EP1327674B1 - Utilisation d'un détergent concentré et procédé de nettoyage d'instruments chirurgicaux - Google Patents

Utilisation d'un détergent concentré et procédé de nettoyage d'instruments chirurgicaux Download PDF

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Publication number
EP1327674B1
EP1327674B1 EP02000728A EP02000728A EP1327674B1 EP 1327674 B1 EP1327674 B1 EP 1327674B1 EP 02000728 A EP02000728 A EP 02000728A EP 02000728 A EP02000728 A EP 02000728A EP 1327674 B1 EP1327674 B1 EP 1327674B1
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EP
European Patent Office
Prior art keywords
cleaning agent
acid
agent concentrate
cleaning
concentrate according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP02000728A
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German (de)
English (en)
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EP1327674A1 (fr
Inventor
Petra Tiarks
Jürgen Dr. Staffeldt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemische Fabrik Dr Weigert GmbH and Co
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Chemische Fabrik Dr Weigert GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemische Fabrik Dr Weigert GmbH and Co filed Critical Chemische Fabrik Dr Weigert GmbH and Co
Priority to EP02000728A priority Critical patent/EP1327674B1/fr
Priority to AT02000728T priority patent/ATE399199T1/de
Priority to PT02000728T priority patent/PT1327674E/pt
Priority to DE50212407T priority patent/DE50212407D1/de
Priority to ES02000728T priority patent/ES2307676T3/es
Publication of EP1327674A1 publication Critical patent/EP1327674A1/fr
Application granted granted Critical
Publication of EP1327674B1 publication Critical patent/EP1327674B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/26—Organic compounds containing nitrogen
    • C11D3/30—Amines; Substituted amines ; Quaternized amines
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/26—Organic compounds containing nitrogen
    • C11D3/33—Amino carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/32—Organic compounds containing nitrogen
    • C11D7/3218—Alkanolamines or alkanolimines
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/32—Organic compounds containing nitrogen
    • C11D7/3245—Aminoacids
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/32—Organic compounds containing nitrogen
    • C11D7/3254—Esters or carbonates thereof

