EP0629101A1 - Prothèse auditive à porter dans l'oreille et procédé pour sa fabrication - Google Patents

Prothèse auditive à porter dans l'oreille et procédé pour sa fabrication Download PDF

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Publication number
EP0629101A1
EP0629101A1 EP94810287A EP94810287A EP0629101A1 EP 0629101 A1 EP0629101 A1 EP 0629101A1 EP 94810287 A EP94810287 A EP 94810287A EP 94810287 A EP94810287 A EP 94810287A EP 0629101 A1 EP0629101 A1 EP 0629101A1
Authority
EP
European Patent Office
Prior art keywords
hearing aid
membrane
aid according
skeleton
ear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP94810287A
Other languages
German (de)
English (en)
Other versions
EP0629101B1 (fr
Inventor
Walter Aebi
Elmar Mock
Grégoire Iten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bernafon AG
Original Assignee
Ascom Audiosys AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ascom Audiosys AG filed Critical Ascom Audiosys AG
Publication of EP0629101A1 publication Critical patent/EP0629101A1/fr
Application granted granted Critical
Publication of EP0629101B1 publication Critical patent/EP0629101B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04R—LOUDSPEAKERS, MICROPHONES, GRAMOPHONE PICK-UPS OR LIKE ACOUSTIC ELECTROMECHANICAL TRANSDUCERS; DEAF-AID SETS; PUBLIC ADDRESS SYSTEMS
    • H04R25/00—Deaf-aid sets, i.e. electro-acoustic or electro-mechanical hearing aids; Electric tinnitus maskers providing an auditory perception
    • H04R25/65—Housing parts, e.g. shells, tips or moulds, or their manufacture
    • H04R25/652—Ear tips; Ear moulds
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04R—LOUDSPEAKERS, MICROPHONES, GRAMOPHONE PICK-UPS OR LIKE ACOUSTIC ELECTROMECHANICAL TRANSDUCERS; DEAF-AID SETS; PUBLIC ADDRESS SYSTEMS
    • H04R25/00—Deaf-aid sets, i.e. electro-acoustic or electro-mechanical hearing aids; Electric tinnitus maskers providing an auditory perception
    • H04R25/65—Housing parts, e.g. shells, tips or moulds, or their manufacture
    • H04R25/658—Manufacture of housing parts
    • H04R25/659—Post-processing of hybrid ear moulds for customisation, e.g. in-situ curing

