ES2058931T3 - Un reactivo para la deteccion de actividad fibrinolitica. - Google Patents
Un reactivo para la deteccion de actividad fibrinolitica.Info
- Publication number
- ES2058931T3 ES2058931T3 ES90912800T ES90912800T ES2058931T3 ES 2058931 T3 ES2058931 T3 ES 2058931T3 ES 90912800 T ES90912800 T ES 90912800T ES 90912800 T ES90912800 T ES 90912800T ES 2058931 T3 ES2058931 T3 ES 2058931T3
- Authority
- ES
- Spain
- Prior art keywords
- antibody
- fibrinolytic
- detection
- enzyme
- reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000001514 detection method Methods 0.000 title abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 2
- 230000003480 fibrinolytic effect Effects 0.000 title abstract 2
- 101710196208 Fibrinolytic enzyme Proteins 0.000 abstract 4
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/972—Plasminogen activators
- G01N2333/9726—Tissue plasminogen activator
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
UN REACTIVO DE DIAGNOSTICO PARA LA DETECCION IN VIVO DE UNA LIBERACION AUMENTADA DE UNA ENZIMA FIBRINOLITICA O DE UNA ACTIVIDAD FIBRINOLITICA AUMENTADA EN EL CUERPO HUMANO O DE ANIMALES QUE CONTIENE UN REACTIVO DE ANTICUERPO A UNA ENZIMA FRIBINOLITICA O UN FRAGMENTO DEL ANTICUERPO, MARCADO CON UNA SUSTANCIA QUE PERMITE LA DETECCION IN VIVO DEL ENLACE DEL ANTICUERPO A LA ENZIMA FIBRINOLITICA. EN UNA PUESTA EN PRACTICA DE LA INVENCION, LA SEPARACION AUMENTADA DEL ANTICUERPO ES PROPORCIONADA MEDIANTE LA ADMINISTRACION SUBSIGUIENTE DE LA ENZIMA FIBRINOLITICA A LA QUE ES REACTIVO EL ANTICUERPO. LA ENZIMA FIBRINOLITICA ES PREFERENTEMENTE T-PA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK408289A DK408289D0 (da) | 1989-08-18 | 1989-08-18 | Diagnostisk reagens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2058931T3 true ES2058931T3 (es) | 1994-11-01 |
Family
ID=8129992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES90912800T Expired - Lifetime ES2058931T3 (es) | 1989-08-18 | 1990-08-16 | Un reactivo para la deteccion de actividad fibrinolitica. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5165912A (es) |
| EP (1) | EP0487594B1 (es) |
| JP (1) | JPH04507254A (es) |
| KR (1) | KR920703120A (es) |
| AT (1) | ATE92770T1 (es) |
| AU (1) | AU639940B2 (es) |
| CA (1) | CA2065147A1 (es) |
| CZ (1) | CZ280904B6 (es) |
| DD (1) | DD297064A5 (es) |
| DE (1) | DE69002769T2 (es) |
| DK (2) | DK408289D0 (es) |
| ES (1) | ES2058931T3 (es) |
| FI (1) | FI920669A0 (es) |
| IE (1) | IE65525B1 (es) |
| IL (1) | IL95407A (es) |
| NO (1) | NO920624L (es) |
| NZ (1) | NZ234937A (es) |
| WO (1) | WO1991002546A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7544500B2 (en) * | 1999-11-13 | 2009-06-09 | Talecris Biotherapeutics, Inc. | Process for the production of a reversibly inactive acidified plasmin composition |
| US6964764B2 (en) * | 1999-11-13 | 2005-11-15 | Talecris Biotherapeutics, Inc. | Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin |
| US6355243B1 (en) * | 1999-11-13 | 2002-03-12 | Bayer Corporation | Method of thrombolysis by local delivery of active plasmin |
| US20080167544A1 (en) * | 2006-12-01 | 2008-07-10 | Cold Spring Diagnostics, Inc. | Compositions And Methods For Locating An Internal Bleeding Site |
| MX2010013282A (es) * | 2008-06-04 | 2010-12-21 | Talecris Biotherapeutics Inc | Composicion, metodo y kit para la preparacion de plasmina. |
| PL2403865T3 (pl) | 2009-03-03 | 2016-01-29 | Grifols Therapeutics Inc | Sposoby wytwarzania plazminogenu |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0169232B1 (en) * | 1984-01-23 | 1990-04-25 | For Energiteknikk Institutt | Composition for technetium-99m labelling of proteinaceous material |
| US4659839A (en) * | 1984-10-10 | 1987-04-21 | Mallinckrodt, Inc. | Coupling agents for radiolabeled antibody fragments |
| CA1285223C (en) * | 1986-11-10 | 1991-06-25 | New England Deaconess Hospital | Detection of vascular disease |
-
1989
- 1989-08-18 DK DK408289A patent/DK408289D0/da not_active Application Discontinuation
-
1990
- 1990-08-16 DE DE90912800T patent/DE69002769T2/de not_active Expired - Fee Related
- 1990-08-16 WO PCT/DK1990/000210 patent/WO1991002546A1/en active IP Right Grant
