EP1379132A4 - Proteines secretees humaines - Google Patents

Proteines secretees humaines

Info

Publication number
EP1379132A4
EP1379132A4 EP02760994A EP02760994A EP1379132A4 EP 1379132 A4 EP1379132 A4 EP 1379132A4 EP 02760994 A EP02760994 A EP 02760994A EP 02760994 A EP02760994 A EP 02760994A EP 1379132 A4 EP1379132 A4 EP 1379132A4
Authority
EP
European Patent Office
Prior art keywords
secreted proteins
human secreted
human
proteins
secreted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02760994A
Other languages
German (de)
English (en)
Other versions
EP1379132A2 (fr
Inventor
Craig A Rosen
Steven M Ruben
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP1379132A2 publication Critical patent/EP1379132A2/fr
Publication of EP1379132A4 publication Critical patent/EP1379132A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP02760994A 2001-03-21 2002-03-19 Proteines secretees humaines Withdrawn EP1379132A4 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US27734001P 2001-03-21 2001-03-21
US277340P 2001-03-21
US30617101P 2001-07-19 2001-07-19
US306171P 2001-07-19
US33128701P 2001-11-13 2001-11-13
US331287P 2001-11-13
PCT/US2002/008278 WO2002102994A2 (fr) 2001-03-21 2002-03-19 Proteines secretees humaines

Publications (2)

Publication Number Publication Date
EP1379132A2 EP1379132A2 (fr) 2004-01-14
EP1379132A4 true EP1379132A4 (fr) 2009-07-01

Family

ID=27402891

Family Applications (7)

Application Number Title Priority Date Filing Date
EP02760994A Withdrawn EP1379132A4 (fr) 2001-03-21 2002-03-19 Proteines secretees humaines
EP02759068A Withdrawn EP1404702A4 (fr) 2001-03-21 2002-03-19 Proteines secretees humaines
EP02782476A Withdrawn EP1414845A4 (fr) 2001-03-21 2002-03-19 Proteines humaines secretees
EP02749512A Withdrawn EP1381622A2 (fr) 2001-03-21 2002-03-19 Proteines secretees par les humains
EP02799146A Withdrawn EP1390390A4 (fr) 2001-03-21 2002-03-19 Proteines secretees humaines
EP02780789A Withdrawn EP1423134A2 (fr) 2001-03-21 2002-03-19 Proteines secretees par l'homme
EP02723499A Withdrawn EP1379264A4 (fr) 2001-03-21 2002-03-19 Proteines humaines secretees

Family Applications After (6)

Application Number Title Priority Date Filing Date
EP02759068A Withdrawn EP1404702A4 (fr) 2001-03-21 2002-03-19 Proteines secretees humaines
EP02782476A Withdrawn EP1414845A4 (fr) 2001-03-21 2002-03-19 Proteines humaines secretees
EP02749512A Withdrawn EP1381622A2 (fr) 2001-03-21 2002-03-19 Proteines secretees par les humains
EP02799146A Withdrawn EP1390390A4 (fr) 2001-03-21 2002-03-19 Proteines secretees humaines
EP02780789A Withdrawn EP1423134A2 (fr) 2001-03-21 2002-03-19 Proteines secretees par l'homme
EP02723499A Withdrawn EP1379264A4 (fr) 2001-03-21 2002-03-19 Proteines humaines secretees

Country Status (4)

Country Link
EP (7) EP1379132A4 (fr)
AU (6) AU2002320013A1 (fr)
CA (7) CA2441840A1 (fr)
WO (7) WO2003004622A2 (fr)

Families Citing this family (80)

