EG20085A - Process for preparing of imidazopyridine PAF/H2 antagonists - Google Patents

Process for preparing of imidazopyridine PAF/H2 antagonists

Info

Publication number: EG20085A
Authority: EG; Egypt
Prior art keywords: pct; paf; antagonists; sec; imidazopyridine
Prior art date: 1991-02-13

Application number

EG8792A

Other languages

English (en)

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-02-13

Filing date

1992-02-10

Publication date

1997-05-31

1992-02-10 Application filed by Pfizer filed Critical Pfizer

1997-05-31 Application granted granted Critical

1997-05-31 Publication of EG20085A publication Critical patent/EG20085A/xx

Links

GAMYYCRTACQSBR-UHFFFAOYSA-N 4-azabenzimidazole Chemical compound C1=CC=C2NC=NC2=N1 GAMYYCRTACQSBR-UHFFFAOYSA-N 0.000 title 1
229940122957 Histamine H2 receptor antagonist Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
206010039085 Rhinitis allergic Diseases 0.000 abstract 1
230000000172 allergic effect Effects 0.000 abstract 1
201000010105 allergic rhinitis Diseases 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
208000010668 atopic eczema Diseases 0.000 abstract 1
125000005605 benzo group Chemical group 0.000 abstract 1
125000006355 carbonyl methylene group Chemical group [H]C([H])([*:2])C([*:1])=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
229960001340 histamine Drugs 0.000 abstract 1
230000004968 inflammatory condition Effects 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Immunology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Prostheses (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cosmetics (AREA)
Steroid Compounds (AREA)

EG8792A 1991-02-13 1992-02-10 Process for preparing of imidazopyridine PAF/H2 antagonists EG20085A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB919102997A GB9102997D0 (en)	1991-02-13	1991-02-13	Therapeutic agents

Publications (1)

Publication Number	Publication Date
EG20085A true EG20085A (en)	1997-05-31

Family

ID=10689943

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG8792A EG20085A (en)	1991-02-13	1992-02-10	Process for preparing of imidazopyridine PAF/H2 antagonists

Country Status (29)

Country	Link
US (1)	US5358953A (zh)
EP (1)	EP0572425B1 (zh)
JP (1)	JP2506541B2 (zh)
KR (1)	KR970005302B1 (zh)
CN (1)	CN1040326C (zh)
AT (1)	ATE109482T1 (zh)
AU (1)	AU650322B2 (zh)
BR (1)	BR9205615A (zh)
CA (1)	CA2099381C (zh)
CZ (1)	CZ280504B6 (zh)
DE (1)	DE69200304T2 (zh)
DK (1)	DK0572425T3 (zh)
EG (1)	EG20085A (zh)
ES (1)	ES2059212T3 (zh)
FI (1)	FI933531A (zh)
GB (1)	GB9102997D0 (zh)
HU (2)	HUT65947A (zh)
IE (1)	IE65125B1 (zh)
IL (1)	IL100887A (zh)
MX (1)	MX9200589A (zh)
MY (1)	MY108437A (zh)
NO (1)	NO300592B1 (zh)
NZ (1)	NZ241597A (zh)
PL (1)	PL169304B1 (zh)
RU (1)	RU2114845C1 (zh)
TW (1)	TW227000B (zh)
WO (1)	WO1992014734A1 (zh)
YU (1)	YU48238B (zh)
ZA (1)	ZA921005B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2042421B1 (es) *	1992-05-22	1994-08-01	Uriach & Cia Sa J	Procedimiento para la obtencion de la 8-cloro-11-1-(5-metil-3-piridil)metil-4-piperidiliden-6,11-dihidro-5h-benzo5,6ciclohepta1,2-bpiridina.
AU3186395A (en) *	1994-08-10	1996-03-07	British Biotech Pharmaceuticals Limited	Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists
ES2087038B1 (es) *	1994-11-07	1997-03-16	Uriach & Cia Sa J	Nuevas piperidinas con actividad antagonista del paf.
US5567711A (en) *	1995-04-19	1996-10-22	Abbott Laboratories	Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) *	1995-04-28	1995-06-14	British Biotech Pharm	Benzimidazole derivatives
GB2308593B (en) *	1995-08-05	1999-01-27	British Biotech Pharm	Imidazopyridine derivatives
CA2417960C (en)	2000-08-04	2012-07-10	Dmi Biosciences, Inc.	Method of using diketopiperazines and composition containing them
CN102210852B (zh)	2003-05-15	2016-10-19	安皮奥制药股份有限公司	T-细胞介导的疾病的治疗
US7687515B2 (en) *	2006-01-17	2010-03-30	N.V. Organon	6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
US8377967B2 (en)	2008-01-30	2013-02-19	Nippon Zoki Pharmaceutical Co., Ltd.	Piperidine derivative
EP2300011A4 (en)	2008-05-27	2012-06-20	Dmi Life Sciences Inc	METHODS AND THERAPEUTIC COMPOUNDS
CN103619839B (zh) *	2011-06-28	2016-06-01	福建省闽东力捷迅药业有限公司	抗-***反应的苯并环庚并噻吩衍生物
MY167804A (en)	2011-10-10	2018-09-26	Ampio Pharmaceuticals Inc	Treatment of degenerative joint disease
EP2765968A4 (en)	2011-10-10	2015-01-21	Ampio Pharmaceuticals Inc	IMPLANTABLE MEDICAL DEVICES HAVING INCREASED IMMUNE TOLERANCE, AND METHODS OF MANUFACTURING AND IMPLANTATION
US10881710B2 (en) *	2011-10-28	2021-01-05	Ampio Pharmaceuticals, Inc.	Treatment of rhinitis
EP2968315B1 (en)	2013-03-15	2020-06-03	Ampio Pharmaceuticals, Inc.	Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
JP6723222B2 (ja)	2014-08-18	2020-07-15	アンピオファーマシューティカルズ，インコーポレイテッド	関節病態の治療
WO2016209969A1 (en)	2015-06-22	2016-12-29	Ampio Pharmaceuticals, Inc.	Use of low molecular weight fractions of human serum albumin in treating diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE68920998T2 (de) *	1988-03-15	1995-06-22	Searle & Co	1H/3H-[4-(N,N-CYCLOALKYL UND/ODER VERZWEIGTES ALKYLCARBOXAMIDO)-BENZYL]IMDAZO[4,5-c]PYRIDINE ALS PAF-ANTAGONISTEN.
JP2511550B2 (ja) *	1988-04-28	1996-06-26	シェリング・コーポレーション	融合多環式化合物、組成物、製造方法およびｐａｆ拮抗、抗ヒスタミンおよび／または抗炎症剤としてのその使用
US5250681A (en) *	1988-06-02	1993-10-05	Ajinomoto Co., Inc.	Piperidine derivatives and hypotensives containing the same
US5114919A (en) *	1990-02-26	1992-05-19	Merck & Co., Inc.	Adjuncts in cancer chemotherapy
EP0533695B1 (en) *	1990-05-09	1994-10-05	Pfizer Inc.	IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY

