ES2033426T3 - Procedimiento para la preparacion de composiciones farmaceuticas de liberacion controlada que contienen 3'-azido-3'-desoxitimidina. - Google Patents
Procedimiento para la preparacion de composiciones farmaceuticas de liberacion controlada que contienen 3'-azido-3'-desoxitimidina.Info
- Publication number
- ES2033426T3 ES2033426T3 ES198888302657T ES88302657T ES2033426T3 ES 2033426 T3 ES2033426 T3 ES 2033426T3 ES 198888302657 T ES198888302657 T ES 198888302657T ES 88302657 T ES88302657 T ES 88302657T ES 2033426 T3 ES2033426 T3 ES 2033426T3
- Authority
- ES
- Spain
- Prior art keywords
- controlled release
- deoxytimidine
- azido
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LA INVENCION SE REFIERE A FORMULACIONES FARMACEUTICAS QUE COMPRENDEN UNIDADES DISCRETAS DE ZIDOVIDINA PROPORCIONADAS CON UN RECUBRIMIENTO DE LIBERACION CONTROLADO EN EL QUE DICHAS UNIDADES ESTAS PREFERIBLEMENTE EN FORMA DE ESFEROIDES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878707421A GB8707421D0 (en) | 1987-03-27 | 1987-03-27 | Pharmaceutical formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2033426T3 true ES2033426T3 (es) | 1993-03-16 |
Family
ID=10614823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198888302657T Expired - Lifetime ES2033426T3 (es) | 1987-03-27 | 1988-03-25 | Procedimiento para la preparacion de composiciones farmaceuticas de liberacion controlada que contienen 3'-azido-3'-desoxitimidina. |
Country Status (17)
Country | Link |
---|---|
US (1) | US4917900A (es) |
EP (1) | EP0284407B1 (es) |
JP (1) | JP2719344B2 (es) |
KR (1) | KR960013434B1 (es) |
AT (1) | ATE63818T1 (es) |
AU (1) | AU607474B2 (es) |
CA (1) | CA1308026C (es) |
DE (1) | DE3862974D1 (es) |
DK (1) | DK175348B1 (es) |
ES (1) | ES2033426T3 (es) |
GB (1) | GB8707421D0 (es) |
GR (1) | GR3002030T3 (es) |
IE (1) | IE60605B1 (es) |
IL (1) | IL85870A (es) |
NZ (1) | NZ224026A (es) |
PT (1) | PT87081B (es) |
ZA (1) | ZA882168B (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5051361A (en) * | 1988-10-19 | 1991-09-24 | Sigma Chemical Company | AZT immunoassays, derivatives, conjugates and antibodies |
US4938966A (en) * | 1988-11-30 | 1990-07-03 | Riker Laboratories, Inc. | Controlled release flecainide acetate formulation |
GB8912420D0 (en) | 1989-05-31 | 1989-07-19 | Schram Cornelius J | Ultrasonic systems |
EP0452862B1 (en) * | 1990-04-18 | 1995-07-19 | Asahi Kasei Kogyo Kabushiki Kaisha | Spherical seed cores, spherical granules and process for production thereof |
US5102668A (en) * | 1990-10-05 | 1992-04-07 | Kingaform Technology, Inc. | Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH |
DE550714T1 (de) * | 1991-06-21 | 1995-06-14 | Acic Canada Inc | Antiviralverbindungen und Ihrer Verfahren zur Herstellung. |
KR100221695B1 (ko) * | 1991-08-12 | 1999-09-15 | 그린 마틴, 브라이언 쥐 테슬리 | 약학적 구상 제형 |
CA2141788C (en) * | 1992-08-04 | 2001-12-11 | James M. Dunn | Controlled release pharmaceutical formulations of 3'-azido-3'-deoxythymidine and methods of use |
FR2698560B1 (fr) * | 1992-11-30 | 1995-02-03 | Virbac Laboratoires | Principes actifs pulvérulents stabilisés, compositions les contenant, leur procédé d'obtention et leurs applications. |
US6245351B1 (en) | 1996-03-07 | 2001-06-12 | Takeda Chemical Industries, Ltd. | Controlled-release composition |
DE19945982A1 (de) | 1999-09-24 | 2001-03-29 | Knoll Ag | Geschwindigkeitsbestimmte Partikel |
AU2276801A (en) | 1999-12-20 | 2001-07-03 | Schering Corporation | Extended release oral dosage composition |
