EE200100339A - Kombineeritud kemoteraapia - Google Patents

Kombineeritud kemoteraapia

Info

Publication number
EE200100339A
EE200100339A EEP200100339A EEP200100339A EE200100339A EE 200100339 A EE200100339 A EE 200100339A EE P200100339 A EEP200100339 A EE P200100339A EE P200100339 A EEP200100339 A EE P200100339A EE 200100339 A EE200100339 A EE 200100339A
Authority
EE
Estonia
Prior art keywords
combined chemotherapy
chemotherapy
combined
Prior art date
Application number
EEP200100339A
Other languages
English (en)
Inventor
Carleton Gowan Richard
Sebolt-Leopold Judith
Original Assignee
Warner-Lambert Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company filed Critical Warner-Lambert Company
Publication of EE200100339A publication Critical patent/EE200100339A/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/475Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
EEP200100339A 1998-12-22 1999-12-21 Kombineeritud kemoteraapia EE200100339A (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11329198P 1998-12-22 1998-12-22
US16478899P 1999-11-10 1999-11-10
PCT/US1999/030485 WO2000037141A1 (en) 1998-12-22 1999-12-21 Combination chemotherapy

Publications (1)

Publication Number Publication Date
EE200100339A true EE200100339A (et) 2002-10-15

Family

ID=26810891

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100339A EE200100339A (et) 1998-12-22 1999-12-21 Kombineeritud kemoteraapia

Country Status (31)

Country Link
EP (1) EP1140291B1 (et)
JP (1) JP2002532570A (et)
KR (1) KR20010099877A (et)
CN (1) CN1333698A (et)
AP (1) AP2001002175A0 (et)
AT (1) ATE310567T1 (et)
AU (1) AU2203900A (et)
BG (1) BG105715A (et)
BR (1) BR9916839A (et)
CA (1) CA2352326A1 (et)
CZ (1) CZ20012139A3 (et)
DE (1) DE69928568T2 (et)
EA (1) EA200100687A1 (et)
EE (1) EE200100339A (et)
ES (1) ES2253928T3 (et)
GE (1) GEP20043172B (et)
HK (1) HK1042057A1 (et)
HR (1) HRP20010473A2 (et)
HU (1) HUP0104844A3 (et)
ID (1) ID30250A (et)
IL (1) IL143939A0 (et)
IS (1) IS5969A (et)
MA (1) MA26768A1 (et)
NO (1) NO20013099L (et)
NZ (1) NZ512859A (et)
OA (1) OA11733A (et)
PL (1) PL348326A1 (et)
SK (1) SK8712001A3 (et)
TR (1) TR200101871T2 (et)
WO (1) WO2000037141A1 (et)
YU (1) YU45401A (et)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013169858A1 (en) 2012-05-08 2013-11-14 The Broad Institute, Inc. Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy
US8637246B2 (en) 2010-02-25 2014-01-28 Dana-Farber Cancer Institute, Inc. BRAF mutations conferring resistance to BRAF inhibitors
US9084781B2 (en) 2008-12-10 2015-07-21 Novartis Ag MEK mutations conferring resistance to MEK inhibitors
US11078540B2 (en) 2010-03-09 2021-08-03 Dana-Farber Cancer Institute, Inc. Methods of diagnosing and treating cancer in patients having or developing resistance to a first cancer therapy

