EP1128832A4 - Composes, compositions et procedes pour traiter des infections virales et les maladies qui y sont liees - Google Patents
Composes, compositions et procedes pour traiter des infections virales et les maladies qui y sont lieesInfo
- Publication number
- EP1128832A4 EP1128832A4 EP99942288A EP99942288A EP1128832A4 EP 1128832 A4 EP1128832 A4 EP 1128832A4 EP 99942288 A EP99942288 A EP 99942288A EP 99942288 A EP99942288 A EP 99942288A EP 1128832 A4 EP1128832 A4 EP 1128832A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- treating
- compounds
- methods
- viral infections
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9747698P | 1998-08-21 | 1998-08-21 | |
| US97476P | 1998-08-21 | ||
| US11321298P | 1998-12-22 | 1998-12-22 | |
| US113212P | 1998-12-22 | ||
| US11932899P | 1999-02-09 | 1999-02-09 | |
| US119328P | 1999-02-09 | ||
| US13558599P | 1999-05-24 | 1999-05-24 | |
| US13558699P | 1999-05-24 | 1999-05-24 | |
| US135586P | 1999-05-24 | ||
| US135585P | 1999-05-24 | ||
| PCT/US1999/018785 WO2000010573A1 (fr) | 1998-08-21 | 1999-08-19 | Composes, compositions et procedes pour traiter des infections virales et les maladies qui y sont liees |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP1128832A1 EP1128832A1 (fr) | 2001-09-05 |
| EP1128832A4 true EP1128832A4 (fr) | 2003-03-05 |
Family
ID=27536838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP99942288A Withdrawn EP1128832A4 (fr) | 1998-08-21 | 1999-08-19 | Composes, compositions et procedes pour traiter des infections virales et les maladies qui y sont liees |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1128832A4 (fr) |
| JP (1) | JP2002523371A (fr) |
| KR (1) | KR20010099623A (fr) |
| CN (1) | CN1325309A (fr) |
| AU (1) | AU743411B2 (fr) |
| BR (1) | BR9913157A (fr) |
| CA (1) | CA2341970A1 (fr) |
| ID (1) | ID27787A (fr) |
| IL (1) | IL141456A0 (fr) |
| WO (1) | WO2000010573A1 (fr) |
Families Citing this family (79)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0011441A (pt) * | 1999-06-10 | 2002-07-16 | Warner Lambert Co | Derivados de rodanina para uso em um método de inibição da agregação da proteìna amilóide e formação de imagens de depósitos amilóides |
| JP2003531104A (ja) | 1999-08-31 | 2003-10-21 | マキシア・ファーマシューティカルズ・インコーポレイテッド | ベンジリデン−チアゾリジンジオン類およびアナログ類ならびに炎症の治療におけるその使用 |
| US6727267B2 (en) | 2000-04-05 | 2004-04-27 | Tularik Inc. | NS5B HVC polymerase inhibitors |
| US6448281B1 (en) | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
| JP5260818B2 (ja) * | 2000-09-29 | 2013-08-14 | ノバルティス・インターナショナル・ファーマシューティカル・リミテッド | 高親和性低分子Ｃ５ａ受容体調節物質 |
| BR0207846A (pt) | 2001-03-07 | 2005-09-13 | Incyte San Diego Inc | Derivados heterocìclicos para o tratamento de câncer e outras doenças proliferativas |
| US7265139B2 (en) | 2001-03-08 | 2007-09-04 | Incyte San Diego Inc. | RXR activating molecules |
| GB2376944A (en) * | 2001-05-18 | 2002-12-31 | Pantherix Ltd | Polycyclic heterocyclic compounds and their therapeutic use |
| JP4558314B2 (ja) | 2001-07-20 | 2010-10-06 | ベーリンガー インゲルハイム （カナダ） リミテッド | ウイルスポリメラーゼインヒビター |
| EP2335700A1 (fr) | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Inhibiteurs de la polymerase du virus hepatitis C avec une structure heterobicylic |
| WO2003026587A2 (fr) | 2001-09-26 | 2003-04-03 | Bristol-Myers Squibb Company | Composes pour traiter le virus de l'hepatite c |
| WO2003043998A1 (fr) * | 2001-11-15 | 2003-05-30 | Incyte San Diego Incorporated | Heterocycles n-substitues pour le traitement de l'hypercholesterolemie, de la dyslipidemie et autres troubles du metabolisme, du cancer et de pathologies diverses |
