ES2054115T3 - Fenilhidrazonas, su fabricacion y medicamentos y productos cosmeticos fabricados a partir de estas. - Google Patents

Fenilhidrazonas, su fabricacion y medicamentos y productos cosmeticos fabricados a partir de estas.

Info

Publication number
ES2054115T3
ES2054115T3 ES90101946T ES90101946T ES2054115T3 ES 2054115 T3 ES2054115 T3 ES 2054115T3 ES 90101946 T ES90101946 T ES 90101946T ES 90101946 T ES90101946 T ES 90101946T ES 2054115 T3 ES2054115 T3 ES 2054115T3
Authority
ES
Spain
Prior art keywords
manufacture
medicines
products made
cosmetic products
phenyl hydrazones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90101946T
Other languages
English (en)
Inventor
Bernd Dr Janssen
Hans-Heiner Dr Wuest
William V Murray
Michael P Wachter
Stanley Bell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2054115T3 publication Critical patent/ES2054115T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/86—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/63—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C255/65—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to nitrogen atoms
    • C07C255/66—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to nitrogen atoms having cyano groups and nitrogen atoms being part of hydrazine or hydrazone groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/10—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/46—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4021—Esters of aromatic acids (P-C aromatic linkage)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Quinoline Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

EL INVENTO SE REFIERE A UNA FENILHIDRAZONA DE FORMULA (I); DESCRIBE LA PRODUCCION DEL COMPUESTO DE FORMULA (I) Y TRATA DE LA APLICACION DEL COMPUESTOS DE FORMULA (I) PARA EL TRATAMIENTO DE ENFERMEDADES Y COMO COSMETICO. TENIENDO R1 A R6 M Y N EL SIGNIFICADO DESCRITO EN LA PATENTE.
ES90101946T 1989-02-10 1990-02-01 Fenilhidrazonas, su fabricacion y medicamentos y productos cosmeticos fabricados a partir de estas. Expired - Lifetime ES2054115T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3903990A DE3903990A1 (de) 1989-02-10 1989-02-10 Phenylhydrazone, ihre herstellung und daraus hergestellte arzneimittel und kosmetika

Publications (1)

Publication Number Publication Date
ES2054115T3 true ES2054115T3 (es) 1994-08-01

Family

ID=6373811

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90101946T Expired - Lifetime ES2054115T3 (es) 1989-02-10 1990-02-01 Fenilhidrazonas, su fabricacion y medicamentos y productos cosmeticos fabricados a partir de estas.

Country Status (19)

Country Link
US (1) US5072042A (es)
EP (1) EP0382076B1 (es)
JP (1) JP2859350B2 (es)
KR (1) KR0168046B1 (es)
AT (1) ATE84783T1 (es)
AU (1) AU617036B2 (es)
CA (1) CA2009690C (es)
CZ (1) CZ283779B6 (es)
DE (2) DE3903990A1 (es)
DK (1) DK0382076T3 (es)
ES (1) ES2054115T3 (es)
FI (1) FI119638B (es)
GR (1) GR3006834T3 (es)
HU (1) HU205341B (es)
IL (1) IL93165A (es)
NO (1) NO172044C (es)
PL (1) PL164430B1 (es)
RU (1) RU1826967C (es)
ZA (1) ZA90962B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2039161B1 (es) * 1992-01-13 1994-04-01 Inst Investigacion Desarrollo Procedimiento de obtencion de nuevas hidrazonas con actividad antiproliferativa.
RU2137750C1 (ru) * 1998-05-19 1999-09-20 Институт органического синтеза Уральского отделения РАН Замещенные ди(формиларил)полиэфиры, или их координационные соединения, или их фармацевтически приемлемые аддитивные соли, способ их получения и фармацевтическая композиция на их основе
WO2001064646A2 (en) * 2000-03-01 2001-09-07 Tularik Inc. Hydrazones and analogs as cholesterol lowering agents
US7122571B2 (en) 2001-12-10 2006-10-17 Temple University - Of The Commonwealth System Of Higher Education Substituted hydrazones as inhibitors of cyclooxygenase-2
WO2004078174A1 (en) * 2003-02-28 2004-09-16 Morgan Lee R Resonance modulator for diagnosis and therapy
WO2004087641A1 (ja) * 2003-03-31 2004-10-14 Daiichi Pharmaceutical Co., Ltd. ヒドラゾン誘導体
EP1541549A1 (en) 2003-12-12 2005-06-15 Exonhit Therapeutics S.A. Tricyclic hydroxamate and benzaminde derivatives, compositions and methods
EP1951215A4 (en) * 2005-11-03 2009-07-29 Redpoint Bio Corp HYDRAZONE DERIVATIVES AND ITS USES
RU2009131697A (ru) * 2007-02-02 2011-03-10 Рэдпойнт Био Корпорэйшн (Us) Применение ингибитора trpm5 для регулирования секреции инсулина и гпп-1
JPWO2022168962A1 (es) * 2021-02-04 2022-08-11