Definitions

  • the invention relates to a hearing aid to be worn in the ear and a method for its production in accordance with the preambles of the corresponding independent claims.
  • the well-known hearing aids to be worn in the ear meet the requirements mentioned to a varying degree. Some of these are briefly described below and compared with the list of requirements above.
  • the most frequently used method for the production of hearing aids to be worn in the ear is that a hearing aid consultant, who at the same time examines the hearing impairments of the potential user, produces a silicone cast of the ear canal, so that a transparent, positive model of the ear canal is created after this silicone cast and that in this model a plastic polymerizing with the help of light is poured, which hardens from the outside in to a certain layer thickness.
  • a hollow molded body is formed in which the electronic components of the hearing aid are installed, with at least one opening for the loudspeaker and for a pressure equalization channel being arranged against the inside of the ear.
  • the molded body Towards the exit of the auditory canal, the molded body is closed with a cover, which in turn contains an opening for the pressure compensation channel and a separate compartment for a replaceable battery.
  • the hearing aid produced in this way has a molded body with a very good fit, but this covers the skin of the auditory canal to such an extent that there can be no question of ventilation. This inevitably leads to increased excretion of sweat and cerumen.
  • the part of the ear canal that remains free between the eardrum and the hearing aid is open to the outside through the pressure equalization channel, so that pressure equalization can take place and moisture can also escape.
  • the pressure equalization channel can in turn increase the feedback between loudspeaker and microphone.
  • a further disadvantage of this hearing aid is that the openings to the loudspeaker and pressure equalization channel can easily become clogged with cerumen, although these can be covered with a liquid-impermeable but gas-permeable membrane, as proposed according to European patent application No. 0310866 (published April 12, 1989) becomes.
  • the described method for producing the hearing aid is complex because the molded body has to be cast in several positive-negative steps and because these production steps are such that they cannot be carried out by the hearing aid consultant himself. In other words, the manufacturer of the hearing aids must deal with the individual completion of individual, user-specific devices.
  • the object of the invention to provide a hearing aid to be worn in the ear with a shaped body adapted to an individual ear canal, the hearing aid on the one hand having improvements in terms of wearing comfort compared to known hearing aids of this type and on the other hand being manufactured in a simpler process, in particular individualized can be. Furthermore, a method is to be specified according to which the hearing aid is manufactured, in particular individualized.
  • a general hearing aid (not yet adapted to an individual auditory canal) is produced as standard.
  • This has an advantageously plastically deformable skeleton which carries the electronic components of the hearing aid and to which a flexible membrane is attached in such a way that a skeleton and membrane form a casting space which has an open casting channel towards the outside.
  • the hearing aid is now individualized (adapted to an individual ear canal) by deforming the skeleton according to the individual shape of the ear canal, by positioning the hearing aid, which has already been partially customized in this way, in the ear and then pouring the casting space with a hardening plastic mass, the membrane deforming and the resulting molded body is shaped according to the ear canal.
  • the skeleton and membrane are designed and attached to each other in such a way that no reworking of the hearing aid individualized by skeletal deformation and casting of the molded body is necessary.
  • the material and structure of the membrane are such that they are permeable to gases due to their extremely fine porosity and corresponding surface quality, but are impermeable to liquids and that they are sufficiently elastic to be able to fit the ear canal wall as wrinkle-free as possible .
  • the membrane is not only gas-permeable perpendicular to its surfaces, but also parallel to it, such that not only can the air displaced during casting escape through this membrane, but that it can also serve as a pressure compensation means and for ventilation of the ear canal skin. This property can be further increased if the membrane has on its side facing the skeleton a coarse porous intermediate layer, which can be a layer of an open-cell foam or a mesh. So that the membrane can continue to function for a long time, it is also water and oil repellent.
  • a foamed and stretched PTFE membrane which is sold under the name GORE-TEX® by W.L. Gore & Co GmbH (D-88011 Putzbrunn near Munich) is manufactured, has the required properties and is suitable for the application. It is a foamed and stretched PTFE material (polytetrafluoroethane) that forms a very porous membrane. This membrane not only has the requested physical properties, but is also very kind to the skin and body (it can also be used as a provisional skin for large wounds).
  • Woven, knitted or knitted materials made of plastic fibers are conceivable as further membrane materials, which are coated with an oil and water-repellent layer at least on the surface facing the ear canal.
  • This layer can be, for example, an evaporated layer of Parylen® (Union Carbide Corp., USA) or silane.
  • Figure 1 shows the principle of the hearing aid according to the invention in a very schematic manner.
  • the hearing aid is shown cut in its already individualized state and parallel to the axis of the auditory canal. It essentially has the shape of an irregular truncated cone with a lateral surface M, a larger end face AS facing in the auditory canal and a smaller end face IS facing inward in the auditory canal.
