EP0187147A1 - Präparat zur haar- und nagelpflege und verfahren zu seiner herstellung - Google Patents
Präparat zur haar- und nagelpflege und verfahren zu seiner herstellungInfo
- Publication number
- EP0187147A1 EP0187147A1 EP19850902629 EP85902629A EP0187147A1 EP 0187147 A1 EP0187147 A1 EP 0187147A1 EP 19850902629 EP19850902629 EP 19850902629 EP 85902629 A EP85902629 A EP 85902629A EP 0187147 A1 EP0187147 A1 EP 0187147A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- mass
- blood plasma
- hair
- preparation
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q3/00—Manicure or pedicure preparations
- A61Q3/02—Nail coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/983—Blood, e.g. plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
Definitions
- the invention relates to a preparation for hair and nail care, in particular in the form of a shampoo, hair rinse, hair conditioning agent and hair tonic or in the form of nail polish, and a process for its preparation.
- the hair care products can be divided into several groups according to their type of application and their intended use.
- the main groups are hair shampoos, hair rinses, hair conditioning agents and the different hair lotions.
- the primary task of hair shampoos is to clean hair and scalp.
- they contain surface-active substances, primarily surfactants.
- the surface-active substances have a drying effect on the hair and scalp.
- the shampoos contain various active ingredients in addition to the surface-active substances, including rüokfettstoff and skin-closer substances.
- the hair shampoos (and also the other hair care products) also contain fragrances and dyes and, if necessary, preservatives.
- protein and amino acid-containing substances for example plant extracts, collagen, etc., are used as active ingredients.
- the active ingredients contained in the hair shampoo can only partially exert their effect because the treatment with shampoo is followed by rinsing the hair and a significant part of the active ingredients is thereby removed. If you leave that
- hair rinses are not washed off with water. Because they remain on the scalp, their active ingredient content is generally lower than that of shampoos.
- the main purpose of hair detergents is that Compensate for the skin and hair damaging effects of the shampoo, improve the condition of the hair and scalp.
- the hair conditioning agents contain the active ingredients, mostly natural proteins, without surfactants in the form of an emulsion.
- hair lotions also contain extracts of natural origin, mostly vegetable extracts or proteins of animal origin.
- the active ingredients must have a composite beneficial effect. They have to give the hair part of its fat content, maintain its physical properties (elasticity, combability, shine, etc.), protect the scalp from drying out and allow the substances necessary for hair formation to penetrate the scalp.
- Protein-based active ingredients are used in the manufacture of nail polish, which serve to protect the consistency of the nails and to prevent or weaken the brittleness of the nails.
- One of the biggest disadvantages of nail polishes is that the lacquer film becomes brittle and splinters off. The result of this is that the lacquer layer must be removed much more frequently than would be due to the natural wear of the lacquer.
- the object of the invention is to provide a hair and nail care product which meets the diverse requirements outlined above and, by using a natural active ingredient which is more effective than the known ones, ensures more effective hair and nail care.
- the invention is based on the knowledge that, among the natural active ingredients, all those which make it possible to achieve the stated goals are contained in the blood owing to its protein and amino acid composition.
- the use of blood in its natural form for cosmetic purposes is hindered by numerous circumstances, including its Tendency to curdle and spoil, its color, etc.
- the industrial use of blood from slaughterhouses is well known. It is treated with an anticoagulator and then separated into dioc blood and blood plasma in the separator.
- the blood plasma is mainly used in the food industry.
- proteins it mainly contains globular proteins, lipoproteins and fibrinogen.
- a blood plasma extract which can be used according to the invention as an active ingredient for hair and nail care products can be obtained from blood plasma by drying.
- the blood plasma extract contains a relatively large amount of salt, since the salt concentration increases with drying and concentration as the water emerges.
- the composition of the blood plasma, the dried blood plasma and the content of essential amino acids in the blood plasma are given below (Grant, R.A .: Applied protein chemistry, Applied Sei. Publishers, Ltd., London, 1980). Average composition of the blood plasma making up 60% of the total blood water 90.8% by mass
- Threonine 6.2 isoleucine 2.9
- the protein content of the dried blood plasma is therefore 71.9% and that of the blood plasma is only 7.9%. This almost tenfold amount results from the considerable reduction in the water content.
- the 16.5% salt contained in the dried blood plasma is an obstacle for most cosmetic applications, primarily the salts originating from the anticoagulator pose a danger. These are different phosphates that coagulate the proteins on the surface of the skin to precipitate.
- the high salt content has a dehydrating effect, dries out the skin and can also irritate it.
- the blood plasma extract can therefore only be used in small quantities for cosmetic purposes.
- the thickening of the blood plasma cannot only be done by drying.
- ultrafiltration particles with a molecular weight of only 16000-18000 can be separated from the liquid phase.
