ES2077146T3 - Composiciones farmaceuticas rectales que contienen calcitonina liofilizada. - Google Patents
Composiciones farmaceuticas rectales que contienen calcitonina liofilizada.Info
- Publication number
- ES2077146T3 ES2077146T3 ES91120965T ES91120965T ES2077146T3 ES 2077146 T3 ES2077146 T3 ES 2077146T3 ES 91120965 T ES91120965 T ES 91120965T ES 91120965 T ES91120965 T ES 91120965T ES 2077146 T3 ES2077146 T3 ES 2077146T3
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical compositions
- calcitonin
- compositions containing
- containing lyophilized
- rectal pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 102000055006 Calcitonin Human genes 0.000 title 1
- 108060001064 Calcitonin Proteins 0.000 title 1
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 title 1
- 229960004015 calcitonin Drugs 0.000 title 1
- 239000004094 surface-active agent Substances 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000012062 aqueous buffer Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- BBBFJLBPOGFECG-UHFFFAOYSA-N salmon calcitonin Chemical compound C=1N=CNC=1CC(C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CC=1C=CC(O)=CC=1)C(=O)N1C(CCC1)C(=O)NC(CCCNC(N)=N)C(=O)NC(C(C)O)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(C)O)C(=O)N1C(CCC1)C(N)=O)NC(=O)C(CC(C)C)NC(=O)C(CCC(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(C(C)C)NC(=O)C1CSSCC(N)C(=O)NC(CO)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)N1 BBBFJLBPOGFECG-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
COMPOSICIONES FARMACEUTICAS RECTALES, EN FORMA DE SUPOSITORIOS, QUE CONTIENEN CALCITONINA COMO INGREDIENTE ACTIVO, SIENDO LIOFILIZADA DICHA CALCITONITA EN UN SOPORTE ADECUADO. PREFERIBLEMENTE, LAS COMPOSICIONES DE LA INVENCION TAMBIEN CONTIENEN UN TAMPON ACUOSO, QUE CONSISTE EN UNA SAL DE ADICION ACIDA ORGANICA DE TROMETAMINA, QUE TIENE PROPIEDADES SURFACTANTES Y PROMOTORAS DE LA ABSORCION; Y MAS AUXILIARES OPCIONALES TALES COMO SURFACTANTES, DISPERSANTES, ESTABILIZADORES, PORTADORES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM910188A IT1244500B (it) | 1991-03-21 | 1991-03-21 | Impiego di sali minerali di trometamina in composizioni farmaceutiche a base di calcitonina somministrabili per via rettale in terapia umana |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2077146T3 true ES2077146T3 (es) | 1995-11-16 |
Family
ID=11399989
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91120965T Expired - Lifetime ES2077146T3 (es) | 1991-03-21 | 1991-12-06 | Composiciones farmaceuticas rectales que contienen calcitonina liofilizada. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0504483B1 (es) |
AT (1) | ATE126064T1 (es) |
DE (1) | DE69112028T2 (es) |
ES (1) | ES2077146T3 (es) |
GR (1) | GR3017760T3 (es) |
IT (1) | IT1244500B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0776527A (ja) * | 1993-06-28 | 1995-03-20 | Hayashibara Biochem Lab Inc | 半固形製剤とその製造方法 |
DE726075T1 (de) * | 1995-02-08 | 1996-12-12 | Therapicon Srl | Nicht-inorganische pharmazeutische salzige Lösungen zur endonasale Verabreichung |
IT1298780B1 (it) * | 1998-03-24 | 2000-02-02 | Therapicon Srl | Preparazioni parenterali a base di calcitonina |
JP6378475B2 (ja) * | 2012-12-05 | 2018-08-22 | ミヨシ油脂株式会社 | 親水性室温イオン液体とその用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE460638B (sv) * | 1981-01-14 | 1989-11-06 | Toyo Jozo Kk | Suppositoriepreparat med foerbaettrad absorptionsegenskap |
US4774091A (en) * | 1983-10-14 | 1988-09-27 | Sumitomo Pharmaceuticals Company, Ltd. | Long-term sustained-release preparation |
JP2514249B2 (ja) * | 1989-05-23 | 1996-07-10 | 帝人株式会社 | 安定化されたカルシトニン類医薬組成物 |
-
1991
- 1991-03-21 IT ITRM910188A patent/IT1244500B/it active IP Right Grant
- 1991-12-06 AT AT91120965T patent/ATE126064T1/de not_active IP Right Cessation
- 1991-12-06 EP EP91120965A patent/EP0504483B1/en not_active Expired - Lifetime
- 1991-12-06 ES ES91120965T patent/ES2077146T3/es not_active Expired - Lifetime
- 1991-12-06 DE DE69112028T patent/DE69112028T2/de not_active Expired - Fee Related
-
1995
- 1995-10-18 GR GR950402860T patent/GR3017760T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ITRM910188A1 (it) | 1992-09-21 |
GR3017760T3 (en) | 1996-01-31 |
DE69112028T2 (de) | 1996-04-18 |
EP0504483A1 (en) | 1992-09-23 |
ATE126064T1 (de) | 1995-08-15 |
ITRM910188A0 (it) | 1991-03-21 |
DE69112028D1 (de) | 1995-09-14 |
IT1244500B (it) | 1994-07-15 |
EP0504483B1 (en) | 1995-08-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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