EP3125851A1 - Récipient de conservation de comprimés - Google Patents

Récipient de conservation de comprimés

Info

Publication number
EP3125851A1
EP3125851A1 EP15713188.9A EP15713188A EP3125851A1 EP 3125851 A1 EP3125851 A1 EP 3125851A1 EP 15713188 A EP15713188 A EP 15713188A EP 3125851 A1 EP3125851 A1 EP 3125851A1
Authority
EP
European Patent Office
Prior art keywords
container
tablet
blister
tablets
blisters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP15713188.9A
Other languages
German (de)
English (en)
Other versions
EP3125851B1 (fr
Inventor
Hubert Bensmann
Karl-Heinz BANNEFELD
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Madaus GmbH
Haupt Pharma Muenster GmbH
Original Assignee
Madaus GmbH
Haupt Pharma Muenster GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Madaus GmbH, Haupt Pharma Muenster GmbH filed Critical Madaus GmbH
Publication of EP3125851A1 publication Critical patent/EP3125851A1/fr
Application granted granted Critical
Publication of EP3125851B1 publication Critical patent/EP3125851B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
    • B65D83/0445—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments
    • B65D83/0463—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments formed in a band or a blisterweb, inserted in a dispensing device or container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/16—Holders for containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers

Definitions

  • the present invention relates to a container 1 for storing medicament tablets, in particular contraceptive tablets, a process for its preparation and its use for storing tablets, in particular contraceptive tablets.
  • Tablets are usually sold in so-called blister packs.
  • Blister packs are product packs that allow the customer or buyer to see the packaged item.
  • the number of tablets per blister can vary depending on the indication and the size of the individual tablets.
  • tablets which have to be taken regularly are often provided in special blister packs which support the maintenance of a regular intake regimen by means of printing, arrangement etc.
  • An example of corresponding blister packs are tablet blisters for contraceptives.
  • blister packs usually have either 21 or 28 tablets.
  • the 21 tablets or the 21 tablets of the 28 tablets contain a combination of estrogen and progestin, resulting in a regular cycle by taking either no tablet or a drug-free tablet for 7 days after 21 days of tablet intake.
  • the last option is that - for the sake of simplicity - one pill is taken each day and the taking break does not inadvertently last longer than 7 days, which would eliminate protection from conception.
  • a pill intake has been established which goes beyond the 21 days of active ingredient administration or over the 28 days with 21 active ingredient-containing tablets and 7 active ingredient-free tablets.
  • long cycle used for this purpose means that after the 21-day intake, the 7-day pause in taking either without tablets or with 7 active ingredient-free tablets is dispensed with. Without break there is no drop in hormone levels and thus no bleeding. The duration of this bleeding-free time can determine the woman in consultation with her treating gynecologist. In most cases, a 12-week dose with a subsequent 7-day, drug-free interval either without a tablet or with 7 drug-free tablets is practiced. For safe use of long-cycle contraceptives, customized blister packs are required.
  • Corresponding packages are known, for example, from WO 2005/023657 A, in which a container for a plurality of blister packs is described.
  • the blister packs are releasably fixed on a rail provided in the container.
  • Corresponding containers which as a rule consist of a plastic, are expensive to manufacture and relatively large, so they are considered unwieldy by the patients.
  • these packaging are environmentally critical due to the plastic material used.
  • WO 2013/160850 A describes a tablet package which is designed in the form of a booklet in which individual tablet blisters are introduced in the form of a magazine page.
  • a disadvantage of this tablet packaging is the size of the tablet packaging, since the individual tablets of tablet blisters are one above the other.
  • the package after use i. Removal of a tablet, not resealable.
  • a similar package for a variety of Tablettenblistem is also known from WO 2009/146932 A.
  • the present invention has the object to provide a container for storing several Tablettenblistem, which is simple and inexpensive to manufacture.
  • the container according to the invention should be suitable in particular for the storage of contraceptive tablets. These objects are preferably achieved by a container 1 which comprises at least two interconnected tablet blisters 2, 3.
  • the container 1 according to the invention is then characterized in that the container 1 is formed from two rectangular cardboard strips 5, 6 between which at least two tablet blisters 2, 3 are arranged such that the rows of tablets of the tablet blisters 2, 3 are substantially parallel and the rectangular cardboard strips 5, 6 are foldable such that the at least two tablet blisters 2, 3 can be arranged side by side in a plane which is spanned by the rectangular structure of the tablet blisters 2, 3, or in parallel one above the other.