  • the hearing aid essentially consists of a shaped body 1, the shape of which is adapted to the auditory canal and at least on the lateral surface M, that is, where it touches the auditory canal wall when the device is being worn, as already described, is covered with a membrane 2.
  • the hearing aid also has a skeleton, which essentially consists of three parts: an outer support element 3, which essentially forms the outer end face AS of the device, an inner support element 4, which essentially forms the inner end face of the device, and a connecting element 5, that connects the two support elements 3 and 4 together.
  • the connecting element 5 serves to hold the two support elements 3 and 4 in a mutual position before the casting of the molded body, which roughly corresponds to an auditory canal.
  • the connecting element 5 is advantageously deformable to a limited extent, so that the mutual position of the support elements 3 and 4 can be adapted to the individual auditory canal as a first individualization step.
  • the outer support element 3 carries a microphone 31, for which it is provided with sound passage openings 32 at the corresponding point. Furthermore, the outer support element 3 forms a closable battery compartment 33 and carries a pouring or injection opening 34.
  • the inner support element 4 carries a loudspeaker 41 and is also provided with sound passage openings 42.
  • the membrane 2 which surrounds the molded body at least on its lateral surface M, is attached to the two support elements around the two end faces AS and IS (positions X in the figure).
  • the membrane 2 can also completely span the inner end face IS. It can also partially span the outer end face, but must leave the pouring or injection opening 34 and the battery compartment 33 freely accessible.
  • the amplifier electronics can either be carried by one of the support elements or by the connecting element. It can also be cast into the molded body without special attachment to the skeleton.
  • the skeleton is advantageously made of plastic.
  • the membrane can be attached to the support elements, for example by welding, by gluing or by appropriate tensioning elements. Further fastening options are described in connection with FIGS. 2 to 4.
  • the general hearing aid from which the individualized hearing aid shown schematically in FIG. 1 is produced differs from this in that the molded body 1 is only present as an undetermined casting cavity between the support elements and the membrane.
  • the membrane 2 fastened to the support elements 3 and 4 thus loosely surrounds the skeleton and, together with the support elements, forms a casting space which surrounds the skeleton in a substantially tubular manner and which opens out to the outside through the pouring channel 34.
  • the casting space between the membrane and the skeleton is poured out through the casting channel 34 with a suitable plastic, while the hearing aid is positioned in the auditory canal.
  • the plastic hardens to an individualized molded body 1.
  • the requirements for the plastic are that it can be easily poured in through the pouring channel and that it hardens quickly. Of course, it must be skin-friendly.
  • the casting compound made by 3M under the name Imprint® and mainly used in dental technology based on vinyl polysiloxane is very suitable for the present application.
  • This two-component casting compound is available in easy-to-use twin cartridges with mixing tips, which can be placed directly on the pouring channel 34.
  • casting compounds can also be used. Such materials are advantageously used that do not split off any low molecular weight residues during the polymerization.
  • Additives for example small foam bodies or hollow glass spheres, can be added to the casting composition to improve the properties of the molded body as a sound and vibration damper.
  • the steps required to individualize the general hearing aid are deforming the skeleton and casting the molded body. Both steps can be carried out by the hearing aid consultant without any problems, such that the user can take the hearing aid with him after a session and that the manufacturer only has to process general hearing aids.
  • FIGS. 2 to 4 differ from one another essentially in that the electronic components are accessible to different extents.
  • the principle described in connection with FIG. 1 has been retained in all embodiments.
  • FIG. 2 shows a first exemplary embodiment of the hearing aid according to the invention, again in section parallel to the auditory canal axis.
  • the device is positioned in an auditory canal, the auditory canal walls being indicated by the lines G.
  • the hearing aid shown is already individualized. It has a skeleton, which in turn consists of an outer support element 3, an inner support element 4 and a connecting element 5 and which carries the electronic components.
  • This skeleton is arranged in a cast molded body 1, the surface of which facing the auditory canal is covered by a sack-shaped membrane 2.
  • the two support elements 3 and 4 are designed as an inner capsule 4.1 with an inner closing element 4.2 and an outer capsule 3.1 with an outer closing element 3.2, through which an at least partial accessibility of the electronic components on the individualized hearing aid.
  • the loudspeaker 41 is accommodated in the inner capsule 4.1 and is inserted through its opening before the closing element 4.2 is placed on it.
  • the microphone 31 is advantageously accommodated in correspondingly arranged compartments in a microphone compartment 31.1 and a battery in a battery compartment 33.
  • the amplifier electronics 6 can also be accommodated in the outer capsule 3.1.
  • the electrical connections between the electronic components of the hearing aid run, for example, through the deformable connecting element 5.
  • the pouring channel 34 is also arranged, for example molded onto the outer capsule 3.1.
  • the openings of the individual compartments of the outer capsule 3.1 and the opening of the pouring channel 34 advantageously lie essentially in one plane, so that they can be closed together by the closing element 3.2.