- the molar mass of the valuable proteins and amino acids contained in the blood plasma is above this range, so they can be separated from the liquid phase by ultrafiltration.
- ultrafiltration not only separates the liquid, but also the salts dissolved in it, ie the extract has a much lower salt content.
- the blood plasma thickened by ultrafiltration only has a salt content of about 4.1%, of which only about 2.5% are residues originating from the anticoagulator. This amount of salt can already be described as negligible.
- the invention accordingly relates to a preparation for
- Hair rinses, hair conditioners or hair lotions or nail polish It is characteristic of the preparation according to the invention that it contains at least an amount of blood plasma extract obtained from slaughterhouse blood as an active ingredient
- the salt concentration in the blood plasma extract is at most 6%, in particular below 4.2%. This concentration can only be achieved by ultrafiltration.
- the blood plasma extract is not broken down into fractions, it retains its original composition and that derived from the anticoagulator added to the slaughterhouse blood
- Residues make up a maximum of 60% of the permissible salinity.
- the protein and amino acid composition of the blood plasma extract is in harmony with that of the blood plasma and the protein concentration in the extract is at least 60%.
- the composition of the hair proteins should be briefly discussed.
- the keratin is largely made up of cystine and methionine, so applying these amino acids to the scalp promotes the development of the hair structure.
- the amino acid composition of the fibrinogen contained in the plasma is more favorable compared to that of other biologically active substances (collagen, elastin).
- the threonine content of the fibrinogen is three and six times as high, and the leucine and isoleucine content is about three times that of the collagen.
- Fibrinogen contains five times as much tyrosine and more than twice as much lysine as collagen, and its lysine content is sixteen times that of elastin.
- the arginine content of the blood plasma is six times that of the ELa stins. Tryptophan is not found at all in collagen and elastin, but in significant amounts in fibrinogen.
- Collagen contains no cystine
- elastin contains only one seventh of the cystine content of fibrinogen.
- Collagen and elastin are considered to be extremely advantageous as active ingredients for hair care products, the comparative figures given therefore show some of the advantages that result from the use of blood plasma.
- the mechanism of action has not yet been fully clarified, but the fact that, apart from the higher concentration of the amino acids, their state of binding is also more favorable for incorporation into the organism than the binding of the same amino acids to non-body carriers.
- the globular proteins contained in the blood plasma extract have hydrating properties and ensure the natural elasticity of the scalp.
- the lipoproteins contained in the plasma are fatty, so they mitigate the fat-extracting effects of the surface-active substances. As a result of the properties described, the proteins not only nourish the skin but are adsorbed on the scalp, protect them from drying out, hydrate them and counteract irritation.
- the fatty substances influence the mechanical properties of the hair in a favorable direction.
- the active ingredient according to the invention is particularly suitable for use in hair care products.
- the similarity in the structure of hair and nails shows that the same active ingredient can also be used with advantage in nail polish; In nail polish, the active ingredient also increases the elasticity of the lacquer layer.
- the blood plasma extract is first swollen in water, the remaining additives are added to the swollen mixture, and occasionally it is homogenized or left to stand. This applies primarily to hair shampoos and conditioners; in the latter the active substance content is expediently 0.4-2% by mass.
- the conditioning agents contain aqueous emulsions instead of surfactants, and the lipoproteins stabilize the water / oil emulsions.
- the preparation of hair shampoo is based on the following composition: 35-40% by mass, preferably 40% by mass, sodium lauryl ether sulfate, 8-12% by mass, preferably 10% by mass, betaine derivative, for example the hand ice cream product Zelbetain, 1.5-2.5% by mass %, preferably 2 mass%, fatty acid diethanolamide, 40-50 mass%, preferably 45 mass%, distilled water, 0.3-0.7 mass%, preferably 0.5 mass%, preservative, 0.8-1.5 mass %, preferably 1 mass%, blood plasma extract.
- the blood plasma extract is swollen in water, then the remaining components are added with stirring. Fragrances are added to the homogeneously stirred mixture at 30 ° C.
- the shampoo is applied to the head during shampooing and expediently left to act for a few minutes so that the active ingredient can diffuse into the scalp. It has been shown that the shampoo ensures elasticity, appropriate consistency, good combability and a pleasant fall of the hair.
- Example 3 To produce a hair rinse aid, 0.4-2% by mass, preferably 0.8% by mass, of blood plasma extract swollen in water, 0.08% by mass of the commercial product Antara 430 and 0.3% by mass of citric acid are added. The water content is about 99% by mass. The use of this hair conditioner gives permanently groomed hair.
- Example 3 To produce a hair rinse aid, 0.4-2% by mass, preferably 0.8% by mass, of blood plasma extract swollen in water, 0.08% by mass of the commercial product Antara 430 and 0.3% by mass of citric acid are added. The water content is about 99% by mass. The use of this hair conditioner gives permanently groomed hair.
