ES2005778A6 - Procedimiento para la obtencion de derivados de diisobutilxantina. - Google Patents
Procedimiento para la obtencion de derivados de diisobutilxantina.Info
- Publication number
- ES2005778A6 ES2005778A6 ES888800441A ES8800441A ES2005778A6 ES 2005778 A6 ES2005778 A6 ES 2005778A6 ES 888800441 A ES888800441 A ES 888800441A ES 8800441 A ES8800441 A ES 8800441A ES 2005778 A6 ES2005778 A6 ES 2005778A6
- Authority
- ES
- Spain
- Prior art keywords
- diisobutylxanthine
- bronchodilators
- useful
- preparation
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UN PROCEDIMIENTO PARA OBTENER 1,3-DIISOBUTIL-8-METILXANTINAS DE FORMULA (I):EN DONDE R1 ES UN GRUPO ETOXICARBONILO, 2-(DIETILAMINO)ETILO O 2,3-DIHIDROXIPROPILO, MEDIANTE REACCION DE LA 1,3-DIISOBUTIL-8-METILXANTINA (I, R1=H), O UNA SAL DE LA MISMA (I, R1=LI, NA, K, ETC.), CON UN COMPUESTO R1-X, EN DONDE R1 TIENE EL SIGNIFICADO ANTES INDICADO Y X ES UN GRUPO SALIENTE. LA REACCION SE REALIZA EN EL SENO DE UN DISOLVENTE POLAR, GENERALMENTE A LA TEMPERATURA DE REFLUJO DE DICHO DISOLVENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8703112A FR2611716A1 (fr) | 1987-03-06 | 1987-03-06 | Derives de diisobutylxanthine substituee en position 7 utiles comme bronchodilatateurs, procede pour leur preparation et composition pharmaceutique les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2005778A6 true ES2005778A6 (es) | 1989-03-16 |
Family
ID=9348701
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES888800441A Expired ES2005778A6 (es) | 1987-03-06 | 1988-02-17 | Procedimiento para la obtencion de derivados de diisobutilxantina. |
Country Status (2)
Country | Link |
---|---|
ES (1) | ES2005778A6 (es) |
FR (1) | FR2611716A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0407651A3 (en) * | 1989-07-10 | 1991-08-07 | J. Uriach & Cia. S.A. | Use of 1,3-diisobutyl-8-methylxanthine as a bronchodilator and antiallergy agent |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE636828A (es) * | ||||
CA1077932A (en) * | 1976-03-31 | 1980-05-20 | Berlex Laboratories, Inc. | Xanthine compounds and method of treating bronchospastic and allergic diseases |
US4031218A (en) * | 1976-04-28 | 1977-06-21 | Mallinckrodt, Inc. | 7-(2,3-Dihydroxypropyl-1,3-di-n-propylxanthine and a pharmaceutical composition containing same useful as a bronchial muscle relaxant |
DE3138397A1 (de) * | 1981-09-26 | 1983-04-07 | Hoechst Ag, 6230 Frankfurt | "arzneimittel, darin enthaltene vicinale dihydroxyalkylxanthine und herstellungsverfahren fuer diese xanthinverbindungen" |
-
1987
- 1987-03-06 FR FR8703112A patent/FR2611716A1/fr not_active Withdrawn
-
1988
- 1988-02-17 ES ES888800441A patent/ES2005778A6/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2611716A1 (fr) | 1988-09-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20000301 |