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US7196164B2 (en) 1997-07-08 2007-03-27 Human Genome Sciences, Inc. Secreted protein HHTLF25
JP2002513295A (ja) 1997-07-08 2002-05-08 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド 123種類のヒト分泌タンパク質
US20060052321A1 (en) 2002-04-05 2006-03-09 Raitano Arthur B Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
US20040141975A1 (en) 1998-06-01 2004-07-22 Raitano Arthur B. Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
US20030149531A1 (en) 2000-12-06 2003-08-07 Hubert Rene S. Serpentine transmembrane antigens expressed in human cancers and uses thereof
PT1086223E (pt) 1998-06-01 2009-11-03 Agensys Inc Novos antigénios transmembranares em serpentina expressos em cancros humanos e suas utilizações
US6833438B1 (en) 1999-06-01 2004-12-21 Agensys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof
WO2000042073A1 (fr) 1999-01-15 2000-07-20 Biogen, Inc. Antagonistes de la proteine tweak et du recepteur de tweak, et leur utilisation pour traiter des affections immunitaires
EP1666490A3 (fr) * 2000-07-25 2006-11-02 Genentech, Inc. Polypeptides sécrétés et transmembranaires ainsi que les acides nucléiques codant pour ceux-ci
US7291719B2 (en) 2000-07-25 2007-11-06 Genentech, Inc. PRO4332 antibodies
EP1364021A2 (fr) 2000-10-31 2003-11-26 Diadexus, Inc. Compositions et methodes associees a des genes et a des proteines specifiques du colon
US20020111302A1 (en) * 2000-11-30 2002-08-15 Y. Tom Tang Novel nucleic acids and polypeptides
US7736654B2 (en) * 2001-04-10 2010-06-15 Agensys, Inc. Nucleic acids and corresponding proteins useful in the detection and treatment of various cancers
US20030119112A1 (en) 2001-06-20 2003-06-26 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
ES2532757T3 (es) 2001-09-06 2015-03-31 Agensys, Inc. Ácido nucleico y proteína correspondiente denominados STEAP-1 útiles en el tratamiento y la detección de cáncer
WO2003033727A1 (fr) 2001-10-12 2003-04-24 Yamanouchi Pharmaceutical Co., Ltd. Procede de criblage d'un inhibiteur de la mort cellulaire
CA2887716C (fr) 2002-04-09 2017-01-24 Biogen Idec Ma Inc. Procede pour traiter les etats lies a tweak
AU2003900747A0 (en) * 2003-02-18 2003-03-06 Garvan Institute Of Medical Research Diagnosis and treatment of pancreatic cancer
US7709610B2 (en) 2003-05-08 2010-05-04 Facet Biotech Corporation Therapeutic use of anti-CS1 antibodies
US20050025763A1 (en) 2003-05-08 2005-02-03 Protein Design Laboratories, Inc. Therapeutic use of anti-CS1 antibodies
WO2005019258A2 (fr) * 2003-08-11 2005-03-03 Genentech, Inc. Compositions et methodes de traitement de maladies relatives au systeme immunitaire
EP1670947B1 (fr) 2003-09-23 2015-04-01 University Of North Carolina At Chapel Hill Technique et composition de correlation de polymorphisme nucleotidique simple dans le gene vitamine k epoxyde reductase et le dosage de warfarine
JP4777251B2 (ja) * 2003-10-14 2011-09-21 バクスター・インターナショナル・インコーポレイテッド ビタミンkエポキシド還元酵素複合体サブユニット1vkorc1、クマリンおよびその誘導体の治療標的
EP1714154A2 (fr) * 2004-02-03 2006-10-25 Bayer HealthCare AG Agents diagnostiques et therapeutiques pour des maladies associes a la glutamate carboxypeptidase (pgcp) plasmatique
US20050186577A1 (en) 2004-02-20 2005-08-25 Yixin Wang Breast cancer prognostics
AU2004319915B9 (en) 2004-04-22 2011-12-22 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
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WO2006026808A1 (fr) * 2004-09-07 2006-03-16 Telethon Institute For Child Health Research Methode de diagnostic et/ou de prediction du developpement d'une affection allergique
JP2008512099A (ja) * 2004-09-07 2008-04-24 テレソン インスティテュート フォー チャイルド ヘルス リサーチ アレルギー性疾患の処置または予防のための物質
AU2006214179A1 (en) 2005-02-17 2006-08-24 Biogen Idec Ma Inc. Treating neurological disorders
CN101124320A (zh) 2005-02-28 2008-02-13 巴克斯特国际公司 重组共表达维生素k环氧化物还原酶亚基1以提高依赖维生素k的蛋白质表达
EP1861499A4 (fr) 2005-03-15 2008-09-03 Univ North Carolina Procédés et compositions pour la production de protéines actives dépendantes de la vitamine k
EP1885388B1 (fr) 2005-05-10 2013-09-11 Biogen Idec MA Inc. Traitement et evaluation des troubles inflammatoires
WO2006138219A2 (fr) 2005-06-13 2006-12-28 Biogen Idec Ma Inc. Procedes d'evaluation de patients
US20090054307A1 (en) * 2005-09-01 2009-02-26 Howard Florey Institute Of Experimental Physiology And Medicine Prophylactic and therapeutic agents and uses therefor
GB0521488D0 (en) * 2005-10-21 2005-11-30 Ares Trading Sa Integral membrane protein
US7572618B2 (en) 2006-06-30 2009-08-11 Bristol-Myers Squibb Company Polynucleotides encoding novel PCSK9 variants
ES2636089T3 (es) 2006-10-27 2017-10-05 Genentech, Inc. Anticuerpos e inmunoconjugados y usos para los mismos
JP5588175B2 (ja) 2006-11-07 2014-09-10 メルク・シャープ・アンド・ドーム・コーポレーション Pcsk9のアンタゴニスト
US8093222B2 (en) 2006-11-27 2012-01-10 Isis Pharmaceuticals, Inc. Methods for treating hypercholesterolemia
CA2680832A1 (fr) * 2007-03-27 2008-10-02 Merck & Co., Inc. Procede de detection de pcsk9 secretee, autogeneree
JOP20080381B1 (ar) 2007-08-23 2023-03-28 Amgen Inc بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
JP5749492B2 (ja) 2007-10-26 2015-07-15 ダイナバックス テクノロジーズ コーポレイション 免疫応答と自己免疫を阻害する方法及び組成物
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CN102639150A (zh) 2009-10-30 2012-08-15 默沙东公司 Ax213和ax132 pcsk9拮抗剂和变体
BR112012032240A2 (pt) 2010-06-16 2019-09-24 Dynavax Technologies Corporation método de tratamento utilizando inibidores tlr7 e/ou tlr9
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WO2012088222A2 (fr) 2010-12-21 2012-06-28 The University Of North Carolina At Chapel Hill Procédés et compositions pour la production de protéines actives dépendantes de la vitamine k
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000004140A1 (fr) * 1998-07-15 2000-01-27 Human Genome Sciences, Inc. 71 proteines humaines secretees
WO2002026931A2 (fr) * 2000-09-25 2002-04-04 Human Genome Sciences, Inc. 71 proteines humaines secretees