  • a container 1 is thus provided in particular for storing at least two tablet blisters 2, 3 which are connected to one another via the cardboard strips 5, 6, between which the tablet blisters 2, 3 are arranged, and between which at least two tablet blisters 2 3, at least two folds 7, 8 of the type are provided, that the two tablet blisters 2, 3 either side by side in a plane which is biased by the rectangular shape of the tablet blisters 2, 3, or vertically above each other with substantially parallel orientation of Tablettenblister 2, 3 can be arranged.
  • the container 1 can be opened or closed to remove a tablet from one of the tablet blisters 2, 3.
  • the tablet blister 2, 3 of the container 1 in a plane which is due to the rectangular shape of the Tablets blister 2, 3 is clamped, are arranged.
  • the open state of the container 1 is shown in Figure 1, while the closed state of the container 1 according to the invention in Figure 2c 4 is shown.
  • the tablet blisters 2, 3 lie vertically one above the other with essentially parallel alignment of the tablet blisters 2, 3.
  • the container 1 comprises three tablet blisters 2, 3, 4, which are arranged between the two cardboard strips 5, 6.
  • the three tablet blisters 2, 3, 4 are arranged side by side in a row, two folds 7, 8, 9, 10 being provided between the respective tablet blisters 2, 3, 4, so that in the opened position
  • the tablets blister 2, 3, 4 in the plane defined by the tablets blister 2, 3, 4 can be arranged side by side and in the closed state, the tablets blister 2, 3, 4 arranged vertically one above the other with substantially parallel orientation of the tablet blister 2, 3, 4 can be.
  • the respective tablet blisters 2, 3, 4 preferably each have 28 tablet chambers 11 for receiving medicament tablets, in particular tablets for contraception.
  • the respective 28 tablet chambers 11 of the at least two tablet blisters 2, 3 are arranged in each case in 4 rows of 7 tablet chambers 11. It is further preferred that the respective 4 rows of the at least two tablet blisters 2, 3 are spaced apart from each other in such a way that a numerical imprint 12 can be applied to the upper cardboard strip 5 between two adjacent rows of tablet chambers 11 of a tablet blister.
  • the individual tablet chambers 11 of the first tablet blister 2 are numbered from 1 to 28.
  • the tablet chambers 11 of the second tablet blister 3 are numbered from 29 to 56.
  • the tablet chambers 11 of the third tablet blister 4, if present, are numbered from 57 to 84.
  • commercially available tablet blisters are used in the container 1.
  • Corresponding tablet blisters are known per se to a person skilled in the art and generally comprise an aluminum-comprising cover film which is provided with an adhesive layer, and a base film or thermoforming film usually produced on the basis of PVC, in which the tablet chambers are formed by deep-drawing. the.
  • FIG. 2 shows the closure of the container 1 according to the invention from the open state 2a through a folded state 2b to a closed state FIG. 2c.
  • FIG. 4 shows a closed container 1 according to the invention with staggered tablet chambers 11 in the blisters 3 and 4.
  • FIG. 1 shows a container 1 according to the invention.
  • three tablet blisters 2, 3, 4 are arranged such that the rows of tablets of the respective tablet blisters 2, 3, 4 run parallel to one another.
  • the tablet blisters 2, 3, 4 are arranged between two cardboard strips 5, 6, visible from FIGS. 2 a to 2 c, which extend laterally beyond the tablet blisters 2, 3, 4 and over the region between the tablet blisters 2, 3, 4 extend. Outside the areas of the tablet blister 2, 3, 4, the cardboard strips 5, 6 are connected to each other, in particular glued.
  • the upper cardboard strip 5 has recesses 22 for the tablet chambers of the respective tablet blisters 2, 3, 4.
  • the cardboard strips have partial regions 13, 14, 15 which are assigned to the respective tablet membranes 2, 3, 4. Between these portions 13, 14, 15 are each two folds 7, 8, 9, 10, which are formed as folded edges. At these folds or folding edges 7, 8, 9, 10, the container 1 can be folded so that the three tablets blister 2, 3, 4 either side by side in a plane which is spanned by the rectangular shape of the tablet blister 2, 3, 4 (Open state of the container 1), or vertically above one another with substantially parallel alignment of the tablet blister 2, 3, 4 can be arranged (closed state of the container 1).
  • the cardboard strip can have a further partial region 16, which adjoins the partial region 13 in the longitudinal direction. Attachment information, stickers or the like may be attached to the subarea 16.
  • the partial regions 13, 14, 15, 16 all have a substantially identical surface, so that when the container 1 is folded along the folds 7, 8, 9, 10, as shown in FIGS. 2a to 2c, a carton-like shaped body in a cuboid shape results
  • the container 1 according to the invention has sufficient space for numbering by numeric printing 12 of the corresponding tablets of the respective tablet blister 2, 3, 4.
  • each tablet blister 2, 3, 4 consists of 28 tablets each, which are arranged in 4 rows of 7 tablets.
  • the tablet blister 2 which is provided in the portion 13, the tablets numbered 1 to 28 from top left to on the lower right.
  • the tablets 29 to 56 which are provided in the tablet blister 3 in the partial area 14
  • the tablets 57 to 84 which are provided in the tablet blister 4 in the partial area 15, likewise from top left to bottom right.
  • Thistientsfbrm is shown in Figure 1.
  • the tablet blister 4 contains in the partial area 15 the tablets 1 to 28, the tablet blister 3 in the partial area 14, the tablets 29 to 56 and the tablet blister 2 in the partial area 13 the tablets 57 to 84, likewise each from top left to bottom right.