| US7196108B2 (en) | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
| US7102000B2 (en) | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
| GB2387172A (en) * | 2002-03-28 | 2003-10-08 | Pantherix Ltd | [(Aryl-/arylthio-)aryl]methylene substituted azole & azine derivatives and their therapeutic use as antibacterials |
| US20060281798A1 (en) * | 2002-05-17 | 2006-12-14 | Qlt Inc. | Methods of using thiazolidinedithione derivatives |
| JP4271148B2 (ja) | 2002-05-20 | 2009-06-03 | ブリストル−マイヤーズ スクイブ カンパニー | 置換シクロアルキルｐ１’ｃ型肝炎ウイルスインヒビター |
| ES2350201T3 (es) | 2002-05-20 | 2011-01-20 | Bristol-Myers Squibb Company | Sulfamidas heterocíclicas como inhibidores del virus de la hepatitis c. |
| ATE503764T1 (de) | 2002-05-20 | 2011-04-15 | Bristol Myers Squibb Co | Inhibitoren des hepatitis-c-virus |
| MY140680A (en) | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
| MXPA05000256A (es) | 2002-07-01 | 2005-07-15 | Upjohn Co | Inhibidores de polimerasa ns5b del vhc. |
| BR0305426A (pt) | 2002-07-01 | 2004-08-24 | Upjohn Co | Compostos inibidores de ns5b polimerase de hcv, bem como composição farmacêutica compreendendo os mesmos |
| FR2845000B1 (fr) * | 2002-09-27 | 2005-05-27 | Oreal | Utilisation d'un compose heterocyclique ou de l'un de ses sels pour stimuler ou induire la pousse des cheveux et/ou freiner leur chute |
| US7235573B2 (en) | 2002-09-30 | 2007-06-26 | The Regents Of The University Of California | Methods of treating secretory diarrhea using cystic fibrosis transmembrane conductance regulator protein inhibitors |
| AU2003277162C1 (en) * | 2002-09-30 | 2009-12-24 | The Regents Of The University Of California | Cystic fibrosis transmembrane conductance regulator protein inhibitors and uses thereof |
| US20060276520A1 (en) * | 2002-11-13 | 2006-12-07 | Rigel Pharmaceuticals, Inc. | Rhodanine derivatives and pharmaceutical compositions containing them |
| ATE422895T1 (de) | 2003-04-16 | 2009-03-15 | Bristol Myers Squibb Co | Makrocyclische isochinolinpeptidinhibitoren des hepatitis-c-virus |
| WO2005007141A2 (fr) * | 2003-07-11 | 2005-01-27 | Proteologics, Inc. | Inhibiteurs de l'ubiquitine ligase et methodes associees |
| FR2858324A1 (fr) * | 2003-07-30 | 2005-02-04 | Centre Nat Rech Scient | Nouveaux composes antibiotiques, compositions pharmaceutiques les contenant et leurs utilisations |
| US7112601B2 (en) | 2003-09-11 | 2006-09-26 | Bristol-Myers Squibb Company | Cycloalkyl heterocycles for treating hepatitis C virus |
| WO2005041951A2 (fr) * | 2003-10-28 | 2005-05-12 | Rigel Pharmaceuticals, Inc. | Compositions de rhodanine utilisables comme agents antiviraux |
| US7026339B2 (en) | 2003-11-07 | 2006-04-11 | Fan Yang | Inhibitors of HCV NS5B polymerase |
| US7132504B2 (en) | 2003-11-12 | 2006-11-07 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7309708B2 (en) | 2003-11-20 | 2007-12-18 | Birstol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US7135462B2 (en) | 2003-11-20 | 2006-11-14 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| DK1718608T3 (da) | 2004-02-20 | 2013-10-14 | Boehringer Ingelheim Int | Virale polymeraseinhibitorer |
| EP2206715A1 (fr) | 2004-02-24 | 2010-07-14 | Japan Tobacco, Inc. | Composé héterotétracycliques fusionnés et leur utilisation en tant qu'inhibiteurs de la polymérase du HCV |
| US20070049593A1 (en) | 2004-02-24 | 2007-03-01 | Japan Tobacco Inc. | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor |
| US7659263B2 (en) | 2004-11-12 | 2010-02-09 | Japan Tobacco Inc. | Thienopyrrole compound and use thereof as HCV polymerase inhibitor |
