ES2027013T3 - Un procedimiento para preparar una forma de dosificacion de liberacion controlada. - Google Patents
Un procedimiento para preparar una forma de dosificacion de liberacion controlada.Info
- Publication number
- ES2027013T3 ES2027013T3 ES198888310271T ES88310271T ES2027013T3 ES 2027013 T3 ES2027013 T3 ES 2027013T3 ES 198888310271 T ES198888310271 T ES 198888310271T ES 88310271 T ES88310271 T ES 88310271T ES 2027013 T3 ES2027013 T3 ES 2027013T3
- Authority
- ES
- Spain
- Prior art keywords
- dosage form
- controlled release
- release dosage
- medicinal product
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002552 dosage form Substances 0.000 title abstract 3
- 238000013270 controlled release Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 abstract 3
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
UNA FORMA DE DOSIFICACION DE LIBERACION CONTROLADA QUE CONSISTE ESENCIALMENTE EN UN NUCLEO QUE CONTIENE UN MEDICAMENTO, UN FORRO INTERIOR EN CAPAS COMPUESTO DE ETILCELULOSA Y UNA SUSTANCIA HIDROFOBICA, Y UN FORRO EXTERNO EN CAPAS QUE CONTIENE UN MEDICAMENTO SE DESCRIBE. DICHA FORMA DE DOSIFICACION MUESTRA UNA RAPIDA ELEVACION DE LA CONCETRACION EN SANGRE DEL MEDICAMENTO Y AL MISMO TIEMPO MANTIENE LOS ALTOS NIVELES EN LA CONCENTRACION SANGUINEA DURANTE UN PROLONGADO PERIODO DE TIEMPO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP28118987 | 1987-11-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2027013T3 true ES2027013T3 (es) | 1992-05-16 |
Family
ID=17635585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198888310271T Expired - Lifetime ES2027013T3 (es) | 1987-11-06 | 1988-11-01 | Un procedimiento para preparar una forma de dosificacion de liberacion controlada. |
Country Status (24)
Country | Link |
---|---|
US (1) | US4963365A (es) |
EP (1) | EP0315414B1 (es) |
KR (1) | KR940002655B1 (es) |
CN (1) | CN1035099C (es) |
AT (1) | ATE68343T1 (es) |
AU (1) | AU610275B2 (es) |
BG (1) | BG60638B1 (es) |
CA (1) | CA1331565C (es) |
DE (1) | DE3865631D1 (es) |
DK (1) | DK175249B1 (es) |
ES (1) | ES2027013T3 (es) |
FI (1) | FI96273C (es) |
FR (1) | FR2622799B1 (es) |
GR (1) | GR3002915T3 (es) |
HK (1) | HK44593A (es) |
HU (1) | HU201468B (es) |
IE (1) | IE60785B1 (es) |
IL (1) | IL88083A (es) |
NO (1) | NO176233C (es) |
PH (1) | PH25905A (es) |
PT (1) | PT88945B (es) |
RU (1) | RU1816213C (es) |
SG (1) | SG15493G (es) |
ZA (1) | ZA888147B (es) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5169642A (en) * | 1988-06-24 | 1992-12-08 | Abbott Laboratories | Sustained-release drug dosage units |
US5268182A (en) * | 1988-06-24 | 1993-12-07 | Abbott Laboratories | Sustained-release drug dosage units of terazosin |
ES2044246T3 (es) * | 1989-02-11 | 1994-01-01 | Bayer Ag | Medicamentos con liberacion controlada del producto activo. |
US5258186A (en) * | 1989-03-10 | 1993-11-02 | Yamanouchi Pharmaceutical Co., Ltd. | Drug release controlling coating material for long acting formulations |
WO1990011074A1 (en) * | 1989-03-22 | 1990-10-04 | Pang Peter K T | Parathyroid hypertensive factor |
US5886012A (en) * | 1989-03-22 | 1999-03-23 | Peter K. T. Pang | Method of treatment for disease associated with excessive PHF using combination therapy involving exogenous calcium and calcium channel blockers |
US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
US5122384A (en) * | 1989-05-05 | 1992-06-16 | Kv Pharmaceutical Company | Oral once-per-day organic nitrate formulation which does not induce tolerance |
JP2558396B2 (ja) * | 1990-06-28 | 1996-11-27 | 田辺製薬株式会社 | 放出制御型製剤 |
DK0585355T3 (da) * | 1991-05-20 | 1995-06-06 | Tanabe Seiyaku Co | Flerlagspræparat med reguleret frigivelse |
ZA923474B (en) * | 1991-05-20 | 1993-01-27 | Marion Merrell Dow Inc | Diltiazem formulation |
US5286497A (en) * | 1991-05-20 | 1994-02-15 | Carderm Capital L.P. | Diltiazem formulation |
US5252337A (en) * | 1991-06-25 | 1993-10-12 | Eurand America, Inc. | Controlled release calcium channel blocker microcapsules |
