IT8009551A0 - E-5-(2-alogenovinil-)-2'deossicitidine, loro metodo di preparazione e loro impiego per il trattamentodi malattie da virus - Google Patents

E-5-(2-alogenovinil-)-2'deossicitidine, loro metodo di preparazione e loro impiego per il trattamentodi malattie da virus

Info

Publication number
IT8009551A0
IT8009551A0 IT8009551A IT955180A IT8009551A0 IT 8009551 A0 IT8009551 A0 IT 8009551A0 IT 8009551 A IT8009551 A IT 8009551A IT 955180 A IT955180 A IT 955180A IT 8009551 A0 IT8009551 A0 IT 8009551A0
Authority
IT
Italy
Prior art keywords
halogenovinil
deoxycytidines
preparation
treatment
virus diseases
Prior art date
Application number
IT8009551A
Other languages
English (en)
Other versions
IT1209758B (it
Inventor
Albert Stanley Jones
Richard Thomas Walker
Clercq Erik De
Gabriel Albert Verhelst
Original Assignee
Stichting Rega V Z W The Unive
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Rega V Z W The Unive filed Critical Stichting Rega V Z W The Unive
Publication of IT8009551A0 publication Critical patent/IT8009551A0/it
Application granted granted Critical
Publication of IT1209758B publication Critical patent/IT1209758B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IT8009551A 1979-10-03 1980-10-02 E-5-(2-alogenovinil-)-2'deossicitidine, loro metodo di preparazione e loro impiego per il trattamentodi malattie da virus IT1209758B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7934248A GB2060604B (en) 1979-10-03 1979-10-03 E15-(2-halogenovinyl)-2'-deoxycytidines

Publications (2)

Publication Number Publication Date
IT8009551A0 true IT8009551A0 (it) 1980-10-02
IT1209758B IT1209758B (it) 1989-08-30

Family

ID=10508255

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8009551A IT1209758B (it) 1979-10-03 1980-10-02 E-5-(2-alogenovinil-)-2'deossicitidine, loro metodo di preparazione e loro impiego per il trattamentodi malattie da virus

Country Status (11)

Country Link
US (1) US4382925A (it)
JP (1) JPS5695198A (it)
BE (1) BE885415A (it)
CA (1) CA1173438A (it)
CH (1) CH647245A5 (it)
DE (1) DE3036131A1 (it)
FR (1) FR2466472A1 (it)
GB (1) GB2060604B (it)
IT (1) IT1209758B (it)
NL (1) NL8005336A (it)
SE (1) SE445740B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ199764A (en) * 1981-03-20 1984-08-24 Beecham Group Plc 5-(2-halogenovinyl)-2'-deoxyuridine derivatives and pharmaceutical compositions
HU183567B (en) * 1981-09-07 1984-05-28 Mta Koezponti Kemiai Kutato In Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof
JPS5843993A (ja) * 1981-09-09 1983-03-14 Yamasa Shoyu Co Ltd １−β−Ｄ−アラビノフラノシル−（Ｅ）−５−（２−ハロゲノビニル）ウラシル−５′−りん酸およびその製造法
EP0080305A1 (en) * 1981-11-19 1983-06-01 Beecham Group Plc Antiviral 2'-deoxyuridines, their preparation and use
EP0082668A1 (en) * 1981-12-18 1983-06-29 Beecham Group Plc 5-(2-Halogenovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them and their use in treating viral infections
US4782142A (en) * 1982-01-05 1988-11-01 The Research Foundation Of State University Of New York Novel 5-substituted 2-pyrimidinone nucleosides and methods of use
FI832884A (fi) * 1982-08-17 1984-02-18 Sandoz Ag Desoxiuridinderivat, deras framstaellningsfoerfaranden och anvaendning som farmaceutiska medel
IE55921B1 (en) * 1982-09-17 1991-02-27 Glaxo Group Ltd 5-halovinyl-2'-deoxyuridine derivatives
US4666892A (en) * 1984-03-06 1987-05-19 Sloan-Kettering Memorial Cancer Center Method and composition for hepatitis treatment with pyrimidine nucleoside compounds
AU575918B2 (en) * 1984-03-06 1988-08-11 Sloan-Kettering Institute For Cancer Research Hepatitis treatment with pyrimidine nucleoside compounds
US4762823A (en) * 1985-10-16 1988-08-09 Sloan-Kettering Institute For Cancer Research Nucleosides of 5-monofluoromethyluracil and 5-difluoromethyluracil
SE8605503D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel medicinal use
US5215971A (en) * 1986-12-19 1993-06-01 Medivir Ab Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides
WO1990001324A1 (en) * 1988-08-10 1990-02-22 Stephen Leslie Sacks PRODUCTION OF RADIOIODINATED 1-β-D-ARABINOFURANOSYL)-5(E)-(2-IODOVINYL)URACIL, AND USES THEREOF, AND RELATED ANALOGUES INCORPORATING ALTERNATIVE HALOGEN RADIONUCLIDES, THE GENERAL RADIOHALOGENATION PRECURSORS, 1-(2,3,5-TRI-O-ACETYL-β-D-ARABINOFURANOSYL)-5(Z and E)-(2-TRIMETHYLSILYLVINYL)URACIL, PROCESSES FOR RADIOHA
CA2405502A1 (en) * 2000-03-29 2001-10-04 Georgetown University Method of treating hepatitis delta viral infection
AU2002360697B2 (en) * 2001-12-20 2009-04-23 Beth Israel Deaconess Medical Center Treatment of EBV and KHSV infection and associated abnormal cellular proliferation
JP2008174524A (ja) * 2007-01-22 2008-07-31 Nippon Shinyaku Co Ltd リボ核酸化合物の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3354160A (en) * 1965-07-22 1967-11-21 Hoffmann La Roche Tri-lower alkyl-silyl-5-fluoropyrimidines
US4000260A (en) * 1974-08-29 1976-12-28 Research Corporation Anti herpes simplex viral compounds and their synthesis
US4024143A (en) * 1976-03-11 1977-05-17 Pcr, Inc. Silylation of 5-fluoro-6-hydroxy or alkoxy pyrimidine
US4267171A (en) * 1979-07-02 1981-05-12 The Regents Of The University Of California C-5 Substituted cytosine nucleosides