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KR100236393B1 (ko) * 1996-02-02 1999-12-15 나까니시 히로유끼 사람성장호르몬을 함유하는 의약제제
US5858716A (en) * 1997-05-30 1999-01-12 Smithkline Beecham Corporation H2CAA71 polynucleotides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000004140A1 (fr) * 1998-07-15 2000-01-27 Human Genome Sciences, Inc. 71 proteines humaines secretees
WO2002026931A2 (fr) * 2000-09-25 2002-04-04 Human Genome Sciences, Inc. 71 proteines humaines secretees

Also Published As

Publication number Publication date
CA2441755A1 (fr) 2003-05-08
AU2002326293A1 (en) 2003-01-02
WO2002095010A3 (fr) 2004-02-12
AU2002320013A1 (en) 2002-11-18
EP1404702A2 (fr) 2004-04-07
WO2002095010A2 (fr) 2002-11-28
EP1414845A4 (fr) 2009-07-08
AU2002324424A1 (en) 2002-12-03
EP1414845A2 (fr) 2004-05-06
AU2002363296A1 (en) 2003-05-12
EP1381622A2 (fr) 2004-01-21
EP1379264A1 (fr) 2004-01-14
CA2441840A1 (fr) 2002-11-28
EP1379264A4 (fr) 2009-07-08
WO2003004622A2 (fr) 2003-01-16
CA2441417A1 (fr) 2002-11-14
CA2441832A1 (fr) 2002-12-27
WO2003038063A3 (fr) 2003-12-11
WO2002102993A3 (fr) 2004-03-25
CA2441702A1 (fr) 2002-12-27
EP1390390A2 (fr) 2004-02-25
EP1379132A2 (fr) 2004-01-14
WO2003038063A2 (fr) 2003-05-08
WO2002102994A2 (fr) 2002-12-27
EP1390390A4 (fr) 2009-07-08
WO2002102994A3 (fr) 2003-07-24
WO2002090526A2 (fr) 2002-11-14
AU2002354719A1 (en) 2003-01-21
CA2441397A1 (fr) 2002-10-03
EP1423134A2 (fr) 2004-06-02
EP1404702A4 (fr) 2009-07-08
WO2002076488A1 (fr) 2002-10-03
WO2003004622A3 (fr) 2004-02-19
AU2002332391A1 (en) 2003-01-02
CA2441416A1 (fr) 2003-01-16
WO2002102993A2 (fr) 2002-12-27
WO2002090526A3 (fr) 2003-10-30

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