  • the tablets 1 to 28 of the tablet blister 4 are first taken by the patient. If the tablets 1 to 28 of the tablet blister 4 are used up, the patient can separate the tablet blister 4 in the partial area 15 along a perforation provided between the tablet blisters 4 and 3 and only needs the tablet blisters 2 and 3 for the remaining revenue regimen. After the tablets 29 have been used to 56 of the tablet blister 3 can then also the portion 14 are separated along the provided between the sections 12 and 13 perforation. As a result, the patient does not have to permanently use the tablet blister 2, 3, 4.
  • the perforations provided for separating the partial regions 14, 15 with the tablet blisters 3, 4 may be provided on the folds 7, 8, 9, 10 or separately therefrom.
  • the sequence of the individual contraceptive tablets on each tablet blister is rotated by 180 °, so that the weekly rows of 7 tablets each are arranged in a consistent sequence 1 to 12.
  • This arrangement of the tablets represents a safe intake by the patient.
  • the container 1 comprises two cardboard strips 5, 6, between which the tablet blisters 2, 3, 4 are inserted.
  • a cardboard or cardboard strip is understood to be any paperboard, paper or plastic material which gives the container 1 sufficient stability.
  • the cardboard strips 5, 6 are integrally formed on both sides of the tablet blisters, wherein said folds 7, 8, 9, 10, 17, 18 are provided between the individual portions 13 to 16 and between the respective portions 14 and 15, which correspond to the tablet blisters 3 and 4, perforations are provided.
  • the cardboard strip 5 is integrally formed and the cardboard strip 6 is composed of three or four individual cardboard strips corresponding to the subregions 13, 14, 15 or 13, 14, 15, 16.
  • the cardboard strip 6 is integrally formed and the cardboard strip 5 is composed of three or four individual cardboard strips corresponding to the subregions 13, 14, 15 or 13, 14, 15, 16.
  • the arrangement of the tablets in the Tablettenblistem 3 and 4 in the sub-areas 14 and 15 is preferably offset, so that when folding the container 1, the tablets of the tablet blister 4 lie in the spaces between the tablets of the Tablettenb- listers 3.
  • the webs 19, 20, 21 between the subregions 13 to 16 can be reduced in size and the space requirement of the container 1 according to the invention in the closed state is reduced overall.
  • a corresponding embodiment of the container 1 according to the invention is shown in FIG.
  • the cardboard strips on the side of the base sheets of the tablet blisters 2, 3, 4 have lockouts 11 corresponding to the tablet compartments. It is preferred that the partial area 16 has at least seven removable strips which can be stuck on again, each of which identifies the seven days of the week and each beginning with a different day of the week.
  • each 3 adhesive strips start on the same day of the week and the respective adhesive strips are then mounted above the tablet blister 2, 3, 4.
  • the partial region 16 is provided with a tongue 24, with which the container 1 is closed after folding in the partial regions 13, 14, 15 adjoining the partial region 16 by introduction into a corresponding recess 26, for example in the fold 8 can be.
  • the container 1 has a seal which is such that only by visible destruction of the seal, the tongue 24 can be removed from the recess 26.
  • a further subject of the present invention is a method for producing the container 1 described above.
  • the container 1 according to the invention was produced such that in a first method step a cardboard strip 5 with recesses 22 and an adhesive coating applied on the back is provided in a second method step provided a cardboard strip 6 of the same size and in a third process step, the two cardboard strips 5, 6 with simultaneous fixation of the tablet blister 2, 3, 4 connected to each other, in particular glued be.
  • the folds 7 to 10 and 17 and 18 and the optionally provided perforations between the subregions 13 to 15 in the region of the webs 19, 20, 21 can in this case on the cardboard strips 5, 6 before merging the cardboard strips 5, 6 or subsequently after merging the cardboard strip 5, 6 are provided.
  • the Perforations can also be provided on the folds 7, 8, 9, 10.
  • FIG. 5 shows a commercially available blister 2, 3, 4 with tablet chambers 11, which are used in the container 1 according to the invention.
  • FIG. 6 shows the modular construction of the container 1 according to the invention.
  • Three cardboard blisters 2, 3, 4 are arranged on a cardboard strip 6 and a cardboard strip 5 provided with corresponding recesses is fixed onto the cardboard strip 6 via the tablet blisters.
  • the container 1 according to the invention is particularly suitable for the storage of contraceptive tablets, which are taken over a longer period of time, for example 12 weeks.
  • the containers shown in Figures 1, 3a and 3b are provided with a total of 84 Tablettenkammem.
  • the container according to the invention additionally contains 7 placebo tablets. Therefore, the container according to the invention preferably each has the third tablet blister with 35 Tablettenkammem instead of 28 tablet chambers.
  • FIGS. 7a to 7c which, with the exception of the other tablet chambers for the placebo tablets, correspond to the embodiments of FIGS. 1, 3a and 3b.
  • the present invention relates to the use of such a container for storing tablets, in particular contraceptives.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Informatics (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)