| KR20070116682A (ko) | 2005-05-04 | 2007-12-10 | 에프. 호프만-라 로슈 아게 | 헤테로사이클릭 항바이러스성 화합물 |
| CA2608821A1 (fr) * | 2005-06-15 | 2006-12-28 | Shibo Jiang | Compositions antivirales comprenant des phenyl-furanes heterocycliques substitues et composes associes |
| US8017612B2 (en) | 2006-04-18 | 2011-09-13 | Japan Tobacco Inc. | Piperazine compound and use thereof as a HCV polymerase inhibitor |
| CN101437824B (zh) * | 2006-05-04 | 2013-03-13 | 肝炎与病毒研究所 | 用于慢性肝炎病毒治疗的乙型肝炎病毒抗原分泌的抑制剂 |
| JP2010505902A (ja) | 2006-10-10 | 2010-02-25 | メディヴィル・アクチエボラーグ | Ｈｃｖヌクレオシド阻害剤 |
| WO2008082537A2 (fr) | 2006-12-19 | 2008-07-10 | The General Hospital Corporation | Composés pour moduler l'intégrine cd11b/cd18 |
| AP2009005073A0 (en) | 2007-06-29 | 2009-12-31 | Gilead Sciences Inc | Antiviral compounds |
| MX2009013827A (es) | 2007-06-29 | 2010-03-01 | Gilead Sciences Inc | Compuestos antivirales. |
| WO2009059243A1 (fr) * | 2007-11-01 | 2009-05-07 | The Uab Research Foundation | Traitement et prévention d'infections virales |
| EP2234608A2 (fr) | 2007-12-11 | 2010-10-06 | Viamet Pharmaceuticals, Inc. | Inhibiteurs de métalloenzymes utilisant des fractions de liaison à un métal en combinaison avec des fractions de ciblage |
| US7947717B2 (en) | 2008-07-18 | 2011-05-24 | Burnham Institute For Medical Research | Inhibitors of lethal factor protease |
| NZ593806A (en) | 2008-12-03 | 2014-04-30 | Presidio Pharmaceuticals Inc | Inhibitors of hcv ns5a |
| CN104163816A (zh) | 2008-12-03 | 2014-11-26 | 普雷西迪奥制药公司 | Hcv ns5a的抑制剂 |
| BRPI1012282A2 (pt) | 2009-03-27 | 2015-09-22 | Presidio Pharmaceuticals Inc | inibidores de anel fundidos da hepatite c. |
| WO2011058084A1 (fr) | 2009-11-14 | 2011-05-19 | F. Hoffmann-La Roche Ag | Marqueurs biologiques destinés à prédire une réaction rapide au traitement du virus de l'hépatite c (hcv) |
| KR20120085877A (ko) | 2009-12-02 | 2012-08-01 | 에프. 호프만-라 로슈 아게 | Ｈｃｖ 치료에 대한 지속된 반응을 예측하기 위한 생체마커 |
| WO2011075784A1 (fr) * | 2009-12-23 | 2011-06-30 | Peter Maccallum Cancer Institute | Composés, leurs préparations et leurs utilisations |
| EP2575866A4 (fr) | 2010-05-24 | 2013-10-16 | Presidio Pharmaceuticals Inc | Inhibiteurs de ns5a du vhc |
| KR101159000B1 (ko) * | 2010-06-18 | 2012-06-21 | (주) 에빅스젠 | 신규한 로다닌 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 ａｉｄｓ 예방 또는 치료용 약학 조성물 |
| US9023876B2 (en) | 2010-07-08 | 2015-05-05 | Adhaere Pharmaceuticals, Inc. | Compounds and methods for regulating integrins |
| US9255088B2 (en) | 2010-08-11 | 2016-02-09 | The Regents Of The University Of California | Premature-termination-codons readthrough compounds |
| WO2012123298A1 (fr) | 2011-03-11 | 2012-09-20 | F. Hoffmann-La Roche Ag | Composés antiviraux |
| WO2012175581A1 (fr) | 2011-06-24 | 2012-12-27 | F. Hoffmann-La Roche Ag | Composés antiviraux |
| JP5808496B2 (ja) | 2011-10-10 | 2015-11-10 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 抗ウイルス化合物 |
| ES2564906T3 (es) | 2011-12-16 | 2016-03-29 | F. Hoffmann-La Roche Ag | Inhibidores de NS5A del VHC |
| LT2794628T (lt) | 2011-12-20 | 2017-07-10 | Riboscience Llc | 4`-azido-3`-fluoro pakeistieji nukleozido dariniai kaip hcv replikacijos inhibitoriai |
| SI2794629T1 (sl) | 2011-12-20 | 2017-10-30 | Riboscience Llc | 2'4'-difluoro-2'-metil substituirani nukleozidni derivati k0t zaviralci replikacije hcv-rna |
| MX2014009799A (es) | 2012-02-24 | 2014-09-08 | Hoffmann La Roche | Compuestos antivirales. |
| EP2828249B1 (fr) | 2012-03-23 | 2018-10-10 | The Regents of The University of California | Composés de translecture de codons de terminaison prématurés |
