EP3205359B1 - Blood pump system - Google Patents
Blood pump system Download PDFInfo
- Publication number
- EP3205359B1 EP3205359B1 EP16155239.3A EP16155239A EP3205359B1 EP 3205359 B1 EP3205359 B1 EP 3205359B1 EP 16155239 A EP16155239 A EP 16155239A EP 3205359 B1 EP3205359 B1 EP 3205359B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- flow
- blood pump
- blood
- pressure sensor
- pressure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000008280 blood Substances 0.000 title claims description 50
- 210000004369 blood Anatomy 0.000 title claims description 50
- 230000017531 blood circulation Effects 0.000 claims description 25
- 238000004891 communication Methods 0.000 claims description 3
- 210000000709 aorta Anatomy 0.000 description 5
- 210000005242 cardiac chamber Anatomy 0.000 description 5
- 239000013307 optical fiber Substances 0.000 description 5
- 210000005240 left ventricle Anatomy 0.000 description 4
- 238000005086 pumping Methods 0.000 description 4
- 210000002376 aorta thoracic Anatomy 0.000 description 3
- 230000036772 blood pressure Effects 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 230000002792 vascular Effects 0.000 description 3
- 210000001765 aortic valve Anatomy 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 210000003709 heart valve Anatomy 0.000 description 2
- 229910001000 nickel titanium Inorganic materials 0.000 description 2
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- 229920006254 polymer film Polymers 0.000 description 2
- 210000005241 right ventricle Anatomy 0.000 description 2
- 229910001285 shape-memory alloy Inorganic materials 0.000 description 2
- 230000002861 ventricular Effects 0.000 description 2
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000004115 mitral valve Anatomy 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000001020 rhythmical effect Effects 0.000 description 1
- 229920000431 shape-memory polymer Polymers 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/135—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/538—Regulation using real-time blood pump operational parameter data, e.g. motor current
- A61M60/554—Regulation using real-time blood pump operational parameter data, e.g. motor current of blood pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/13—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
- A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
- A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
- A61M60/237—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/403—Details relating to driving for non-positive displacement blood pumps
- A61M60/422—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
- A61M60/81—Pump housings
- A61M60/816—Sensors arranged on or in the housing, e.g. ultrasound flow sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/80—Constructional details other than related to driving
- A61M60/855—Constructional details other than related to driving of implantable pumps or pumping devices
- A61M60/857—Implantable blood tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3327—Measuring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
Definitions
- This invention relates to a blood pump system comprising a blood pump and an intravascular flow cannula that is in flow communication with the blood pump and guides blood from a vessel towards the blood pump.
- the blood pump is an intravascular rotary blood pump which can be placed inside the vessel, such as the left ventricle or right ventricle or the aorta or any other blood vessel, as the case may be.
- the blood pump is driven by a motor which may be outside the patient's body or which may be placed inside the vessel along with the pump.
- the pump is connected to the external motor via a flexible drive cable, whereas in the latter case the pump and the motor are combined to form an integral pumping device and receive energy preferably from outside the patient's body through a catheter.
- the latter structure is the preferred structure for the blood pump system of the present invention, but the present invention is not limited thereto.
- blood pump systems When such blood pump systems are used for temporary heart support, they are introduced percutaneously into the femoral artery for example and guided through the body's vascular system in order to support or replace the pumping action in the heart, for example.
- the flow cannula protrudes through a cardiac valve opening to enable blood to be pumped through the cardiac valve by means of the pump.
- the blood pump system is equipped with pressure sensors externally on the housing of the blood pump and externally on the flow cannula in order to establish the inlet pressure and the outlet pressure. Data regarding the inlet and outlet pressures, together with the power consumption of the electrical motor of the blood pump system, form a set of relevant information for the function and delivery rate of the blood pump system.
- the measured pressures enable inferences to be drawn about the positioning of the blood pump in the vascular system.
- a comparison of the differential pressure with the current power consumption of the motor enables local states as well as cavitation and sucking to be ascertained.
- WO 2013/160407 A1 proposes to provide the blood pump system with two or more than two pressure sensors.
- pressure sensors may be provided externally on the blood pump system at the proximal end of the blood pump and/or at the distal end of the flow cannula.
- An additional pressure sensor may be provided within the flow cannula for determining when the flow cannula is being sucked against a heart chamber wall.
- the object of the present invention is to further improve known blood pump systems in respect of the arrangement of pressure sensors.