- Example 3 To produce a hair rinse aid, 0.4-2% by mass, preferably 0.8% by mass, of blood plasma extract swollen in water, 0.08% by mass of the commercial product Antara 430 and 0.3% by mass of citric acid are added. The water content is about 99% by mass. The use of this hair conditioner gives permanently groomed hair.
- a beneficial composition for hair tonic 85.5% alcohol by mass, 9.5% distilled water, 3% isopropyl myristate, 0.5% blood plasma extract, 1.5% fragrance.
- the plasma extract is swollen in water, the other components are dissolved in alcohol and added. The mixture is left to stand for 1-2 weeks and, if necessary, filtered.
- the hair tonic was tested with a good result
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Description
Claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU234784 | 1984-06-19 | ||
HU234784A HU193289B (en) | 1984-06-19 | 1984-06-19 | Cosmetical composition for treating hair and nail containing blood plasma concentrate as active agent |
Publications (1)
Publication Number | Publication Date |
---|---|
EP0187147A1 true EP0187147A1 (de) | 1986-07-16 |
Family
ID=10958947
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19850902629 Withdrawn EP0187147A1 (de) | 1984-06-19 | 1985-06-19 | Präparat zur haar- und nagelpflege und verfahren zu seiner herstellung |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0187147A1 (de) |
HU (1) | HU193289B (de) |
WO (1) | WO1986000222A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5177061A (en) * | 1985-02-08 | 1993-01-05 | Procyte Corporation | Method for stimulating hair growth using GHL-Cu complexes |
US5120831A (en) * | 1985-02-08 | 1992-06-09 | Procyte Corporation | Metal-peptide compositions |
EP0314755B1 (de) * | 1987-05-11 | 1994-08-24 | Procyte Corporation | Gebrauch von GHL-Cu Derivaten für die Herstellung eines Medikaments zur Stimulierung des Haarwachstums |
JPH0372413A (ja) * | 1989-08-10 | 1991-03-27 | Japan Happy:Kk | 毛髪のコールドパーマネントウエーブ処理剤と染毛剤 |
US5023237A (en) * | 1989-08-30 | 1991-06-11 | Procyte Corporation | Methods and compositions for healing ulcers |
US5145838A (en) * | 1989-08-30 | 1992-09-08 | Procyte Corporation | Methods and compositions for healing ulcers |
US5059588A (en) * | 1989-10-13 | 1991-10-22 | Procyte Corporation, Incorporated | Methods and compositions for healing bone using gly his lys: copper |
US5118665A (en) * | 1990-02-09 | 1992-06-02 | Procyte Corporation | Anti-oxidative and anti-inflammatory metal:peptide complexes and uses thereof |
US5164367A (en) * | 1990-03-26 | 1992-11-17 | Procyte Corporation | Method of using copper(ii) containing compounds to accelerate wound healing |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1038415A (en) * | 1964-04-17 | 1966-08-10 | Curtis Helene Ind Inc | Cosmetic preparations containing albumins |
FR2119904A6 (de) * | 1970-12-28 | 1972-08-11 | Gen Chemicals Cosmet | |
FR2442632A1 (fr) * | 1978-12-01 | 1980-06-27 | Oreal | Utilisation de certains copolymeres cationiques pour les soins des ongles et compositions les contenant |
FR2455457A1 (fr) * | 1979-05-03 | 1980-11-28 | Oreal | Compositions contenant certains derives de n-oxypyridyl-2-thiol pour le renforcement et la revitalisation des ongles fragiles ou alteres |
FR2472385A1 (fr) * | 1979-12-27 | 1981-07-03 | Sederma Sa | Nouveaux extraits biologiques utilisables en cosmetologie, et procedes d'obtention de ces extraits |
US4530828A (en) * | 1982-09-16 | 1985-07-23 | Richardson-Vicks Inc. | Nail conditioner |
-
1984
- 1984-06-19 HU HU234784A patent/HU193289B/hu not_active IP Right Cessation
-
1985
- 1985-06-19 EP EP19850902629 patent/EP0187147A1/de not_active Withdrawn
- 1985-06-19 WO PCT/HU1985/000038 patent/WO1986000222A1/de not_active Application Discontinuation
Non-Patent Citations (1)
Title |
---|
See references of WO8600222A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO1986000222A1 (en) | 1986-01-16 |
HU193289B (en) | 1987-09-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19860210 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE FR GB IT LI LU NL SE |
|
17Q | First examination report despatched |
Effective date: 19870610 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 19861021 |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: FUELOEP, LASZLONE Inventor name: BASA, ERZSEBET Inventor name: GABOR, MIKLOSNE Inventor name: HORVATH, BELA Inventor name: LACZKO, ISTVAN Inventor name: VARRO, GYOERGYNE Inventor name: CSELOVSZKY, JANOSNE Inventor name: KOVACS, ESZTER Inventor name: BANETH, PETER |