- 1990-08-16 EP EP90912800A patent/EP0487594B1/en not_active Expired - Lifetime
- 1990-08-16 JP JP2512113A patent/JPH04507254A/ja active Pending
- 1990-08-16 NZ NZ234937A patent/NZ234937A/xx unknown
- 1990-08-16 CA CA002065147A patent/CA2065147A1/en not_active Abandoned
- 1990-08-16 AT AT90912800T patent/ATE92770T1/de not_active IP Right Cessation
- 1990-08-16 ES ES90912800T patent/ES2058931T3/es not_active Expired - Lifetime
- 1990-08-16 AU AU62859/90A patent/AU639940B2/en not_active Ceased
- 1990-08-16 DD DD90343498A patent/DD297064A5/de not_active IP Right Cessation
- 1990-08-16 KR KR1019920700340A patent/KR920703120A/ko not_active Application Discontinuation
- 1990-08-16 DK DK90912800.1T patent/DK0487594T3/da active
- 1990-08-17 IE IE297790A patent/IE65525B1/en not_active IP Right Cessation
- 1990-08-17 US US07/569,127 patent/US5165912A/en not_active Expired - Fee Related
- 1990-08-17 IL IL9540790A patent/IL95407A/en not_active IP Right Cessation
- 1990-08-17 CZ CS904047A patent/CZ280904B6/cs unknown
-
1992
- 1992-02-17 NO NO92920624A patent/NO920624L/no unknown
- 1992-02-17 FI FI920669A patent/FI920669A0/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE92770T1 (de) | 1993-08-15 |
| AU6285990A (en) | 1991-04-03 |
| CZ404790A3 (en) | 1996-01-17 |
| FI920669A0 (fi) | 1992-02-17 |
| CZ280904B6 (cs) | 1996-05-15 |
| NO920624D0 (no) | 1992-02-17 |
| KR920703120A (ko) | 1992-12-17 |
| IL95407A (en) | 1994-07-31 |
| JPH04507254A (ja) | 1992-12-17 |
| US5165912A (en) | 1992-11-24 |
| DK0487594T3 (da) | 1994-01-03 |
| CA2065147A1 (en) | 1991-02-19 |
| NO920624L (no) | 1992-02-17 |
| AU639940B2 (en) | 1993-08-12 |
| DE69002769D1 (de) | 1993-09-16 |
| DD297064A5 (de) | 1992-01-02 |
| DE69002769T2 (de) | 1993-12-02 |
| EP0487594B1 (en) | 1993-08-11 |
| EP0487594A1 (en) | 1992-06-03 |
| IL95407A0 (en) | 1991-06-30 |
| DK408289D0 (da) | 1989-08-18 |
| NZ234937A (en) | 1991-11-26 |
| WO1991002546A1 (en) | 1991-03-07 |
| IE65525B1 (en) | 1995-11-01 |
| IE902977A1 (en) | 1991-02-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2530769T3 (es) | Métodos para la activación de células T in vivo por células dendríticas pulsadas con antígeno | |
| NZ253294A (en) | Extraction of prothrombin from blood | |
| ES2065303T3 (es) | Procedimiento de diagnosis y vacuna especifica. | |
| ES2035847T3 (es) | Un procedimiento para la elaboracion de una preparacion farmaceutica. | |
| UA6035A1 (uk) | Засіб для визначення лейкоцітів в сечі | |
| ES2058931T3 (es) | Un reactivo para la deteccion de actividad fibrinolitica. | |
| DK180682A (da) | Fremgangsmaade til fremstilling af et fibrinolytisk aktivt kar-princip og herved vundet enzymatisk produkt | |
| DK369287A (da) | Immunotoksiner og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende dem | |
| ES2184901T3 (es) | Anticuerpos anti-idiotipicos del factor de crecimiento endotelial vascular y su utilizacion como medicamentos. | |
| ES2075835T3 (es) | Correccion con arn de doble cadena de una insuficiencia en la arnasa l. | |
| AR004093A1 (es) | El uso de una proteina derivada de una quimioquina de mamifero y un medicamento util para movilizar celulas tronco hematopoyeticas. | |
| ES2047017T3 (es) | Agente de separacion acuoso para la produccion de cuerpos moldeados de poliuretano. | |
| DE3585049D1 (de) | Monoklonale antikoerper. | |
| FI881122A0 (fi) | Menetelmä tyvikalvoproteiinien eristämiseksi ihmis- ja eläinkudoksista | |
| DK112290D0 (da) | Vaevsplasminogenaktivator-variant | |
| FI885025A0 (fi) | Koagulationshaemmande protein pp4-x, dess framstaellning och anvaendning. | |
| ZA897586B (en) | Antidote | |
| DE3865642D1 (de) | Pharmazeutische zubereitung zur cholelitholyse. | |
| ES550932A0 (es) | Procedimiento para la determinacion cinetica de la actividad del sistema de complemento de sangre de ser humano o de animal mamifero. | |
| AR240063A1 (es) | Procedimiento para la produccion del activador del plasminogeno del tejido humano mediante el cultivo de la cepa de celulas registrada como kym-sf ifo 50135. | |
| FR2205571A1 (en) | Viral disease diagnosis - with antigen from incubated erythrocytes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 487594 Country of ref document: ES |