WO2001045668A2 (en) * | 1999-12-20 | 2001-06-28 | Schering Corporation | Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine |
KR20030011805A (ko) * | 2000-03-30 | 2003-02-11 | 브리스톨-마이어스스퀴브컴파니 | 스타부딘을 함유하는 서방성 비들렛 |
AU2003244110A1 (en) * | 2002-06-24 | 2004-01-06 | Asahi Denka Co., Ltd. | Flame retarder composition and flame retardant resin composition containing the composition |
US20050287177A1 (en) * | 2002-11-08 | 2005-12-29 | Glaxo Group Unlimited And Smithkline Beecham Corp. | Pharmaceutical compositions |
WO2005048978A2 (en) * | 2003-10-01 | 2005-06-02 | Lupin Limited | A controlled release pharmaceutical composition and a process for preparing the same |
GB0403247D0 (en) | 2004-02-13 | 2004-03-17 | Tillotts Pharma Ag | A pharmaceutical composition |
WO2005095950A1 (en) * | 2004-03-30 | 2005-10-13 | Pfizer Products Inc. | Method and device for evaluation of pharmaceutical compositions |
US20100062073A1 (en) * | 2006-11-29 | 2010-03-11 | Ronald Arthur Beyerinck | Pharmaceutical compositions comprising nanoparticles comprising enteric polymers casein |
US20100119612A1 (en) * | 2007-04-17 | 2010-05-13 | Bend Research, Inc | Nanoparticles comprising non-crystalline drug |
US8703204B2 (en) * | 2007-05-03 | 2014-04-22 | Bend Research, Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer |
WO2008135852A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Pharmaceutical compositions comprising nanoparticles and casein |
WO2008135828A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
WO2008149230A2 (en) | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate |
WO2008149192A2 (en) * | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
WO2009010842A2 (en) * | 2007-07-13 | 2009-01-22 | Pfizer Products Inc. | Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers |
US9233078B2 (en) * | 2007-12-06 | 2016-01-12 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer |
US9724362B2 (en) * | 2007-12-06 | 2017-08-08 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
US20140271893A1 (en) * | 2013-03-15 | 2014-09-18 | Mcneil-Ppc, Inc. | Coated phenylephrine particles and use thereof in pharmaceutical formulations |
CN106333957A (zh) * | 2016-08-19 | 2017-01-18 | 丁静 | 齐多夫定用于制备自身免疫性神经炎治疗药物的应用 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE145365C (es) * | ||||
BE785702A (fr) * | 1971-07-14 | 1972-10-16 | Roehm Gmbh | Produits de revetement de formes medicamenteuses et leur utilisation |
BE787973A (fr) * | 1971-09-04 | 1973-02-26 | Beecham Group Ltd | Comprimes pharmaceutiques a effet retard |
ES438635A1 (es) * | 1974-06-24 | 1977-02-16 | Shinetsu Chemical Co | Procedimiento para el revestimiento de moldes solidos de do-sificacion. |
ATE13486T1 (de) * | 1980-11-12 | 1985-06-15 | Ciba Geigy Ag | Schnellzerfallende arzneimittel-presslinge. |
EP0052075A1 (de) * | 1980-11-12 | 1982-05-19 | Ciba-Geigy Ag | Körnige Arzneimittel-Retardform |
DE3045135A1 (de) * | 1980-11-29 | 1982-06-09 | Sandoz-Patent-GmbH, 7850 Lörrach | Pharmazeutische kompositionen enthaltende bioabbaubare polymere |
DE3126703A1 (de) * | 1981-07-07 | 1983-01-27 | Dr. Karl Thomae Gmbh, 7950 Biberach | Bromhexin-retardform und verfahren zu ihrer herstellung |
ZA825384B (en) * | 1981-07-31 | 1983-05-25 | Tillott J B Ltd | Orally administrable pharmaceutical compositions |
IT1168014B (it) * | 1981-08-05 | 1987-05-20 | Erba Farmitalia | Forme farmaceutiche a cessione protratta |
