ES2065957T3 - Metodo para preparar esteres de acido 3-fenilglicidico opticamente activos. - Google Patents
Metodo para preparar esteres de acido 3-fenilglicidico opticamente activos.Info
- Publication number
- ES2065957T3 ES2065957T3 ES89116104T ES89116104T ES2065957T3 ES 2065957 T3 ES2065957 T3 ES 2065957T3 ES 89116104 T ES89116104 T ES 89116104T ES 89116104 T ES89116104 T ES 89116104T ES 2065957 T3 ES2065957 T3 ES 2065957T3
- Authority
- ES
- Spain
- Prior art keywords
- optically active
- acid esters
- preparing optically
- phenylglicidic
- phenylglicidic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
SE PRESENTA UN METODO PARA PREPARAR UN COMPUESTO DE ACIDO 3 - FENIL GLICIDICO OPTICAMENTE ACTIVO QUE COMPRENDE PERMITIR QUE UNA ENZIMA QUE TENGA LA HABILIDAD DE HIDROLIZAR ESTEREOSELECTIVAMENTE UN ENLACE DE UN ESTER QUE ACTUE SOBRE UN ACIDO 3 - FENIL GLICIDICO QUE PUEDE ESTAR SUSTITUIDO O INSUSTITUIDO EN EL GRUPO FENIL Y DE ESTA FORMA HIDROLIZAR ESTEREOSELECTIVAMENTE UNO DE LOS ISOMEROS OPTICAMENTE ACTIVOS Y SEPARAR Y RECOGER EL ANTIPODO DE LA MEZCLA DE REACCION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22101688 | 1988-09-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2065957T3 true ES2065957T3 (es) | 1995-03-01 |
Family
ID=16760161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89116104T Expired - Lifetime ES2065957T3 (es) | 1988-09-02 | 1989-08-31 | Metodo para preparar esteres de acido 3-fenilglicidico opticamente activos. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0362556B1 (es) |
KR (1) | KR960004455B1 (es) |
CN (1) | CN1041785A (es) |
AT (1) | ATE113661T1 (es) |
AU (1) | AU619890B2 (es) |
DE (1) | DE68919184T2 (es) |
DK (1) | DK173105B1 (es) |
ES (1) | ES2065957T3 (es) |
FI (1) | FI95931C (es) |
HU (1) | HU203581B (es) |
IE (1) | IE65881B1 (es) |
IL (1) | IL91453A0 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5274300A (en) | 1988-10-26 | 1993-12-28 | Sepracor, Inc. | Enzymatic hydrolysis of glycidate esters in the presence of bisulfite anion |
US6521445B1 (en) * | 1988-10-26 | 2003-02-18 | Sepracor, Inc. | Process for preparing optically active glycidate esters |
DE3927370A1 (de) * | 1989-08-19 | 1991-02-21 | Bayer Ag | Verfahren zur herstellung von clausenamid und neoclausenamid und deren derivate |
US5244803A (en) * | 1989-09-13 | 1993-09-14 | Tanabe Seiyaku Co., Ltd. | Process for preparing optically active 3-phenylglycidic acid esters |
ATE139563T1 (de) * | 1990-03-13 | 1996-07-15 | Tanabe Seiyaku Co | Esterase von serratia und verfahren zur herstellung |
JPH0779706B2 (ja) * | 1990-03-22 | 1995-08-30 | 田辺製薬株式会社 | 2―クロロ―3―ヒドロキシ―3―フエニルプロピオン酸エステル類の製法 |
IT1249777B (it) * | 1990-05-17 | 1995-03-18 | Zambon Spa | Processo per la preparazione di intermedi per la sintesi del diltiazem |
FR2672600B1 (fr) * | 1991-02-08 | 1994-10-14 | Synthelabo | Procede de preparation du (-)-(2r,3s)-2,3-epoxy-3-(4-methoxyphenyl) propionate de methyle. |
FI93833C (fi) * | 1992-05-14 | 1995-06-12 | Orion Yhtymae Oy | Menetelmä propionihappojohdosten valmistamiseksi |
MX9302853A (es) * | 1992-05-15 | 1993-11-01 | Syntex Pharma Int | Proceso enzimatico para producir acido (s)-6-metoxi-alfa-metil-2-naftalenacetico. |
US6020174A (en) * | 1992-07-27 | 2000-02-01 | The Board Of Governors For Higher Education | Chemoenzymatic synthesis of the taxol C-13 side chain N-benzolyl- (2R,3S)-Phenylisoserine |
NL9202208A (nl) * | 1992-12-18 | 1994-07-18 | Dsm Nv | Werkwijze voor de enzymatische bereiding van optisch aktieve glycidezure esters. |