  • separate closing elements can also be provided for the different openings or partial areas of the common closing element 3.2 can be designed for individual of the openings in such a way that they can be opened and closed without the entire closing element 3.2 having to be opened.
  • the battery compartment 33 is closed with such a partial closing element 33.1 and is therefore very easily accessible to the user.
  • the sack-shaped membrane 2 has a main opening, the edge of which is fastened around the region in which the opening of the outer capsule 3.1 and the opening of the pouring channel 34 are arranged such that the entire skeleton essentially except for the opening of the pouring channel 34 and the opening of the outer capsule 3.1 is enclosed by the membrane 2.
  • the membrane 2 is fastened around the outer capsule by an outer membrane fixing means, which for example consists of a fixing ring 10 (shown on the left side of the figure) arranged in a form-fitting manner around the outer capsule or by a correspondingly positive design of the edge areas of the closing element 3.2 (on shown on the right side of the figure). If the membrane 2 is fastened to the outer capsule 3.1 by the closing element 3.2, it is necessary that the closing element 3.2, as shown in the figure for the battery compartment 33, also have a removable partial area or at least one opening for the pouring channel 34.
  • the membrane 2 is fastened with an inner membrane fixing means, wherein it spans the speaker opening (as shown) or can have a further opening in this area.
  • the inner membrane fixation means is, for example, the perforated inner closing element 4.2 which fits the opening of the inner capsule 4.1 and which holds the membrane 2 around the opening of the capsule 4.1 in such a way that the casting compound cannot enter the opening which spans the capsule opening Part 21 of the membrane 2 protects mechanically in use and does not represent an obstacle to the sound of the loudspeaker (sound passage openings).
  • That part of the opening of the outer capsule 3.1 which lies above the microphone compartment 31.1 can also be covered with a membrane. As shown in FIG. 1, this can be achieved with a separate piece 22 of the membrane clamped between the closing element 4.2 and the capsule wall, or in such a way that the membrane 2 also stretches in one piece over this opening, being held in the same way as at the Opening the inner capsule 3.1.
  • the closing element 3.2 is advantageously perforated.
  • the membrane 2 can also be welded or glued to the capsules or the corresponding closing elements, as already mentioned.
  • FIGS. 1 and 2 show a further embodiment of the hearing aid according to the invention.
  • the principle in turn corresponds to that described in connection with FIG. 1 and also the basic components of the hearing aid, so that both no longer need to be described.
  • the difference from the hearing aids according to FIGS. 1 and 2 is that the connecting element 5 is hollow and serves as a pressure compensation channel, for which purpose corresponding mouth openings 45 and 35 are provided in the inner (4) and in the outer support element 3.
  • the pouring opening 34 is arranged such that it opens into the battery compartment 33.
  • the inner end face IS is covered with a separate membrane piece 46, the area of the microphone 31 and the outer mouth opening 45 of the pressure compensation channel with a separate membrane piece 36.
  • Microphone 31 and loudspeaker 41 are cast directly by the casting compound or can be surrounded on the molded body side with a sound insulation material 37.
  • FIG. 3 shows the hearing aid in the general state as it is delivered by the manufacturer.
  • Figure 4 shows the hearing aid in the ear canal G, ready for pouring.
  • the battery and the battery compartment cover are removed.
  • the separate membrane pieces 36 and 46 (FIG. 3) are removed, and by means of the pressure equalization channel with a wire 7, a protective element 48 is attached to the inner end face IS of the hearing aid, by means of which not only the eardrum is to be protected when pouring, but also to help position the not yet individualized hearing aid in the ear canal.
  • the protective element 48 consists for example of foam.
  • the wire 7 carrying the protective element can additionally serve as an aid for inserting the hearing aid into the auditory canal and for removing it.
  • the membrane Before pouring, that is to say in the general state of the hearing aid, the membrane must already have a shape corresponding to a certain extent to the auditory canal, so that in the individualized state of the hearing aid it spans the molded body without wrinkles. In particular, it should be possible to fasten it around its main opening (outer end face) and around the opening on the inner end face as wrinkle-free as possible. To do this, the membrane must be in the form of a sack that tapers away from the main opening. Such a membrane bag can, as shown in FIGS . 5a to 5c , be produced in different ways.
  • a bag S can be drawn from a flat piece ME of a membrane.
  • This method of production requires sufficient deformability of the membrane, but is particularly advantageous if the membrane is to span the inner end face of the hearing aid, that is, if the membrane bag is to have only one main opening but no further opening.
  • FIG. 5b shows a method for producing a membrane bag S, likewise from a flat membrane piece ME, from which a piece K is cut in the form of a unwound truncated cone. This piece of K is welded to the membrane bag S with a main opening H and a further opening W.
  • FIG. 5c shows the production of a membrane bag again with a main opening H and a further opening W from a piece of membrane hose MS by expanding its one end to a larger diameter.
  • this can be applied to a second layer (intermediate layer) which is arranged on the finished hearing aid between the membrane and the molded body, that is to say not with the skin of the Ear canal comes into contact.
  • this layer can be an open-cell foam or a mesh onto which the membrane is drawn. It turns out that such an intermediate layer can also facilitate the manufacture of the membrane bag.

