ES2069841T3 - Nuevos derivados de imidazo-(1,2-c)-quinazolina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. - Google Patents

Nuevos derivados de imidazo-(1,2-c)-quinazolina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Info

Publication number
ES2069841T3
ES2069841T3 ES91400645T ES91400645T ES2069841T3 ES 2069841 T3 ES2069841 T3 ES 2069841T3 ES 91400645 T ES91400645 T ES 91400645T ES 91400645 T ES91400645 T ES 91400645T ES 2069841 T3 ES2069841 T3 ES 2069841T3
Authority
ES
Spain
Prior art keywords
optionally substituted
imidazo
amino
hydrogen
quinazolina
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91400645T
Other languages
English (en)
Inventor
Jean-Jacques Bourguignon
Camille-Georges Wermuth
De La Faverie Jean-Fran Renaud
Catherine Thollon
Alain Lombet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of ES2069841T3 publication Critical patent/ES2069841T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

ABLES COMO MEDICAMENTOS Y QUE RESPONDEN A LA FORMULA: EN LA QUE: 6) EVENTUALMENTE SUSTITUIDO POR UN FENILO, EL MISMO EVENTUALMENTE SUSTITUIDO CICLOALQUILO (C SUB 3-C SUB 6), FENILO EVENTUALMENTE SUSTITUIDO, FURILO, TIENILO O ACILO. GENO, HALOGENO O ALQUILO (C SUB 1-C SUB 6) EVENTUALMENTE SUSTITUIDO POR AMINO O DIALQUILAMINO; LO (C SUB 1-C SUB 6) EVENTUALMENTE SUSTITUIDO POR UN ANILO, O R-CO-(CH SUB 2) SUB IN-[SIENDO N 1, 2, O 3 Y R ALCOXI C SUB 1-C SUB 6, AMINO, (ALQUILO O DIALQUIL) AMINO, MORFOLINO O METILPIPERAZNILO]; Y SUS SALES FISIOLOGICAMENTE TOLERABLES PUEDEN SER UTILIZADOS CON USO TERAPEUTICO.
ES91400645T 1990-03-09 1991-03-08 Nuevos derivados de imidazo-(1,2-c)-quinazolina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. Expired - Lifetime ES2069841T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9003003A FR2659329B1 (fr) 1990-03-09 1990-03-09 Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Publications (1)

Publication Number Publication Date
ES2069841T3 true ES2069841T3 (es) 1995-05-16

Family

ID=9394556

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91400645T Expired - Lifetime ES2069841T3 (es) 1990-03-09 1991-03-08 Nuevos derivados de imidazo-(1,2-c)-quinazolina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Country Status (16)

