EP3946311A4 - ANESTHETICAL COMPOSITION AND METHOD OF ANESTHIZATION OF THE EYE - Google Patents

ANESTHETICAL COMPOSITION AND METHOD OF ANESTHIZATION OF THE EYE Download PDF

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Publication number
EP3946311A4
EP3946311A4 EP20776365.7A EP20776365A EP3946311A4 EP 3946311 A4 EP3946311 A4 EP 3946311A4 EP 20776365 A EP20776365 A EP 20776365A EP 3946311 A4 EP3946311 A4 EP 3946311A4
Authority
EP
European Patent Office
Prior art keywords
anesthetizing
eye
anesthetic composition
anesthetic
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20776365.7A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3946311A1 (en
Inventor
Martin Uram
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2019/024239 external-priority patent/WO2019191200A1/en
Application filed by Individual filed Critical Individual
Publication of EP3946311A1 publication Critical patent/EP3946311A1/en
Publication of EP3946311A4 publication Critical patent/EP3946311A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP20776365.7A 2019-03-26 2020-03-16 ANESTHETICAL COMPOSITION AND METHOD OF ANESTHIZATION OF THE EYE Pending EP3946311A4 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962824207P 2019-03-26 2019-03-26
PCT/US2019/024239 WO2019191200A1 (en) 2018-03-27 2019-03-27 Method and formulation for producing anesthesia of internal aspect of eye wall by topical application
US16/811,798 US11096922B2 (en) 2018-03-27 2020-03-06 Anesthetic composition and method of anesthetizing the eye
PCT/US2020/022915 WO2020197816A1 (en) 2019-03-26 2020-03-16 Anesthetic composition and method of anesthetizing the eye

Publications (2)

Publication Number Publication Date
EP3946311A1 EP3946311A1 (en) 2022-02-09
EP3946311A4 true EP3946311A4 (en) 2022-12-28

Family

ID=72609654

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20776365.7A Pending EP3946311A4 (en) 2019-03-26 2020-03-16 ANESTHETICAL COMPOSITION AND METHOD OF ANESTHIZATION OF THE EYE

Country Status (11)

Country Link
EP (1) EP3946311A4 (ko)
JP (1) JP2022527621A (ko)
KR (1) KR20210143254A (ko)
CN (1) CN114072139A (ko)
AU (1) AU2020245203A1 (ko)
BR (1) BR112021019039A2 (ko)
CA (1) CA3134531A1 (ko)
IL (1) IL286624A (ko)
MX (1) MX2021011589A (ko)
SG (1) SG11202110423UA (ko)
WO (1) WO2020197816A1 (ko)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021903A1 (en) * 1992-05-06 1993-11-11 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
CN101695488A (zh) * 2009-11-05 2010-04-21 蚌埠丰原涂山制药有限公司 复方阿替卡因注射用冻干制剂及其制备方法
WO2018220288A1 (fr) * 2017-05-29 2018-12-06 Tauzin Benedicte Vincente Composition injectable stérile contenant de l'acide hyaluronique réticule et de l'articaine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE547122T1 (de) * 2001-11-21 2012-03-15 Novartis Pharma Gmbh Zusammensetzung zur stabilisierung von hyaluronsäure
CN101721407B (zh) * 2009-11-23 2013-04-10 蚌埠丰原涂山制药有限公司 复方盐酸阿替卡因注射液及其制备方法
FR2968996B1 (fr) * 2010-12-17 2013-04-12 Anteis Sa Formulation aqueuse injectable sterile utilisee en ophtalmologie
FR3036035B1 (fr) * 2015-05-11 2018-10-05 Laboratoires Vivacy Compositions comprenant au moins un polyol et au moins un anesthesique
JP2018526423A (ja) * 2015-09-08 2018-09-13 ビューポイント セラピューティクス， インコーポレイテッド 眼科疾患を処置するための化合物および製剤

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021903A1 (en) * 1992-05-06 1993-11-11 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
CN101695488A (zh) * 2009-11-05 2010-04-21 蚌埠丰原涂山制药有限公司 复方阿替卡因注射用冻干制剂及其制备方法
WO2018220288A1 (fr) * 2017-05-29 2018-12-06 Tauzin Benedicte Vincente Composition injectable stérile contenant de l'acide hyaluronique réticule et de l'articaine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SCHNEIDER G: "[Experiences with carticain in anaesthesia prior to ophthalmic operation]. ERFAHRUNGEN MIT CARTICAIN BEI DER ANAESTHESIE VOR OPHTHALMOLOGISCHEN EINGRIFFEN", BERICHTE DER DEUTSCHEN OPHTHALMOLOGISCHEN GESELLSCHAFT, XX, DE, vol. 78, 1 January 1981 (1981-01-01), pages 909 - 910, XP008007513 *
See also references of WO2020197816A1 *

Also Published As

Publication number Publication date
IL286624A (en) 2021-10-31
JP2022527621A (ja) 2022-06-02
MX2021011589A (es) 2021-12-15
AU2020245203A1 (en) 2021-11-11
BR112021019039A2 (pt) 2021-11-30
EP3946311A1 (en) 2022-02-09
WO2020197816A1 (en) 2020-10-01
KR20210143254A (ko) 2021-11-26
SG11202110423UA (en) 2021-10-28
CN114072139A (zh) 2022-02-18
CA3134531A1 (en) 2020-10-01

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Ipc: A61P 23/02 20060101ALI20221121BHEP

Ipc: A61P 27/02 20060101ALI20221121BHEP

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Ipc: A61K 47/26 20060101ALI20221121BHEP

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