CN1160421A (zh) * | 1994-10-12 | 1997-09-24 | 纳幕尔杜邦公司 | 制备手性α叔羧酸酯的酶促方法 |
US5529929A (en) * | 1995-06-07 | 1996-06-25 | Seprachem, Inc. | Optical resolution of alkyl 1,4-benzodioxan-2-carboxylates using esterase from serratia marcescens |
US5658796A (en) * | 1995-06-07 | 1997-08-19 | Seprachem, Inc. | Optical resolution of alkyl chroman-2-carboxylates |
IL121525A0 (en) * | 1996-08-26 | 1998-02-08 | Tanabe Seiyaku Co | Process for preparing optically active benzothiazepine compound and intermediate therefor |
IL123352A0 (en) * | 1997-02-27 | 1998-09-24 | Tanabe Seiyaku Co | Process for preparing an optically active trans-3-substituted glycidic acid ester |
IL133095A0 (en) * | 1997-06-11 | 2001-03-19 | Tanabe Seiyaku Co | Process for preparing optically active phenyloxirane compounds |
US7169944B2 (en) * | 2002-09-25 | 2007-01-30 | Tosoh Corporation | Optically active epoxy compounds and processes for their production |
KR100846676B1 (ko) * | 2006-04-27 | 2008-07-16 | 엔자이텍 주식회사 | 효소적 방법에 의한 광학활성 2-할로-2-(엔-치환된페닐)아세트산 에스테르와 2-할로-2-(엔-치환된페닐)아세트산의 제조 방법 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4585768A (en) * | 1984-04-10 | 1986-04-29 | Tanabe Seiyaku Co., Ltd. | 1,5-benzothiazepine derivatives and processes for preparing the same |
DE3532026A1 (de) * | 1985-09-09 | 1987-03-19 | Hoechst Ag | Verfahren zur herstellung optisch aktiver (alpha)-phenoxypropionsaeure und deren derivate |
IT1189069B (it) * | 1986-03-14 | 1988-01-28 | Donegani Guido Ist | Processo per la preparazione biotecnologica della l(-)-carnitina cloruro |
DE3752086T2 (de) * | 1986-04-16 | 1998-02-26 | Sumitomo Chemical Co | Verfahren zur Herstellung von optisch-aktiven Cyclopropancarbonsäure |
-
1989
- 1989-08-28 FI FI894022A patent/FI95931C/fi not_active IP Right Cessation
- 1989-08-28 IL IL91453A patent/IL91453A0/xx unknown
- 1989-08-31 DE DE68919184T patent/DE68919184T2/de not_active Expired - Fee Related
- 1989-08-31 AT AT89116104T patent/ATE113661T1/de not_active IP Right Cessation
- 1989-08-31 EP EP89116104A patent/EP0362556B1/en not_active Expired - Lifetime
- 1989-08-31 ES ES89116104T patent/ES2065957T3/es not_active Expired - Lifetime
- 1989-08-31 AU AU40977/89A patent/AU619890B2/en not_active Ceased
- 1989-09-01 IE IE281789A patent/IE65881B1/en not_active IP Right Cessation
- 1989-09-01 KR KR1019890012612A patent/KR960004455B1/ko not_active IP Right Cessation
- 1989-09-01 HU HU894539A patent/HU203581B/hu not_active IP Right Cessation
- 1989-09-01 DK DK198904348A patent/DK173105B1/da not_active IP Right Cessation
- 1989-09-02 CN CN89107005A patent/CN1041785A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
AU619890B2 (en) | 1992-02-06 |
CN1041785A (zh) | 1990-05-02 |
DE68919184T2 (de) | 1995-04-13 |
AU4097789A (en) | 1990-03-08 |
DK434889D0 (da) | 1989-09-01 |
FI95931B (fi) | 1995-12-29 |
DE68919184D1 (de) | 1994-12-08 |
DK434889A (da) | 1990-03-03 |
KR960004455B1 (ko) | 1996-04-06 |
IE892817L (en) | 1990-03-02 |
FI894022A0 (fi) | 1989-08-28 |
ATE113661T1 (de) | 1994-11-15 |
HU203581B (en) | 1991-08-28 |
HUT52162A (en) | 1990-06-28 |
FI95931C (fi) | 1996-04-10 |
FI894022A (fi) | 1990-03-03 |
IE65881B1 (en) | 1995-11-29 |
KR900004711A (ko) | 1990-04-12 |
EP0362556A1 (en) | 1990-04-11 |
IL91453A0 (en) | 1990-04-29 |
EP0362556B1 (en) | 1994-11-02 |
DK173105B1 (da) | 2000-01-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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