EE9900044A - Farmatseutilised tooted veresoonte endoteelirakkude kahjustuste tagajärjel tekkinud haiguste raviks ja vältimiseks - Google Patents
Farmatseutilised tooted veresoonte endoteelirakkude kahjustuste tagajärjel tekkinud haiguste raviks ja vältimiseksInfo
- Publication number
- EE9900044A EE9900044A EEP199900044A EE9900044A EE9900044A EE 9900044 A EE9900044 A EE 9900044A EE P199900044 A EEP199900044 A EE P199900044A EE 9900044 A EE9900044 A EE 9900044A EE 9900044 A EE9900044 A EE 9900044A
- Authority
- EE
- Estonia
- Prior art keywords
- pct
- prevention
- treatment
- vascular endothelial
- endothelial cell
- Prior art date
Links
- 230000005779 cell damage Effects 0.000 title 1
- 208000037887 cell injury Diseases 0.000 title 1
- 230000006806 disease prevention Effects 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 229940127557 pharmaceutical product Drugs 0.000 title 1
- 210000003556 vascular endothelial cell Anatomy 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000002889 endothelial cell Anatomy 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002443 hydroxylamines Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9602204A HUP9602204D0 (en) | 1996-08-09 | 1996-08-09 | Pharmaceutical compositions for treating diseases connected with the disfunction of the vascular endothelial cells |
HU9701349A HUP9701349A1 (hu) | 1997-08-04 | 1997-08-04 | Gyógyászati készítmények a vaszkuláris endoteliális sejtek rendellenes működésével összefüggő betegségek gyógyítására vagy megelőzésére |
PCT/HU1997/000044 WO1998006400A2 (en) | 1996-08-09 | 1997-08-06 | Pharmaceutical products for curing and preventing illnesses connected with the malfunction of vascular endothelial cells |
Publications (2)
Publication Number | Publication Date |
---|---|
EE9900044A true EE9900044A (et) | 1999-08-16 |
EE04044B1 EE04044B1 (et) | 2003-06-16 |
Family
ID=90014231
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EEP199900044A EE04044B1 (et) | 1996-08-09 | 1997-08-06 | Farmatseutilised tooted veresoonte endoteelirakkude kahjustuste tagajärjel tekkinud haiguste raviksja vältimiseks |
Country Status (20)
Country | Link |
---|---|
US (1) | US6143741A (et) |
EP (1) | EP0966283B1 (et) |
JP (1) | JP2001504446A (et) |
AT (1) | ATE329592T1 (et) |
AU (1) | AU739614B2 (et) |
BG (1) | BG64456B1 (et) |
CA (1) | CA2262997C (et) |
CZ (1) | CZ298542B6 (et) |
DE (1) | DE69736130T2 (et) |
DK (1) | DK0966283T3 (et) |
EE (1) | EE04044B1 (et) |
ES (1) | ES2267148T3 (et) |
HK (1) | HK1025506A1 (et) |
IL (1) | IL128256A (et) |
NO (1) | NO325109B1 (et) |
PT (1) | PT966283E (et) |
RS (1) | RS49719B (et) |
SK (1) | SK284301B6 (et) |
UA (1) | UA64716C2 (et) |
WO (1) | WO1998006400A2 (et) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU9701081D0 (en) | 1997-06-23 | 1997-08-28 | Gene Research Lab Inc N | Pharmaceutical composition of antitumoral activity |
HU226617B1 (en) * | 1998-12-14 | 2009-04-28 | Cytrx Corp | Optically active pyridyl-4h-1,2,4-oxadiazine derivatives, and pharmaceutical composition containing the compound as active ingredient |
HUP9900475D0 (en) * | 1999-02-26 | 1999-04-28 | Biorex Kutato Fejlesztoe Kft | O-(3-piperidino-2-hydroxy-1-propyl)-hiyroximic acid-halogenid derivative, it's use for treating insulin resistance, and pharmaceutical compositions containing them as active component |
RS60604A (en) * | 2002-01-11 | 2006-12-15 | Biorex Kutato Es Feyleszto Rt. | Carboxamidine derivatives and their use in the treatment of vascular diseases |
HUP0303584A3 (en) | 2003-10-30 | 2009-12-28 | Cytrx Corp | Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases |
WO2008039514A1 (en) * | 2006-09-26 | 2008-04-03 | Cytrx Corporation | Pharmaceutical compositions and methods for treating diseases associated with neurodegeneration |
MX2009005798A (es) * | 2006-12-01 | 2009-08-12 | Cytrx Corp | Recuperacion de apoplejia. |
TW200901958A (en) * | 2007-05-04 | 2009-01-16 | Cytrx Corp | Diabetic wound healing |
JP5429865B2 (ja) * | 2009-09-15 | 2014-02-26 | 学校法人日本大学 | 生体外創傷治癒試験用用具または創傷作製方法 |
HUP1100535A2 (en) * | 2011-09-26 | 2013-04-29 | Bracelia Invest Ltd | Pharmaceutical composition for enhancement of stem cell treatment |
US9802927B2 (en) | 2015-06-10 | 2017-10-31 | Denali Therapeutics, Inc. | Oxadiazine compounds and methods of use thereof |