GB9117361D0 (en) * | 1991-08-12 | 1991-09-25 | Euro Celtique Sa | Oral dosage form |
KR100221695B1 (ko) * | 1991-08-12 | 1999-09-15 | 그린 마틴, 브라이언 쥐 테슬리 | 약학적 구상 제형 |
US5492700A (en) * | 1991-11-26 | 1996-02-20 | Warner-Lambert Company | Process and composition for the development of controlled release gemfibrozil dosage form |
DE69327745T2 (de) * | 1992-05-29 | 2000-09-21 | Nikken Chemicals Co., Ltd. | Tablette zur langsamen Freisetzung von Natriumvalproat |
DE4342091A1 (de) * | 1993-12-09 | 1995-06-14 | Asta Medica Ag | Erzeugnisse zur Anwendung von initial hohen Dosen von Cetrorelix und Herstellung einer Kombinationspackung zur Verwendung bei Therapie von Krankheiten |
US5447729A (en) * | 1994-04-07 | 1995-09-05 | Pharmavene, Inc. | Multilamellar drug delivery systems |
US5567441A (en) * | 1995-03-24 | 1996-10-22 | Andrx Pharmaceuticals Inc. | Diltiazem controlled release formulation |
US5830503A (en) * | 1996-06-21 | 1998-11-03 | Andrx Pharmaceuticals, Inc. | Enteric coated diltiazem once-a-day formulation |
TW477708B (en) * | 1996-09-13 | 2002-03-01 | Shionogi & Amp Co | Use of the thermal change to produce a substained release preparations and a process for their production |
US6524620B2 (en) | 1998-07-20 | 2003-02-25 | Andrx Pharmaceuticals, Inc. | Diltiazem controlled release formulation and method of manufacture |
KR100396171B1 (ko) * | 1998-08-10 | 2003-08-27 | 아사히 가세이 가부시키가이샤 | 염산 파수딜의 경구 서방성 제제 |
US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
US6635277B2 (en) | 2000-04-12 | 2003-10-21 | Wockhardt Limited | Composition for pulsatile delivery of diltiazem and process of manufacture |
US6946146B2 (en) | 2001-04-18 | 2005-09-20 | Nostrum Pharmaceuticals Inc. | Coating for a sustained release pharmaceutical composition |
US20040029959A1 (en) * | 2002-08-08 | 2004-02-12 | John Devane | Isosorbide mononitrate compositions and methods of their use |
US9107804B2 (en) | 2002-12-10 | 2015-08-18 | Nortec Development Associates, Inc. | Method of preparing biologically active formulations |
CA2529984C (en) | 2003-06-26 | 2012-09-25 | Isa Odidi | Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors |
CN1296046C (zh) * | 2003-12-23 | 2007-01-24 | 广州市医药工业研究所 | 盐酸地尔硫䓬控释胶囊剂及其制备方法 |
US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
WO2007092717A1 (en) * | 2006-02-07 | 2007-08-16 | Fmc Corporation | Latex or pseudolatex compositions coatings and coating processes |
EP2007360B1 (en) | 2006-04-03 | 2014-11-26 | Isa Odidi | Controlled release delivery device comprising an organosol coat |
US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
US8927010B2 (en) * | 2011-03-23 | 2015-01-06 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US9283214B2 (en) | 2011-03-23 | 2016-03-15 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US8916588B2 (en) * | 2011-03-23 | 2014-12-23 | Ironshore Pharmaceuticals & Development, Inc. | Methods for treatment of attention deficit hyperactivity disorder |
US9498447B2 (en) | 2011-03-23 | 2016-11-22 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US9603809B2 (en) | 2011-03-23 | 2017-03-28 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
US10292937B2 (en) * | 2011-03-23 | 2019-05-21 | Ironshore Pharmaceuticals & Development, Inc. | Methods of treatment of attention deficit hyperactivity disorder |
US10905652B2 (en) | 2011-03-23 | 2021-02-02 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US9119809B2 (en) | 2011-03-23 | 2015-09-01 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
US11241391B2 (en) | 2011-03-23 | 2022-02-08 | Ironshore Pharmaceuticals & Development, Inc. | Compositions for treatment of attention deficit hyperactivity disorder |
EP2529731A1 (en) * | 2011-06-01 | 2012-12-05 | Nitto Denko Corporation | Particulate preparation and method for producing the same |
FR2996418B1 (fr) * | 2012-10-09 | 2015-05-29 | Seppic Sa | Compositions alimentaires comprenant des capsules obtenues par coacervation ne mettant pas en œuvre de reticulant toxique |
