EP2662065B1 - Verblindungsvorrichtung - Google Patents
Verblindungsvorrichtung Download PDFInfo
- Publication number
- EP2662065B1 EP2662065B1 EP13164845.3A EP13164845A EP2662065B1 EP 2662065 B1 EP2662065 B1 EP 2662065B1 EP 13164845 A EP13164845 A EP 13164845A EP 2662065 B1 EP2662065 B1 EP 2662065B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- container
- blinding
- lid
- closure
- opening
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000002360 preparation method Methods 0.000 claims description 8
- 238000000605 extraction Methods 0.000 claims 1
- 239000002775 capsule Substances 0.000 description 4
- 230000007704 transition Effects 0.000 description 4
- 201000004569 Blindness Diseases 0.000 description 1
- 244000197960 Galium verum Species 0.000 description 1
- 230000004323 axial length Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1412—Containers with closing means, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/16—Holders for containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/18—Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
- B65D77/04—Articles or materials enclosed in two or more containers disposed one within another
- B65D77/048—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid and the outer container being of curved cross-section, e.g. cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1406—Septums, pierceable membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2251/00—Details relating to container closures
- B65D2251/0003—Two or more closures
- B65D2251/0006—Upper closure
- B65D2251/0015—Upper closure of the 41-type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2251/00—Details relating to container closures
- B65D2251/0003—Two or more closures
- B65D2251/0068—Lower closure
- B65D2251/0078—Lower closure of the 41-type
Definitions
- the invention relates to a device for blinding containers for clinical trials.
- container or small container vials are used, in which usually preparations, i. usually liquid drugs, are provided for clinical trials.
- a shell for a product is for example from the US 2007/0163914 known.
- the blinding sheath described herein is a rigid, hard shell shell, in contrast to known easily deformable sheaths.
- the blinding sheath 1 for a container 2 consists of a middle part 3, a bottom 4 inserted at the lower end of the middle part and a lid 5 arranged on the upper side of the middle part 5.
- the central part 3 has a cylindrical lower portion with a diameter which is larger than the diameter of the container.
- the middle part is tapered to a smaller diameter.
- the upper area is offset laterally with respect to the axis of the lower area with its axis. in such a way that the transition between the lower and the upper region of the central part is strong on one side, left in the figures, and only slightly inclined in relation to each other. In between, there is a uniform course of the slope.
- a circumferential groove 6 On the outside of the upper portion of the central part of a circumferential groove 6 is formed, which is provided on the side of the steeply inclined transition and opposite each with a downward branch. The function of this groove and its branches will be described below together with the function of the lid 5.
- the container is arranged eccentrically on the side of the steeply inclined transition of the middle part.
- a support in the manner of a false bottom 7 with an opening 8 and a circumferential, downwardly directed skirt 9, which is on the side of the steeply inclined transition into the wall of the upper area passes.
- Through the opening extends the neck of the container with its tapered area being held by the lower edge of the skirt.
- the underside of the container is fixed in this position by the bottom 4, which for this purpose on the one hand has an upward thickening 10, through which the container is pressed up against the lower edge of the skirt, and on the other hand with an upstanding Edge 11 is provided for lateral fixation of the container.
- the bottom is pressed after the introduction of the container in the lower opening of the middle part.
- Containers whose diameter over their entire axial length is not or only slightly larger than that of the closure capsule can not be fixed in this way in the shell.
- suitable webs can be arranged in the interior of the casing and / or the casing can consist, for example, of two half-shells separated in the longitudinal direction.
- the cover 5 consists of a top cover 12 corresponding to the upper opening of the middle part and a skirt 13 which extends downwards and embraces the upper edge of the middle part. Near the lower edge of the skirt two inwardly directed cams 14 are arranged, arranged opposite one another. which engage in the groove 6 described above. By this engagement, the lid is connected to the middle part. As the cams engage the downward branches, the lid can be moved axially with respect to the central portion. In its upper position, the lid can be rotated relative to the central part by the cams are guided in the circumferential groove.
- a plurality of gripping elements 15 are mounted in the form of hooks which engage under the cap of the container.