Also Published As

Publication number Publication date
DE3036131C2 (it) 1989-07-06
SE8006669L (sv) 1981-04-04
FR2466472B1 (it) 1983-12-23
SE445740B (sv) 1986-07-14
BE885415A (nl) 1981-03-26
CA1173438A (en) 1984-08-28
IT1209758B (it) 1989-08-30
FR2466472A1 (fr) 1981-04-10
JPS5695198A (en) 1981-08-01
CH647245A5 (de) 1985-01-15
GB2060604B (en) 1983-11-23
US4382925A (en) 1983-05-10
NL8005336A (nl) 1981-04-07
DE3036131A1 (de) 1981-04-16
JPS637199B2 (it) 1988-02-15
GB2060604A (en) 1981-05-07

Similar Documents

Publication Publication Date Title
IT7927524A0 (it) Proteine purificate e procedimento per la loro preparazione.
FR2483912B1 (fr) Derives hydroxycarboxyles du compose ml-236b, leur procede de preparation et leur application therapeutique
IT8024369A0 (it) Preparazione contenente metilsolfonilmetano e procedimenti per l'impiego e la purificazione di essa.
IT8009551A0 (it) E-5-(2-alogenovinil-)-2'deossicitidine, loro metodo di preparazione e loro impiego per il trattamentodi malattie da virus
IT1166756B (it) 1,3-diaril-2-imino-imidazolidine e 2-imino-esaidro-pirimidine sostituite e procedimento per la loro preparazione
IT1131682B (it) 2-(3,4,5-trimetossifenil)-tiazoli 4,5-bisostituiti e procedimento per la loro preparazione
IT8148952A0 (it) Amminoglucosidi ammidinati procedimento per loro preparazione e loro impiego come medicamenti
RO81212A (ro) Procedeu pentru prepararea unor 2',6'-dialchil-n-(alcoximetil)2-cloracetanilide
IT1099056B (it) 1,4-di-idro-piridazine,procedimento per la loro preparazione e loro impiego come prodotti medicinali
IT1194158B (it) Carbacicline,procedimento per la loro preparazione e loro impiego come medicinali
IT8247807A0 (it) 2,1,3-benzotiadiazoli e 2,1,3,-benzossadiazoli, loro preparazione e loro applicazione come medicamenti
IT1165040B (it) Alcossialchilidenidrazinopiridazione e procedimento per la loro preparazione
IT1170862B (it) Mercaptoacil-carnitine procedimento per la loro preparazione e loro uso terapeutico
IT8019070A0 (it) Oligopeptidi trifluorometilati, loro procedimento di preparazione eloro applicazione terapeutica
IT1167746B (it) Nitroimidazoli ad attivita' tricomonacida, procedimento per la loro preparazione e relative composizioni farmaceutiche
IT1206985B (it) Amminoalchilguanidine sostituite eprocedimento per la loro preparazione
IT1074511B (it) Procedimento per la preparazione di verbenone,mirtenale e pinocarveolo e loro impiego terapeutico
BE867776R (fr) Derives d'acides thiazolidinecarboxyliques, leur preparation et leur application
IT1145339B (it) Acidi-6ammino-spiro(penam-2,4'-piperidino)-3-carbossilici e loro procedimento di preparazione
IT7827394A0 (it) Procedimento per la preparazione di maltosio-fosforilasi o/e di bet-fosfoglucosio-mutasi e loro impiego.
IT1143906B (it) Tiocarnitine procedimento per la loro preparazione e loro uso terapeutico
IT1114703B (it) Composti benzimidazolici aventi attivita' antiinfiammatoria e procedimento per la loro preparazione
IT1130214B (it) 3, 4-epossipirrolidine 1-sostituite e procedimento per la loro preparazione
IT7950665A0 (it) Composti cicloalifatici dotati di proprieta' analgesiche e procedimento per la loro preparazione
IT8249656A0 (it) Preparato anti-infiammatorio nonsteroideo, per il trattamento delle affezioni artroreumatiche e metodo per la sua preparazione