- the blood pump system of the present invention comprises a blood pump and an intravascular flow cannula in flow communication with the blood pump and has a pressure sensor arranged at the flow cannula's distal end portion inside the flow cannula in an area of the blood flow through opening or bordering the area of the blood flow through opening.
- the flow cannula's distal end portion is the end portion which is further away, i.e. distal, from the blood pump, and the blood flow through opening at the flow cannula's distal end serves the purpose for blood to enter the flow cannula on its way to the pump or, when the pump is driven in reverse direction, to exit the flow cannula.
- the pressure sensor is arranged within the flow cannula. In this way, when the flow cannula is being sucked against a heart chamber wall or the flow cannula is otherwise displaced, the pressure sensor cannot be covered by the heart chamber wall or blocked in any other way. Therefore, an indication by the pressure sensor that the pressure is about zero or the rhythmical pressure difference of the heart beat quickly decreases is a clear signal that the flow cannula is being sucked against the heart chamber wall, for example.
- the pressure sensor arranged inside the flow cannula can be used, in particular, to serve as a wall suction indicator.
- the same pressure sensor can be used to serve a second purpose, namely to measure or at least approximately measure the pressure external of the flow cannula, such as the pressure inside the left or right ventricle of the heart, as the case may be, because the blood pressure in the area of the blood flow through opening substantially coincides with the blood pressure outside the flow cannula.
- the proposed special location of the pressure sensor makes it possible to do without a separate external pressure sensor on the outside of the flow cannula.
- the blood pump system may be adapted to determine a differential pressure from a first pressure value provided by the pressure sensor arranged within the distal end portion of flow cannula and a second pressure value provided by a second pressure sensor arranged outside the blood pump, e.g. on the blood pump housing.
- Fig. 1 shows a blood pump system having a catheter 10 which, in this example, is introduced into the descending aorta 11 retrograde.
- the descending aorta 11 is part of the aorta 12 which first ascents from the heart and then descents and has the aortic arch 14.
- the aortic valve 15 which connects the left ventricle 16 to the aorta 12 and to which the intravascular blood pump system extends.
- the blood pump system comprises in addition to the catheter 10 a rotary pump 50 fastened at the distal end of a catheter hose 20 and having a motor section 51 and a pump section 52 disposed at an axial distance from the motor section 51, as well as a flow cannula 53 protruding in the distal direction from the inflow end of the pump section 52.
- the flow cannula 53 has a blood flow through opening 54 at its distal end portion EP forming a suction inlet or, if the pump 50 is driven in reverse direction, a blood flow outlet.
- a soft-flexible tip 55 Distally of the through opening 54 there is provided a soft-flexible tip 55, which can be configured for example as a "pigtail" or in a J-shape.
- FIG. 1 only shows two optical fibers 28A, 28B which are attached at the proximal end to an evaluation device 100.
- These optical fibers 28A, 28B are respectively part of optical pressure sensors who's sensor heads 30 and 60 are located externally on the housing of the pump section 52, on the one hand, and internally in the distal end portion EP of the flow cannula 53, on the other hand.
- the pressure transmitted by the sensor head 30 and 60 is converted into electrical signals in the evaluation device 100 and displayed e.g. on a display screen 101.
- the invention is not limited to a rotary pump with integrated motor section 51.
- the motor for driving the pump may be provided externally of the patient and a flexible drive cable may connect the pump with the external motor.
- the measurement of both the aortic pressure by means of the sensor head 60 and the ventricular pressure by means of the sensor head 30 makes possible, in addition to the actual pressure signal, e.g. a contractility measurement by which the recovery of the heart is measured, as well as the establishment of the pressure difference which is used for computing the flow of the pumping device 50.
- the principle of electro-optical pressure measurements as well as the structure and arrangements of the optical fibers is explained in more detail in WO 2013/160407 A1 .
- the present invention differs from that disclosure only in that the pressure sensor 30 is placed at a specific position inside the flow cannula 53, rather than on the flow cannula's external surface, as will be explained hereinafter.
- Fig. 2A shows the distal end portion EP of the flow cannula 53 in more detail according to a preferred embodiment.
- the end portion EP comprises a radial blood flow through opening 54 for blood to enter or, as the case may be, exit the flow cannula 53.
- a frame structure comprising a plurality of struts 58 is provided so as to form a cage which serves two purposes.
- the struts 58 connect the flow conducting part of the flow cannula 53 with the soft-flexible tip 55.
- the cage-forming frame structure prevents the heart chamber wall from being sucked into and blocking the flow cannula 53.
