EP1833511A4 - Verfahren zur behandlung von hirnkrebs - Google Patents
Verfahren zur behandlung von hirnkrebsInfo
- Publication number
- EP1833511A4 EP1833511A4 EP06717342A EP06717342A EP1833511A4 EP 1833511 A4 EP1833511 A4 EP 1833511A4 EP 06717342 A EP06717342 A EP 06717342A EP 06717342 A EP06717342 A EP 06717342A EP 1833511 A4 EP1833511 A4 EP 1833511A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- brain cancer
- treating brain
- treating
- cancer
- brain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 208000003174 Brain Neoplasms Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64126305P | 2005-01-03 | 2005-01-03 | |
PCT/US2006/000122 WO2006074187A2 (en) | 2005-01-03 | 2006-01-03 | Method of treating brain cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1833511A2 EP1833511A2 (de) | 2007-09-19 |
EP1833511A4 true EP1833511A4 (de) | 2011-01-19 |
Family
ID=36648123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06717342A Withdrawn EP1833511A4 (de) | 2005-01-03 | 2006-01-03 | Verfahren zur behandlung von hirnkrebs |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1833511A4 (de) |
JP (1) | JP2008526776A (de) |
KR (1) | KR20070117547A (de) |
CN (1) | CN101287369A (de) |
AU (1) | AU2006204052A1 (de) |
CA (1) | CA2592971A1 (de) |
WO (1) | WO2006074187A2 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1684762A4 (de) | 2003-11-13 | 2009-06-17 | Ambit Biosciences Corp | Harnstoff-derivate als kinase-modulatoren |
WO2008124824A1 (en) * | 2007-04-10 | 2008-10-16 | Myriad Genetics, Inc. | Dosages and methods for the treatment of cancer |
NZ580866A (en) * | 2007-04-10 | 2011-02-25 | Myriad Pharmaceuticals Inc | Method of treating brain cancer |
FR2932180B1 (fr) * | 2008-06-04 | 2012-08-10 | Centre Nat Rech Scient | Dihydro iso ca-4 et analogues : puissants cytotoxiques, inhibiteurs de la polymerisation de la tubuline |
SG193262A1 (en) | 2011-03-15 | 2013-10-30 | Chiesi Farma Spa | Isoxazolidine derivatives |
KR20140039161A (ko) | 2011-03-15 | 2014-04-01 | 키에시 파르마슈티시 엣스. 피. 에이. | 이소옥사졸리딘 유도체 |
FR3019819B1 (fr) | 2014-04-09 | 2018-03-23 | Centre National De La Recherche Scientifique (Cnrs) | Composes cytotoxiques inhibiteurs de la polymerisation de la tubuline |
US20220235013A1 (en) | 2017-03-21 | 2022-07-28 | Bayer Pharma Aktiengesellschaft | 2-methyl-quinazolines |
CA3097231A1 (en) | 2018-04-18 | 2019-10-24 | Bayer Pharma Aktiengesellschaft | 2-methyl-aza-quinazolines |
FR3080620B1 (fr) | 2018-04-27 | 2021-11-12 | Univ Paris Sud | Composes a activite inhibitrice de la polymerisation de la tubuline et aux proprietes immunomodulatrices |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992014716A1 (en) * | 1991-02-20 | 1992-09-03 | Pfizer Inc. | 2,4-diaminoquinazolines derivatives for enhancing antitumor activity |
WO2005003100A2 (en) * | 2003-07-03 | 2005-01-13 | Myriad Genetics, Inc. | 4-arylamino-quinazolines as activators of caspases and inducers of apoptosis |
WO2006014420A1 (en) * | 2004-07-06 | 2006-02-09 | Angion Biomedica Corporation | Quinazoline modulators of hepatocyte growth factor / c-met activity for the treatment of cancer |
WO2006074147A2 (en) * | 2005-01-03 | 2006-07-13 | Myriad Genetics, Inc. | Nitrogen containing bicyclic compounds and therapeutical use thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL88507A (en) * | 1987-12-03 | 1993-02-21 | Smithkline Beckman Intercredit | 2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them |