- a removal point in the present case provided with a tubular downwardly extending extension 17 through opening 16, for a removal needle for removal of a Amount of preparation from the container.
- the through-opening can be closed by an elastic plug or the like, which is pierced with the needle for removal.
- FIG. 1 The arrangement shown represents the situation of the blinded container for storage, transportation, etc., ie for the provision for the purpose of a clinical study.
- the cams of the lid are located at the lower ends of the branches of the circumferential groove.
- the lid, as in Fig. 2 shown as far as raised until the cams 14 to the height of the revolving Pass groove.
- the cap With the lifting of the lid, the cap is lifted off the container by the gripping elements.
- the next step is to remove the lid with the capsule removed from the container, as in Fig.
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Closures For Containers (AREA)
- Sampling And Sample Adjustment (AREA)
- Sewing Machines And Sewing (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH00637/12A CH706482A1 (de) | 2012-05-08 | 2012-05-08 | Verblindungsvorrichtung. |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2662065A1 EP2662065A1 (de) | 2013-11-13 |
EP2662065B1 true EP2662065B1 (de) | 2015-03-04 |
Family
ID=47115064
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13164845.3A Active EP2662065B1 (de) | 2012-05-08 | 2013-04-23 | Verblindungsvorrichtung |
Country Status (5)
Country | Link |
---|---|
US (1) | US9192543B2 (es) |
EP (1) | EP2662065B1 (es) |
CH (1) | CH706482A1 (es) |
DK (1) | DK2662065T3 (es) |
ES (1) | ES2546561T3 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201412065D0 (en) * | 2014-07-07 | 2014-08-20 | Moore Kenneth S A | A masking package |
CN107804563B (zh) * | 2017-11-01 | 2019-11-12 | 范小丽 | 一种医用滴眼液辅助包装盒 |
CN107822770B (zh) * | 2017-11-01 | 2020-04-14 | 莱芜职业技术学院 | 一种医用滴眼液辅助支架 |
US11542083B2 (en) | 2019-09-30 | 2023-01-03 | Fisher Clinical Services, Inc. | Vial blinding assemblies and methods of assembly |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2438906A (en) * | 1945-04-21 | 1948-04-06 | William D Elsas | Closure |
US2750066A (en) * | 1953-07-10 | 1956-06-12 | Adela F Shekter | Pocket flasks |
AU441022B2 (en) * | 1970-07-14 | 1973-09-28 | Fmc Corporation | An improved capsule for containing an article (divisional of 408,028) |
US4949858A (en) * | 1989-06-19 | 1990-08-21 | Ethylene Corp. | Sample bottle and cap therefor |
US5143261A (en) * | 1989-12-20 | 1992-09-01 | The Procter & Gamble Company | Multi-compartment container for proportional dispensing of a plurality of liquids |
US5590782A (en) * | 1995-04-17 | 1997-01-07 | Habley Medical Technology Corporation | Vial holder assembly |
GB0029752D0 (en) * | 2000-12-06 | 2001-01-17 | Lilly Industries Ltd | A protective container and a package comprising a protective container |
US20070163914A1 (en) * | 2005-09-22 | 2007-07-19 | Gehring Debra G | Package closure |
US8875926B2 (en) * | 2012-03-16 | 2014-11-04 | Valon Grajqevci | Resealable multi-compartment beverage container |
-
2012
- 2012-05-08 CH CH00637/12A patent/CH706482A1/de not_active Application Discontinuation
-
2013
- 2013-04-12 US US13/861,709 patent/US9192543B2/en active Active
- 2013-04-23 EP EP13164845.3A patent/EP2662065B1/de active Active
- 2013-04-23 ES ES13164845.3T patent/ES2546561T3/es active Active
- 2013-04-23 DK DK13164845.3T patent/DK2662065T3/en active
Also Published As
Publication number | Publication date |
---|---|
CH706482A1 (de) | 2013-11-15 |
DK2662065T3 (en) | 2015-06-08 |
US20130299446A1 (en) | 2013-11-14 |
US9192543B2 (en) | 2015-11-24 |
EP2662065A1 (de) | 2013-11-13 |
ES2546561T3 (es) | 2015-09-24 |
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