-01-27 Dispositivo de muestreo.
ES01110555T Expired - Lifetime ES2213077T3 (es) 1988-01-29 1989-01-27 Dispositivo para controlar de manera substancialmente continua el nivel de un material bioactivo.

Country Status (11)

Country Link
US (1) US5279543A (es)
EP (3) EP1121896B1 (es)
JP (1) JP2907342B2 (es)
KR (1) KR970011449B1 (es)
AT (3) ATE129909T1 (es)
DE (3) DE68929447T2 (es)
DK (1) DK175443B1 (es)
ES (3) ES2085863T3 (es)
IE (1) IE63406B1 (es)
PT (1) PT89560B (es)
WO (1) WO1989006989A1 (es)

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DE68929447T2 (de) 2004-01-15
DK179390A (da) 1990-07-28
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EP0673622A2 (en) 1995-09-27
EP0326398A2 (en) 1989-08-02
DE68929447D1 (de) 2003-02-06
KR970011449B1 (ko) 1997-07-11
AU639888B2 (en) 1993-08-12
PT89560A (pt) 1989-11-10
WO1989006989A1 (en) 1989-08-10
ATE230283T1 (de) 2003-01-15
DE68929508D1 (de) 2004-01-29
EP0326398B1 (en) 1995-11-08
EP1121896B1 (en) 2003-12-17
JP2907342B2 (ja) 1999-06-21
EP0673622B1 (en) 2003-01-02
ES2213077T3 (es) 2004-08-16
ATE129909T1 (de) 1995-11-15
IE890285L (en) 1989-07-29
KR900700155A (ko) 1990-08-11
DE68924716D1 (de) 1995-12-14
JPH04502561A (ja) 1992-05-14
IE63406B1 (en) 1995-04-19
US5279543A (en) 1994-01-18
ATE256420T1 (de) 2004-01-15
DK175443B1 (da) 2004-10-25
DK179390D0 (da) 1990-07-27
DE68924716T2 (de) 1996-07-04
EP0673622A3 (es) 1995-11-08
EP1121896A1 (en) 2001-08-08
AU3183889A (en) 1989-08-25
PT89560B (pt) 1995-05-31
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