1991
- 1991-02-13 GB GB919102997A patent/GB9102997D0/en active Pending
1992
- 1992-01-24 HU HU9302327A patent/HUT65947A/hu unknown
- 1992-01-24 CA CA002099381A patent/CA2099381C/en not_active Expired - Fee Related
- 1992-01-24 JP JP4503504A patent/JP2506541B2/ja not_active Expired - Fee Related
- 1992-01-24 DK DK92902889.2T patent/DK0572425T3/da active
- 1992-01-24 ES ES92902889T patent/ES2059212T3/es not_active Expired - Lifetime
- 1992-01-24 WO PCT/EP1992/000163 patent/WO1992014734A1/en active IP Right Grant
- 1992-01-24 PL PL92300296A patent/PL169304B1/pl unknown
- 1992-01-24 RU RU93054165A patent/RU2114845C1/ru active
- 1992-01-24 AU AU11683/92A patent/AU650322B2/en not_active Ceased
- 1992-01-24 AT AT92902889T patent/ATE109482T1/de not_active IP Right Cessation
- 1992-01-24 EP EP92902889A patent/EP0572425B1/en not_active Expired - Lifetime
- 1992-01-24 BR BR9205615A patent/BR9205615A/pt not_active Application Discontinuation
- 1992-01-24 DE DE69200304T patent/DE69200304T2/de not_active Expired - Fee Related
- 1992-01-24 KR KR1019930702352A patent/KR970005302B1/ko not_active IP Right Cessation
- 1992-01-24 US US08/087,736 patent/US5358953A/en not_active Expired - Fee Related
- 1992-02-06 IL IL10088792A patent/IL100887A/en not_active IP Right Cessation
- 1992-02-10 EG EG8792A patent/EG20085A/xx active
- 1992-02-10 TW TW081100891A patent/TW227000B/zh active
- 1992-02-11 MX MX9200589A patent/MX9200589A/es unknown
- 1992-02-12 IE IE920449A patent/IE65125B1/en not_active IP Right Cessation
- 1992-02-12 YU YU14392A patent/YU48238B/sh unknown
- 1992-02-12 CZ CS92425A patent/CZ280504B6/cs not_active IP Right Cessation
- 1992-02-12 ZA ZA921005A patent/ZA921005B/xx unknown
- 1992-02-12 MY MYPI92000223A patent/MY108437A/en unknown
- 1992-02-12 NZ NZ241597A patent/NZ241597A/en unknown
- 1992-02-13 CN CN92100974A patent/CN1040326C/zh not_active Expired - Fee Related
1993
- 1993-08-10 FI FI933531A patent/FI933531A/fi not_active Application Discontinuation
- 1993-08-13 NO NO932889A patent/NO300592B1/no unknown
1995
- 1995-06-09 HU HU95P/P00175P patent/HU211202A9/hu unknown