| CA2882853C (fr) | 2012-04-20 | 2021-11-23 | Vineet Gupta | Composes et methodes pour la regulation d'integrines |
| US20140010783A1 (en) | 2012-07-06 | 2014-01-09 | Hoffmann-La Roche Inc. | Antiviral compounds |
| CA2892589A1 (fr) | 2013-01-23 | 2014-07-31 | F. Hoffmann-La Roche Ag | Derives de triazole antiviraux |
| WO2014135422A1 (fr) | 2013-03-05 | 2014-09-12 | F. Hoffmann-La Roche Ag | Composés antiviraux |
| RU2534613C2 (ru) | 2013-03-22 | 2014-11-27 | Александр Васильевич Иващенко | Алкил 2-{ [(2r,3s,5r)-5-(4-амино-2-оксо-2н-пиримидин-1-ил)- -гидрокси-тетрагидро-фуран-2-илметокси]-фенокси-фосфориламино} -пропионаты, нуклеозидные ингибиторы рнк-полимеразы hcv ns5b, способы их получения и применения |
| US20180200280A1 (en) | 2013-05-16 | 2018-07-19 | Riboscience Llc | 4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication |
| MY186547A (en) | 2013-05-16 | 2021-07-26 | Riboscience Llc | 4?-fluoro-2?-methyl substituted nucleoside derivatives |
| EA201592185A1 (ru) | 2013-05-16 | 2016-05-31 | Рибосайенс Ллк | 4'-азидо, 3'-дезокси-3'-фторзамещенные нуклеозидные производные |
| JP7299897B2 (ja) | 2017-09-21 | 2023-06-28 | リボサイエンス リミティド ライアビリティ カンパニー | Ｈｃｖのｒｎａ複製阻害剤としての４’－フルオロ－２’－メチル置換ヌクレオシド誘導体 |
| KR101893988B1 (ko) | 2018-05-16 | 2018-08-31 | (주)에빅스젠 | 로다닌 유도체를 함유하는 aids 예방 또는 치료용 약학 조성물 |
| TW202348228A (zh) | 2022-02-24 | 2023-12-16 | 德商艾斯巴赫生物有限公司 | 病毒組合療法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993021934A1 (fr) * | 1992-05-01 | 1993-11-11 | Commonwealth Scientific And Industrial Research Organisation | Heteropolytungstates utilises dans le traitement des infections a flavivirus |
| WO1998020013A1 (fr) * | 1996-11-07 | 1998-05-14 | Andreas Johannes Kesel | Nouveaux produits de condensation de knoevenagel, leur procede de production et leur utilisation |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909467A (en) * | 1958-07-09 | 1959-10-20 | Us Vitamin Pharm Corp | 3-(d-alpha-methylphenethyl)-5-methyl-1, 3-oxazolidine-2, 4-dione |
| US3888984A (en) * | 1972-03-13 | 1975-06-10 | Lilly Industries Ltd | Oxazole and imidazole derivatives as antifungal agents |
| AU6610081A (en) * | 1980-01-24 | 1981-07-30 | Senju Pharmaceutical Co., Ltd. | Thiazolidine derivatives |
| US4367234A (en) * | 1980-07-28 | 1983-01-04 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
| CA2153553A1 (fr) * | 1994-07-13 | 1996-01-14 | Hidekazu Suzuki | Emulsion stable de lipides |
| US5834466A (en) * | 1994-12-22 | 1998-11-10 | The Regents Of The University Of California | Method for protecting of heart by limiting metabolic and ionic abnormalities developed during ischemia, following ischemia or resulting from ischemia |
-
1999
- 1999-08-19 CN CN99812282A patent/CN1325309A/zh active Pending
- 1999-08-19 BR BR9913157-9A patent/BR9913157A/pt not_active Application Discontinuation
- 1999-08-19 IL IL14145699A patent/IL141456A0/xx unknown
- 1999-08-19 EP EP99942288A patent/EP1128832A4/fr not_active Withdrawn
- 1999-08-19 KR KR1020017002117A patent/KR20010099623A/ko not_active Application Discontinuation
- 1999-08-19 CA CA002341970A patent/CA2341970A1/fr not_active Abandoned
- 1999-08-19 AU AU55702/99A patent/AU743411B2/en not_active Ceased
- 1999-08-19 JP JP2000565894A patent/JP2002523371A/ja active Pending
- 1999-08-19 ID IDW20010428A patent/ID27787A/id unknown
- 1999-08-19 WO PCT/US1999/018785 patent/WO2000010573A1/fr not_active Application Discontinuation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993021934A1 (fr) * | 1992-05-01 | 1993-11-11 | Commonwealth Scientific And Industrial Research Organisation | Heteropolytungstates utilises dans le traitement des infections a flavivirus |