Abstract

L'invention concerne un récipient (1), servant à conserver des comprimés médicaux, en particulier des pilules contraceptives, qui comporte au moins deux emballages sous blister (2, 3).
EP15713188.9A 2014-03-31 2015-03-27 Utilisation d'un récipient pour la conservation de comprimés contraceptifs Active EP3125851B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102014205944 2014-03-31
PCT/EP2015/056723 WO2015150259A1 (fr) 2014-03-31 2015-03-27 Récipient de conservation de comprimés

Publications (2)

Publication Number Publication Date
EP3125851A1 true EP3125851A1 (fr) 2017-02-08
EP3125851B1 EP3125851B1 (fr) 2018-11-28

Family

ID=52779657

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15713188.9A Active EP3125851B1 (fr) 2014-03-31 2015-03-27 Utilisation d'un récipient pour la conservation de comprimés contraceptifs

Country Status (3)

Country Link
EP (1) EP3125851B1 (fr)
ES (1) ES2706278T3 (fr)
WO (1) WO2015150259A1 (fr)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8518828D0 (en) * 1985-07-25 1985-08-29 American Home Prod Tablet package
US5954202A (en) * 1996-06-28 1999-09-21 Westvaco Corporation Paperboard blank for a self-contained, reclosable package
SE508758C2 (sv) * 1997-02-19 1998-11-02 Jakob Ehrensvaerd Registreringsanordning
US7726480B2 (en) * 2005-08-24 2010-06-01 Winterborne, Inc. Display pack and packaging method and apparatus
US20080093253A1 (en) * 2006-10-23 2008-04-24 Gail Halko Medication Dispensing Package
US7896161B2 (en) * 2008-01-15 2011-03-01 Anderson Packaging, Inc. Child-resistant, senior friendly carded package and method of assembly
WO2013128459A1 (fr) * 2012-03-01 2013-09-06 2P2D Solutions Ltd. Chaîne blister repliée, machine de pliage et procédé de pliage

Also Published As

Publication number Publication date
ES2706278T3 (es) 2019-03-28
WO2015150259A1 (fr) 2015-10-08
EP3125851B1 (fr) 2018-11-28

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