CA2265630A1 (en) * | 1996-09-13 | 1998-03-19 | Gerald Mcmahon | Use of quinazoline derivatives for the manufacture of a medicament in the treatment of hyperproliferative skin disorders |
HUP0102793A3 (en) * | 1998-05-28 | 2002-07-29 | Parker Hughes Inst St Paul | Quinazolines for treating brain tumor and medicaments containing them |
UA71945C2 (en) * | 1999-01-27 | 2005-01-17 | Pfizer Prod Inc | Substituted bicyclic derivatives being used as anticancer agents |
-
2006
- 2006-01-03 CN CNA2006800025252A patent/CN101287369A/zh active Pending
- 2006-01-03 WO PCT/US2006/000122 patent/WO2006074187A2/en active Application Filing
- 2006-01-03 CA CA002592971A patent/CA2592971A1/en not_active Abandoned
- 2006-01-03 AU AU2006204052A patent/AU2006204052A1/en not_active Abandoned
- 2006-01-03 EP EP06717342A patent/EP1833511A4/de not_active Withdrawn
- 2006-01-03 JP JP2007549710A patent/JP2008526776A/ja active Pending
- 2006-01-03 KR KR1020077017960A patent/KR20070117547A/ko not_active Application Discontinuation
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992014716A1 (en) * | 1991-02-20 | 1992-09-03 | Pfizer Inc. | 2,4-diaminoquinazolines derivatives for enhancing antitumor activity |
WO2005003100A2 (en) * | 2003-07-03 | 2005-01-13 | Myriad Genetics, Inc. | 4-arylamino-quinazolines as activators of caspases and inducers of apoptosis |
WO2006014420A1 (en) * | 2004-07-06 | 2006-02-09 | Angion Biomedica Corporation | Quinazoline modulators of hepatocyte growth factor / c-met activity for the treatment of cancer |
WO2006074147A2 (en) * | 2005-01-03 | 2006-07-13 | Myriad Genetics, Inc. | Nitrogen containing bicyclic compounds and therapeutical use thereof |
Non-Patent Citations (2)
Title |
---|
ASSEFA, HAREGEWEIN ET AL: "3D-QSAR and docking studies on 4-anilinoquinazoline and 4-anilinoquinoline epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors", JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN , 17(8), 475-493 CODEN: JCADEQ; ISSN: 0920-654X, 2003, XP002613543 * |
RACHID, ZAKARIA ET AL: "The Combi-Targeting Concept: Chemical Dissection of the Dual Targeting Properties of a Series of "Combi-Triazenes"", JOURNAL OF MEDICINAL CHEMISTRY , 46(20), 4313-4321 CODEN: JMCMAR; ISSN: 0022-2623, 2003, XP002613544 * |
Also Published As
Publication number | Publication date |
---|---|
AU2006204052A1 (en) | 2006-07-13 |
WO2006074187A3 (en) | 2008-01-10 |
CN101287369A (zh) | 2008-10-15 |
JP2008526776A (ja) | 2008-07-24 |
CA2592971A1 (en) | 2006-07-13 |
EP1833511A2 (de) | 2007-09-19 |
KR20070117547A (ko) | 2007-12-12 |
WO2006074187A2 (en) | 2006-07-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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Effective date: 20070629 |
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REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1102261 Country of ref document: HK |
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R17D | Deferred search report published (corrected) |
Effective date: 20080110 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/517 20060101ALI20080124BHEP Ipc: A01N 43/54 20060101AFI20080124BHEP |
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DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20101222 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 35/00 20060101ALI20101213BHEP Ipc: A61K 31/4706 20060101ALI20101213BHEP Ipc: A61K 31/5377 20060101ALI20101213BHEP Ipc: A61K 31/517 20060101ALI20101213BHEP Ipc: A01N 43/54 20060101AFI20080124BHEP |
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