DK150008C (da) * | 1981-11-20 | 1987-05-25 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat |
JPS59193831A (ja) * | 1983-04-18 | 1984-11-02 | Sankyo Co Ltd | 腸溶性製剤の製造法 |
JPS59227817A (ja) * | 1983-06-07 | 1984-12-21 | Toyo Jozo Co Ltd | 持続性経口用ブレデニン製剤 |
JPH075457B2 (ja) * | 1983-08-16 | 1995-01-25 | ザ ウエルカム フアウンデ−シヨン リミテツド | 調節された方法による有効成分の放出を可能にする医薬組成物 |
CH658188A5 (de) * | 1984-03-23 | 1986-10-31 | Ciba Geigy Ag | Lagerstabile schnellzerfallende pharmazeutische presslinge. |
DK164392C (da) * | 1985-03-16 | 1992-11-09 | Wellcome Found | Anvendelse af 3'-azido-3'-desoxythymidin til fremstilling af et laegemiddel til behandling af eller profylakse for en human retrovirusinfektion |
US4724232A (en) * | 1985-03-16 | 1988-02-09 | Burroughs Wellcome Co. | Treatment of human viral infections |
EP0199451B1 (en) * | 1985-03-16 | 1996-03-06 | The Wellcome Foundation Limited | Therapeutic nucleosides |
GB8506869D0 (en) * | 1985-03-16 | 1985-04-17 | Wellcome Found | Antiviral compound |
GB8519310D0 (en) * | 1985-07-31 | 1985-09-04 | Zyma Sa | Granular active substances |
IT1227336B (it) * | 1987-09-11 | 1991-04-08 | Squibb & Sons Inc | Composizione farmaceutica contenente un carico elevato di medicamento e procedimento per la sua preparazione |
-
1987
- 1987-03-27 GB GB878707421A patent/GB8707421D0/en active Pending
-
1988
- 1988-03-25 US US07/173,261 patent/US4917900A/en not_active Expired - Lifetime
- 1988-03-25 AT AT88302657T patent/ATE63818T1/de not_active IP Right Cessation
- 1988-03-25 IE IE89988A patent/IE60605B1/en not_active IP Right Cessation
- 1988-03-25 ZA ZA882168A patent/ZA882168B/xx unknown
- 1988-03-25 NZ NZ224026A patent/NZ224026A/xx unknown
- 1988-03-25 IL IL85870A patent/IL85870A/xx not_active IP Right Cessation
- 1988-03-25 ES ES198888302657T patent/ES2033426T3/es not_active Expired - Lifetime
- 1988-03-25 CA CA000562420A patent/CA1308026C/en not_active Expired - Lifetime
- 1988-03-25 JP JP63071708A patent/JP2719344B2/ja not_active Expired - Lifetime
- 1988-03-25 EP EP88302657A patent/EP0284407B1/en not_active Expired - Lifetime
- 1988-03-25 AU AU13756/88A patent/AU607474B2/en not_active Expired
- 1988-03-25 DE DE8888302657T patent/DE3862974D1/de not_active Expired - Lifetime
- 1988-03-25 PT PT87081A patent/PT87081B/pt not_active IP Right Cessation
- 1988-03-25 DK DK198801643A patent/DK175348B1/da not_active IP Right Cessation
- 1988-03-25 KR KR1019880003222A patent/KR960013434B1/ko not_active IP Right Cessation
-
1991
- 1991-05-30 GR GR91400615T patent/GR3002030T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK175348B1 (da) | 2004-09-06 |
KR880010759A (ko) | 1988-10-24 |
IE880899L (en) | 1988-09-27 |
EP0284407A2 (en) | 1988-09-28 |
AU1375688A (en) | 1988-09-29 |
EP0284407B1 (en) | 1991-05-29 |
DK164388D0 (da) | 1988-03-25 |
PT87081A (pt) | 1988-04-01 |
JP2719344B2 (ja) | 1998-02-25 |
CA1308026C (en) | 1992-09-29 |
PT87081B (pt) | 1992-07-31 |
ZA882168B (en) | 1989-11-29 |
KR960013434B1 (ko) | 1996-10-05 |
IE60605B1 (en) | 1994-07-27 |
IL85870A (en) | 1992-02-16 |
ATE63818T1 (de) | 1991-06-15 |
NZ224026A (en) | 1991-03-26 |
JPS63255230A (ja) | 1988-10-21 |
AU607474B2 (en) | 1991-03-07 |
EP0284407A3 (en) | 1988-12-14 |
US4917900A (en) | 1990-04-17 |
GR3002030T3 (en) | 1992-12-30 |
DE3862974D1 (de) | 1991-07-04 |
DK164388A (da) | 1988-09-28 |
GB8707421D0 (en) | 1987-04-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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