CA3202568A1 (en) | 2020-11-19 | 2022-05-27 | Zevra Denmark A/S | Processes for preparing arimoclomol citrate and intermediates thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4187220A (en) * | 1977-08-30 | 1980-02-05 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. | New O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same |
HU207988B (en) * | 1988-10-20 | 1993-07-28 | Biorex Kutato Fejlesztoe Kft | Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components |
GB9017351D0 (en) * | 1990-08-08 | 1990-09-19 | Wellcome Found | Medicaments for treatment of atherosclerosis |
EP0758315B1 (en) * | 1994-05-06 | 1998-08-26 | Biorex Kutato Es Fejlesztö Rt. | Novel hydroximic acid derivatives, pharmaceutical compositions containing them and process for preparing same |
HU218480B (hu) * | 1995-06-15 | 2000-09-28 | BIOREX Kutató és Fejlesztő Rt. | Hidroxilaminszármazékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyszerkészítmények |
HU222994B1 (hu) * | 1995-11-02 | 2004-01-28 | BIOREX Kutató és Fejlesztő Rt. | Hidroxilaminszármazékok és azok alkalmazása sejtek molekuláris chaperon-termelésének fokozására alkalmas gyógyszerkészítmények előállítására |
-
1997
- 1997-06-08 UA UA99020697A patent/UA64716C2/uk unknown
- 1997-08-06 CA CA002262997A patent/CA2262997C/en not_active Expired - Fee Related
- 1997-08-06 PT PT97933813T patent/PT966283E/pt unknown
- 1997-08-06 CZ CZ0043599A patent/CZ298542B6/cs not_active IP Right Cessation
- 1997-08-06 EE EEP199900044A patent/EE04044B1/et not_active IP Right Cessation
- 1997-08-06 SK SK154-99A patent/SK284301B6/sk not_active IP Right Cessation
- 1997-08-06 US US09/230,941 patent/US6143741A/en not_active Expired - Fee Related
- 1997-08-06 AT AT97933813T patent/ATE329592T1/de active
- 1997-08-06 ES ES97933813T patent/ES2267148T3/es not_active Expired - Lifetime
- 1997-08-06 JP JP50952798A patent/JP2001504446A/ja not_active Ceased
- 1997-08-06 DE DE69736130T patent/DE69736130T2/de not_active Expired - Lifetime
- 1997-08-06 AU AU37049/97A patent/AU739614B2/en not_active Ceased
- 1997-08-06 EP EP97933813A patent/EP0966283B1/en not_active Expired - Lifetime
- 1997-08-06 RS YUP-51/99A patent/RS49719B/sr unknown
- 1997-08-06 WO PCT/HU1997/000044 patent/WO1998006400A2/en active IP Right Grant
- 1997-08-06 DK DK97933813T patent/DK0966283T3/da active
- 1997-08-06 IL IL12825697A patent/IL128256A/en not_active IP Right Cessation
-
1999
- 1999-02-05 NO NO19990547A patent/NO325109B1/no not_active IP Right Cessation
- 1999-02-22 BG BG103194A patent/BG64456B1/bg unknown
-
2000
- 2000-06-28 HK HK00103903A patent/HK1025506A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SK15499A3 (en) | 2000-02-14 |
EP0966283B1 (en) | 2006-06-14 |
IL128256A0 (en) | 2000-02-17 |
CA2262997C (en) | 2008-07-29 |
CZ298542B6 (cs) | 2007-10-31 |
UA64716C2 (en) | 2004-03-15 |
US6143741A (en) | 2000-11-07 |
DE69736130T2 (de) | 2007-01-04 |
IL128256A (en) | 2004-05-12 |
AU3704997A (en) | 1998-03-06 |
JP2001504446A (ja) | 2001-04-03 |
WO1998006400A3 (en) | 1998-03-26 |
NO325109B1 (no) | 2008-02-04 |
EP0966283A2 (en) | 1999-12-29 |
NO990547D0 (no) | 1999-02-05 |
NO990547L (no) | 1999-03-25 |
RS49719B (sr) | 2007-12-31 |
HK1025506A1 (en) | 2000-11-17 |
CZ43599A3 (cs) | 1999-07-14 |
EE04044B1 (et) | 2003-06-16 |
BG64456B1 (bg) | 2005-03-31 |
SK284301B6 (sk) | 2005-01-03 |
PT966283E (pt) | 2006-08-31 |
CA2262997A1 (en) | 1998-02-19 |
BG103194A (en) | 1999-09-30 |
DK0966283T3 (da) | 2006-10-09 |
DE69736130D1 (de) | 2006-07-27 |
ES2267148T3 (es) | 2007-03-01 |
YU5199A (sh) | 2000-10-30 |
AU739614B2 (en) | 2001-10-18 |
ATE329592T1 (de) | 2006-07-15 |
WO1998006400A2 (en) | 1998-02-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HD1A | Correction of address | ||
KB4A | Valid patent at the end of a year |
Effective date: 20031231 |
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KB4A | Valid patent at the end of a year |
Effective date: 20041231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20051231 |
|
GB1A | Change in the ownership or in the address of the owner | ||
KB4A | Valid patent at the end of a year |
Effective date: 20061231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20071231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20081231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20091231 |
|
KB4A | Valid patent at the end of a year |
Effective date: 20101231 |
|
MM4A | Lapsed by not paying the annual fees |
Effective date: 20110806 |