WO2014078435A1 (en) | 2012-11-14 | 2014-05-22 | W. R. Grace & Co.-Conn. | Compositions containing a biologically active material and a non-ordered inorganic oxide |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1172087A (fr) * | 1956-01-25 | 1959-02-05 | Bellon Labor Sa Roger | Perfectionnements concernant l'enrobage de préparations à effet retardé et à effet soutenu |
US2921883A (en) * | 1957-05-03 | 1960-01-19 | Smith Kline French Lab | Novel coating material for medicaments |
US2928770A (en) * | 1958-11-28 | 1960-03-15 | Frank M Bardani | Sustained action pill |
US3492397A (en) * | 1967-04-07 | 1970-01-27 | Warner Lambert Pharmaceutical | Sustained release dosage in the pellet form and process thereof |
IT1153487B (it) * | 1982-04-15 | 1987-01-14 | Prophin Lab Spa | Prodotti farmaceutici in forma-ritardo e procedimento per ottenerli |
US4390406A (en) * | 1982-07-23 | 1983-06-28 | Allied Corporation | Replaceable outer junction double junction reference electrode |
JPS604120A (ja) * | 1983-06-22 | 1985-01-10 | Shionogi & Co Ltd | 作用持続型ピナシジル製剤 |
IE56999B1 (en) * | 1983-12-22 | 1992-03-11 | Elan Corp Plc | Pharmaceutical formulation |
SE457505B (sv) * | 1984-01-10 | 1989-01-09 | Lejus Medical Ab | Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning |
DE3403329A1 (de) * | 1984-02-01 | 1985-08-01 | Horst Dr. 4019 Monheim Zerbe | Pharmazeutisches produkt in form von pellets mit kontinuierlicher, verzoegerter wirkstoffabgabe |
IT1206166B (it) * | 1984-07-26 | 1989-04-14 | Sigma Tau Ind Farmaceuti | Dispositivo per rilasciare una sostanza in un fluido di dissoluzione con cinetica di ordine zero e procedimento per la sua preparazione |
US4851228A (en) * | 1984-06-20 | 1989-07-25 | Merck & Co., Inc. | Multiparticulate controlled porosity osmotic |
US4600645A (en) * | 1985-01-31 | 1986-07-15 | Warner-Lambert Company | Process for treating dosage forms |
JPS62103012A (ja) * | 1985-10-23 | 1987-05-13 | Eisai Co Ltd | 多重顆粒 |
US4842867A (en) * | 1986-05-09 | 1989-06-27 | Alza Corporation | Pulsed drug delivery of doxylamine |
US4795644A (en) * | 1987-08-03 | 1989-01-03 | Merck & Co., Inc. | Device for pH independent release of drugs through the Donnan-like influence of charged insoluble resins |
-
1988
- 1988-10-19 IL IL88083A patent/IL88083A/xx not_active IP Right Cessation
- 1988-10-26 IE IE324688A patent/IE60785B1/en not_active IP Right Cessation
- 1988-10-31 ZA ZA888147A patent/ZA888147B/xx unknown
- 1988-11-01 DE DE8888310271T patent/DE3865631D1/de not_active Expired - Lifetime
- 1988-11-01 ES ES198888310271T patent/ES2027013T3/es not_active Expired - Lifetime
- 1988-11-01 AT AT88310271T patent/ATE68343T1/de not_active IP Right Cessation
- 1988-11-01 EP EP88310271A patent/EP0315414B1/en not_active Expired - Lifetime
- 1988-11-03 CA CA000582132A patent/CA1331565C/en not_active Expired - Lifetime
- 1988-11-03 BG BG85941A patent/BG60638B1/bg unknown
- 1988-11-04 FR FR888814466A patent/FR2622799B1/fr not_active Expired - Lifetime
- 1988-11-04 HU HU885710A patent/HU201468B/hu unknown
- 1988-11-04 RU SU884356826A patent/RU1816213C/ru active
- 1988-11-04 DK DK198806180A patent/DK175249B1/da not_active IP Right Cessation
- 1988-11-04 NO NO884947A patent/NO176233C/no not_active IP Right Cessation
- 1988-11-04 FI FI885101A patent/FI96273C/fi not_active IP Right Cessation
- 1988-11-04 AU AU24727/88A patent/AU610275B2/en not_active Expired
- 1988-11-04 PT PT88945A patent/PT88945B/pt not_active IP Right Cessation
- 1988-11-04 US US07/267,085 patent/US4963365A/en not_active Expired - Lifetime
- 1988-11-04 PH PH3772A patent/PH25905A/en unknown
- 1988-11-05 CN CN88107687A patent/CN1035099C/zh not_active Expired - Lifetime
- 1988-11-05 KR KR1019880014528A patent/KR940002655B1/ko not_active IP Right Cessation
-
1991
- 1991-10-17 GR GR91401439T patent/GR3002915T3/el unknown
-
1993
- 1993-02-11 SG SG154/93A patent/SG15493G/en unknown
- 1993-05-06 HK HK445/93A patent/HK44593A/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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