DE69000881D1 - 2-propylvaleriansaeure enthaltende arzneizubereitung mit verzoegerter wirkstofffreigabe. - Google Patents

2-propylvaleriansaeure enthaltende arzneizubereitung mit verzoegerter wirkstofffreigabe.

Info

Publication number
DE69000881D1
DE69000881D1 DE9090400533T DE69000881T DE69000881D1 DE 69000881 D1 DE69000881 D1 DE 69000881D1 DE 9090400533 T DE9090400533 T DE 9090400533T DE 69000881 T DE69000881 T DE 69000881T DE 69000881 D1 DE69000881 D1 DE 69000881D1
Authority
DE
Germany
Prior art keywords
active substance
medicine preparation
delayed release
preparation containing
propylvaleric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE9090400533T
Other languages
English (en)
Other versions
DE69000881T2 (de
Inventor
Georges Daste
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Elf Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elf Sanofi SA filed Critical Elf Sanofi SA
Publication of DE69000881D1 publication Critical patent/DE69000881D1/de
Application granted granted Critical
Publication of DE69000881T2 publication Critical patent/DE69000881T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2813—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE9090400533T 1989-02-27 1990-02-26 2-propylvaleriansaeure enthaltende arzneizubereitung mit verzoegerter wirkstofffreigabe. Expired - Lifetime DE69000881T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8902493A FR2643556B1 (fr) 1989-02-27 1989-02-27 Composition pharmaceutique a liberation prolongee d'acide valproique

Publications (2)

Publication Number Publication Date
DE69000881D1 true DE69000881D1 (de) 1993-03-25
DE69000881T2 DE69000881T2 (de) 1993-08-12

Family

ID=9379141

Family Applications (1)

Application Number Title Priority Date Filing Date
DE9090400533T Expired - Lifetime DE69000881T2 (de) 1989-02-27 1990-02-26 2-propylvaleriansaeure enthaltende arzneizubereitung mit verzoegerter wirkstofffreigabe.

Country Status (7)