Definitions

  • the invention relates to a use for cleaning and / or disinfecting medical instruments and / or apparatus as well as corresponding cleaning methods.
  • Surgical instruments as well as other medical devices are usually cleaned in the hospital using alkaline detergents and then disinfected chemically or thermally.
  • alkaline detergents can be aggressive to sensitive surfaces.
  • Surgical instruments contaminated with blood are often stored immediately after use, for example, in an aldehyde-containing disinfectant solution and initially remain there until they are cleared for cleaning in the dishwasher.
  • the blood is coagulated by the disinfectant and the protein components contained in the blood denatured by the aldehydic disinfectant.
  • Such particularly stubborn blood residues are often only to be removed by alkaline-active chlorine-containing cleaning agents.
  • the oxidizing Aktivchlorkomponente causes the decomposition of the denatured protein components.
  • Other constituents of disinfectants such as, for example, iodine can form residues that are difficult to remove.
  • the alkaline-active chlorine-containing cleaners have the disadvantages that they contain hazardous substances requiring labeling, that in their handling special precautions to protect the operator are required and that they represent an undesirable environmental impact in the wastewater.
  • EP-A-0 481 663 and EP-A-0 730 024 enzyme-containing detergents are known, which in particular can degrade blood proteins enzymatically.
  • EP-A-1 021 519 discloses an enzyme-free detergent concentrate for cleaning surgical instruments. As a disadvantage of the enzymatic cleanser is mentioned there that the enzyme activity can subside upon prolonged storage.
  • the invention has for its object to provide a use of a cleaning concentrate, which has a good cleaning effect against occurring in hospital mixed impurities such as coagulated blood and disinfectant residues and the build-up of residual impurities such as protein or limescale on the cleaned instruments and the dishwasher used itself counteracts.
  • the invention is based on the surprising finding that the combination of alkanolamine, complexing agent and enzyme results in a storage-stable cleaning agent concentrate which can remove dried, preheated or denatured blood residues of surgical instruments by automated cleaning, for example.
  • the iodine residues often originating from disinfectants or their reaction products with blood constituents are also removed.
  • a particular advantage of the invention is that the structure of protein and / or alkaline earth salt deposits or mixtures thereof is avoided on instruments and the interior of the dishwasher; Such deposits build up when using detergent concentrates
  • the prior art often after many rinse cycles on and can not or only with difficulty be removed.
  • the detergent concentrate surprisingly avoids such a deposit formation or removes existing deposits from cleaning processes of the prior art again.
  • the enzymes contained in the concentrate may in particular be amylases or proteases. Proteolytic enzymes are preferred. The amount of these proteolytic enzymes is preferably between 0.005 and 0.1 Anson units per g of concentrate.
  • the alkanolamine content according to the invention is preferably between 11 and 40 wt .-%, further 11 and 20 wt .-%, more preferably 11 and 15 wt .-%.
  • the alkanolamines used preferably have the structure: wherein R 1 represents a hydroxyalkyl group having 1 to 6 C atoms, and wherein R 2 and R 3 independently represent said hydroxyalkyl group or hydrogen.
  • the content of aminopolycarboxylic acid and / or its salts as complexing agent is preferably between 4 and 8 wt .-%, more preferably between 5 and 7 wt .-%.
  • the complexing agents serve to soften the water and can improve the cleaning action against lime soaps by complexing alkaline earth ions.
  • the concentrate may contain nitrilotriacetic acid and / or a salt of this acid, more preferably its trisodium salt.
  • this addition of NTA causes particularly good removal of lime soap even at low pH values in the range from 6 to 9.
  • the addition of NTA is also advantageous if the concentrate is to be prepared with a solution containing very mineral (hard) water to a ready-to-use solution.
  • the detergent concentrate has in ready to use dilute aqueous solution to a pH of 9 to 11, preferably 9.5 to 10.5.
  • Ready-to-use dilution means according to the invention a 0.5-100% strength aqueous solution of the cleaning agent concentrate. If pH values of a dilute solution of the cleaning agent concentrate are measured in the context of the present application, demineralized water (demineralized water) is used as the solvent. If the concentrate is made into a ready-to-use solution with ordinary tap water, slightly different pH values may result, depending on the nature of this water.
  • the adjustment of the pH to the stated range is preferably carried out by addition of acids and / or suitable buffer systems.
  • the addition of at least one organic acid is selected from the group consisting of mono-, di- or tricarboxylic acids having 2 to 6 carbon atoms.
  • these acids are preferably citric acid, tartaric acid, Malic acid, lactic acid, glycolic acid, glyoxylic acid, succinic acid, adipic acid and glutaric acid.
  • Citric acid is particularly preferred.
  • the acids are added to the concentrate preferably in an amount of 0.5 to 15% by weight, more preferably 2 to 10% by weight.
  • the corrosive effect of complexing agents such as NTA on anodized aluminum surfaces and the like can be reduced or completely avoided by adding at least one mono- and / or diester of phosphoric acid with aliphatic alcohols of chain length C 1 to C 22 and / or aliphatic diols and / or aliphatic polyols of chain length C 2 to C 22 .