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE05450B1 (et) 2000-07-19 2011-08-15 Warner-Lambert Company 4-jodofenlaminobenshdroksaamhapete oksgeenitud estrid, nende kristallvormid ja farmatseutilised kompositsioonid ning kasutamine
AU2001288562B2 (en) 2000-09-01 2006-10-05 The Government Of The United States Of America, As Represented By The Secretary Of Health And Human Services Inhibition of mitogen-activated protein kinase (MAPK) pathway: a selective therapeutic strategy against melanoma
AU2002255852B2 (en) * 2001-03-22 2006-11-09 Van Andel Research Institute Anthrax lethal factor inhibits tumor growth and angiogenesis
NZ518726A (en) 2001-05-09 2004-06-25 Warner Lambert Co Method of treating or inhibiting neutrophil chemotaxis by administering a mek inhibitor
CZ20022216A3 (cs) * 2001-07-02 2003-05-14 Warner-Lambert Company Kombinační chemoterapie
BRPI0415018A (pt) * 2003-10-08 2006-11-28 Teijin Pharma Ltd métodos para a produção de derivados de aminopirrolidina e de antranilamida, e, composto
MXPA06004363A (es) 2003-10-21 2006-06-14 Warner Lambert Co Forma polimorfica de la n-[(r)-2, 3-dihidroxipropoxi]-3, 4-difluoro-2 -(2-fluoro-4- yodofenilamino) benzamida.
DK1802579T3 (da) * 2004-10-20 2014-01-20 Merck Serono Sa Derivater af 3-arylaminopyridin
CN1807413B (zh) * 2005-09-28 2010-05-05 中国医学科学院医药生物技术研究所 咔唑磺酰胺衍生物及其制备方法
JP5129143B2 (ja) 2005-10-07 2013-01-23 エグゼリクシス, インコーポレイテッド Mekインヒビターおよびその使用方法
EP1790342A1 (de) 2005-11-11 2007-05-30 Zentaris GmbH Pyridopyrazin-Derivate und deren Verwendung als Modulatoren der Signaltransduktionswege
WO2007054556A1 (de) 2005-11-11 2007-05-18 Æterna Zentaris Gmbh Neue pyridopyrazine und deren verwendung als modulatoren von kinasen
US8217042B2 (en) 2005-11-11 2012-07-10 Zentaris Gmbh Pyridopyrazines and their use as modulators of kinases
PL2101759T3 (pl) 2006-12-14 2019-05-31 Exelixis Inc Sposoby stosowania inhibitorów MEK
CN103301096B (zh) * 2012-03-14 2015-05-06 中国中化股份有限公司 取代二苯胺类化合物作为制备抗肿瘤药物的应用
TR201807861T4 (tr) 2012-10-12 2018-06-21 Exelixis Inc Kanser tedavisinde kullanım için bileşikler yapmak için yeni işlem.
US10139415B2 (en) 2013-02-27 2018-11-27 Daiichi Sankyo Company, Limited Method for predicting responsiveness to compound inhibiting MAPK signal transduction pathway
CN105384754B (zh) * 2014-09-02 2018-04-20 上海科州药物研发有限公司 作为蛋白激酶抑制剂的杂环类化合物及其制备方法和用途
CN111909053B (zh) * 2020-08-06 2022-12-06 湖北省生物农药工程研究中心 基于二芳胺单元的酰胺类衍生物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL112248A0 (en) * 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
WO1997032604A1 (en) * 1996-03-07 1997-09-12 Novartis Ag Antiproliferative combinations, containing raf-targeted oligonucleotides and chemotherapeutic compounds
US6251943B1 (en) * 1997-02-28 2001-06-26 Warner-Lambert Company Method of treating or preventing septic shock by administering a MEK inhibitor
WO1998042830A2 (en) * 1997-03-21 1998-10-01 Board Of Regents, The University Of Texas System Noey2 gene compositions and methods of use
US6002008A (en) * 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
US6040321A (en) * 1997-11-12 2000-03-21 Bristol-Myers Squibb Company Aminothiazole inhibitors of cyclin dependent kinases
US5959097A (en) * 1998-11-20 1999-09-28 Isis Pharmaceuticals, Inc. Antisense modulation of MEK2 expression

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9084781B2 (en) 2008-12-10 2015-07-21 Novartis Ag MEK mutations conferring resistance to MEK inhibitors
US8637246B2 (en) 2010-02-25 2014-01-28 Dana-Farber Cancer Institute, Inc. BRAF mutations conferring resistance to BRAF inhibitors
US9279144B2 (en) 2010-02-25 2016-03-08 Dana-Farber Cancer Institute, Inc. Screening method for BRAF inhibitors
EP3028699A1 (en) 2010-02-25 2016-06-08 Dana-Farber Cancer Institute, Inc. Braf mutations conferring resistance to braf inhibitors
US11078540B2 (en) 2010-03-09 2021-08-03 Dana-Farber Cancer Institute, Inc. Methods of diagnosing and treating cancer in patients having or developing resistance to a first cancer therapy
WO2013169858A1 (en) 2012-05-08 2013-11-14 The Broad Institute, Inc. Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy

Also Published As

Publication number Publication date
CN1333698A (zh) 2002-01-30
NZ512859A (en) 2004-06-25
OA11733A (en) 2005-05-12
AP2001002175A0 (en) 2001-06-21
DE69928568T2 (de) 2006-07-27
EA200100687A1 (ru) 2001-12-24
IS5969A (is) 2001-06-14
SK8712001A3 (en) 2002-02-05
NO20013099D0 (no) 2001-06-21
MA26768A1 (fr) 2004-12-20
KR20010099877A (ko) 2001-11-09
BG105715A (en) 2002-04-30
CZ20012139A3 (cs) 2002-01-16
TR200101871T2 (tr) 2001-10-22
EP1140291B1 (en) 2005-11-23
ATE310567T1 (de) 2005-12-15
DE69928568D1 (de) 2005-12-29
BR9916839A (pt) 2001-10-09
GEP20043172B (en) 2004-02-25
HUP0104844A2 (en) 2002-06-29
EP1140291A1 (en) 2001-10-10
CA2352326A1 (en) 2000-06-29
NO20013099L (no) 2001-08-20
IL143939A0 (en) 2002-04-21
AU2203900A (en) 2000-07-12
PL348326A1 (en) 2002-05-20
ES2253928T3 (es) 2006-06-01
WO2000037141A9 (en) 2000-12-07
HUP0104844A3 (en) 2003-05-28
HK1042057A1 (zh) 2002-08-02
HRP20010473A2 (en) 2002-08-31
YU45401A (sh) 2004-07-15
WO2000037141A1 (en) 2000-06-29
JP2002532570A (ja) 2002-10-02
ID30250A (id) 2001-11-15

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