EP1833511A4 - Methode de traitement du cancer du cerveau - Google Patents

Methode de traitement du cancer du cerveau

Info

Publication number
EP1833511A4
EP1833511A4 EP06717342A EP06717342A EP1833511A4 EP 1833511 A4 EP1833511 A4 EP 1833511A4 EP 06717342 A EP06717342 A EP 06717342A EP 06717342 A EP06717342 A EP 06717342A EP 1833511 A4 EP1833511 A4 EP 1833511A4
Authority
EP
European Patent Office
Prior art keywords
brain cancer
treating brain
treating
cancer
brain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06717342A
Other languages
German (de)
English (en)
Other versions
EP1833511A2 (fr
Inventor
Sui Xiong Cai
Mark B Anderson
Adam Willardsen
Nilantha Sudath Sirisoma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Myriad Genetics Inc
Cytovia Therapeutics LLC
Original Assignee
Myriad Genetics Inc
Cytovia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Myriad Genetics Inc, Cytovia Inc filed Critical Myriad Genetics Inc
Publication of EP1833511A2 publication Critical patent/EP1833511A2/fr
Publication of EP1833511A4 publication Critical patent/EP1833511A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
EP06717342A 2005-01-03 2006-01-03 Methode de traitement du cancer du cerveau Withdrawn EP1833511A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64126305P 2005-01-03 2005-01-03
PCT/US2006/000122 WO2006074187A2 (fr) 2005-01-03 2006-01-03 Methode de traitement du cancer du cerveau

Publications (2)

Publication Number Publication Date
EP1833511A2 EP1833511A2 (fr) 2007-09-19
EP1833511A4 true EP1833511A4 (fr) 2011-01-19

Family

ID=36648123

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06717342A Withdrawn EP1833511A4 (fr) 2005-01-03 2006-01-03 Methode de traitement du cancer du cerveau

Country Status (7)

Country Link
EP (1) EP1833511A4 (fr)
JP (1) JP2008526776A (fr)
KR (1) KR20070117547A (fr)
CN (1) CN101287369A (fr)
AU (1) AU2006204052A1 (fr)
CA (1) CA2592971A1 (fr)
WO (1) WO2006074187A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7750160B2 (en) 2003-11-13 2010-07-06 Ambit Biosciences Corporation Isoxazolyl urea derivatives as kinase modulators
CN101742910A (zh) * 2007-04-10 2010-06-16 美瑞德制药公司 治疗脑癌的方法
CA2720987A1 (fr) * 2007-04-10 2008-10-16 Myrexis, Inc. Doses et methodes de traitement du cancer
FR2932180B1 (fr) * 2008-06-04 2012-08-10 Centre Nat Rech Scient Dihydro iso ca-4 et analogues : puissants cytotoxiques, inhibiteurs de la polymerisation de la tubuline
MX345400B (es) 2011-03-15 2017-01-30 Chiesi Farm Spa Derivados de isoxazolidina.
RU2013141933A (ru) 2011-03-15 2015-03-20 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Производные изоксазолидина
FR3019819B1 (fr) * 2014-04-09 2018-03-23 Centre National De La Recherche Scientifique (Cnrs) Composes cytotoxiques inhibiteurs de la polymerisation de la tubuline
US20220235013A1 (en) 2017-03-21 2022-07-28 Bayer Pharma Aktiengesellschaft 2-methyl-quinazolines
US20220274979A1 (en) 2018-04-18 2022-09-01 Bayer Pharma Aktiengesellschaft 2-methyl-aza-quinazolines
FR3080620B1 (fr) 2018-04-27 2021-11-12 Univ Paris Sud Composes a activite inhibitrice de la polymerisation de la tubuline et aux proprietes immunomodulatrices

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992014716A1 (fr) * 1991-02-20 1992-09-03 Pfizer Inc. Derives de 2,4-diaminoquinazolines stimulant l'activite anti-tumorale
WO2005003100A2 (fr) * 2003-07-03 2005-01-13 Myriad Genetics, Inc. Composes et leur utilisation therapeutique
WO2006014420A1 (fr) * 2004-07-06 2006-02-09 Angion Biomedica Corporation Modulateurs quinazoline d'activite de facteur de croissance hepatocyte/c-met permettant de traiter le cancer
WO2006074147A2 (fr) * 2005-01-03 2006-07-13 Myriad Genetics, Inc. Composes et utilisation therapeutique associee

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL88507A (en) * 1987-12-03 1993-02-21 Smithkline Beckman Intercredit 2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them
CA2265630A1 (fr) * 1996-09-13 1998-03-19 Gerald Mcmahon Utilisation de derives de la quinazoline pour la fabrication d'un medicament destine au traitement de troubles cutanes hyperproliferatifs
AU4317399A (en) * 1998-05-28 1999-12-13 Parker Hughes Institute Quinazolines for treating brain tumor
UA71945C2 (en) * 1999-01-27 2005-01-17 Pfizer Prod Inc Substituted bicyclic derivatives being used as anticancer agents

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992014716A1 (fr) * 1991-02-20 1992-09-03 Pfizer Inc. Derives de 2,4-diaminoquinazolines stimulant l'activite anti-tumorale
WO2005003100A2 (fr) * 2003-07-03 2005-01-13 Myriad Genetics, Inc. Composes et leur utilisation therapeutique
WO2006014420A1 (fr) * 2004-07-06 2006-02-09 Angion Biomedica Corporation Modulateurs quinazoline d'activite de facteur de croissance hepatocyte/c-met permettant de traiter le cancer
WO2006074147A2 (fr) * 2005-01-03 2006-07-13 Myriad Genetics, Inc. Composes et utilisation therapeutique associee

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ASSEFA, HAREGEWEIN ET AL: "3D-QSAR and docking studies on 4-anilinoquinazoline and 4-anilinoquinoline epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors", JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN , 17(8), 475-493 CODEN: JCADEQ; ISSN: 0920-654X, 2003, XP002613543 *
RACHID, ZAKARIA ET AL: "The Combi-Targeting Concept: Chemical Dissection of the Dual Targeting Properties of a Series of "Combi-Triazenes"", JOURNAL OF MEDICINAL CHEMISTRY , 46(20), 4313-4321 CODEN: JMCMAR; ISSN: 0022-2623, 2003, XP002613544 *

Also Published As

Publication number Publication date
CA2592971A1 (fr) 2006-07-13
EP1833511A2 (fr) 2007-09-19
WO2006074187A2 (fr) 2006-07-13
KR20070117547A (ko) 2007-12-12
JP2008526776A (ja) 2008-07-24
WO2006074187A3 (fr) 2008-01-10
AU2006204052A1 (en) 2006-07-13
CN101287369A (zh) 2008-10-15

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