| WO1998020013A1 (fr) * | 1996-11-07 | 1998-05-14 | Andreas Johannes Kesel | Nouveaux produits de condensation de knoevenagel, leur procede de production et leur utilisation |
Non-Patent Citations (1)
| Title |
|---|
| See also references of WO0010573A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| IL141456A0 (en) | 2002-03-10 |
| CN1325309A (zh) | 2001-12-05 |
| WO2000010573A1 (fr) | 2000-03-02 |
| EP1128832A1 (fr) | 2001-09-05 |
| KR20010099623A (ko) | 2001-11-09 |
| CA2341970A1 (fr) | 2000-03-02 |
| AU5570299A (en) | 2000-03-14 |
| ID27787A (id) | 2001-04-26 |
| BR9913157A (pt) | 2001-05-15 |
| AU743411B2 (en) | 2002-01-24 |
| JP2002523371A (ja) | 2002-07-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1128832A4 (fr) | Composes, compositions et procedes pour traiter des infections virales et les maladies qui y sont liees | |
| EP1109580A4 (fr) | Methodes de traitement ou de prevention des infections virales et des maladies associees | |
| EP1115286A4 (fr) | Procedes de traitement ou de prevention d'infections virales et de maladies associees | |
| AU1099000A (en) | Novel compounds and compositions for treating hepatitis c infections | |
| HK1023371A1 (en) | Compositions and methods for treating viral infections | |
| IL139002A0 (en) | Compositions for the treatment of hiv and other viral infections | |
| AP2000002010A0 (en) | Novel pharmaceutical compositions for treating and saving and the methods for the preparation thereof | |
| EP1109548A4 (fr) | Utilisation de procedes et de compositions a base de tocotrienols pour traiter et prevenir les maladies osseuses | |
| EP1051169A4 (fr) | Composes, compositions et methodes de traitement ou de prevention d'infections pneumovirales et de maladies associees | |
| ZA200003768B (en) | Methods and compositions for treating diseases and conditions of the eye. | |
| EP0920419A4 (fr) | Composes, compositions et procedes de traitement de la grippe | |
| AU7165498A (en) | Methods for treating viral infections | |
| AU2002324753A1 (en) | Composition and method for treating viral infection | |
| ZA200203435B (en) | Method and compositions for treating pulmonary diseases. | |
| EP1135137A4 (fr) | Compositions polymeres servant a traiter des infections virales | |
| IL133760A0 (en) | Composition for the treatment of dandruff | |
| IL128351A0 (en) | Pharmaceutical composition for treating viral diseases | |
| AU2003237088A8 (en) | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | |
| MXPA03005526A (es) | Antagonistas ccr5 y polipeptido dp-178 para el tratamiento de infecciones virales. | |
| IL140417A0 (en) | NOVEL COMPOUNDS DERIVED FROM β-D-XYLOSE, PREPARATION METHOD AND THERAPEUTIC USE | |
| AU6798000A (en) | Compounds, compositions and methods for treating influenza | |
| AU3698199A (en) | Radioimmuno-pharmacon for treating the hiv-1 infection | |
| ZA200004856B (en) | Treatment of panic attacks. | |
| HUP9900123A3 (en) | 1-isothiazolidinone derivatives of azetidine-2-one, processes for the preparation thereof and use thereof | |
| EP1027352A4 (fr) | Composes antibacteriens de la classe des carbapenemes, compositions et procedes de traitement |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20010315 |
|
| AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
| AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
| A4 | Supplementary search report drawn up and despatched |
Effective date: 20030122 |
|
| 17Q | First examination report despatched |
Effective date: 20040226 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20040908 |