DK0446141T3 - Imidazo(1,2-c)quinazolinderivater og fremgangsmåde til fremstilling deraf samt farmaceutiske midler indeholdende dem - Google Patents

Imidazo(1,2-c)quinazolinderivater og fremgangsmåde til fremstilling deraf samt farmaceutiske midler indeholdende dem

Info

Publication number
DK0446141T3
DK0446141T3 DK91400645.7T DK91400645T DK0446141T3 DK 0446141 T3 DK0446141 T3 DK 0446141T3 DK 91400645 T DK91400645 T DK 91400645T DK 0446141 T3 DK0446141 T3 DK 0446141T3
Authority
DK
Denmark
Prior art keywords
optionally substituted
amino
imidazo
hydrogen
preparation
Prior art date
Application number
DK91400645.7T
Other languages
English (en)
Inventor
Camille-Georges Wermuth
Jean-Jacques Bourguignon
De La Faverie Jean-Fran Renaud
Catherine Thollon
Alain Lombet
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of DK0446141T3 publication Critical patent/DK0446141T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, ***e
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK91400645.7T 1990-03-09 1991-03-08 Imidazo(1,2-c)quinazolinderivater og fremgangsmåde til fremstilling deraf samt farmaceutiske midler indeholdende dem DK0446141T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9003003A FR2659329B1 (fr) 1990-03-09 1990-03-09 Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant.

Publications (1)

Publication Number Publication Date
DK0446141T3 true DK0446141T3 (da) 1995-05-15

Family

ID=9394556

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91400645.7T DK0446141T3 (da) 1990-03-09 1991-03-08 Imidazo(1,2-c)quinazolinderivater og fremgangsmåde til fremstilling deraf samt farmaceutiske midler indeholdende dem

Country Status (16)

Country Link
US (1) US5128338A (da)
EP (1) EP0446141B1 (da)
JP (1) JPH07103122B2 (da)
AT (1) ATE117303T1 (da)
AU (1) AU633408B2 (da)
CA (1) CA2037812A1 (da)
DE (1) DE69106746T2 (da)
DK (1) DK0446141T3 (da)
ES (1) ES2069841T3 (da)
FR (1) FR2659329B1 (da)
GR (1) GR3015514T3 (da)
IE (1) IE66181B1 (da)
NZ (1) NZ237363A (da)
OA (1) OA09488A (da)
PT (1) PT96982A (da)
ZA (1) ZA911726B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK588489D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK588389D0 (da) * 1989-11-22 1989-11-22 Ferrosan As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5512677A (en) * 1991-08-13 1996-04-30 National Science Council 3-substituted methyl-2,3-dihydroimidazo 1,2-c!quinazoline derivatives, the preparation and use thereof
US5158953A (en) * 1991-08-13 1992-10-27 National Science Council 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof
US5212310A (en) * 1991-12-19 1993-05-18 Neurogen Corporation Certain aryl fused imidazopyrimidines; a new class of GABA brain receptor ligands
US5792766A (en) 1996-03-13 1998-08-11 Neurogen Corporation Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
KR20000048847A (ko) 1996-10-01 2000-07-25 스즈키 다다시 미토콘드리아 막 안정화제
WO1999058117A1 (fr) * 1998-05-13 1999-11-18 Sanofi-Synthelabo Utilisation de composes reduisant l'apoptose
FR2778564B1 (fr) * 1998-05-13 2001-07-13 Sanofi Sa Utilisation de composes reduisant l'apoptose
AU2185100A (en) 1998-12-18 2000-07-12 Scios Inc. Agonists and antagonists of peripheral-type benzodiazepine receptors
EP1607744A3 (en) * 1998-12-18 2009-09-30 Scios Inc. Treatment of diseases involving cyst formation with combinations comprising a PTBR agonist
US6380183B1 (en) 1998-12-18 2002-04-30 Scios, Inc. Treatment of diseases involving cyst formation
EP1438973A4 (en) * 2001-10-05 2005-07-13 Ono Pharmaceutical Co MEANS FOR THE TREATMENT OF STRESS-RELATED DISEASES WITH MITOCHONDRIENE BENZODIAZEPINE RECEPTOR ANTAGONISTS
US8053762B2 (en) * 2005-12-13 2011-11-08 Lg Chem, Ltd. Imidazoquinazoline derivative, process for preparing the same, and organic electronic device using the same
BR112014031731B1 (pt) * 2012-06-18 2022-12-06 Dart Neuroscience (Cayman) Ltd Composto ou sal farmaceuticamente aceitável do mesmo, composição farmacêutica e respectivos usos
JP6420400B2 (ja) * 2017-04-12 2018-11-07 ダート・ニューロサイエンス・(ケイマン)・リミテッド 置換ピリジンアゾロピリミジン−5−(6h)−オン化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4129653A (en) * 1977-01-05 1978-12-12 Ortho Pharmaceutical Corporation Substituted pyrrolo [1,2-c] quinazolines and pharmaceutical compositions and methods employing them
US4110452A (en) * 1977-10-17 1978-08-29 E. R. Squibb & Sons, Inc. Pyrazolo (1,5-c) quinazoline derivatives and related compounds
DE3046366A1 (de) * 1980-12-09 1982-07-08 Bayer Ag, 5090 Leverkusen Tricyclische cytosinderivate zur verwendung in arzneimitteln und verfahren zu ihrer herstellung
US4713383A (en) * 1984-10-01 1987-12-15 Ciba-Geigy Corporation Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses
DK155524C (da) * 1987-03-18 1989-09-11 Ferrosan As Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse

Also Published As

Publication number Publication date
PT96982A (pt) 1991-10-31
ATE117303T1 (de) 1995-02-15
EP0446141A1 (fr) 1991-09-11
FR2659329B1 (fr) 1994-06-03
JPH04217682A (ja) 1992-08-07
ES2069841T3 (es) 1995-05-16
EP0446141B1 (fr) 1995-01-18
CA2037812A1 (fr) 1991-09-10
ZA911726B (en) 1991-12-24
DE69106746D1 (de) 1995-03-02
AU633408B2 (en) 1993-01-28
GR3015514T3 (en) 1995-06-30
IE910770A1 (en) 1991-09-11
JPH07103122B2 (ja) 1995-11-08
FR2659329A1 (fr) 1991-09-13
IE66181B1 (en) 1995-12-13
US5128338A (en) 1992-07-07
NZ237363A (en) 1992-12-23
DE69106746T2 (de) 1995-08-31
AU7274591A (en) 1991-09-12
OA09488A (fr) 1992-11-15

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