- the struts 58 may generally extend axially, but they may likewise extend helically, cross each other and/or have interconnections. As shown in Fig. 2B , the struts 58 divide the blood flow through opening 54 in separate blood flow openings 54A to 54D. The dashed lines in the area of the blood flow through opening 54A and 54D mark the outer limits of the flow cannula 53 in the area A of the blood flow inlet 54.
- Fig. 2C is a cross-sectional view through the end portion EP.
- the area A surrounded by a dashed line indicates the level of the blood flow through opening 54 or openings 54A to 54D, respectively, with respect to the flow cannula's longitudinal axis 1.
- This is the area where the pressure sensor 30 may be positioned inside the flow cannula.
- the pressure sensor may be placed at a position X, as shown in Fig. 2C and exemplified by pressure sensor 30' which is only schematically shown.
- the pressure sensitive surface 32 of the pressure sensor 30' should be oriented perpendicularly to the longitudinal axis 1 for reasons explained in more detail in WO 2013/160407 A1 , namely to increase measurement accuracy so as to enable highfrequency physiological signals up to 250 Hz to be derived from the signal data.
- the pressure sensor 30 may border area level A.
- it is positioned at a proximal border thereof, as examplified in Fig. 2C by pressure sensors 30" and 30"'.
- pressure sensors 30" and 30' located at positions Y and Z are only schematically shown and their pressure sensitive surfaces 32 are likewise oriented perpendicularly to the longitudinal axis 1. That is, the blood flow through opening 54 or each of the at least one blood flow through openings 54A to 54D, respectively, have a borderline surrounding the through-opening 54 or 54A to 54D, respectively, and said borderline has a proximal portion which, in the embodiment shown in Fig.
- the funnel structure may be formed from a thin film, in particular a thin polymer film. It is preferable to arrange the pressure sensor 30 exactly at the level of the proximal portion 57 of the borderline surrounding the through opening 54 or through openings 54A to 54D, preferably with its pressure sensitive surface, as is shown in Fig. 2C by pressure sensors 30" and 30"'. Thereby, during normal pump operation, the global pressure within the ventricular cavity can be sensed with minimal to no interference with the pump flow. In addition, should suction be present, then the sensor in this preferred position would also be able to detect the negative pressure due to suction, which is a local phenomenon at the inlet.
- the pressure sensor is arranged on and preferably fixed to the frame structure, e.g. to a strut 58.
- the position can be tangentially from the strut 58, as shown by pressure sensor 30" in Fig. 2C , or, more preferably, on a radial inner side of the frame structure, as shown by pressure sensor 30"' in Fig. 2C .
- Fig. 2D shows a specific example of how the pressure sensor 30 may be placed inside the flow cannula 53, corresponding to the position Z of pressure sensor 30"' in Fig. 2C .
- the pressure sensitive surface 32 of pressure sensor 30 borders the level of the blood flow through opening 54 exactly at the proximal portion 57 of the borderline surrounding the through opening 54, which proximal portion 57 is defined by the end face of the funnel structure 56 surrounding the frame structure of the end portion EP.
- the optical fiber 28A, or plurality of fibers is protected within a separate lumen 27 within which it is freely movable.
- the lumen 27 may consist of a polymer, in particular polyurethane, or preferably of nitinol or another shape-memory alloy and is laid along the flexible flow cannula 53 externally. Lumen 27 enters the flow cannula 53 through the funnel structure 56, and the distal end of the optical fiber 28A with the pressure sensor 30 is fixed on a radial inner side of a strut 58.
- an enlarged cross section and, in particular, the funnel shape structure 56 funnelling from distal to proximal is advantageous because the pressure drop in the blood flow along the axis 1 of the flow cannula is less rapid within the funnel shape as compared to the pressure drop inside the non-funnelling rest of the flow cannula 53.
- the struts 58 of the frame structure are made from a shape-memory alloy, such as nitinol, or a shape memory polymer and the funnel structure 56 surrounding the frame structure is made from a flexible material so that, upon insertion of the flow cannula 53 through the patient's vascular system, the frame structure along with the funnel structure 56 has substantially the same diameter as the rest of the flow cannula 53.
- the expanded configuration with enlarged cross section will be assumed after placement of the device when the frame structure reaches body temperature.
- Fig. 3a and 3b illustrate alternative versions of an expandable frame structure defining the inflow cage.
- interconnecting struts 58 are provided between the main struts providing a structure which further divides the inlet/outlet openings 54A-D into smaller openings 54A'-A"'.
- the preferred sensor position marked ZZ in Fig. 3c , would be radially inside the interconnecting struts assembly 58' at a junction of the interconnecting struts 58' and the end face 57 of the funnel structure 56, e.g. the rim of the thin polymer film.