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  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Otolaryngology (AREA)
  • Health & Medical Sciences (AREA)
  • Acoustics & Sound (AREA)
  • Signal Processing (AREA)
  • Prostheses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Headphones And Earphones (AREA)
  • Light Guides In General And Applications Therefor (AREA)
  • Battery Mounting, Suspending (AREA)
EP94810287A 1993-06-11 1994-05-17 Prothèse auditive à porter dans l'oreille et procédé pour sa fabrication Expired - Lifetime EP0629101B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH175793 1993-06-11
CH175793 1993-06-11
CH1757/93 1993-06-11

Publications (2)

Publication Number Publication Date
EP0629101A1 true EP0629101A1 (fr) 1994-12-14
EP0629101B1 EP0629101B1 (fr) 2001-09-05

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EP94810287A Expired - Lifetime EP0629101B1 (fr) 1993-06-11 1994-05-17 Prothèse auditive à porter dans l'oreille et procédé pour sa fabrication

Country Status (6)

Country Link
US (1) US5530763A (fr)
EP (1) EP0629101B1 (fr)
AT (1) ATE205357T1 (fr)
AU (1) AU677647B2 (fr)
DE (1) DE59409849D1 (fr)
DK (1) DK0629101T3 (fr)

Cited By (10)

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DE19843389C2 (de) * 1998-09-22 2002-07-11 Fariborz-Hassan Dirinpur Perforierte Otoplastik für Hörgeräte
EP1432285A2 (fr) * 2003-12-30 2004-06-23 Phonak Ag Revêtement hydrophobe des composants individuels des prothèses auditives
US7174028B1 (en) 2000-09-07 2007-02-06 Phonak Ag Method for manufacturing hearing aids, and a hearing aid
EP1060640B2 (fr) † 1998-03-02 2007-03-14 Phonak Ag Prothese auditive
DE102006014884B3 (de) * 2006-03-30 2007-08-23 Siemens Audiologische Technik Gmbh In-dem-Ohr-Hörvorrichtung mit Bandelement zur Befestigung des Faceplates
EP1758427A3 (fr) * 2005-08-26 2008-10-08 Siemens Audiologische Technik GmbH Prothèse auditive à porter dans l'oreille avec module électronique
EP2007171A3 (fr) * 2007-06-20 2009-11-11 Siemens Medical Instruments Pte. Ltd. Unité de fermeture avec support de composants pour un dispositif auditif
US8416975B2 (en) 2008-04-02 2013-04-09 Siemens Medical Instruments Pte. Ltd. Hearing aid housing
WO2020225365A1 (fr) * 2019-05-09 2020-11-12 Sivantos Pte. Ltd. Procédé permettant d'adapter un élément otoplastique d'un appareil auditif, appareil auditif et système d'appareil auditif