Country Link
US (1) US5019398A (de)
EP (1) EP0385846B1 (de)
AU (1) AU623225B2 (de)
CA (1) CA2010427A1 (de)
DE (1) DE69000881T2 (de)
FR (1) FR2643556B1 (de)
NZ (1) NZ232649A (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169642A (en) * 1988-06-24 1992-12-08 Abbott Laboratories Sustained-release drug dosage units
US5268182A (en) * 1988-06-24 1993-12-07 Abbott Laboratories Sustained-release drug dosage units of terazosin
US5356629A (en) * 1991-07-12 1994-10-18 United States Surgical Corporation Composition for effecting bone repair
PT571973E (pt) * 1992-05-29 2000-05-31 Nikken Chemicals Co Ltd Comprimidos de valproato de sodio de libertacao retardada
US6287598B1 (en) * 1993-05-28 2001-09-11 Alza Corporation Method for providing sustained antiepileptic therapy
US5609883A (en) * 1994-09-16 1997-03-11 Advanced Technology Pharmaceuticals Corporation Compressed tablet transitory lubricant system
NZ270438A (en) * 1995-02-02 1996-03-26 Bernard Charles Sherman Solid (granular) mixture of valproic acid (di-n-propyl acetic acid) and its sodium salt; pharmaceutical compositions
CA2216934A1 (en) * 1995-04-03 1996-10-10 Abbott Laboratories Homogeneous mixtures of low temperature-melting drugs and additives for controlled release
JPH09323926A (ja) * 1996-03-15 1997-12-16 Nikken Chem Co Ltd バルプロ酸ナトリウムの徐放性錠剤
DE19840152A1 (de) * 1998-09-03 2000-03-09 Dresden Arzneimittel Calciumvalproat enthaltende pharmazeutische Zusammensetzungen mit retardierter Wirkstoff-Freisetzung, Verfahren zu deren Herstellung und deren Verwendung
PE20001302A1 (es) 1998-11-27 2000-11-30 Hoffmann La Roche Preparaciones de una combinacion farmaceutica que contiene carvedilol e hidroclorotiazida
US20020031549A1 (en) * 1998-12-18 2002-03-14 Yihong Qiu Controlled release formulation of divalproex sodium
US6419953B1 (en) 1998-12-18 2002-07-16 Abbott Laboratories Controlled release formulation of divalproex sodium
US20020025341A1 (en) * 1998-12-18 2002-02-28 Yihong Qiu Controlled release formulation of divalproex sodium
US6528090B2 (en) 1998-12-18 2003-03-04 Abbott Laboratories Controlled release formulation of divalproex sodium
US6511678B2 (en) 1998-12-18 2003-01-28 Abbott Laboratories Controlled release formulation of divalproex sodium
CZ20012201A3 (cs) * 1998-12-18 2001-09-12 Abbott Laboratories Přípravek s řízeným uvolňováním obsahující divalproex sodný
US6713086B2 (en) 1998-12-18 2004-03-30 Abbott Laboratories Controlled release formulation of divalproex sodium
US6150410A (en) * 1999-02-04 2000-11-21 Abbott Laboratories pH independent extended release pharmaceutical formulation
DK1146864T3 (da) * 1999-02-04 2009-05-11 Abbott Lab pH-uafhængig farmaceutisk formulering med forlænget frisætning
WO2002051402A1 (en) * 2000-12-22 2002-07-04 Abbott Laboratories Controlled release formulation of divalproex sodium
AU2003269741A1 (en) * 2002-05-15 2003-12-02 Sun Pharmaceutical Industries Limited Coated sustained release tablets of a hygroscopic compound for once-a-day therapy
ATE540129T1 (de) * 2002-11-22 2012-01-15 Univ Johns Hopkins Target zur therapie kognitiver behinderungen
WO2005079753A2 (en) * 2004-02-19 2005-09-01 Ranbaxy Laboratories Limited Extended release pharmaceutical compositions of divalproex sodium
WO2006010995A1 (en) * 2004-07-23 2006-02-02 Wockhardt Limited Controlled release compositions of divalproex sodium
WO2006064321A2 (en) * 2004-12-13 2006-06-22 Wockhardt Limited Controlled release compositions of divalproex sodium
US20070048379A1 (en) * 2005-08-29 2007-03-01 Mintong Guo Valproate tablet
HK1081802A2 (en) * 2005-09-09 2006-05-19 Jacky Lam Chi Sum Intelligent crossroad
US20070160667A1 (en) * 2006-01-11 2007-07-12 Nava Shterman Controlled release formulation of divalproex sodium
PT1815850E (pt) 2006-01-11 2009-01-06 Teva Pharma Formulação de libertação controlada de ácido divalpróico e seus derivados
US20080081069A1 (en) * 2006-09-28 2008-04-03 Lupin Limited Novel controlled release formulations of divalproex sodium
CN102807791B (zh) * 2007-11-09 2014-10-15 联合碳化化学品及塑料技术公司 制备非常低粘度的纤维素醚的方法和产品
CN102227217A (zh) * 2008-10-16 2011-10-26 约翰斯.霍普金斯大学 改善认知功能的方法和组合物
EA037187B1 (ru) * 2010-02-09 2021-02-17 Дзе Джонс Хопкинс Юниверсити Способ и композиция для лечения когнитивного расстройства
BR112013027685A2 (pt) 2011-05-02 2016-12-27 Abbott Healthcare Private Ltd composição oral líquida compreendendo divalproex sódico e processo de preparação do mesmo
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
WO2014144801A1 (en) 2013-03-15 2014-09-18 Agenebio Inc. Methods and compositions for improving cognitive function
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
US10925834B2 (en) 2015-05-22 2021-02-23 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam
CN111012753A (zh) * 2020-01-07 2020-04-17 仁和堂药业有限公司 一种提高丙戊酸钠片剂稳定性的方法
CN113304117B (zh) * 2021-04-30 2023-05-12 山东京卫制药有限公司 一种丙戊酸钠缓释片的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3063328D1 (en) * 1979-08-20 1983-07-07 Abbott Lab Mixed salt of valproic acid
US4301176A (en) * 1980-08-18 1981-11-17 Warner-Lambert Company Method of administering calcium valproate
CA1136351A (en) * 1980-10-10 1982-11-30 Vagn A. Hansen Stayless shirt collar
IL72381A (en) * 1983-07-20 1988-03-31 Sanofi Sa Pharmaceutical composition based on valproic acid
US4558070A (en) * 1983-10-26 1985-12-10 Abbott Laboratories Acid salts of valproic acid

Also Published As

Publication number Publication date
US5019398A (en) 1991-05-28
EP0385846A1 (de) 1990-09-05
FR2643556B1 (fr) 1993-03-05
NZ232649A (en) 1991-01-29
FR2643556A1 (fr) 1990-08-31
AU623225B2 (en) 1992-05-07
AU4999890A (en) 1990-08-30
EP0385846B1 (de) 1993-02-10
DE69000881T2 (de) 1993-08-12
CA2010427A1 (en) 1990-08-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-SYNTHELABO, PARIS, FR

8328 Change in the person/name/address of the agent

Free format text: TER MEER STEINMEISTER & PARTNER GBR PATENTANWAELTE, 81679 MUENCHEN

8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS, PARIS, FR