  • This ester is commercially available under the name Hordaphos® MDGB. According to the invention, this gives a good cleaning effect even when using hard water and still a gentle action on exlox dressed aluminum surfaces.
  • preservatives may be added to the concentrate, for example p-hydroxybenzoic acid or its methyl ester, 5-bromo-5-nitro-1,3-dioxane, salicylic acid, 2-naphthyl-mN-dimethylthiocarbanilate, 5-chloro-5-methyl-4 -isothiazolin-3-one, 2-methyl-4-isothiazolin-3-one and mixtures of the latter two compounds.
  • a preferred preservative is p-hydroxybenzoic acid or its methyl ester. With the help of these preservatives microbial and fungal infestation of the detergent concentrate can be avoided.
  • conversion aids such as, for example, sodium cumene sulfonate, sodium toluene sulfonate, sodium xylene sulfonate, urea, glycols, in particular polypropylene glycols and polyethylene glycols, methylacetamide and fatty alcohols, such as cetyl alcohol.
  • wetting agents for example, the addition of N-acylglutamate as wetting agent is advantageous.
  • Conventional ionic, nonionic or amphoteric surfactants may also be added.
  • the machine cleaning takes place without human intervention during an automatic program sequence, in particular in a conventional instrument dishwasher.
  • cleaning and / or disinfection is intended to express that the concentrate can be used both in the combination of cleaning and disinfection in a single process step as well as in program sequences in which a cleaning step is followed by a separate disinfection step. In this case, the concentrate is usable in both of these steps.
  • the application of the aqueous solution of the cleaning agent concentrate is preferably done by spraying, but may, for example, be done by dipping or pouring.
  • the concentrate can be sprayed in a very high concentration, possibly pure, as a fine mist and initially act in this high concentration or pure. Subsequently, if necessary, additional water can be applied to the instruments to be cleaned and the so diluted cleaning solution is circulated and applied, for example. By spraying again on the instruments to be cleaned.
  • the action defined in step b) may, after application of the cleaning solution, be applied at rest, i. without continuous application or spraying or mechanical agitation or agitation of the cleaning solution.
  • highly concentrated cleaning solution can be sprayed on first, after spraying it is then allowed to act.
  • the exposure period may also include sections in which the cleaning solution is continuously re-applied to the instruments and / or mechanically circulated or moved in any other way. Also advantageous is a combination of these two types of action, ie first, in particular, a highly concentrated cleaner solution at rest and then diluting the cleaner with water under continuous circulation and re-spraying.
  • the aqueous solution of the cleaning concentrate is advantageously applied as 0.5 to 20%, preferably as 0.5 to 10%, more preferably as 1 to 5% aqueous solution.
  • the solution of the concentrate can be further diluted by additional water but should not fall below a minimum concentration of 0.5%. It should be noted that all percentages are by weight.
  • the exposure in step b) is preferably carried out at room temperature to 55 ° C, more preferably at 35 - 50 ° C, particularly preferably at 40 - 50 ° C.
  • Einwirktemperaturen of just over 40 ° C have been found to be particularly advantageous because on the one hand a good cleaning effect is achieved and on the other hand, the instruments to be cleaned are spared.
  • the exposure time in step b) is 2 s to 30 min, preferably 10 s to 10 min, more preferably 30 s to 5 min.
  • an additional disinfection step which, for example, can be carried out by chemical disinfectants, is preferred. Particularly preferred is the implementation of a thermal disinfection. This can be done as a downstream step, for example. With deionized water at 85 ° C to 95 ° C, preferably 93 ° C. This water can be used simultaneously for rinsing according to step c), so that rinsing and thermal disinfection are combined with each other in this way. However, instead of using fresh water, the thermodisinfection step can also be carried out with the cleaning solution of step b) heated to the corresponding temperature.
  • cycle belt washing machines it is also possible to carry out several cleaning steps in succession with the cleaning agent concentrate according to the invention. It is, for example, possible to use in a cleaning step an ultrasonic immersion bath which is filled with an aqueous solution of the cleaning agent concentrate according to the invention.
  • the invention achieves a good cleaning effect, especially in areas of surgical instruments that are difficult to access, for example in the area of the joints of scissors.
  • a detergent concentrate according to the invention is prepared on the basis of the information in the following table.
  • the amounts of the starting materials to be used are given in parts by weight.
  • Water (desalted) 65.0 pH of the concentrate 9.7 pH of a 1% aqueous solution (in deionized water) 9.9 1 Diester of phosphoric acid with butanol and ethylene glycol 2 complexing agents based on carboxylate / sulfonate-acrylic copolymers, Norso Haas SA, Verneuil, En Halatte, France
  • the instruments to be cleaned are first pre-rinsed with cold water for 2 minutes at room temperature. Subsequently, the dishwasher is filled with cold water and the detergent concentrate according to Example 1 in a concentration of 5 ml / l added. The cleaning solution is heated to 50 ° C and held for 5 minutes at this temperature. During this time, the cleaning solution is circulated by flushing the instruments.