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EP0821543A3 (fr) * 1996-07-24 2004-06-02 Bernafon AG Membrane comme surface extérieure d'une prothèse auditive qui est individualisée par moulage d'un corps
EP0821541A3 (fr) * 1996-07-24 2004-06-02 Bernafon AG Prothèse auditive portable complètement dans le conduit auditif et individualisée par moulage d'un corps
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DK1432285T3 (en) * 2003-12-30 2016-08-01 Sonova Ag Hydrophobic coating of the individual components of the hearing instrument
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US20090320979A1 (en) * 2006-03-17 2009-12-31 Donaldson Company, Inc. Hearing Aid Microphone Cover
EP2060148B1 (fr) * 2006-08-31 2018-07-18 Widex A/S Filtre pour prothèse auditive et prothèse auditive
CA2601662A1 (fr) 2006-09-18 2008-03-18 Matthias Mullenborn Interface sans fil pour programmer des dispositifs d'aide auditive
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KR20170012487A (ko) 2014-05-30 2017-02-02 레볼 테크놀로지스 인코포레이티드 맞춤형 귀 삽입구
US10250964B2 (en) * 2017-05-10 2019-04-02 Logitech Europe S.A. Apparatus and method of forming a custom earpiece
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USD871130S1 (en) * 2018-03-02 2019-12-31 Gowanus Kitchen Lab, Llc Frywall structure
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US7372973B2 (en) 1998-03-02 2008-05-13 Phonak Ag Hearing aid
DE19843389C2 (de) * 1998-09-22 2002-07-11 Fariborz-Hassan Dirinpur Perforierte Otoplastik für Hörgeräte
WO2000074915A3 (fr) * 2000-09-07 2002-04-25 Phonak Ag Procede de production d'appareils auditifs, et appareil auditif
WO2000074915A2 (fr) * 2000-09-07 2000-12-14 Phonak Ag Procede de production d'appareils auditifs, et appareil auditif
US7174028B1 (en) 2000-09-07 2007-02-06 Phonak Ag Method for manufacturing hearing aids, and a hearing aid
US7267847B2 (en) 2003-12-30 2007-09-11 Phonak Ag Hydrophobic coating of individual components of hearing aid devices
EP1432285A3 (fr) * 2003-12-30 2004-12-22 Phonak Ag Revêtement hydrophobe des composants individuels des prothèses auditives
EP1432285A2 (fr) * 2003-12-30 2004-06-23 Phonak Ag Revêtement hydrophobe des composants individuels des prothèses auditives
EP1758427A3 (fr) * 2005-08-26 2008-10-08 Siemens Audiologische Technik GmbH Prothèse auditive à porter dans l'oreille avec module électronique
DE102006014884B3 (de) * 2006-03-30 2007-08-23 Siemens Audiologische Technik Gmbh In-dem-Ohr-Hörvorrichtung mit Bandelement zur Befestigung des Faceplates
EP1841287A2 (fr) * 2006-03-30 2007-10-03 Siemens Audiologische Technik GmbH Prothèse auditive intra-auriculaire avec un élément de bande pour la fixation de la plaque frontale
EP1841287A3 (fr) * 2006-03-30 2009-10-21 Siemens Audiologische Technik GmbH Prothèse auditive intra-auriculaire avec un élément de bande pour la fixation de la plaque frontale
US8045740B2 (en) 2006-03-30 2011-10-25 Siemens Audiologische Technik Gmbh In-the-ear hearing apparatus having a band element for attaching a housing part
EP2007171A3 (fr) * 2007-06-20 2009-11-11 Siemens Medical Instruments Pte. Ltd. Unité de fermeture avec support de composants pour un dispositif auditif
US8605926B2 (en) 2007-06-20 2013-12-10 Siemens Medical Instruments Pte. Ltd. Sealing unit with component mount for a hearing apparatus
US8416975B2 (en) 2008-04-02 2013-04-09 Siemens Medical Instruments Pte. Ltd. Hearing aid housing
WO2020225365A1 (fr) * 2019-05-09 2020-11-12 Sivantos Pte. Ltd. Procédé permettant d'adapter un élément otoplastique d'un appareil auditif, appareil auditif et système d'appareil auditif
US11818551B2 (en) 2019-05-09 2023-11-14 Sivantos Pte. Ltd. Method for adapting an otoplastic of a hearing aid, hearing aid, and hearing aid system

Also Published As

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US5530763A (en) 1996-06-25
DK0629101T3 (da) 2001-12-31
AU6332694A (en) 1994-12-15
DE59409849D1 (de) 2001-10-11
EP0629101B1 (fr) 2001-09-05
ATE205357T1 (de) 2001-09-15
AU677647B2 (en) 1997-05-01

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