Also Published As

Publication number	Publication date
RU2114845C1 (ru)	1998-07-10
NZ241597A (en)	1993-04-28
CN1040326C (zh)	1998-10-21
HU9302327D0 (en)	1993-10-28
AU1168392A (en)	1992-09-15
IL100887A0 (en)	1992-11-15
HUT65947A (en)	1994-08-29
AU650322B2 (en)	1994-06-16
IE65125B1 (en)	1995-10-04
NO932889D0 (no)	1993-08-13
CA2099381A1 (en)	1992-08-14
JPH06504992A (ja)	1994-06-09
YU14392A (sh)	1994-11-15
DK0572425T3 (da)	1994-09-12
NO932889L (no)	1993-08-13
CS42592A3 (en)	1992-09-16
CZ280504B6 (cs)	1996-02-14
ZA921005B (en)	1993-08-12
FI933531A0 (fi)	1993-08-10
DE69200304T2 (de)	1994-12-08
MY108437A (en)	1996-09-30
TW227000B (zh)	1994-07-21
GB9102997D0 (en)	1991-03-27
WO1992014734A1 (en)	1992-09-03
HU211202A9 (en)	1995-11-28
MX9200589A (es)	1992-10-01
IL100887A (en)	1996-01-19
DE69200304D1 (de)	1994-09-08
NO300592B1 (no)	1997-06-23
JP2506541B2 (ja)	1996-06-12
IE920449A1 (en)	1992-08-12
BR9205615A (pt)	1994-05-17
CA2099381C (en)	1996-07-09
FI933531A (fi)	1993-08-10
YU48238B (sh)	1997-08-22
ES2059212T3 (es)	1994-11-01
EP0572425B1 (en)	1994-08-03
US5358953A (en)	1994-10-25
KR970005302B1 (ko)	1997-04-15
CN1064275A (zh)	1992-09-09
ATE109482T1 (de)	1994-08-15
EP0572425A1 (en)	1993-12-08
PL169304B1 (pl)	1996-06-28

Publication	Publication Date	Title
EG20085A (en)	1997-05-31	Process for preparing of imidazopyridine PAF/H2 antagonists
YU48426B (sh)	1998-07-10	Novi supstituisani pirazolilpirazoli, postupak njihovog dobijanja, medjuproizvodi za njihovo dobijanje i primena kao sredstava sa herbicidnim delovanjem
MXPA02011417A (es)	2003-04-25	1-aminoalquil-lactamas sustituidas y su uso como antagonistas de receptores muscarinicos.
YU84791A (sh)	1994-06-10	Biciklicni 1-aza-cikloalkalni
FI922341A0 (fi)	1992-05-22	Piperidin- och pyrrolidinderivat.
RU93054165A (ru)	1996-09-10	Производные имидазопиридина, способ их получения, фармацевтическая композиция, способ лечения
EP0335979A4 (en)	1992-02-26	Thienopyrimidine derivatives
ES8202818A1 (es)	1982-03-01	Un procedimiento para preparar derivados de tetrazolilcuma- rina
SG164268A1 (en)	2010-09-29	Quinolin-4-yl derivatives i
DE3855902D1 (de)	1997-06-12	Herstellungsverfahren für 2,5-Diamino-6-nitro-pyridinderivate sowie neue 2,5-Diamino-6-nitro-pyridinderivate
HUT61718A (en)	1993-03-01	Process for producing phenylethanolamino and phenylethanolamino methyltetraline derivatives
YU4393A (sr)	1996-01-09	Supstituisani heksahidroazepinoni i tetrahidrobenzazepinoni
SE8801964D0 (sv)	1988-05-26	New 5-(omega-ammonio acyloxy methylene) tetrahydrofurans and tetrahydrothiophenes
AU564799B2 (en)	1987-08-27	Composition for prophylactic and preventative of ketosis in livestock
HU900728D0 (en)	1990-04-28	Process for preparation of calcium antagonistics
PT100223A (pt)	1993-09-30	Processo para a preparacao de imidazopiridinas antagonistas de paf/h1
NZ304988A (en)	2000-01-28	1-omega-(3,4-dihydro-2-naphthalenyl)alkyl] cyclic amine derivatives and their use
DK0441515T3 (da)	1996-02-05	Tetralin- og chromanderivater i behandlingen af astma, artritis og beslægtede sygdomme
FI973558A (fi)	1997-08-29	Menetelmä terapeuttisesti käytt¦kelpoisten 2-metyyli-imidatsoÄ4,5-cÜpyrid-1-yylijohdannaisten valmistamiseksi
PH15866A (en)	1983-04-13	Substituted 4-amino 2,6-diaryl-tetrahydrothiopyrans and salts thereof,and use as antidepressants
KR840006998A (ko)	1984-12-04	1,8-나프티리딘과 1.5,8-아자나프티리딘 유도체의 제조방법