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Detergent Compositions (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Claims (17)

  1. Utilisation d'un concentré d'agent nettoyant pour le nettoyage en machine et/ou la désinfection d'instruments et/ou appareils médicaux et/ou chirurgicaux, dans laquelle ledit concentré d'agent nettoyant contient :
    a) au moins 11% en poids d'au moins une alcanolamine,
    b) de 3 à 10% en poids d'au moins un acide aminopolycarboxylique et/ou d'un de ses sels comme agent complexant,
    c) au moins une enzyme,
    et dans laquelle le concentré d'agent nettoyant présente un pH dans la plage de 9 à 11 dans une solution aqueuse diluée prête à l'emploi.
  2. Utilisation du concentré d'agent nettoyant selon la revendication 1, caractérisée en ce que ledit concentré contient au moins une enzyme protéolytique.
  3. Utilisation du concentré d'agent nettoyant selon la revendication 1, caractérisée en ce que ledit concentré contient l'enzyme protéolytique en une quantité allant de 0,005 à 0,1 unité Anson par g de concentré.
  4. Utilisation du concentré d'agent nettoyant selon l'une des revendications 1 à 3, caractérisée en ce que la teneur en alcanolamine va de 11 à 40% en poids, de préférence de 11 à 20% en poids et de façon plus préférentielle de 11 à 15% en poids.
  5. Utilisation du concentré d'agent nettoyant selon l'une des revendications 1 à 3, caractérisée en ce que l'alcanolamine présente la structure suivante :
    Figure imgb0004
     où R1 représente un groupe hydroxyalkyle de 1 à 6 atomes de carbone et R2 et R3 représentent indépendamment l'un de l'autre le groupe hydroxyalkyle précité ou l'hydrogène.
  6. Utilisation du concentré d'agent nettoyant selon la revendication 5, caractérisée en ce que ledit concentré contient de la mono-, di- et/ou triéthanolamine.
  7. Utilisation du concentré d'agent nettoyant selon l'une des revendications 1 à 6, caractérisée en ce que la teneur en agent complexant va de 4 à 8% en poids, de préférence de 5 à 7% en poids.
  8. Utilisation du concentré d'agent nettoyant selon l'une des revendications 1 à 7, caractérisée en ce que ledit concentré contient de l'acide nitrilotriacétique et/ou des sels de l'acide nitrilotriacétique.
  9. Utilisation du concentré d'agent nettoyant selon l'une des revendications 1 à 8, caractérisée en ce que ledit concentré présente un pH dans la plage de 9,5 à 10,5 dans une solution aqueuse diluée prête à l'emploi.
  10. Utilisation du concentré d'agent nettoyant selon l'une des revendications 1 à 9, caractérisée en ce que ledit concentré contient en plus au moins un acide organique choisi dans le groupe constitué par des acides mono-, di- ou tricarboxyliques ayant de 2 à 6 atomes de carbone.
  11. Utilisation du concentré d'agent nettoyant selon la revendication 10, caractérisée en ce que ledit concentré contient au moins un acide choisi dans le groupe constitué par l'acide citrique, l'acide tartrique, l'acide malique, l'acide lactique, l'acide glycolique, l'acide glyoxalique, l'acide succinique, l'acide adipique et l'acide glutarique.
  12. Utilisation du concentré d'agent nettoyant selon l'une des revendications 1 à 11, caractérisée en ce que ledit concentré contient en plus au moins un mono- et/ou diester de l'acide phosphorique avec des alcools aliphatiques ayant une longueur de chaîne de C1 à C22 et/ou des diols aliphatiques et/ou des polyols aliphatiques ayant une longueur de chaîne de C2 à C22.
  13. Procédé de nettoyage en machine d'instruments et/ou appareils médicaux et/ou chirurgicaux, caractérisé en ce qu'il comprend les étapes consistant à :
    a) appliquer une solution aqueuse d'un concentré d'agent nettoyant selon l'une des revendications 1 à 12 diluée à une concentration allant de 0,5 à 10%,
    b) laisser agir la solution à une température allant de l'ambiante à la température d'ébullition de la solution,
    c) rincer.
  14. Procédé selon la revendication 13, caractérisé en ce que le concentré d'agent nettoyant est appliqué à l'étape a) sous la forme d'une solution aqueuse diluée à une concentration allant de 1 à 5%.
  15. Procédé selon la revendication 13 ou la revendication 14, caractérisé en ce que l'action de la solution à l'étape b) a lieu à une température allant de l'ambiante à 55°C, de préférence de 35 à 50°C et de façon plus préférentielle de 40 à 50°C.
  16. Procédé selon l'une des revendications 13 à 15, caractérisé en ce que le temps d'action à l'étape b) dure de 2 secondes à 30 minutes, de préférence de 10 secondes à 10 minutes et de façon plus préférentielle de 30 secondes à 5 minutes.
  17. Procédé selon l'une des revendications 13 à 16, caractérisée en ce qu'il comprend en plus une désinfection thermique.
EP02000728A 2002-01-11 2002-01-11 Utilisation d'un détergent concentré et procédé de nettoyage d'instruments chirurgicaux Expired - Lifetime EP1327674B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP02000728A EP1327674B1 (fr) 2002-01-11 2002-01-11 Utilisation d'un détergent concentré et procédé de nettoyage d'instruments chirurgicaux
AT02000728T ATE399199T1 (de) 2002-01-11 2002-01-11 Verwendung eines reinigungsmittelkonzentrats und verfahren zur reinigung chirurgischer instrumente
PT02000728T PT1327674E (pt) 2002-01-11 2002-01-11 Utilização de um detergente concentrado e processo de limpeza de instrumentos cirúrgicos
DE50212407T DE50212407D1 (de) 2002-01-11 2002-01-11 Verwendung eines Reinigungsmittelkonzentrats und Verfahren zur Reinigung chirurgischer Instrumente
ES02000728T ES2307676T3 (es) 2002-01-11 2002-01-11 Uso de un concentrado de producto de limpieza y procedimiento para la limpieza de instrumental quirurgico.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02000728A EP1327674B1 (fr) 2002-01-11 2002-01-11 Utilisation d'un détergent concentré et procédé de nettoyage d'instruments chirurgicaux