- Fig. 3b the same interconnecting strut assembly 58' is present, and in addition it is likewise provided, e.g. mirrored (58"), on the side of the flexible funnel structure 56.
- mirrored (58") e.g. mirrored
- the inflow end face 57 of the funnel structure 56 can further be structurally improved by locally increasing the thickness of the funnel structure.
- a radially stiffer funnel structure 56 is particularly advantageous in oder to release from cardiac structures after a sucking event.
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Mechanical Engineering (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- External Artificial Organs (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16155239.3A EP3205359B1 (en) | 2016-02-11 | 2016-02-11 | Blood pump system |
ES17704751T ES2814347T3 (es) | 2016-02-11 | 2017-02-10 | Sistema de bomba para sangre |
CN202211473273.9A CN115944844A (zh) | 2016-02-11 | 2017-02-10 | 血泵*** |
EP17704751.1A EP3413948B1 (en) | 2016-02-11 | 2017-02-10 | Blood pump system |
US16/077,097 US11724091B2 (en) | 2016-02-11 | 2017-02-10 | Blood pump system |
JP2018542740A JP6920326B2 (ja) | 2016-02-11 | 2017-02-10 | 血液ポンプシステム |
DK17704751.1T DK3413948T3 (da) | 2016-02-11 | 2017-02-10 | Blodpumpesystem |
KR1020247015644A KR20240070722A (ko) | 2016-02-11 | 2017-02-10 | 혈액 펌프 시스템 |
EP20183477.7A EP3756701A1 (en) | 2016-02-11 | 2017-02-10 | Blood pump system |
CN201910758071.0A CN110624143B (zh) | 2016-02-11 | 2017-02-10 | 血泵*** |
PCT/EP2017/053033 WO2017137578A1 (en) | 2016-02-11 | 2017-02-10 | Blood pump system |
CN201780010577.2A CN108601875B (zh) | 2016-02-11 | 2017-02-10 | 血泵*** |
KR1020187026096A KR102666418B1 (ko) | 2016-02-11 | 2017-02-10 | 혈액 펌프 시스템 |
JP2021121203A JP7219794B2 (ja) | 2016-02-11 | 2021-07-26 | 血液ポンプシステム |
JP2023010875A JP2023038367A (ja) | 2016-02-11 | 2023-01-27 | 血液ポンプシステム |
US18/212,207 US20240024655A1 (en) | 2016-02-11 | 2023-06-21 | Blood pump system |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16155239.3A EP3205359B1 (en) | 2016-02-11 | 2016-02-11 | Blood pump system |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3205359A1 EP3205359A1 (en) | 2017-08-16 |
EP3205359B1 true EP3205359B1 (en) | 2018-08-29 |
Family
ID=55345763
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16155239.3A Active EP3205359B1 (en) | 2016-02-11 | 2016-02-11 | Blood pump system |
EP17704751.1A Active EP3413948B1 (en) | 2016-02-11 | 2017-02-10 | Blood pump system |
EP20183477.7A Pending EP3756701A1 (en) | 2016-02-11 | 2017-02-10 | Blood pump system |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP17704751.1A Active EP3413948B1 (en) | 2016-02-11 | 2017-02-10 | Blood pump system |
EP20183477.7A Pending EP3756701A1 (en) | 2016-02-11 | 2017-02-10 | Blood pump system |
Country Status (8)
Country | Link |
---|---|
US (2) | US11724091B2 (es) |
EP (3) | EP3205359B1 (es) |
JP (3) | JP6920326B2 (es) |
KR (2) | KR20240070722A (es) |
CN (3) | CN110624143B (es) |
DK (1) | DK3413948T3 (es) |
ES (1) | ES2814347T3 (es) |
WO (1) | WO2017137578A1 (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102012207053A1 (de) | 2012-04-27 | 2013-10-31 | Abiomed Europe Gmbh | Intravasale rotationsblutpumpe |
EP3205359B1 (en) * | 2016-02-11 | 2018-08-29 | Abiomed Europe GmbH | Blood pump system |
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CN110624143B (zh) | 2022-11-29 |
EP3756701A1 (en) | 2020-12-30 |
CN108601875B (zh) | 2019-09-27 |
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WO2017137578A1 (en) | 2017-08-17 |
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JP6920326B2 (ja) | 2021-08-18 |
EP3413948A1 (en) | 2018-12-19 |
US11724091B2 (en) | 2023-08-15 |
JP2023038367A (ja) | 2023-03-16 |
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