Country Link
US (1) US5128338A (es)
EP (1) EP0446141B1 (es)
JP (1) JPH07103122B2 (es)
AT (1) ATE117303T1 (es)
AU (1) AU633408B2 (es)
CA (1) CA2037812A1 (es)
DE (1) DE69106746T2 (es)
DK (1) DK0446141T3 (es)
ES (1) ES2069841T3 (es)
FR (1) FR2659329B1 (es)
GR (1) GR3015514T3 (es)
IE (1) IE66181B1 (es)
NZ (1) NZ237363A (es)
OA (1) OA09488A (es)
PT (1) PT96982A (es)
ZA (1) ZA911726B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK588489D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK588389D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5512677A (en) * 1991-08-13 1996-04-30 National Science Council 3-substituted methyl-2,3-dihydroimidazo 1,2-c!quinazoline derivatives, the preparation and use thereof
US5158953A (en) * 1991-08-13 1992-10-27 National Science Council 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof
US5212310A (en) * 1991-12-19 1993-05-18 Neurogen Corporation Certain aryl fused imidazopyrimidines; a new class of GABA brain receptor ligands
US5792766A (en) 1996-03-13 1998-08-11 Neurogen Corporation Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
KR20000048847A (ko) 1996-10-01 2000-07-25 스즈키 다다시 미토콘드리아 막 안정화제
WO1999058117A1 (fr) * 1998-05-13 1999-11-18 Sanofi-Synthelabo Utilisation de composes reduisant l'apoptose
FR2778564B1 (fr) * 1998-05-13 2001-07-13 Sanofi Sa Utilisation de composes reduisant l'apoptose
EP1607744A3 (en) * 1998-12-18 2009-09-30 Scios Inc. Treatment of diseases involving cyst formation with combinations comprising a PTBR agonist
EP1140107B1 (en) 1998-12-18 2006-07-19 Scios Inc. Agonists and antagonists of peripheral-type benzodiazepine receptors
AU2185000A (en) * 1998-12-18 2000-07-12 Scios Inc. Treatment of diseases involving cyst formation
WO2003030937A1 (fr) * 2001-10-05 2003-04-17 Ono Pharmaceutical Co., Ltd. Remedes contre des maladies liees au stress comprenant des antagonistes de recepteurs mithochondriaux de la benzodiazepine
US8053762B2 (en) * 2005-12-13 2011-11-08 Lg Chem, Ltd. Imidazoquinazoline derivative, process for preparing the same, and organic electronic device using the same
JP6129960B2 (ja) 2012-06-18 2017-05-17 ダート・ニューロサイエンス・（ケイマン）・リミテッド 置換ピリジンアゾロピリミジン−５−（６ｈ）−オン化合物
JP6420400B2 (ja) * 2017-04-12 2018-11-07 ダート・ニューロサイエンス・（ケイマン）・リミテッド 置換ピリジンアゾロピリミジン−５−（６ｈ）−オン化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4129653A (en) * 1977-01-05 1978-12-12 Ortho Pharmaceutical Corporation Substituted pyrrolo [1,2-c] quinazolines and pharmaceutical compositions and methods employing them
US4110452A (en) * 1977-10-17 1978-08-29 E. R. Squibb & Sons, Inc. Pyrazolo (1,5-c) quinazoline derivatives and related compounds
DE3046366A1 (de) * 1980-12-09 1982-07-08 Bayer Ag, 5090 Leverkusen Tricyclische cytosinderivate zur verwendung in arzneimitteln und verfahren zu ihrer herstellung
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
DK155524C (da) * 1987-03-18 1989-09-11 Ferrosan As Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse

Also Published As

Publication number Publication date
ZA911726B (en) 1991-12-24
US5128338A (en) 1992-07-07
PT96982A (pt) 1991-10-31
OA09488A (fr) 1992-11-15
FR2659329A1 (fr) 1991-09-13
FR2659329B1 (fr) 1994-06-03
JPH04217682A (ja) 1992-08-07
DE69106746D1 (de) 1995-03-02
DK0446141T3 (da) 1995-05-15
CA2037812A1 (fr) 1991-09-10
AU633408B2 (en) 1993-01-28
EP0446141A1 (fr) 1991-09-11
ATE117303T1 (de) 1995-02-15
IE910770A1 (en) 1991-09-11
EP0446141B1 (fr) 1995-01-18
GR3015514T3 (en) 1995-06-30
AU7274591A (en) 1991-09-12
DE69106746T2 (de) 1995-08-31
NZ237363A (en) 1992-12-23
IE66181B1 (en) 1995-12-13
JPH07103122B2 (ja) 1995-11-08

Similar Documents

Publication Publication Date Title
ES2069841T3 (es) Nuevos derivados de imidazo-(1,2-c)-quinazolina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
DK0649418T3 (da) 7-(2-aminoethyl)benzothiazolon
ES2014482B3 (es) Nuevas 2-tiazolil imidazo/1,2-a/pirimidinas y sus sales, su procedimiento de preparacion, su aplicacion a titulo de medicamentos y las composiciones que las encierran.
ES2069719T3 (es) Nuevos derivados de tiofeno, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
NO171786C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater
PT96164A (pt) Processo de preparacao de uma composicao farmaceutica a base de derivados de fluoroquinolona
ATE13885T1 (de) Phenylpiperazinderivate von hetarylphenolen und hetarylanilinen, ihre herstellung und diese enthaltende therapeutische mittel.
SE8604349D0 (sv) Dikloranilinderivat
ES2063157T3 (es) Nuevos derivados del indol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ATE90086T1 (de) Phenothiazinderivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
SE8400629L (sv) Basiska oximetrar
ES2054460T3 (es) Unos derivados de la ((1-arilpirrolidin-2-il)-metil)-piperazina, su preparacion y su aplicacion en terapeutica.
ES2068011T3 (es) Nuevos derivados de benzoato de etanol-amina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 446141

Country of ref document: ES