Publications (2)

Publication Number Publication Date
EP1327674A1 EP1327674A1 (fr) 2003-07-16
EP1327674B1 true EP1327674B1 (fr) 2008-06-25

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EP02000728A Expired - Lifetime EP1327674B1 (fr) 2002-01-11 2002-01-11 Utilisation d'un détergent concentré et procédé de nettoyage d'instruments chirurgicaux

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Country Link
EP (1) EP1327674B1 (fr)
AT (1) ATE399199T1 (fr)
DE (1) DE50212407D1 (fr)
ES (1) ES2307676T3 (fr)
PT (1) PT1327674E (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016127206A1 (fr) * 2015-02-12 2016-08-18 Whiteley Corporation Pty Ltd Détergent pour instruments médicaux

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2853632A1 (fr) * 2013-09-26 2015-04-01 Chemische Fabrik Dr. Weigert GmbH & Co. KG Kit et procédé de nettoyage et de désinfection d'instruments et d'appareils médicaux
DE102014213656A1 (de) 2014-07-14 2016-01-14 Chemische Fabrik Dr. Weigert Gmbh & Co. Kg Verfahren zum Reinigen chirurgischer Instrumente
US9693675B2 (en) * 2014-12-20 2017-07-04 Medivators Inc. Cleaning composition
JP7470255B2 (ja) * 2020-10-23 2024-04-17 ケミシェ・ファブリーク・ドクトル・ヴァイゲルト・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コンパニー・コマンディットゲゼルシャフト 液体洗浄剤濃縮物、レディ・トゥ・ユース溶液、その用途および洗浄方法

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CA2052649A1 (fr) * 1990-10-15 1992-04-16 Steris Inc. Methode combinee de nettoyage et de decontamination des instruments chirurgicaux en deux etapes
SI0730024T1 (en) * 1995-03-01 2000-02-29 Chemische Fabrik Dr. Weigert (Gmbh & Co.) Surgical instruments cleaning composition
US6235692B1 (en) * 1998-08-26 2001-05-22 Cottrell International, Llc Foaming enzyme spray cleaning composition and method of delivery
DE69920676D1 (de) * 1999-07-08 2004-11-04 Procter & Gamble Verfahren zur Herstellung von Amin-Umsetzungsprodukt-Teilchen
GB2360041B (en) * 2000-03-11 2003-01-22 Reckitt Benckiser Inc Storage stable concentrated cleaning solution

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016127206A1 (fr) * 2015-02-12 2016-08-18 Whiteley Corporation Pty Ltd Détergent pour instruments médicaux
CN107429204A (zh) * 2015-02-12 2017-12-01 怀特利集团控股有限公司 医疗器械洗涤剂
US10017719B2 (en) 2015-02-12 2018-07-10 Whiteley Corporation Pty. Ltd. Detergent for medical instrumentation
KR101920858B1 (ko) 2015-02-12 2018-11-22 위틀레이 코퍼레이션 프로프라이어테리 리미티트 의료 기기용 세제

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PT1327674E (pt) 2008-09-11
ES2307676T3 (es) 2008-12-01
DE50212407D1 (de) 2008-08-07
EP1327674A1 (fr) 2003-07-16
ATE399199T1 (de) 2008-07-15

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