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2350718A (en) * 1938-12-24 1944-06-06 Bretschneider Hermann Process of preparing alpha, beta-dialkyl-alpha, beta-diaryl-ethanes
DE1668035A1 (de) * 1967-08-10 1971-11-18 Hoechst Ag Substituierte p-Hydroxyphenylhydrazone und Verfahren zu ihrer Herstellung
US3829492A (en) * 1972-02-04 1974-08-13 Rohm & Haas Fungicidal salicylaldehyde hydrazones and azines
CH570389A5 (es) * 1972-06-16 1975-12-15 Ciba Geigy Ag
US3809675A (en) * 1972-11-08 1974-05-07 Bell Telephone Labor Inc Phenylhydrazone antioxidants for polyolefins
US4326055A (en) * 1977-12-22 1982-04-20 Hoffmann-La Roche Inc. Stilbene derivatives
US4265784A (en) * 1979-04-03 1981-05-05 General Electric Company Azine liquid crystal compounds for use in light-control devices
US4588750A (en) * 1982-07-02 1986-05-13 Hoffmann-La Roche Inc. Therapeutic compositions for reducing sebum secretion
LU85558A1 (fr) * 1984-09-28 1986-04-03 Oreal Nouveaux derives naphtaleniques a action retinoique,leurs procedes de preparation et compositions medicamenteuse et cosmetique les contenant
US4732904A (en) * 1984-12-24 1988-03-22 Morgan Lee R Antiestrogenic hydrazones

Also Published As

Publication number Publication date
HU205341B (en) 1992-04-28
HU900753D0 (en) 1990-04-28
IL93165A0 (en) 1990-11-05
DE59000769D1 (de) 1993-03-04
ZA90962B (en) 1991-10-30
US5072042A (en) 1991-12-10
CZ283779B6 (cs) 1998-06-17
DK0382076T3 (da) 1993-03-22
EP0382076A1 (de) 1990-08-16
GR3006834T3 (es) 1993-06-30
CA2009690C (en) 2002-04-16
PL164430B1 (pl) 1994-07-29
DE3903990A1 (de) 1990-08-30
EP0382076B1 (de) 1993-01-20
AU4926390A (en) 1990-08-16
NO172044C (no) 1993-06-02
KR900011717A (ko) 1990-08-02
RU1826967C (ru) 1993-07-07
CA2009690A1 (en) 1990-08-10
NO900633L (no) 1990-08-13
KR0168046B1 (ko) 1999-03-20
NO172044B (no) 1993-02-22
NO900633D0 (no) 1990-02-09
FI119638B (fi) 2009-01-30
HUT53069A (en) 1990-09-28
AU617036B2 (en) 1991-11-14
PL283722A1 (en) 1991-02-25
ATE84783T1 (de) 1993-02-15
CS55990A3 (en) 1992-05-13
IL93165A (en) 1994-02-27
JPH02250856A (ja) 1990-10-08
FI900646A0 (fi) 1990-02-09
JP2859350B2 (ja) 1999-02-17

Similar Documents

Publication Publication Date Title
MX9203496A (es) Derivados de difenilheteroalquilos, la preparacion de los mismos y drogas y cosmeticos preparados a partir de los mismos.
DE69630479D1 (de) Arzneimittel zur Behandlung von entzündlichen Herzkrankheiten
PT763037E (pt) Derivados de pirrol ¬a|-anelizados e sua utilizacao farmaceutica
ATE35136T1 (de) Neue benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
ES2054115T3 (es) Fenilhidrazonas, su fabricacion y medicamentos y productos cosmeticos fabricados a partir de estas.
FI922459A (fi) Foerfarande foer framstaellning av substituerade diaminoftalimider och deras analoger
SE8701406L (sv) Aromatiska foreningar, deras framtellningsforfarande och deras anvendning inom human- och veterinermedicinen och inom kosmetiken
IT8009551A0 (it) E-5-(2-alogenovinil-)-2'deossicitidine, loro metodo di preparazione e loro impiego per il trattamentodi malattie da virus
DE59001281D1 (de) Oxidierte diphenylheteroalkane, ihre herstellung und verwendung.
ES2054650T3 (es) Fenilacetonitrilos basicamente substituidos, su obtencion y medicamentos que los contienen.
ES511097A0 (es) "procedimiento para la preparacion de derivados de oxindol".
ES2128313T3 (es) Naftalimidas n-substituidas, su obtencion y empleo.
BE857794A (fr) Vaccin contre la maladie de l'oedeme de porcelet
ES2062313T3 (es) 13-bromo- y 13,14-dibromo-ergolinas, a su preparacion y a su utilizacion en medicamentos.
ES508757A0 (es) "procedimiento para la preparacion de acidos antranilicos sustituidos con radicales basicos"
DE59005487D1 (de) Phenylhydrazone des beta-Jonons, ihre Herstellung und daraus hergestellte Arzneimittel und Kosmetika.
MX9102627A (es) Composicion farmaceutica de dobutamina para administracion transdermica.
KR930703003A (ko) 피부질환치료용 제약 조성물

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 382076

Country of ref document: ES